Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes

Biochemical and Biophysical Research Communications

Volumn 273, Issue 1, 2000, Pages 333-341

  Runge, Dieter ^a,b   Köhler, Christoph ^a   Kostrubsky, Vsevolod E ^b   Jäger, Dana ^a   Lehmann, Thomas ^a   Runge, Dorothee M ^a,b   May, Ursula ^a   Stolz, Donna Beer ^b   Strom, Stephen C ^b   Fleig, Wolfgang E ^a   Michalopoulos, George K ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Antibiotics; Aromatic hydrocarbons; Barbiturates; Cytochrome P450; Human hepatocytes; Multidrug resistance associated protein; P glycoprotein

Indexed keywords

3 METHYLCHOLANTHRENE; BETA NAPHTHOFLAVONE; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; ETHOXYRESORUFIN DEETHYLASE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; PHENACETIN O DEETHYLASE; PHENOBARBITAL; RIFAMPICIN;

ARTICLE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME;

EID: 0343526338     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2902     Document Type: Article

References (47)

1. Kocarek T. A., Schuetz E. G., Strom S. C., Fisher R. A., Guzelian P. S. Drug Metab. Dispos. 23:1995;415-421.
2. Silva J. M., Morin P. E., Day S. H., Kennedy B. P., Payette P., Rushmore T., Yergey Y. A., Nicoll-Griffith D. A. Drug Metab. Dispos. 26:1998;490-496.
3. Moshage H., Yap S. H. J. Hepatol. 15:1992;404-413.
4. Li A. P., Maurel P., Gómez-Lechón M. J., Cheng L. C., Jurima-Romet M. Chemico. Biol. Interact. 107:1997;5-16.
5. Kane R. E., Li A. E., Kaminski D. R. Drug Metab. Dispos. 23:1995;303-307.
6. Kono Y., Yang S., Roberts E. A. In Vitro Cell. Dev. Biol. 33:1997;467-472.
7. Donato M. T., Gómez-Lechón M. J., Jover R., Nakamura T., Castell J. V. J. Pharmacol. Exp. Therapeutics. 284:1998;760-767.
8. Ferrini J. B., Pichard L., Domergue J., Maurel P. Chemico.-Biol. Interactions. 107:1997;31-45.
9. Langouët S., Coles B., Morel F., Beaune P., Guengerich F. P., Ketterer B., Guillouzo A. Cancer Res. 55:1995;5574-5579.
10. Chang T. K. H., Yu L., Maurel P., Waxman D. J. Cancer Res. 57:1997;1946-1954.
11. Li A. P., Reith M. K., Rasmussen A., Gorski J. C., Hall S. D., Xu L., Kaminski D. L., Cheng L. K. Chemico-Biol. Interact. 107:1997;17-30.
12. Runge D. M., Runge D., Dorko K., Pisarov L. A., Leckel K., Kostrubsky V. E., Thomas D., Strom S. C., Michalopoulos G. K. J. Hepatol. 30:1999;365-274.
13. Runge D., Runge D. M., Jäger D., Lubecki K. A., Beer Stolz D., Karathanasis S., Kietzmann T., Strom S. C., Jungermann K., Fleig W. E., Michalopoulos G. K. Biochem. Biophys. Res. Comm. 269:2000;46-53.
14. Liddle C., Goodwin B. J., George J., Tapner M., Farrell G. C. J. Clin. Endocrin. Metab. 83:1998;2411-2416.
15. Shima N., Tsuda E., Goto M., Yano K., Hayasaka H., Ueda M. Biochem. Biophys. Res. Comm. 200:1994;808-815.
16. Strom S. C., Dorko K., Thompson M. T., Pisarov L. A., Nüssler A. K. Franco D., Boudjema K., Varet B. Îlots de Langerhans et Hépatocytes. Vers une Utilisation Therapeutique. 1998;195-205 Les editions Inserm, Paris.
17. Runge D., Runge D. M., Bowen W. C., Locker J., Michalopoulos G. K. Biol. Chem. 378:1997;873-881.
18. Lowry O. N., Rosebrough N. J., Farr A. L., Randall R. J. J. Biol. Chem. 193:1951;265-275.
19. Laemmli U. K. Nature. 227:1970;680-685.
20. Kostrubsky V. E., Strom S. C., Wood S. G., Wrighton S. A., Sinclair P. R., Sinclair J. F. Arch. Biochem. Biophys. 322:1995;516-520.
21. Kostrubsky V. E, Lewis L. D., Strom S. C., Wood S. G., Schuetz E. G., Schuetz J. D., Sinclair P. R., Wrighton S. A., Sinclair J. F. Arch. Biochem. Biophys. 355:1998;131-136.
22. Wrighton S. A., Brian W. R., Sari A. A., Iwasaki M., Guengerich P. F., Raucy J. L., Molowa D. T., Vandenbranden M. Mol. Pharmacol. 38:1990;207-213.
23. Noonan K. E., Beck C., Holzmayer T. A., Chin J. E., Wunder J. S., Andrulis I. L., Gazdar A. F., Willman C. L., Griffith B., von Hoff D. D., Roninson I. B. Proc. Natl. Acad. Sci USA. 87:1990;7160-7164.
24. Barrand M. A., Heppell-Parton A. C., Wright K. A., Rabbitts P. H., Twentyman P. R. J. Natl. Cancer Inst. 86:1994;110-117.
25. Stein U., Walther W., Laurencot C. M., Scheffer G. L., Scheper R. J., Shoemaker R. H. J. Natl. Cancer Inst. 11:1997;807-813.
26. Jantsch, B. 1997, Dissertation, University of Leipzig.
27. Donato M. T., Gómez-Lechón M. J., Castell J. V. Anal. Biochem. 213:1993;29-33.
28. Lubinski J., Flint O. P., Durham S. K. In vitro Toxicol. 7:1994;13-23.
29. Kostrubsky V. E., Ramachandran V., Venkataramanan R., Dorko K., Esplen J. E., Zhang S., Sinclair J. F., Wrighton S. A., Strom S. C. Drug Metab. Dispos. 27:1999;887-894.
30. Pichard-Garcia L., Hyland R., Baulieu J., Fabre J. M., Milton A., Maurel P. Drug Metab. Dispos. 28:2000;51-57.
31. Kronbach T., Fischer V., Meyer U. A. Clin. Pharmacol. Therapeutics. 43:1988;630-635.
32. Kronbach T., Mathys D., Umeno M., Gonzalez F. J., Meyer U. A. Mol. Pharmacol. 36:1989;89-96.
33. Watkins P. B., Wrighton S. A., Maurel P., Schuetz E. G., Mendez-Picon G., Parker G. A., Guzelian P. S. Proc. Natl. Acad. Sci. USA. 82:1985;6310-6314.
34. Brian W. R., Sari M. A., Iwasaki M., Shimada T., Kaminsky L. S., Guengerich F. P. Biochemistry. 29:1990;11280-11292.
35. Bargetzi M. J., Aoyama T., Gonzalez F. J., Meyer U. A. Clin. Pharm. Therapeutics. 46:1989;521-752.
36. Guengerich F. P., Brian W. R., Iwasaki M., Sari M. A., Bäärnhielm C., Berntsson P. J. Med. Chem. 34:1991;1838-1844.
37. Trautwein C., Rakemann T., Obermayer-Straub P., Niehof M., Manns M. P. J. Hepatol. 261:1997;48-54.
38. Ronis, M. J. J, and, Ingelman-Sundberg, M. 1999, ISSX Short Course Manual, Budapest.
39. Zilly W., Breimer D. D., Richter E. Eur. J Clin. Pharmacol. 11:1977;287-293.
40. Silverman J. A., Schrenk D. FASEB J. 11:1997;308-313.
41. Schuurhuis G. J., Broxterman H. J., de Lange J. H., Pinedo H. M., van Heijningen T. H., Kuiper C. M., Scheffer G. L., Scheper R. J., van Kalken C. K., Baak J. P. Br. J. Cancer. 64:1991;857-861.
42. Cordon-Cardo C., O'Brien J. P., Boccia J., Casals D., Bertino J. R., Melamed M. R. J. Histochem. Cytochem. 38:1990;1277-1287.
43. Mayer R., Kartenbeck J., Büchler M., Jedlitschky G., Leier I., Keppler D. J. Cell Biol. 131:1995;137-150.
44. Sugarawa I., Akiyama S., Scheper R. J., Itoyama S. Cancer Lett. 112:1997;23-31.
45. Gant T. W., Silverman J. A., Bisgaard H. C., Burt R. K., Marino P. A., Thorgeirsson S. S. Mol. Carcinogen. 4:1991;499-509.
46. Chieli E., Sontoni-Rugio E., Cervelli F., Sabatini A., Petrini M., Romiti N., Paolicchi A., Tongiani R. Carcinogenesis. 15:1994;335-341.
47. Schuetz E. G., Schuetz J. D., Thompson M. T., Fisher R. A., Madariage J. R, Strom S. C. Mol. Carcinogen. 12:1995;61-65.