The identification of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans

Carcinogenesis

Volumn 20, Issue 4, 1999, Pages 705-713

  Malfatti, Michael A ^a   Kulp, Kristen S ^a   Knize, Mark G ^a   Davis, Cindy ^c   Massengill, Joyce P ^c   Williams, Suzanne ^c   Nowell, Susan ^b   MacLeod, Stewart ^b   Dingley, Karen H ^a   Turteltaub, Kenneth W ^a   Lang, Nicholas P ^b,c   Felton, James S ^a  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c Special Treatment Section   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE DERIVATIVE; BIOLOGICAL MARKER; CARBON 14; CARCINOGEN; GLUCURONIDE; HETEROCYCLIC AMINE; PYRIDINE DERIVATIVE; 2 AMINO 1 METHYL 6 PHENYLIMIDAZO(4,5 B)PYRIDINE; 2-AMINO-1-METHYL-6-PHENYLIMIDAZO(4,5-B)PYRIDINE; CYTOCHROME P450 1A2; GLUCURONIC ACID; IMIDAZOLE DERIVATIVE;

AGED; ARTICLE; BLOOD LEVEL; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CASE REPORT; COLON CANCER; COOKING; DIET; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MASS SPECTROMETRY; MEAT; METABOLITE; PRIORITY JOURNAL; RADIOACTIVITY; RISK; STANDARD; URINALYSIS; ANIMAL; BIOTRANSFORMATION; BLOOD; CHEMICAL STRUCTURE; COLON TUMOR; COMPARATIVE STUDY; DOG; ENZYMOLOGY; GENETICS; HEAT; LIVER MICROSOME; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; PHENOTYPE; SPECIES DIFFERENCE; URINE;

ADMINISTRATION, ORAL; AGED; AGED, 80 AND OVER; ANIMALS; BIOTRANSFORMATION; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLONIC NEOPLASMS; CYTOCHROME P-450 CYP1A2; DOGS; GLUCURONATES; HEAT; HUMANS; IMIDAZOLES; MALE; MEAT; MICE; MICROSOMES, LIVER; MOLECULAR STRUCTURE; PHENOTYPE; SPECIES SPECIFICITY;

EID: 0032586869     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.4.705     Document Type: Article

References (43)

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