-
1
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:2001;608-675.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 608-675
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
2
-
-
0000926038
-
Recent advances in research on the insect prophenoloxidase cascade
-
Brey, P.T., Hultmark, D., (Eds.)
-
Ashida, M., Brey, P., 1997. Recent advances in research on the insect prophenoloxidase cascade. In: Brey, P.T., Hultmark, D., (Eds.), Molecular Mechanisms of Immune Responses in Insects. Chapman and Hall, London, pp. 133-172.
-
(1997)
Molecular Mechanisms of Immune Responses in Insects. Chapman and Hall, London
, pp. 133-172
-
-
Ashida, M.1
Brey, P.2
-
3
-
-
0028785577
-
Role of the integument in insect defence: Prophenoloxidase cascade in the cuticular matrix
-
Ashida M., Brey P. Role of the integument in insect defence: prophenoloxidase cascade in the cuticular matrix. Proc. Natl. Acad. Sci. USA. 92:1995;10698-10702.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10698-10702
-
-
Ashida, M.1
Brey, P.2
-
4
-
-
0029730738
-
A conserved signalling pathway: The Drosophila Toll-dorsal pathway
-
Belvin M.P., Anderson K.V. A conserved signalling pathway: the Drosophila Toll-dorsal pathway. Annu. Rev. Cell Dev. Biol. 12:1996;393-416.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 393-416
-
-
Belvin, M.P.1
Anderson, K.V.2
-
5
-
-
0346157328
-
Thioester-containing proteins and insect immunity
-
Blandin, S., Levashina, E.A., 2004. Thioester-containing proteins and insect immunity. Molec. Immun. 40, 903-908.
-
(2004)
Molec. Immun.
, vol.40
, pp. 903-908
-
-
Blandin, S.1
Levashina, E.A.2
-
6
-
-
0036848010
-
Sequential activation of signalling pathways during innate immunity in Drosophila
-
Boutros M., Agaisse H., Perrimon N. Sequential activation of signalling pathways during innate immunity in Drosophila. Dev. Cell. 3:2002;711-722.
-
(2002)
Dev. Cell
, vol.3
, pp. 711-722
-
-
Boutros, M.1
Agaisse, H.2
Perrimon, N.3
-
7
-
-
0033022730
-
Antimicrobial peptides in insects; Structure and function
-
Bulet P., Hetru C., Hoffmann D. Antimicrobial peptides in insects; structure and function. Dev. Comp. Immunol. 23:1999;329-344.
-
(1999)
Dev. Comp. Immunol.
, vol.23
, pp. 329-344
-
-
Bulet, P.1
Hetru, C.2
Hoffmann, D.3
-
8
-
-
0032530359
-
Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila
-
Chen P., Rodriguez A., Erskine R., Thach T., Abrams J.M. Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila. Dev. Biol. 201:1998;202-216.
-
(1998)
Dev. Biol.
, vol.201
, pp. 202-216
-
-
Chen, P.1
Rodriguez, A.2
Erskine, R.3
Thach, T.4
Abrams, J.M.5
-
9
-
-
0037066464
-
Requirement for a peptidoglycan recognition protein PGRP in Relish activation and antibacterial immune responses in Drosophila
-
Choe K-M., Werner T., Stoven S., Hultmark D., Anderson K.V. Requirement for a peptidoglycan recognition protein PGRP in Relish activation and antibacterial immune responses in Drosophila. Science. 296:2002;359-361.
-
(2002)
Science
, vol.296
, pp. 359-361
-
-
Choe, K.-M.1
Werner, T.2
Stoven, S.3
Hultmark, D.4
Anderson, K.V.5
-
10
-
-
0030640032
-
Activation of prophenoloxydase A1 by an activating enzyme in Drosophila melanogaster
-
Chosa N., Fukumitsu T., Fujimoto K., Ohnishi E. Activation of prophenoloxydase A1 by an activating enzyme in Drosophila melanogaster. Insect Biochem. Mol. Biol. 27:1997;61-68.
-
(1997)
Insect Biochem. Mol. Biol.
, vol.27
, pp. 61-68
-
-
Chosa, N.1
Fukumitsu, T.2
Fujimoto, K.3
Ohnishi, E.4
-
11
-
-
0035940514
-
Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
-
De Gregorio E., Spellman P.T., Rubin G.M., Lemaitre B. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proc. Natl. Acad. Sci. USA. 98:2001;12590-12595.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12590-12595
-
-
De Gregorio, E.1
Spellman, P.T.2
Rubin, G.M.3
Lemaitre, B.4
-
12
-
-
0037013856
-
The Toll and IMD pathways are the major regulators of immune response in Drosophila
-
De Gregorio E., Spellman P.T., Tzou P., Rubin G.M., Lemaitre B. The Toll and IMD pathways are the major regulators of immune response in Drosophila. EMBO J. 21:2002a;2568-2579.
-
(2002)
EMBO J.
, vol.21
, pp. 2568-2579
-
-
De Gregorio, E.1
Spellman, P.T.2
Tzou, P.3
Rubin, G.M.4
Lemaitre, B.5
-
13
-
-
18644376155
-
An immune-responsive serpin regulates the melanisation cascade in Drosophila
-
De Gregorio E., Han S-J., Lee W-J., Baek M-J., Osaki T., Kawabata S-I.et al. An immune-responsive serpin regulates the melanisation cascade in Drosophila. Dev. Cell. 3:2002b;1-20.
-
(2002)
Dev. Cell
, vol.3
, pp. 1-20
-
-
De Gregorio, E.1
Han, S.-J.2
Lee, W.-J.3
Baek, M.-J.4
Osaki, T.5
Kawabata, S.-I.6
-
14
-
-
0029840669
-
Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defence of Drosophila
-
Dushay M.S., Asling B., Hultmark D. Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defence of Drosophila. Proc. Natl. Acad. Sci. USA. 93:1996;10343-10347.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10343-10347
-
-
Dushay, M.S.1
Asling, B.2
Hultmark, D.3
-
15
-
-
0028326047
-
The Drosophila 18wheeler is required for morphogenesis and has striking similarities to Toll
-
Eldon, E., et al., 1994. The Drosophila 18wheeler is required for morphogenesis and has striking similarities to Toll, Development 120, 885-899.
-
(1994)
Development
, vol.120
, pp. 885-899
-
-
Eldon, E.1
-
16
-
-
0034729655
-
Interactions between the cellular and humoral immune responses in Drosophila
-
Elrod-Erickson M., Mishra S., Schneider D. Interactions between the cellular and humoral immune responses in Drosophila. Curr. Biol. 10:2000;781-784.
-
(2000)
Curr. Biol.
, vol.10
, pp. 781-784
-
-
Elrod-Erickson, M.1
Mishra, S.2
Schneider, D.3
-
17
-
-
0027220975
-
KappaB-like motifs regulate the induction of immune genes in Drosophila
-
Engstrom Y., Kadalayil L., Sun S-C.et al. KappaB-like motifs regulate the induction of immune genes in Drosophila. J. Mol. Biol. 232:1993;327-333.
-
(1993)
J. Mol. Biol.
, vol.232
, pp. 327-333
-
-
Engstrom, Y.1
Kadalayil, L.2
Sun, S.-C.3
-
18
-
-
0032473360
-
A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway
-
Ferrandon D., Jung A.C., Criqui M., Lemaitre B., Uttenweiler-Joseph S., Michaut L., Reichhart J., Hoffmann J.A. A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. EMBO J. 17:1998;1217-1227.
-
(1998)
EMBO J.
, vol.17
, pp. 1217-1227
-
-
Ferrandon, D.1
Jung, A.C.2
Criqui, M.3
Lemaitre, B.4
Uttenweiler-Joseph, S.5
Michaut, L.6
Reichhart, J.7
Hoffmann, J.A.8
-
19
-
-
0037133631
-
Epithelia: Not just physical barriers
-
Ganz T. Epithelia: not just physical barriers. Proc. Natl. Acad. Sci. USA. 99:2002;3357-3358.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3357-3358
-
-
Ganz, T.1
-
20
-
-
0026486817
-
Cactus a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates
-
Geisler R., Bergmann A., Hiromi Y., Nusslein-Volhard C. Cactus a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates. Cell. 71:1992;613-621.
-
(1992)
Cell
, vol.71
, pp. 613-621
-
-
Geisler, R.1
Bergmann, A.2
Hiromi, Y.3
Nusslein-Volhard, C.4
-
21
-
-
18044400563
-
Drosophila immune deficiency (IMD) is a death domain protein that activates the antibacterial defence and can promote apoptosis
-
Georgel P.et al. Drosophila immune deficiency (IMD) is a death domain protein that activates the antibacterial defence and can promote apoptosis. Dev. Cell. 1:2001;503-514.
-
(2001)
Dev. Cell
, vol.1
, pp. 503-514
-
-
Georgel, P.1
-
22
-
-
0037061450
-
The Drosophila immune response against Gram negative bacteria is mediated by a putative membrane peptidoglycan recognition protein
-
Gottar M.et al. The Drosophila immune response against Gram negative bacteria is mediated by a putative membrane peptidoglycan recognition protein. Nature. 416:2002;640-644.
-
(2002)
Nature
, vol.416
, pp. 640-644
-
-
Gottar, M.1
-
23
-
-
0033762437
-
The necrotic gene in Drosophila corresponds in one of a cluster of three serpin transcripts mapping at 43A1.2
-
Green C., Levashina E.A., McKimmie C., Dafforn T., Reichhart J-M., Gubb D. The necrotic gene in Drosophila corresponds in one of a cluster of three serpin transcripts mapping at 43A1.2. Genetics. 156:2000;1117-1127.
-
(2000)
Genetics
, vol.156
, pp. 1117-1127
-
-
Green, C.1
Levashina, E.A.2
McKimmie, C.3
Dafforn, T.4
Reichhart, J.-M.5
Gubb, D.6
-
24
-
-
0027200622
-
Genetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster
-
Heitzler P.et al. Genetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster. Genetics. 135:1993;105-115.
-
(1993)
Genetics
, vol.135
, pp. 105-115
-
-
Heitzler, P.1
-
26
-
-
0036167107
-
Drosophila innate immunity: An evolutionary perspective
-
Hoffmann J.A., Reichhart J-M. Drosophila innate immunity: an evolutionary perspective. Nat. Immunol. 3:2002;121-126.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 121-126
-
-
Hoffmann, J.A.1
Reichhart, J.-M.2
-
27
-
-
0035940499
-
Drosophila Myd88 is an adapter in the Toll signalling pathway
-
Horng T., Medzhitov R. Drosophila Myd88 is an adapter in the Toll signalling pathway. Proc. Natl. Acad. Sci. USA. 98:2001;12654-12658.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12654-12658
-
-
Horng, T.1
Medzhitov, R.2
-
28
-
-
0034613376
-
DFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD
-
Hu S., Yang X. dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD. J. Biol. Chem. 275:2000;30761-30764.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30761-30764
-
-
Hu, S.1
Yang, X.2
-
29
-
-
0037124314
-
Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway
-
Igaki T., Kanda H., Yamamoto-Goto Y., Kanuka H., Kuranaga E., Aigaki T., Miura M. Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway. EMBO J. 21:2002;3009-3018.
-
(2002)
EMBO J.
, vol.21
, pp. 3009-3018
-
-
Igaki, T.1
Kanda, H.2
Yamamoto-Goto, Y.3
Kanuka, H.4
Kuranaga, E.5
Aigaki, T.6
Miura, M.7
-
31
-
-
0035909905
-
A genome-wide analysis of immune responses in Drosophila
-
Irving P., Troxler L., Heuer T.S., Belvin M., Kopczynski C., Reichhart J-M., Hoffmann J.A., Hetru C. A genome-wide analysis of immune responses in Drosophila. Proc. Natl. Acad. Sci. USA. 98:2001;15119-15124.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15119-15124
-
-
Irving, P.1
Troxler, L.2
Heuer, T.S.3
Belvin, M.4
Kopczynski, C.5
Reichhart, J.-M.6
Hoffmann, J.A.7
Hetru, C.8
-
32
-
-
0027443688
-
Dif, a dorsal-related gene that mediates an immune response in Drosophila
-
Ip Y.T.et al. Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell. 75:1993;753-753.
-
(1993)
Cell
, vol.75
, pp. 753-753
-
-
Ip, Y.T.1
-
33
-
-
0031012783
-
Characterisation and functional analysis of 12 naturally occurring reactive site variants of serpin-1 from Manduca sexta
-
Jiang H., Kanost M.R. Characterisation and functional analysis of 12 naturally occurring reactive site variants of serpin-1 from Manduca sexta. J. Biol. Chem. 272:1997;1082-1087.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1082-1087
-
-
Jiang, H.1
Kanost, M.R.2
-
34
-
-
0032514618
-
Pro-Phenoloxydase activating proteinase from an insect, Manduca sexta: A bacteria-inducible protein similar to Drosophila easter
-
Jiang H., Wang Y., Kanost M.R. Pro-Phenoloxydase activating proteinase from an insect, Manduca sexta: a bacteria-inducible protein similar to Drosophila easter. Proc. Natl. Acad. Sci. USA. 95:1998;12220-12225.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12220-12225
-
-
Jiang, H.1
Wang, Y.2
Kanost, M.R.3
-
35
-
-
0033953792
-
The clip-domain family of serine proteinases in arthropods
-
Jiang H., Kanost M.R. The clip-domain family of serine proteinases in arthropods. Insect Biochem. Mol. Biol. 30:2000;95-105.
-
(2000)
Insect Biochem. Mol. Biol.
, vol.30
, pp. 95-105
-
-
Jiang, H.1
Kanost, M.R.2
-
36
-
-
0036952124
-
Tissue and stage-specific expression of the Tolls in Drosophila embryos
-
Kambris Z., Hoffmann J.A., Imler J-L., Capovilla M. Tissue and stage-specific expression of the Tolls in Drosophila embryos. Mech. Dev. 2:2002;311-317.
-
(2002)
Mech. Dev.
, vol.2
, pp. 311-317
-
-
Kambris, Z.1
Hoffmann, J.A.2
Imler, J.-L.3
Capovilla, M.4
-
37
-
-
0037047362
-
Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling
-
Kanda H., Igaki T., Kanuka H., Yagi T., Miura M. Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling. J. Biol. Chem. 277:2002;28372-28375.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28372-28375
-
-
Kanda, H.1
Igaki, T.2
Kanuka, H.3
Yagi, T.4
Miura, M.5
-
38
-
-
0027402290
-
Insect immunity: Two 17-bp repeats nesting a kappaB-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila
-
Kappler C., Meister M., Lagueux M.et al. Insect immunity: two 17-bp repeats nesting a kappaB-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila. EMBO J. 12:1993;1561-1568.
-
(1993)
EMBO J.
, vol.12
, pp. 1561-1568
-
-
Kappler, C.1
Meister, M.2
Lagueux, M.3
-
39
-
-
0025685240
-
The Drosophila membrane receptor Toll can function to promote cellular adhesion
-
Keith F.J., Gay N.J. The Drosophila membrane receptor Toll can function to promote cellular adhesion. EMBO J. 9:1990;4299-4306.
-
(1990)
EMBO J.
, vol.9
, pp. 4299-4306
-
-
Keith, F.J.1
Gay, N.J.2
-
40
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
-
Kelliher M.A., Grimm S., Ishida Y., Kuo F., Stanger B.Z., Leder P. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity. 8:1998;297-303.
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
41
-
-
0037108474
-
A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade
-
Khush R.S., Cornwell W.D., Uram J.N., Lemaitre B. A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade. Curr. Biol. 20:2002;1728-1737.
-
(2002)
Curr. Biol.
, vol.20
, pp. 1728-1737
-
-
Khush, R.S.1
Cornwell, W.D.2
Uram, J.N.3
Lemaitre, B.4
-
42
-
-
0034693324
-
Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysacchride and beta-1,3-glucan that mediates the signalling for the induction of innate immune genes in Drosophila melanogaster cells
-
Kim Y.S.et al. Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysacchride and beta-1,3-glucan that mediates the signalling for the induction of innate immune genes in Drosophila melanogaster cells. J. Biol. Chem. 275:2000;32721-32727.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32721-32727
-
-
Kim, Y.S.1
-
43
-
-
0035321067
-
The evolution and genetics of innate immunity
-
Kimbrel A.D., Beutler B. The evolution and genetics of innate immunity. Nat. Rev. Genet. 2:2001;1-13.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 1-13
-
-
Kimbrel, A.D.1
Beutler, B.2
-
44
-
-
0343415656
-
A lipopolysaccharide- and beta-1,3-glucan-binding protein from hemocytes of the freshwater crayfish Pacifastacus leniusculus. Purification, characterization, and cDNA clonino
-
Lee S.Y., Wang R., Soderhall K. A lipopolysaccharide- and beta-1,3-glucan-binding protein from hemocytes of the freshwater crayfish Pacifastacus leniusculus. Purification, characterization, and cDNA clonino. J. Biol. Chem. 275:2000;1337-1343.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1337-1343
-
-
Lee, S.Y.1
Wang, R.2
Soderhall, K.3
-
45
-
-
0028865526
-
A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defence
-
Lemaitre B., Kromer-Metzger E., Michaut L.et al. A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defence. Proc. Natl. Acad. Sci. USA. 92:1995;9465-9469.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9465-9469
-
-
Lemaitre, B.1
Kromer-Metzger, E.2
Michaut, L.3
-
46
-
-
0030595339
-
The dorsoventral regulatory gene cassette spaetzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B., Nicolas E., Michaut L., Reichhart J-M., Hoffmann J.A. The dorsoventral regulatory gene cassette spaetzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 86:1996;973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.-M.4
Hoffmann, J.A.5
-
47
-
-
0031446642
-
Drosophila host defence: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B., Reichhart J-M., Hoffmann J.A. Drosophila host defence: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc. Natl. Acad. Sci. USA. 94:1997;14614-14619.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B.1
Reichhart, J.-M.2
Hoffmann, J.A.3
-
49
-
-
0026030444
-
Genetic and molecular characterisation of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity
-
Letsou A., Alexander S., Orth K., Wasserman S.A. Genetic and molecular characterisation of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. Proc. Natl. Acad. Sci. USA. 88:1991;810-814.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 810-814
-
-
Letsou, A.1
Alexander, S.2
Orth, K.3
Wasserman, S.A.4
-
50
-
-
0033578917
-
Constitutive activation of Toll-mediated antifungal defence in serpin-deficient Drosophila
-
Levashina E.A.et al. Constitutive activation of Toll-mediated antifungal defence in serpin-deficient Drosophila. Science. 285:1999;1917-1919.
-
(1999)
Science
, vol.285
, pp. 1917-1919
-
-
Levashina, E.A.1
-
51
-
-
0037011189
-
A serpin mutant links Toll activation to melanization in the host defense of Drosophila
-
Ligoxygakis P., Pelte N., Ji Ch., Leclerc V., Duvic B., Belvin M., Jiang H., Hoffmann J.A., Reichhart J-M. A serpin mutant links Toll activation to melanization in the host defense of Drosophila. EMBO J. 21:2002a;6330-6337.
-
(2002)
EMBO J.
, vol.21
, pp. 6330-6337
-
-
Ligoxygakis, P.1
Pelte, N.2
Ji, Ch.3
Leclerc, V.4
Duvic, B.5
Belvin, M.6
Jiang, H.7
Hoffmann, J.A.8
Reichhart, J.-M.9
-
52
-
-
0037025213
-
Activation of Drosophila Toll during fungal infection by a blood serine protease
-
Ligoxygakis P., Pelte N., Hoffmann J.A., Reichhart J-M. Activation of Drosophila Toll during fungal infection by a blood serine protease. Science. 297:2002b;114-116.
-
(2002)
Science
, vol.297
, pp. 114-116
-
-
Ligoxygakis, P.1
Pelte, N.2
Hoffmann, J.A.3
Reichhart, J.-M.4
-
53
-
-
0034305744
-
The Drosophila caspase Dredd is required to resist gram-negative bacterial infection
-
Leulier F., Rodriguez A., Khush R.S., Abrams J.M., Lemaitre B. The Drosophila caspase Dredd is required to resist gram-negative bacterial infection. EMBO Rep. 1:2000;353-358.
-
(2000)
EMBO Rep.
, vol.1
, pp. 353-358
-
-
Leulier, F.1
Rodriguez, A.2
Khush, R.S.3
Abrams, J.M.4
Lemaitre, B.5
-
54
-
-
0037172656
-
Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults
-
Leulier F., Vidal S., Saigo K., Ueda R., Lemaitre B. Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults. Curr. Biol. 12:2002;996-1000.
-
(2002)
Curr. Biol.
, vol.12
, pp. 996-1000
-
-
Leulier, F.1
Vidal, S.2
Saigo, K.3
Ueda, R.4
Lemaitre, B.5
-
55
-
-
0038664357
-
The Drosophila immune system detects bacteria through specific peptidoglycan recognition
-
Leulier F., Parquet C., Pili-Floury S., Ryu J.H., Caroff M., Lee W.J., Mengin-Lecreulx D., Lemaitre B. The Drosophila immune system detects bacteria through specific peptidoglycan recognition. Nat. Immunol. 4:2003;478-484.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 478-484
-
-
Leulier, F.1
Parquet, C.2
Pili-Floury, S.3
Ryu, J.H.4
Caroff, M.5
Lee, W.J.6
Mengin-Lecreulx, D.7
Lemaitre, B.8
-
56
-
-
0035187882
-
The antibacterial arm of the Drosophila innate immune response requires an IkappaB kinase
-
Lu Y., Wu L.P., Anderson K.V. The antibacterial arm of the Drosophila innate immune response requires an IkappaB kinase. Genes Dev. 15:2001;104-110.
-
(2001)
Genes Dev.
, vol.15
, pp. 104-110
-
-
Lu, Y.1
Wu, L.P.2
Anderson, K.V.3
-
57
-
-
0033564614
-
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins dorsal and DIF
-
Manfruelli P., Reichhart J-M., Steward R., Hoffmann J.A., Lemaitre B. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins dorsal and DIF. EMBO J. 18:1999;3380-3391.
-
(1999)
EMBO J.
, vol.18
, pp. 3380-3391
-
-
Manfruelli, P.1
Reichhart, J.-M.2
Steward, R.3
Hoffmann, J.A.4
Lemaitre, B.5
-
58
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburn P., Janeway C.A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:1997;394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburn, P.2
Janeway Jr., C.A.3
-
59
-
-
0028559509
-
Insect immunity: A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter
-
Meister M., Braun A., Kappler C., Reichhart J-M., Hoffmann J.A. Insect immunity: a transgenic analysis in Drosophila defines several functional domains in the diptericin promoter. EMBO J. 13:1994;5958-5966.
-
(1994)
EMBO J.
, vol.13
, pp. 5958-5966
-
-
Meister, M.1
Braun, A.2
Kappler, C.3
Reichhart, J.-M.4
Hoffmann, J.A.5
-
60
-
-
0035856990
-
Drosophila Toll is activated by Gram-positive bacteria via a circulating peptidoglycan recognition protein
-
Michel T., Reichhart J-M., Hoffmann J.A., Royet J. Drosophila Toll is activated by Gram-positive bacteria via a circulating peptidoglycan recognition protein. Nature. 414:2001;756-759.
-
(2001)
Nature
, vol.414
, pp. 756-759
-
-
Michel, T.1
Reichhart, J.-M.2
Hoffmann, J.A.3
Royet, J.4
-
61
-
-
0037162294
-
Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily
-
Moreno E., Yan M., Basler K. Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Curr. Biol. 12:2002;1263-1268.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1263-1268
-
-
Moreno, E.1
Yan, M.2
Basler, K.3
-
62
-
-
0036850985
-
The Drosophila immune defence against Gram-negative infection requires the death domain protein FADD
-
Naitza S.et al. The Drosophila immune defence against Gram-negative infection requires the death domain protein FADD. Immunity. 17:2002;576-591.
-
(2002)
Immunity
, vol.17
, pp. 576-591
-
-
Naitza, S.1
-
63
-
-
0027620526
-
Melanogenesis and the generation of cytotoxic molecules during insect cellular immune reactions
-
Nappi A.J., Vass E. Melanogenesis and the generation of cytotoxic molecules during insect cellular immune reactions. Pigment Cell. Res. 6:1993;117-126.
-
(1993)
Pigment Cell. Res.
, vol.6
, pp. 117-126
-
-
Nappi, A.J.1
Vass, E.2
-
64
-
-
0029582852
-
Superoxide anion generation in Drosophila during melanotic encapsulation of parasites
-
Nappi A.J., Vass E., Frey F., Carton Y. Superoxide anion generation in Drosophila during melanotic encapsulation of parasites. Eur. J. Cell Biol. 68:1995;450-456.
-
(1995)
Eur. J. Cell Biol.
, vol.68
, pp. 450-456
-
-
Nappi, A.J.1
Vass, E.2
Frey, F.3
Carton, Y.4
-
65
-
-
0024297132
-
Purification of a beta-1,3-glucan recognition protein in the prophenoloxidase activating system from hemolymph of the silkworm, Bombyx mori
-
Ochiai M., Ashida M. Purification of a beta-1,3-glucan recognition protein in the prophenoloxidase activating system from hemolymph of the silkworm, Bombyx mori. J. Biol. Chem. 263:1988;12056-12062.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 12056-12062
-
-
Ochiai, M.1
Ashida, M.2
-
66
-
-
0035065782
-
The imd gene is required for local Cecropin expression in Drosophila barrier epithelia
-
Onfelt Tingvall T., Roos E., Engstrom Y. The imd gene is required for local Cecropin expression in Drosophila barrier epithelia. EMBO Rep. 2:2001;239-243.
-
(2001)
EMBO Rep.
, vol.2
, pp. 239-243
-
-
Onfelt Tingvall, T.1
Roos, E.2
Engstrom, Y.3
-
67
-
-
0036166242
-
The Drosophila Toll-9 activates a constitutive antimicrobial defense
-
Ooi J.Y., Yagi Y., Hu X., Ip Y.T. The Drosophila Toll-9 activates a constitutive antimicrobial defense. EMBO Rep. 3:2002;82-87.
-
(2002)
EMBO Rep.
, vol.3
, pp. 82-87
-
-
Ooi, J.Y.1
Yagi, Y.2
Hu, X.3
Ip, Y.T.4
-
68
-
-
0034732383
-
Immunological detection of serpin in the fall webworm, Hyphandria cunea, and its inhibitory activity on the prophenoloxidase system
-
Park D.S., Shin S.W., Hong S.D., Park H.Y. Immunological detection of serpin in the fall webworm, Hyphandria cunea, and its inhibitory activity on the prophenoloxidase system. Mol. Cells. 10:2000;186-192.
-
(2000)
Mol. Cells
, vol.10
, pp. 186-192
-
-
Park, D.S.1
Shin, S.W.2
Hong, S.D.3
Park, H.Y.4
-
69
-
-
0032509295
-
Defective LPS signalling in C3H/Hej and C57BL/10ScCr mice have mutations in Tr14 gene
-
Poltorak A.et al. Defective LPS signalling in C3H/Hej and C57BL/10ScCr mice have mutations in Tr14 gene. Science. 282:1998;2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
-
70
-
-
0016345880
-
Microbial activation of prophenoloxidase from immune insect larvae
-
Pye A.E. Microbial activation of prophenoloxidase from immune insect larvae. Nature. 251:1974;610-613.
-
(1974)
Nature
, vol.251
, pp. 610-613
-
-
Pye, A.E.1
-
71
-
-
0037061482
-
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E.coli
-
Ramet M., Manfruelli P., Pearson A., Mathey-Prevot B., Ezekowitz R.A. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E.coli. Nature. 416:2002;644-648.
-
(2002)
Nature
, vol.416
, pp. 644-648
-
-
Ramet, M.1
Manfruelli, P.2
Pearson, A.3
Mathey-Prevot, B.4
Ezekowitz, R.A.5
-
72
-
-
0033711445
-
The Rel protein DIF mediates the antifungal but not the antibacterial host defence in Drosophila
-
Rutschmann S., Jung A.C., Hetru C., Reichhart J-M., Hoffmann J.A., Ferrandon D. The Rel protein DIF mediates the antifungal but not the antibacterial host defence in Drosophila. Immunity. 12:2000a;569-580.
-
(2000)
Immunity
, vol.12
, pp. 569-580
-
-
Rutschmann, S.1
Jung, A.C.2
Hetru, C.3
Reichhart, J.-M.4
Hoffmann, J.A.5
Ferrandon, D.6
-
73
-
-
0034303573
-
Role of Drosophila IKKγ in a Toll-independent antibacterial immune response
-
Rutschmann S., Jung A.C., Zhou R., Silverman N., Hoffmann J.A., Ferrandon D. Role of Drosophila IKKγ in a Toll-independent antibacterial immune response. Nat. Immunol. 1:2000b;342-347.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 342-347
-
-
Rutschmann, S.1
Jung, A.C.2
Zhou, R.3
Silverman, N.4
Hoffmann, J.A.5
Ferrandon, D.6
-
74
-
-
0033537866
-
Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation
-
Sakurai H., Miyoshi H., Toriumi W., Sugita T. Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation. J. Biol. Chem. 274:1999;10641-10648.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10641-10648
-
-
Sakurai, H.1
Miyoshi, H.2
Toriumi, W.3
Sugita, T.4
-
75
-
-
0027499132
-
Pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo
-
Shelton C.A., Wasserman S.A. Pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo. Cell. 72:1993;515-525.
-
(1993)
Cell
, vol.72
, pp. 515-525
-
-
Shelton, C.A.1
Wasserman, S.A.2
-
76
-
-
0032415862
-
Phosphorylation modulates direct interactions between the Toll receptor, pelle kinase and tube
-
Shen B., Manley J.L. Phosphorylation modulates direct interactions between the Toll receptor, pelle kinase and tube. Development. 125:1998;4719-4728.
-
(1998)
Development
, vol.125
, pp. 4719-4728
-
-
Shen, B.1
Manley, J.L.2
-
77
-
-
0034287444
-
A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity
-
Silverman N., Zhou R., Stoven S., Pandey N., Hultmark D., Maniatis T. A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev. 14:2000;2461-2471.
-
(2000)
Genes Dev.
, vol.14
, pp. 2461-2471
-
-
Silverman, N.1
Zhou, R.2
Stoven, S.3
Pandey, N.4
Hultmark, D.5
Maniatis, T.6
-
78
-
-
0035883151
-
NF-κB signalling pathways in mammalian and insect immunity
-
Silverman N., Maniatis T. NF-κB signalling pathways in mammalian and insect immunity. Genes Dev. 15:2001;2321-2332.
-
(2001)
Genes Dev.
, vol.15
, pp. 2321-2332
-
-
Silverman, N.1
Maniatis, T.2
-
79
-
-
0032005367
-
Role of the prophenoloxidase-activating system in invertebrate immunity
-
Söderhäll K., Cerenius L. Role of the prophenoloxidase- activating system in invertebrate immunity. Curr. Opin. Immunol. 10:1998;23-28.
-
(1998)
Curr. Opin. Immunol.
, vol.10
, pp. 23-28
-
-
Söderhäll, K.1
Cerenius, L.2
-
80
-
-
0029054725
-
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
-
Stanger B.Z., Leder P., Lee T.H., Kim E., Seed B. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell. 81:1995;513-523.
-
(1995)
Cell
, vol.81
, pp. 513-523
-
-
Stanger, B.Z.1
Leder, P.2
Lee, T.H.3
Kim, E.4
Seed, B.5
-
81
-
-
0031860827
-
The dorsal-related immunity factor (Dif) can define the dorsal-ventral axis of polarity in the Drosophila embryo
-
Stein D., Goltz J.S., Jurcsak J., Stevens L. The dorsal-related immunity factor (Dif) can define the dorsal-ventral axis of polarity in the Drosophila embryo. Development. 11:1998;2159-2169.
-
(1998)
Development
, vol.11
, pp. 2159-2169
-
-
Stein, D.1
Goltz, J.S.2
Jurcsak, J.3
Stevens, L.4
-
82
-
-
0019386682
-
Sequence and specificity of two antibacterial proteins involved in insect immunity
-
Steiner H., Hultmark D., Engström A., Bennich H., Boman H.G. Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature. 292:1981;246-248.
-
(1981)
Nature
, vol.292
, pp. 246-248
-
-
Steiner, H.1
Hultmark, D.2
Engström, A.3
Bennich, H.4
Boman, H.G.5
-
83
-
-
0023619362
-
Dorsal, an embryonic polarity gene in Drosophila is homologous to the vertebrate proto-oncogene, c-rel
-
Steward R. Dorsal, an embryonic polarity gene in Drosophila is homologous to the vertebrate proto-oncogene, c-rel. Science. 238:1987;692-694.
-
(1987)
Science
, vol.238
, pp. 692-694
-
-
Steward, R.1
-
84
-
-
0034303480
-
Activation of the NF-κB factor Relish by rapid endoproteolytic cleavage
-
Stoven S., Ando I., Kadalayil L., Engstrom Y., Hultmark D. Activation of the NF-κB factor Relish by rapid endoproteolytic cleavage. EMBO Rep. 1:2000;347-352.
-
(2000)
EMBO Rep.
, vol.1
, pp. 347-352
-
-
Stoven, S.1
Ando, I.2
Kadalayil, L.3
Engstrom, Y.4
Hultmark, D.5
-
85
-
-
0038284956
-
Caspase-mediated processing of the Drosophila NF-kappa B factor Relish
-
Stoven S., Silverman N., Junell A., Hedengren-Olcott M., Erturk D., Engstrom Y., Maniatis T., Hultmark D. Caspase-mediated processing of the Drosophila NF-kappa B factor Relish. Proc. Natl. Acad. Sci. USA. 100:2003;5991-5996.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5991-5996
-
-
Stoven, S.1
Silverman, N.2
Junell, A.3
Hedengren-Olcott, M.4
Erturk, D.5
Engstrom, Y.6
Maniatis, T.7
Hultmark, D.8
-
86
-
-
0037108754
-
Over-expression of a pattern recognition receptor, peptidoglycan recognition protein-LE, activates imd/relish mediated antibacterial defence and the phenoloxidase cascade in Drosophila larvae
-
Takehana A., Katsuyama T., Yano T., Oshima Y., Takada H., Aigaki T., Kurata S. Over-expression of a pattern recognition receptor, peptidoglycan recognition protein-LE, activates imd/relish mediated antibacterial defence and the phenoloxidase cascade in Drosophila larvae. Proc. Natl. Acad. Sci. USA. 99:2002;13705-13710.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13705-13710
-
-
Takehana, A.1
Katsuyama, T.2
Yano, T.3
Oshima, Y.4
Takada, H.5
Aigaki, T.6
Kurata, S.7
-
87
-
-
0034641738
-
Toll-related receptors and the control of antimicrobial expression in Drosophila
-
Tauszig S., Jouanguy E., Hoffmann J.A., Imler J.L. Toll-related receptors and the control of antimicrobial expression in Drosophila. Proc. Natl. Acad. Sci. USA. 97:2000;10520-10525.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10520-10525
-
-
Tauszig, S.1
Jouanguy, E.2
Hoffmann, J.A.3
Imler, J.L.4
-
88
-
-
0036141954
-
Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
-
Tauszig-Delamasure S., Bilak H., Capovilla M., Hoffmann J.A., Imler J.L. Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections. Nat. Immunol. 3:2002;91-97.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 91-97
-
-
Tauszig-Delamasure, S.1
Bilak, H.2
Capovilla, M.3
Hoffmann, J.A.4
Imler, J.L.5
-
89
-
-
0033638404
-
Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia
-
Tzou P., Ohresser S., Ferrandon D., Capovilla M., Reichhart J.M., Lemaitre B., Hoffmann J.A., Imler J.L. Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia. Immunity. 13:2000;737-748.
-
(2000)
Immunity
, vol.13
, pp. 737-748
-
-
Tzou, P.1
Ohresser, S.2
Ferrandon, D.3
Capovilla, M.4
Reichhart, J.M.5
Lemaitre, B.6
Hoffmann, J.A.7
Imler, J.L.8
-
90
-
-
0035423794
-
Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses
-
Vidal S., Khush R.S., Leulier F., Tzou P., Nakamura M., Lemaitre B. Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses. Genes Dev. 15:2001;1900-1912.
-
(2001)
Genes Dev.
, vol.15
, pp. 1900-1912
-
-
Vidal, S.1
Khush, R.S.2
Leulier, F.3
Tzou, P.4
Nakamura, M.5
Lemaitre, B.6
-
91
-
-
0034610370
-
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
-
Werner T.et al. A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster. Proc. Natl. Acad. Sci. USA. 97:2000;13772-13776.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13772-13776
-
-
Werner, T.1
-
92
-
-
0038036294
-
Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan
-
Werner T., Borge-Renberg K., Mellroth P., Steiner H., Hultmark D. Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan. J. Biol. Chem. 278:2003;26319-26322.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26319-26322
-
-
Werner, T.1
Borge-Renberg, K.2
Mellroth, P.3
Steiner, H.4
Hultmark, D.5
-
93
-
-
0029884417
-
Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori
-
Yoshida H., Kinoshita K., Ashida M. Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori. J. Biol. Chem. 271:1996;13854-13860.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13854-13860
-
-
Yoshida, H.1
Kinoshita, K.2
Ashida, M.3
|