Local calcium signaling in neurons

Neuron

Volumn 40, Issue 2, 2003, Pages 331-346

  Augustine, George J ^a   Santamaria, Fidel ^a   Tanaka, Keiko ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CELL PROTEIN; SYNAPTOTAGMIN;

BRAIN NERVE CELL; CALCIUM TRANSPORT; CELL ACTIVITY; DENDRITE; EXOCYTOSIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NERVE ENDING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SYNAPSE;

EID: 0141987862     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(03)00639-1     Document Type: Review

References (221)

1. Abe T., Saisu H., Horikawa H.P. Synaptocanalins (N-type Ca channel-associated proteins) form a complex with SNAP-25 and synaptotagmin. Ann. N Y Acad. Sci. 707:1993;373-375.
2. Adler E.M., Augustine G.J., Duffy S.N., Charlton M.P. Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse. J. Neurosci. 11:1991;1496-1507.
3. Ahmari S.E., Buchanan J., Smith S.J. Assembly of presynaptic active zones from cytoplasmic transport packets. Nat. Neurosci. 3:2000;445-451.
4. v1.2) in a cooperative manner. J. Biol. Chem. 278:2003;29231-29239.
5. Augustine G.J. Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current. J. Physiol. 431:1990;343-364.
6. Augustine G.J. How does calcium trigger neurotransmitter release? Curr. Opin. Neurobiol. 11:2001;320-326.
7. Augustine G.J., Charlton M.P., Smith S.J. Calcium entry and transmitter release at voltage-clamped nerve terminals of squid. J. Physiol. 367:1985;163-181.
8. Augustine G.J., Adler E.M., Charlton M.P. The calcium signal for transmitter secretion from presynaptic nerve terminals. Ann. N Y Acad. Sci. 635:1991;365-381.
9. Barry M.F., Ziff E.B. Receptor trafficking and the plasticity of excitatory synapses. Curr. Opin. Neurobiol. 12:2002;279-286.
10. Bayer K.U., De Koninck P., Leonard A.S., Hell J.W., Schulman H. Interaction with the NMDA receptor locks CaMKII in an active conformation. Nature. 411:2001;801-805.
11. Bear M.F., Linden D.J. The mechanisms and meaning of long-term synaptic depression in the mammalian brain. Cowan W.M., Sudhof T.C., Stevens C.F. In Synapses. 2001;Johns Hopkins Press, Baltimore, MD. 455-517.pp.
12. Bennett M.K., Calakos N., Scheller R.H. Syntaxin. a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones Science. 257:1992;255-259.
13. Bergsman J.B., Tsien R.W. Syntaxin modulation of calcium channels in cortical synaptosomes as revealed by botulinum toxin C1. J. Neurosci. 20:2000;4368-4378.
14. Berridge M.J. Neuronal calcium signaling. Neuron. 21:1998;13-26.
15. Beutner D., Voets T., Neher E., Moser T. Calcium dependence of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse. Neuron. 29:2001;681-690.
16. Bezprozvanny I., Watras J., Ehrlich B.E. Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature. 351:1991;751-754.
17. Bezprozvanny I., Scheller R.H., Tsien R.W. Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature. 378:1995;623-626.
18. Blackstone C., Sheng M. Postsynaptic calcium signaling microdomains in neurons. Front. Biosci. 7:2002;d872-d885.
19. Bofill-Cardona E., Vartian N., Nanoff C., Freissmuth M., Boehm S. Two different signaling mechanisms involved in the excitation of rat sympathetic neurons by uridine nucleotides. Mol. Pharmacol. 57:2000;1165-1172.
20. Bollmann J.H., Sakmann B., Borst J.G. Calcium sensitivity of glutamate release in a calyx-type terminal. Science. 289:2000;953-957.
21. 2+ signals. J. Cell Sci. 114:2001;2213-2222.
22. Borst J.G., Sakmann B. Calcium influx and transmitter release in a fast CNS synapse. Nature. 383:1996;431-434.
23. Burns M.E., Augustine G.J. Synaptic structure and function. dynamic organization yields architectural precision Cell. 83:1995;187-194.
24. Burrone J., Neves G., Gomis A., Cooke A., Lagnado L. Endogenous calcium buffers regulate fast exocytosis in the synaptic terminal of retinal bipolar cells. Neuron. 33:2002;101-112.
25. Caillard O., Ben-Ari Y., Gaiarsa J.L. Activation of presynaptic and postsynaptic ryanodine-sensitive calcium stores is required for the induction of long-term depression at GABAergic synapses in the neonatal rat hippocampus amphetamine. J. Neurosci. 20:2000;RC94.
26. Cao Y.J., Peng Y.Y. Caffeine and carbonyl cyanide m-chlorophenylhydrazone increased evoked and spontaneous release of luteinizing hormone-releasing hormone from intact presynaptic terminals. Neuroscience. 92:1999;1511-1521.
27. 2+ channels and SNARE proteins in neurotransmitter release. Ann. N Y Acad. Sci. 868:1999;144-159.
28. Chad J.E., Eckert R. Calcium domains associated with individual channels can account for anomalous voltage relations of Ca-dependent responses. Biophys. J. 45:1984;993-999.
29. 2+ sensor that triggers exocytosis? Nat. Rev. Mol. Cell Biol. 3:2002;498-508.
30. 1A subunit of the P/Q-type calcium channel. EMBO J. 16:1997;4591-4596.
31. 2+ concentration triggering exocytosis in neuroendocrine cells. Proc. Natl. Acad. Sci. USA. 91:1994;12765-12769.
32. Coghlan V.M., Perrino B.A., Howard M., Langeberg L.K., Hicks J.B., Gallatin W.M., Scott J.D. Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science. 267:1995;108-111.
33. v2.3 (R-type). J. Biol. Chem. 278:2003;9258-9266.
34. Colledge M., Dean R.A., Scott G.K., Langeberg L.K., Huganir R.L., Scott J.D. Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex. Neuron. 27:2000;107-119.
35. Conroy W.G., Liu Z., Nai Q., Coggan J.S., Berg D.K. PDZ-containing proteins provide a functional postsynaptic scaffold for nicotinic receptors in neurons. Neuron. 38:2003;759-771.
36. Crank J. The Mathematics of Diffusion. Second Edition:1975;Oxford University Press, Oxford.
37. 2+ stores in rat sympathetic neurons. Proc. Natl. Acad. Sci. USA. 95:1998;7151-7156.
38. 2+ and assembly with the core SNARE complex onto membranes. Neuron. 24:1999;363-376.
39. Deisseroth K., Mermelstein P.G., Xia H., Tsien R.W. Signaling from synapse to nucleus. the logic behind the mechanisms Curr. Opin. Neurobiol. 13:2003;354-365.
40. 2+ mobilisation in rat sympathetic neurones, but this signalling pathway does not mediate M-current inhibition. J. Physiol. 520:1999;101-111.
41. 2+ stores Neuron. 36:2002;787-790.
42. 3 pathways in neurons. Neuron. 34:2002;209-220.
43. DiGregorio D.A., Peskoff A., Vergara J.L. Measurement of action potential-induced presynaptic calcium domains at a cultured neuromuscular junction. J. Neurosci. 19:1999;7846-7859.
44. Dosemeci A., Tao-Cheng J.H., Vinade L., Winters C.A., Pozzo-Miller L., Reese T.S. Glutamate-induced transient modification of the postsynaptic density. Proc. Natl. Acad. Sci. USA. 98:2001;10428-10432.
45. Dunaevsky A., Tashiro A., Majewska A., Mason C., Yuste R. Developmental regulation of spine motility in the mammalian central nervous system. Proc. Natl. Acad. Sci. USA. 96:1999;13438-13443.
46. 2+ channels in mammalian central neurons. Trends Neurosci. 18:1995;89-98.
47. Duprat F., Daw M., Lim W., Collingridge G., Isaac J. GluR2 protein-protein interactions and the regulation of AMPA receptors during synaptic plasticity. Philos. Trans. R. Soc. Lond. B Biol. Sci. 358:2003;715-720.
48. Edmonds B., Reyes R., Schwaller B., Roberts W.M. Calretinin modifies presynaptic calcium signaling in frog saccular hair cells. Nat. Neurosci. 3:2000;786-790.
49. Ehlers M.D., Zhang S., Bernhadt J.P., Huganir R.L. Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell. 84:1996;745-755.
50. 2+ signalling in fine dendrites and spines of cerebellar Purkinje neurons. Nature. 373:1995;155-158. a.
51. Eilers J., Callewaert G., Armstrong C., Konnerth A. Calcium signaling in a narrow somatic submembrane shell during synaptic activity in cerebellar Purkinje neurons. Proc. Natl. Acad. Sci. USA. 92:1995;10272-10276. b.
52. el Far O., Charvin N., Leveque C., Martin-Moutot N., Takahashi M., Seagar M.J. Interaction of a synaptobrevin (VAMP)-syntaxin complex with presynaptic calcium channels. FEBS Lett. 361:1995;101-105.
53. Emptage N., Bliss T.V., Fine A. Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines. Neuron. 22:1999;115-124.
54. 2+ entry, and spontaneous transmitter release. Neuron. 29:2001;197-208.
55. Engert F., Bonhoeffer T. Dendritic spine changes associated with hippocampal long-term synaptic plasticity. Nature. 399:1999;66-70.
56. Feng W., Tu J., Yang T., Vernon P.S., Allen P.D., Worley P.F., Pessah I.N. Homer regulates gain of ryanodine receptor type 1 channel complex. J. Biol. Chem. 277:2002;44722-44730.
57. Fiala J.C., Harris K.M. Dendritic structure. Stuart G., Spruston N., Hausser M. Dendrites. 1999;Oxford University Press, Oxford, UK.
58. Finch E.A., Augustine G.J. Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. Nature. 396:1998;753-756.
59. Finch E.A., Turner T.J., Goldin S.M. Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release. Science. 252:1991;443-446.
60. Fischer M., Kaech S., Knutti D., Matus A. Rapid actin-based plasticity in dendritic spines. Neuron. 20:1998;847-854.
61. Fischer M., Kaech S., Wagner U., Brinkhaus H., Matus A. Glutamate receptors regulate actin-based plasticity in dendritic spines. Nat. Neurosci. 3:2000;887-894.
62. i. J. Physiol. 450:1992;217-246.
63. Garner C.C., Nash J., Huganir R.L. PDZ domains in synapse assembly and signaling. Trends Cell Biol. 10:2000;274-280.
64. Golding N.L., Jung H.Y., Mickus T., Spruston N. Dendritic calcium spike initiation and repolarization are controlled by distinct potassium channel subtypes in CA1 pyramidal neurons. J. Neurosci. 19:1999;8789-8798.
65. Golding N.L., Staff N.P., Spruston N. Dendritic spikes as a mechanism for cooperative long-term potentiation. Nature. 418:2002;326-331.
66. Grab D.J., Berzins K., Cohen R.S., Siekevitz P. Presence of calmodulin in postsynaptic densities isolated from canine cerebral cortex. J. Biol. Chem. 254:1979;8690-8696.
67. i transient J. Mol. Cell. Cardiol. 34:2002;941-950.
68. Guthrie P.B., Segal M., Kater S.B. Independent regulation of calcium revealed by imaging dendritic spines. Nature. 354:1991;76-80.
69. Halpain S., Hipolito A., Saffer L. Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J. Neurosci. 18:1998;9835-9844.
70. Harris K.M. Structure, development, and plasticity of dendritic spines. Curr. Opin. Neurobiol. 9:1999;343-348.
71. Harris K.M., Kater S.B. Dendritic spines. cellular specializations imparting both stability and flexibility to synaptic function Annu. Rev. Neurosci. 17:1994;341-371.
72. Hartell N.A. Strong activation of parallel fibers produces localized calcium transients and a form of LTD that spreads to distant synapses. Neuron. 16:1996;601-610.
73. Heidelberger R., Heinemann C., Neher E., Matthews G. Calcium dependence of the rate of exocytosis in a synaptic terminal. Nature. 371:1994;513-515.
74. Hernandez-Cruz A., Sala F., Adams P.R. Subcellular calcium transients visualized by confocal microscopy in a voltage-clamped vertebrate neuron. Science. 247:1990;858-862.
75. Hillier B.J., Christopherson K.S., Prehoda K.E., Bredt D.S., Lim W.A. Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science. 284:1999;812-815.
76. Hoffman D.A., Sprengel R., Sakmann B. Molecular dissection of hippocampal theta-burst pairing potentiation. Proc. Natl. Acad. Sci. USA. 99:2002;7740-7745.
77. Horne J.H., Meyer T. Elementary calcium-release units induced by inositol trisphosphate. Science. 276:1997;1690-1693.
78. Horton A.C., Ehlers M.D. Neuronal Polarity and Trafficking. Neuron. 40:2003;277-295., this issue.
79. 2+-triggered exocytosis in presynaptic terminals. Neuron. 17:1996;501-512.
80. Iino M. Calcium release mechanisms in smooth muscle. Jpn. J. Pharmacol. 54:1990;345-354.
81. Inoue T., Kato K., Kohda K., Mikoshiba K. Type 1 inositol 1,4,5-trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons. J. Neurosci. 18:1998;5366-5373.
82. Ito M. Cerebellar long-term depression. characterization, signal transduction, and functional roles Physiol. Rev. 81:2001;1143-1195.
83. Jackson M.B., Konnerth A., Augustine G.J. Action potential broadening and frequency-dependent facilitation of calcium signals in pituitary nerve terminals. Proc. Natl. Acad. Sci. USA. 88:1991;380-384.
84. Jaffe L.F. Classes and mechanisms of calcium waves. Cell Calcium. 14:1993;736-745.
85. 2+ entry into hippocampal neurons. Nature. 357:1992;244-246.
86. 2+ compounds. J. Physiol. 494:1996;53-65.
87. Kato A., Ozawa F., Saitoh Y., Fukazawa Y., Sugiyama H., Inokuchi K. Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors. J. Biol. Chem. 273:1998;23969-23975.
88. Katz B. The Release of Neural Transmitter Substances. 1969;Liverpool University Press, Liverpool.
89. Kennedy M.B. Signal-processing machines at the postsynaptic density. Science. 290:2000;750-754.
90. Khodakhah K., Armstrong C.M. Induction of long-term depression and rebound potentiation by inositol trisphosphate in cerebellar Purkinje neurons. Proc. Natl. Acad. Sci. USA. 94:1997;14009-14014.
91. Khodakhah K., Ogden D. Functional heterogeneity of calcium release by inositol trisphosphate in single Purkinje neurones, cultured cerebellar astrocytes, and peripheral tissues. Proc. Natl. Acad. Sci. USA. 90:1993;4976-4980.
92. 2+ channels with presynaptic SNARE proteins. Proc. Natl. Acad. Sci. USA. 94:1997;14782-14786.
93. 2+ sensors for exocytosis in rat phaeochromocytoma cells. J. Physiol. 533:2001;627-637.
94. Klauck T.M., Faux M.C., Labudda K., Langeberg L.K., Jaken S., Scott J.D. Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science. 271:1996;1589-1592.
95. Knopfel T., Vranesic I., Staub C., Gahwiler B.H. Climbing fibre responses in olivo-cerebellar slice cultures. II. Dynamics of cytosolic calcium in purkinje cells. Eur. J. Neurosci. 3:1991;343-348.
96. Koester H.J., Sakmann B. Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials. Proc. Natl. Acad. Sci. USA. 95:1998;9596-9601.
97. 2+ sensor for neurotransmitter release. Trends Neurosci. 26:2003;413-422.
98. Konnerth A., Dreessen J., Augustine G.J. Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proc. Natl. Acad. Sci. USA. 89:1992;7051-7055.
99. Korkotian E., Segal M. Structure-function relations in dendritic spines. is size important? Hippocampus. 10:2000;587-595.
100. Korkotian E., Segal M. Spike-associated fast contraction of dendritic spines in cultured hippocampal neurons. Neuron. 30:2001;751-758.
101. 2+ signals in spines of hippocampal neurons. J. Neurosci. 20:2000;1791-1799.
102. Larkum M.E., Kaiser K.M., Sakmann B. Calcium electrogenesis in distal apical dendrites of layer 5 pyramidal cells at a critical frequency of back-propagating action potentials. Proc. Natl. Acad. Sci. USA. 96:1999;14600-14604.
103. 2+ waves in layer 2/3 and layer 5 rat neocortical pyramidal neurons. J. Physiol. 549:2003;471-488.
104. Lazarewicz J.W., Rybkowski W., Sadowski M., Ziembowicz A., Alaraj M., Wegiel J., Wisniewski H.M. N-methyl-D-aspartate receptor-mediated, calcium-induced calcium release in rat dentate gyrus/CA4 in vivo. J. Neurosci. Res. 51:1998;76-84.
105. Leonard A.S., Bayer K.U., Merrill M.A., Lim I.A., Shea M.A., Schulman H., Hell J.W. Regulation of calcium/calmodulin-dependent protein kinase II docking to N-methyl-D-aspartate receptors by calcium/calmodulin and α-actinin. J. Biol. Chem. 277:2002;48441-48448.
106. Liang Y., Yuan L.L., Johnston D., Gray R. Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus. J. Neurophysiol. 87:2002;1132-1137.
107. 2+ channels in sympathetic neurons. Neuron. 1:1988;355-365.
108. Llinas R., Steinberg I.Z., Walton K. Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse. Biophys. J. 33:1981;323-351.
109. Llinas R., Sugimori M., Silver R.B. Microdomains of high calcium concentration in a presynaptic terminal. Science. 256:1992;677-679.
110. Lohmann C., Myhr K.L., Wong R.O. Transmitter-evoked local calcium release stabilizes developing dendrites. Nature. 418:2002;177-181.
111. 2+ buffering in Purkinje neurons. Neuron. 24:1999;989-1002.
112. Mainen Z.F., Malinow R., Svoboda K. Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated. Nature. 399:1999;151-155.
113. Majewska A., Brown E., Ross J., Yuste R. Mechanisms of calcium decay kinetics in hippocampal spines. role of spine calcium pumps and calcium diffusion through the spine neck in biochemical compartmentalization J. Neurosci. 20:2000;1722-1734. a.
114. Majewska A., Tashiro A., Yuste R. Regulation of spine calcium dynamics by rapid spine motility. J. Neurosci. 20:2000;8262-8268. b.
115. Maletic-Savatic M., Malinow R., Svoboda K. Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science. 283:1999;1923-1927.
116. Malinow R., Malenka R.C. AMPA receptor trafficking and synaptic plasticity. Annu. Rev. Neurosci. 25:2002;103-126.
117. Markram H., Helm P.J., Sakmann B. Dendritic calcium transients evoked by single back-propagating action potentials in rat neocortical pyramidal neurons. J. Physiol. 485:1995;1-20.
118. Markram H., Roth A., Helmchen F. Competitive calcium binding. implications for dendritic calcium signaling J. Comput. Neurosci. 5:1998;331-348.
119. Martin-Moutot N., el Far O., Leveque C., David P., Marqueze B., Lang B., Newsom-Davis J., Hoshino T., Takahashi M., Seagar M.J. Synaptotagmin. a Lambert-Eaton myasthenic syndrome antigen that associates with presynaptic calcium channels J. Physiol. (Paris). 87:1993;37-41.
120. Martone M.E., Zhang Y., Simpliciano V.M., Carragher B.O., Ellisman M.H. Three-dimensional visualization of the smooth endoplasmic reticulum in Purkinje cell dendrites. J. Neurosci. 13:1993;4636-4646.
121. Matus A. Actin-based plasticity in dendritic spines. Science. 290:2000;754-758.
122. Meinrenken C.J., Borst J.G., Sakmann B. Calcium secretion coupling at calyx of held governed by nonuniform channel-vesicle topography. J. Neurosci. 22:2002;1648-1667.
123. Meir A., Ginsburg S., Butkevich A., Kachalsky S.G., Kaiserman I., Ahdut R., Demirgoren S., Rahamimoff R. Ion channels in presynaptic nerve terminals and control of transmitter release. Physiol. Rev. 79:1999;1019-1088.
124. Mintz I.M., Sabatini B.L., Regehr W.G. Calcium control of transmitter release at a cerebellar synapse. Neuron. 15:1995;675-688.
125. 2+ channels to synaptic vesicle exocytosis. Nature. 424:2003;939-948.
126. Miyakawa H., Lev-Ram V., Lasser-Ross N., Ross W.N. Calcium transients evoked by climbing fiber and parallel fiber synaptic inputs in guinea pig cerebellar Purkinje neurons. J. Neurophysiol. 68:1992;1178-1189. a.
127. 2+ channels. Neuron. 9:1992;1163-1173. b.
128. Miyata M., Finch E.A., Khiroug L., Hashimoto K., Hayasaka S., Oda S.I., Inouye M., Takagishi Y., Augustine G.J., Kano M. Local calcium release in dendritic spines required for long-term synaptic depression. Neuron. 28:2000;233-244.
129. 2+ channels. Neuron. 17:1996;781-788.
130. 2+ channels. Proc. Natl. Acad. Sci. USA. 95:1998;14523-14528.
131. Mochida S., Westenbroek R.E., Yokoyama C.T., Zhong H., Myers S.J., Scheuer T., Itoh K., Catterall W.A. Requirement for the synaptic protein interaction site for reconstitution of synaptic transmission by P/Q-type calcium channels. Proc. Natl. Acad. Sci. USA. 100:2003;2819-2824.
132. 2+ responses. Nature. 354:1991;73-76.
133. Naisbitt S., Kim E., Tu J.C., Xiao B., Sala C., Valtschanoff J., Weinberg R.J., Worley P.F., Sheng M. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron. 23:1999;569-582.
134. 3-sensitive stores evoked by synaptic activation of mGluRs paired with backpropagating action potentials. Neuron. 24:1999;727-737.
135. 2+ release evoked by metabotropic agonists and backpropagating action potentials in hippocampal CA1 pyramidal neurons. J. Neurosci. 20:2000;8365-8376.
136. Nakamura T., Lasser-Ross N., Nakamura K., Ross W.N. Spatial segregation and interaction of calcium signalling mechanisms in rat hippocampal CA1 pyramidal neurons. J. Physiol. 543:2002;465-480.
137. 2+ release mechanism involved in asynchronous exocytosis at frog motor nerve terminals. J. Gen. Physiol. 112:1998;593-609.
138. 2+ microdomains. new tools for understanding their roles in neurotransmitter release Neuron. 20:1998;389-399. a.
139. 2+ signals. Cell Calcium. 24:1998;345-357. b.
140. Neher E., Augustine G.J. Calcium gradients and buffers in bovine chromaffin cells. J. Physiol. 450:1992;273-301.
141. Nimchinsky E.A., Sabatini B.L., Svoboda K. Structure and function of dendritic spines. Annu. Rev. Physiol. 64:2002;313-353.
142. 2+ action on neuropeptide and acetylcholine release in Aplysia californica. J. Physiol. 535:2001;647-662.
143. 2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 75:1996;99-109.
144. Petersen O.H. Calcium signal compartmentalization. Biol. Res. 35:2002;177-182.
145. 2+ transients in dendritic spines of hippocampal pyramidal neurons in brain slice. Neuron. 14:1995;1223-1231.
146. Qian J., Saggau P. Modulation of transmitter release by action potential duration at the hippocampal CA3-CA1 synapse. J. Neurophysiol. 81:1999;288-298.
147. Rao A., Craig A.M. Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines. Hippocampus. 10:2000;527-541.
148. Regehr W.G., Atluri P.P. Calcium transients in cerebellar granule cell presynaptic terminals. Biophys. J. 68:1995;2156-2170.
149. Reid C.A., Fabian-Fine R., Fine A. Postsynaptic calcium transients evoked by activation of individual hippocampal mossy fiber synapses. J. Neurosci. 21:2001;2206-2214.
150. 2+ channel/syntaxin interaction. J. Neurosci. 17:1997;6647-6656.
151. Rios E., Stern M.D. Calcium in close quarters. microdomain feedback in excitation-contraction coupling and other cell biological phenomena Annu. Rev. Biophys. Biomol. Struct. 26:1997;47-82.
152. Roberts W.M. Spatial calcium buffering in saccular hair cells. Nature. 363:1993;74-76.
153. Roberts W.M. Localization of calcium signals by a mobile calcium buffer in frog saccular hair cells. J. Neurosci. 14:1994;3246-3262.
154. Roberts W.M., Jacobs R.A., Hudspeth A.J. Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells. J. Neurosci. 10:1990;3664-3684.
155. Ross W.N., Werman R. Mapping calcium transients in the dendrites of Purkinje cells from the guinea-pig cerebellum in vitro. J. Physiol. 389:1987;319-336.
156. 2+ buffers in facilitating and depressing nerve terminals of pyramidal cells in layer 2/3 of the rat neocortex indicates a target cell-specific difference in presynaptic calcium dynamics. J. Physiol. 531:2001;807-826.
157. 2+ signaling in dendritic spines. Curr. Opin. Neurobiol. 11:2001;349-356.
158. 2+ ions in dendritic spines. Neuron. 33:2002;439-452.
159. Sala C., Piech V., Wilson N.R., Passafaro M., Liu G., Sheng M. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron. 31:2001;115-130.
160. Scannevin R.H., Huganir R.L. Postsynaptic organization and regulation of excitatory synapses. Nat. Rev. Neurosci. 1:2000;133-141.
161. Schiavo G., Stenbeck G., Rothman J.E., Sollner T.H. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc. Natl. Acad. Sci. USA. 94:1997;997-1001.
162. Schiller J., Helmchen F., Sakmann B. Spatial profile of dendritic calcium transients evoked by action potentials in rat neocortical pyramidal neurons. J. Physiol. 487:1995;583-600.
163. Schiller J., Schiller Y., Stuart G., Sakmann B. Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons. J. Physiol. 505:1997;605-616.
164. Schiller J., Major G., Koester H.J., Schiller Y. NMDA spikes in basal dendrites of cortical pyramidal neurons. Nature. 404:2000;285-289.
165. Schmidt H., Brown E.B., Schwaller B., Eilers J. Diffusional mobility of parvalbumin in spiny dendrites of cerebellar purkinje neurons quantified by fluorescence recovery after photobleaching. Biophys. J. 84:2003;2599-2608. a.
166. 28k J. Physiol. 551:2003;13-32. b.
167. Schneggenburger R., Neher E. Intracellular calcium dependence of transmitter release rates at a fast central synapse. Nature. 406:2000;889-893.
168. Schneggenburger R., Zhou Z., Konnerth A., Neher E. Fractional contribution of calcium to the cation current through glutamate receptor channels. Neuron. 11:1993;133-143.
169. Seagar M., Leveque C., Charvin N., Marqueze B., Martin-Moutot N., Boudier J.A., Boudier J.L., Shoji-Kasai Y., Sato K., Takahashi M. Interactions between proteins implicated in exocytosis and voltage-gated calcium channels. Philos. Trans. R. Soc. Lond. B Biol. Sci. 354:1999;289-297.
170. Segal M. Rapid plasticity of dendritic spine. hints to possible functions? Prog. Neurobiol. 63:2001;61-70.
171. 2+-dependent electrostatic switch Neuron. 18:1997;133-142.
172. Shapira M., Zhai R.G., Dresbach T., Bresler T., Torres V.I., Gundelfinger E.D., Ziv N.E., Garner C.C. Unitary assembly of presynaptic active zones from Piccolo-Bassoon transport vesicles. Neuron. 38:2003;237-252.
173. Shen K., Meyer T. Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation. Science. 284:1999;162-166.
174. Sheng M., Kim M.J. Postsynaptic signaling and plasticity mechanisms. Science. 298:2002;776-780.
175. Sheng M., Pak D.T. Ligand-gated ion channel interactions with cytoskeletal and signaling proteins. Annu. Rev. Physiol. 62:2000;755-778.
176. 2+ channels with the C2B domain of synaptotagmin I. Proc. Natl. Acad. Sci. USA. 94:1997;5405-5410.
177. Silva A.J., Stevens C.F., Tonegawa S., Wang Y. Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice. Science. 257:1992;201-206.
178. Simon S.M., Llinas R.R. Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release. Biophys. J. 48:1985;485-498.
179. Sinha S.R., Wu L.G., Saggau P. Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses. Biophys. J. 72:1997;637-651.
180. Spira M.E., Oren R., Dormann A., Ilouz N., Lev S. Calcium, protease activation, and cytoskeleton remodeling underlie growth cone formation and neuronal regeneration. Cell. Mol. Neurobiol. 21:2001;591-604.
181. Stanley E.F. The calcium channel and the organization of the presynaptic transmitter release face. Trends Neurosci. 20:1997;404-409.
182. Star E.N., Kwiatkowski D.J., Murthy V.N. Rapid turnover of actin in dendritic spines and its regulation by activity. Nat. Neurosci. 5:2002;239-246.
183. 2+ pump. A study using specific antibodies. J. Biol. Chem. 270:1995;12184-12190.
184. Strack S., Colbran R.J. Autophosphorylation-dependent targeting of calcium/calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl- D-aspartate receptor. J. Biol. Chem. 273:1998;20689-20692.
185. Sudhof T.C. Synaptotagmins. why so many? J. Biol. Chem. 277:2002;7629-7632.
186. Svoboda K., Tank D.W., Denk W. Direct measurement of coupling between dendritic spines and shafts. Science. 272:1996;716-719.
187. Svoboda K., Denk W., Kleinfeld D., Tank D.W. In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature. 385:1997;757-760.
188. Svoboda K., Helmchen F., Denk W., Tank D.W. Spread of dendritic excitation in layer 2/3 pyramidal neurons in rat barrel cortex in vivo. Nat. Neurosci. 2:1999;65-73.
189. Swandulla D., Hans M., Zipser K., Augustine G.J. Role of residual calcium in synaptic depression and posttetanic potentiation. fast and slow calcium signaling in nerve terminals Neuron. 7:1991;915-926.
190. Takechi H., Eilers J., Konnerth A. A new class of synaptic response involving calcium release in dendritic spines. Nature. 396:1998;757-760.
191. 2+-ATPase, and calsequestrin J. Neurosci. 12:1992;489-505.
192. 2+. Cell Calcium. 32:2002;321-334.
193. Toni N., Buchs P.A., Nikonenko I., Bron C.R., Muller D. LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature. 402:1999;421-425.
194. Tu J.C., Xiao B., Yuan J.P., Lanahan A.A., Leoffert K., Li M., Linden D.J., Worley P.F. Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron. 21:1998;717-726.
195. Tu J.C., Xiao B., Naisbitt S., Yuan J.P., Petralia R.S., Brakeman P., Doan A., Aakalu V.K., Lanahan A.A., Sheng M., Worley P.F. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron. 23:1999;583-592.
196. 2+ channels in rat sensory neurons. J. Neurosci. 17:1997;7404-7414.
197. Verhage M., McMahon H.T., Ghijsen W.E., Boomsma F., Scholten G., Wiegant V.M., Nicholls D.G. Differential release of amino acids, neuropeptides, and catecholamines from isolated nerve terminals. Neuron. 6:1991;517-524.
198. Verkhratsky A. The endoplasmic reticulum and neuronal calcium signaling. Cell Calcium. 32:2002;393-404.
199. von Gersdorff H., Matthews G. Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminals. Nature. 367:1994;735-739.
200. von Gersdorff H., Sakaba T., Berglund K., Tachibana M. Submillisecond kinetics of glutamate release from a sensory synapse. Neuron. 21:1998;1177-1188.
201. 2+/calmodulin-dependent protein kinase II and α-actinin. J. Neurosci. 21:2001;423-433.
202. Wang S.S., Thompson S.H. Local positive feedback by calcium in the propagation of intracellular calcium waves. Biophys. J. 69:1995;1683-1697.
203. Wang S.S., Denk W., Hausser M. Coincidence detection in single dendritic spines mediated by calcium release. Nat. Neurosci. 3:2000;1266-1273.
204. Wei D.S., Mei Y.A., Bagal A., Kao J.P., Thompson S.M., Tang C.M. Compartmentalized and binary behavior of terminal dendrites in hippocampal pyramidal neurons. Science. 293:2001;2272-2275.
205. West A.E., Chen W.G., Dalva M.B., Dolmetsch R.E., Kornhauser J.M., Shaywitz A.J., Takasu M.A., Tao X., Greenberg M.E. Calcium regulation of neuronal gene expression. Proc. Natl. Acad. Sci. USA. 98:2001;11024-11031.
206. 2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals. J. Neurosci. 18:1998;6319-6330.
207. 2+ channels. EMBO J. 15:1996;4100-4110.
208. Wu L.G., Saggau P. Pharmacological identification of two types of presynaptic voltage-dependent calcium channels at CA3-CA1 synapses of the hippocampus. J. Neurosci. 14:1994;5613-5622.
209. Xiao B., Tu J.C., Petralia R.S., Yuan J.P., Doan A., Breder C.D., Ruggiero A., Lanahan A.A., Wenthold R.J., Worley P.F. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron. 21:1998;707-716.
210. Yamauchi T. Molecular constituents and phosphorylation-dependent regulation of the post-synaptic density. Mass Spectrom. Rev. 21:2002;266-286.
211. i elevation. J. Neurophysiol. 81:1999;781-787.
212. + channels. Nat. Neurosci. 3:2000;566-571.
213. Yuste R., Denk W. Dendritic spines as basic functional units of neuronal integration. Nature. 375:1995;682-684.
214. 2+ accumulations in dendrites of neocortical pyramidal neurons. an apical band and evidence for two functional compartments Neuron. 13:1994;23-43.
215. Yuste R., Majewska A., Cash S.S., Denk W. Mechanisms of calcium influx into hippocampal spines. heterogeneity among spines, coincidence detection by NMDA receptors, and optical quantal analysis J. Neurosci. 19:1999;1976-1987.
216. Zamponi G.W. Regulation of presynaptic calcium channels by synaptic proteins. J. Pharmacol. Sci. 92:2003;79-83.
217. Zhai R.G., Vardinon-Friedman H., Cases-Langhoff C., Becker B., Gundelfinger E.D., Ziv N.E., Garner C.C. Assembling the presynaptic active zone. a characterization of an active one precursor vesicle Neuron. 29:2001;131-143.
218. 2+-triggered exocytosis. Neuron. 34:2002;599-611.
219. 2+ channels by SNAP-25, syntaxin and synaptotagmin. Nat. Neurosci. 2:1999;939-941.
220. Zucker R.S. Calcium- and activity-dependent synaptic plasticity. Curr. Opin. Neurobiol. 9:1999;305-313.
221. Zucker R.S., Fogelson A.L. Relationship between transmitter release and presynaptic calcium influx when calcium enters through discrete channels. Proc. Natl. Acad. Sci. USA. 83:1986;3032-3036.