Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels

EMBO Journal

Volumn 15, Issue 16, 1996, Pages 4100-4110

  Wiser, Ofer ^a   Bennett, Mark K ^b   Atlas, Daphne ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ca2+ channels; SNAP 25; SNAREs; Syntaxin

Indexed keywords

CALCIUM CHANNEL; CELL MEMBRANE PROTEIN; SYNTAXIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE POTENTIAL; ELECTROPHYSIOLOGY; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SYNAPTOSOME;

EID: 0029760302     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00785.x     Document Type: Article

References (40)

1. 2+ channel triggers transmitter release in PC12 cells. FEBS Lett, 342, 209-213.
2. Baumert, M., Maycox, P.R., Navone, F., De Camilli, P. and Jahn, R. (1989) Synaptobrevin: an integral membrane protein of 18000 daltons present in small synaptic vesicles of rat brain. EMBO J., 8, 379-384.
3. Bennett, M.K. and Scheller, R.H. (1993) The molecular machinery for secretion is conserved from yeast to neurons. Proc. Natl Acad. Sci. USA, 90, 2559-2563.
4. Bennett, M.K., Calakos, N. and Scheller, R.H. (1992) Syntaxin, a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science, 257, 255-259.
5. Bennett, M.K., Garcia-Arraras, E., Elferink, L.A., Peterson, K., Fleming, A.M., Hazuka, C.D. and Scheller, R.H. (1993) The syntaxin family of vesicular transport receptors. Cell, 74, 863-873.
6. Bezprozvanny, I., Scheller, R.H. and Tsien, R.W. (1995) Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature, 378, 623-626.
7. Blasi, J., Chapman, E.R., Yamasaki, S., Binz, T., Niemann, H. and Jahn, R. (1993) Botulinum neurotoxin C1 blocks neurotransmitter release by cleavage of HPC-1/syntaxin. EMBO J., 12, 4821-4828.
8. Calakos, N. and Scheller, R.H. (1994) Vesicle associated membrane protein and synaptophysin are associated on the synaptic vesicle. J. Biol. Chem., 269, 24534-24537.
9. Chapman, E.R., An, S., Barton, A.S. and Jahn, R. (1994) SNAP-25, a t-SNARE which bind to both syntaxin and synaptobrevin via domains that may form coiled coils. J. Biol. Chem., 269, 27427-27432.
10. Dubel, S.J., Starr, V.B., Hell, J., Ahlijanian, M.K., Enyeart, J.J., Catterall, W.A. and Snutch, T.P. (1992) Molecular cloning of the α-1 subunit of an ω-conotoxin-sensitive calcium channel. Proc. Natl Acad. Sci. USA, 89, 5058-5062.
11. Ellis, S.B. et al. (1988) Sequence and expression of mRNAs coding the α1 and α2 subunits of the DHP-sensitive calcium channel. Science, 241, 1661-1664.
12. 2+ channel in PC12 cells. Neurosci. Lett., 193, 157-160.
13. Hayashi, T., McMahon, H., Yamasaki, S., Binz, T., Hata, Y., Südhof, T.C. and Niemann, H. (1994) Synaptic membrane fusion complex: action of clostridial neurotoxins on assembly. EMBO J., 13, 5051-5056.
14. Horikawa, P.M.H., Saisu, H., Ishizuka, T., Sekine, Y., Tsugita, A., Odani, S. and Abe, T. (1993) A complex of rab3A, SNAP-25 VAMP/ synaptobrevin-2 and syntaxins in brain presynaptic terminals. FEBS Lett., 330, 236-240.
15. Inoue, A., Obat, K. and Akagawa, K. (1992) Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1. J. Biol. Chem., 267, 10613-10619.
16. Jay, S.D., Sharp, A.H., Kahl, S.D., Vedvick, T.S., Harpold, M.M. and Campbell, K.P (1990) Structural characterization of the dihydropyridine-sensitive calcium channel α2-subunit and the associated δ peptides. J. Biol. Chem., 266, 3287-3293.
17. Kushima, Y., Fujiwara, T., Morimoto, T. and Akagawa, K. (1995) Involvement of HPC-1/syntaxin 1A antigen in transmitter release from PC12h cells. Biochem. Biophys. Res. Commun., 212, 97-103.
18. Lévéque, C. et al. (1992) The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen. Proc. Natl Acad. Sci. USA, 89, 3625-3629.
19. Lévéque, C., El Far, O., Martin-Moutot, N., Sato, K., Kato, R., Takahashi, R. and Seagar, M.J. (1994) Purification of the N-type calcium channel associated with syntaxin and synaptotagmin. A complex implicated in synaptic vesicle exocytosis. J. Biol. Chem., 269, 6306-6312.
20. McMahon, H., Ushkaryov, Y.A., Edelmann, L., Link, E., Binz, T., Niemann, H., Jahn, R. and Südhof, T.S. (1993) Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein. Nature, 364, 346-349.
21. 2+ channel activity. Neuroscience, 65, 905-915.
22. Morita, T. et al. (1992) Synaptocalin I, a protein associated with brain ω-conotoxin-sensitive calcium channels. Biomed. Res., 13, 357-364.
23. Niemann, H., Blasi, J. and Jahn, R. (1994) Clostridial neurotoxins. Trends Cell Biol, 4, 179-185.
24. Olivera, B.M., Miljanich, G.P., Ramachandran, J. and Adams, M.E. (1994) Calcium channel diversity and neurotransmitter release: the ω-conotoxins and ω-agatoxins. Annu. Rev. Biochem., 63, 823-867.
25. Perez-Reyes, E., Castellano, A., Kim, H.S., Bertrand, P., Baggstrom, E., Lacerda, A.E., Wei, X.Y. and Bimbaumer, L. (1992) Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J. Biol. Chem., 267, 1792-1797.
26. Pevsner, J., Hsu, S.C., Braun, J.E.A., Calakos, N., Ting, E., Bennett, M.K. and Scheller, R.H. (1994) Specificity and regulation of a synaptic vesicle docking complex. Neuron, 13, 353-361.
27. Saisu, H., Ibaraki, K., Yamaguchi, T., Sekine, Y. and Abe, T. (1991) Monoclonal antibodies immunoprecipitating ω-conotoxin-sensitive calcium channel molecules recognize two novel proteins localized in the nervous system. Biochem. Biophys. Res. Commun., 181, 346-350.
28. Schreibmayer, W., Lester, H.A. and Dascal, N. (1994) Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes. Pflügers Arch., 426, 453-458.
29. Schiavo, G., Shone, C.C., Bennett, M.K., Scheller, R.H. and Montecucco, C. (1995) Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. J. Biol. Chem., 270, 10566-10570.
30. Sheng, Zu-H., Retting, J., Takahashi, M. and Catterall, W.A. (1994) Identification of a syntaxin-binding site on N-type calcium channels. Neuron, 13, 1303-1313.
31. Sheng, Zu-H., Retting, J., Cook, T. and Catterall, W.A. (1996) Calcium-dependent interaction of N-type calcium channels with the synaptic core complex. Nature, 379, 451-454.
32. Smirnova, T., Fossier, P., Stinnakre, J., Mallet, J., and Baux, G. (1995) A syntaxin related protein controls acetylcholine release by different mechanisms in Aplysia. Neuroscience, 68, 3571-3528.
33. Söllner, T., Whitheart, S.W., Brunner, M., Erdjumenl-Bromage, H., Geromanos, S., Tempest, P. and Rothman, J.A. (1993a) SNAP receptors implicated in vesicle. Nature, 362, 318-323.
34. Söllner, T., Bennett, M.K., Whitheart, S.W., Scheller, R.H. and Rothman, J. (1993b) A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking activation, and fusion. Cell, 75, 409-416.
35. Trimble, W.S., Cowan, D.M. and Scheller, R.H. (1988) VAMP-1: a synaptic vesicle-associated integral membrane protein. Proc. Natl Acad. Sci. USA, 85, 4538-4542.
36. 2+ channels. J. Biol. Chem., 266, 21943-21947.
37. 2+ channel activity by deletions at the carboxyl terminus of the cardiac α1 subunit. J. Biol. Chem., 269, 1635-1640.
38. 2+ channel α1 subunit. Biophys. J., 66, A128.
39. 2+ channels is a single transmembrane extracellular protein which is involved in regulated secretion. FEBS Lett., 379, 15-20.
40. Yoshida, A., Oho, C., Omori, A., Kuwahara, R., Ito, T. and Takahashi, M. (1992) HPC-1 is associated with synaptotagmin and omega-conotoxin receptor. J. Biol. Chem., 267, 24295-24928.