-
1
-
-
0033578406
-
Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1
-
Alani R.M., Hasskarl J., Grace M., Hernandez M.C., Israel M.A., Munger K. Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1. Proc. Natl. Acad. Sci. USA. 96:1999;9637-9641.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9637-9641
-
-
Alani, R.M.1
Hasskarl, J.2
Grace, M.3
Hernandez, M.C.4
Israel, M.A.5
Munger, K.6
-
2
-
-
0034933793
-
Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a
-
Alani R.M., Young A.Z., Shifflett C.B. Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a. Proc. Natl. Acad. Sci. USA. 98:2001;7812-7816.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7812-7816
-
-
Alani, R.M.1
Young, A.Z.2
Shifflett, C.B.3
-
3
-
-
0030791113
-
Involvement of p53 in cell differentiation and development
-
Almog N., Rotter V. Involvement of p53 in cell differentiation and development. Biochim. Biophys. Acta. 1333:1997;F1-F27.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
-
-
Almog, N.1
Rotter, V.2
-
4
-
-
0029052185
-
Promotion of N-nitrosodimethylamine-initiated mouse lung tumors following single or multiple low dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Beebe L.E., Anver M.R., Riggs C.W., Fornwald L.W., Anderson L.M. Promotion of N-nitrosodimethylamine-initiated mouse lung tumors following single or multiple low dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Carcinogenesis. 16:1995;1345-1349.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1345-1349
-
-
Beebe, L.E.1
Anver, M.R.2
Riggs, C.W.3
Fornwald, L.W.4
Anderson, L.M.5
-
5
-
-
0034069237
-
Cancer, aging and cellular senescence
-
Campisi J. Cancer, aging and cellular senescence. In Vivo. 14:2000;183-188.
-
(2000)
In Vivo
, vol.14
, pp. 183-188
-
-
Campisi, J.1
-
6
-
-
0034704848
-
P16 INK4a can initiate an autonomous senescence program
-
Dai C.Y., Enders G.H. p16 INK4a can initiate an autonomous senescence program. Oncogene. 19:2000;1613-1622.
-
(2000)
Oncogene
, vol.19
, pp. 1613-1622
-
-
Dai, C.Y.1
Enders, G.H.2
-
7
-
-
0033979731
-
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
-
Dickson M.A., Hahn W.C., Ino Y., Ronfard V., Wu J.Y., Weinberg R.A., Louis D.N., Li F.P., Rheinwald J.G. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol. Cell. Biol. 20:2000;1436-1447.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1436-1447
-
-
Dickson, M.A.1
Hahn, W.C.2
Ino, Y.3
Ronfard, V.4
Wu, J.Y.5
Weinberg, R.A.6
Louis, D.N.7
Li, F.P.8
Rheinwald, J.G.9
-
8
-
-
0033989829
-
Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor
-
Dimri G.P., Itahana K., Acosta M., Campisi J. Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor. Mol. Cell. Biol. 20:2000;273-285.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 273-285
-
-
Dimri, G.P.1
Itahana, K.2
Acosta, M.3
Campisi, J.4
-
9
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA. 92:1995;9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
10
-
-
0030697433
-
Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Dong L., Ma Q., Whitlock J.P. Jr. Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 272:1997;29614-29619.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29614-29619
-
-
Dong, L.1
Ma, Q.2
Whitlock J.P., Jr.3
-
11
-
-
0030935565
-
The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation
-
Eckert R.L., Crish J.F., Robinson N.A. The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Physiol. Rev. 77:1997;397-424.
-
(1997)
Physiol. Rev.
, vol.77
, pp. 397-424
-
-
Eckert, R.L.1
Crish, J.F.2
Robinson, N.A.3
-
12
-
-
0035065262
-
Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein
-
Elferink C.J., Ge N.L., Levine A. Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Mol. Pharmacol. 59:2001;664-673.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 664-673
-
-
Elferink, C.J.1
Ge, N.L.2
Levine, A.3
-
13
-
-
0034099303
-
Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast
-
Elizondo G., Fernandez-Salguero P., Sheikh M.S., Kim G.Y., Fornace A.J., Lee K.S., Gonzalez F.J. Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast. Mol. Pharmacol. 57:2000;1056-1063.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 1056-1063
-
-
Elizondo, G.1
Fernandez-Salguero, P.2
Sheikh, M.S.3
Kim, G.Y.4
Fornace, A.J.5
Lee, K.S.6
Gonzalez, F.J.7
-
14
-
-
0037068312
-
CpG hypermethylation and tumor suppressor genes: A booming present, a brighter future
-
Esteller M. CpG hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene. 21:2002;5427-5440.
-
(2002)
Oncogene
, vol.21
, pp. 5427-5440
-
-
Esteller, M.1
-
15
-
-
0035297539
-
P14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2
-
Esteller M., Cordon-Cardo C., Corn P.G., Meltzer S.J., Pohar K.S., Watkins D.N., Capella G., Peinado M.A., Matias-Guiu X., Prat J., Baylin S.B., Herman J.G. p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2. Cancer Res. 61:2001;2816-2821.
-
(2001)
Cancer Res.
, vol.61
, pp. 2816-2821
-
-
Esteller, M.1
Cordon-Cardo, C.2
Corn, P.G.3
Meltzer, S.J.4
Pohar, K.S.5
Watkins, D.N.6
Capella, G.7
Peinado, M.A.8
Matias-Guiu, X.9
Prat, J.10
Baylin, S.B.11
Herman, J.G.12
-
16
-
-
20644437756
-
Intestinal cell differentiation: Cellular mechanisms and the search for the perfect model focus on "involvement of p21(WAF1/Cip1) and p27(Kip1) in intestinal epithelial cell differentiation"
-
Evers B.M. Intestinal cell differentiation cellular mechanisms and the search for the perfect model focus on "involvement of p21(WAF1/Cip1) and p27(Kip1) in intestinal epithelial cell differentiation" Am. J. Physiol. 276:(6 Pt1):1999;C1243-C1244.
-
(1999)
Am. J. Physiol.
, vol.276
, Issue.6 PART
-
-
Evers, B.M.1
-
17
-
-
0037468575
-
P14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice
-
Eymin B., Leduc C., Coll J.L., Brambilla E., Gazzeri S. p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice. Oncogene. 22:2003;1822-1835.
-
(2003)
Oncogene
, vol.22
, pp. 1822-1835
-
-
Eymin, B.1
Leduc, C.2
Coll, J.L.3
Brambilla, E.4
Gazzeri, S.5
-
19
-
-
0028023138
-
Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Gaido K.W., Maness S.C. Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 127:1994;199-208.
-
(1994)
Toxicol. Appl. Pharmacol.
, vol.127
, pp. 199-208
-
-
Gaido, K.W.1
Maness, S.C.2
-
20
-
-
0032575589
-
A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle
-
Ge N.L., Elferink C.J. A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J. Biol. Chem. 273:1998;22708-22713.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22708-22713
-
-
Ge, N.L.1
Elferink, C.J.2
-
21
-
-
0022398768
-
Actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on human epidermal keratinocytes in culture
-
Greenlee W.F., Dold K.M., Osborne R. Actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on human epidermal keratinocytes in culture. In Vitro Cell. Dev. Biol. 21:1985;509-512.
-
(1985)
In Vitro Cell. Dev. Biol.
, vol.21
, pp. 509-512
-
-
Greenlee, W.F.1
Dold, K.M.2
Osborne, R.3
-
22
-
-
0028987872
-
The aryl hydrocarbon receptor complex
-
Hankinson O. The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35:1995;307-340.
-
(1995)
Annu. Rev. Pharmacol. Toxicol.
, vol.35
, pp. 307-340
-
-
Hankinson, O.1
-
23
-
-
0033924399
-
Retinoids in chemoprevention and differentiation therapy
-
Hansen L.A., Sigman C.C., Andreola F., Ross S.A., Kelloff G.J., De Luca L.M. Retinoids in chemoprevention and differentiation therapy. Carcinogenesis. 21:2000;1271-1279.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1271-1279
-
-
Hansen, L.A.1
Sigman, C.C.2
Andreola, F.3
Ross, S.A.4
Kelloff, G.J.5
De Luca, L.M.6
-
24
-
-
0029670840
-
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
-
Hara E., Smith R., Parry D., Tahara H., Stone S., Peters G. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol. 16:1996;859-867.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 859-867
-
-
Hara, E.1
Smith, R.2
Parry, D.3
Tahara, H.4
Stone, S.5
Peters, G.6
-
26
-
-
0031750613
-
Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation
-
Harvat B.L., Wang A., Seth P., Jetten A.M. Up-regulation of p27Kip1, p21WAF1/Cip1 and p16Ink4a is associated with, but not sufficient for, induction of squamous differentiation. J. Cell. Sci. 111:(Pt 9):1998;1185-1196.
-
(1998)
J. Cell. Sci.
, vol.111
, Issue.9 PART
, pp. 1185-1196
-
-
Harvat, B.L.1
Wang, A.2
Seth, P.3
Jetten, A.M.4
-
27
-
-
0025243587
-
Role of transforming growth factor beta in the proliferative effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on human squamous carcinoma cells
-
Hebert C.D., Cao Q.L., Birnbaum L.S. Role of transforming growth factor beta in the proliferative effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on human squamous carcinoma cells. Cancer Res. 50:1990;7190-7197.
-
(1990)
Cancer Res.
, vol.50
, pp. 7190-7197
-
-
Hebert, C.D.1
Cao, Q.L.2
Birnbaum, L.S.3
-
28
-
-
0028845142
-
Interactivation of the CDKN2/p16MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman J.G., Merlo A., Mao L., Lapidus R.G., Issa J.P., Davidson N.E., Sidransky D., Baylin S.B. Interactivation of the CDKN2/p16MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 55:1995;4525-4530.
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
29
-
-
0035047512
-
Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice
-
Hosoya T., Oda Y., Takahashi S., Morita M., Kawauchi S., Ema M., Yamamoto M., Fujii-Kuriyama Y. Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice. Genes Cells. 6:2001;361-374.
-
(2001)
Genes Cells
, vol.6
, pp. 361-374
-
-
Hosoya, T.1
Oda, Y.2
Takahashi, S.3
Morita, M.4
Kawauchi, S.5
Ema, M.6
Yamamoto, M.7
Fujii-Kuriyama, Y.8
-
30
-
-
0022644237
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) modulates epidermal growth factor (EGF) binding to basal cells from a human keratinocyte cell line
-
Hudson L.G., Toscano W.A. Jr., Greenlee W.F. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) modulates epidermal growth factor (EGF) binding to basal cells from a human keratinocyte cell line. Toxicol. Appl. Pharma. 82:1986;481-492.
-
(1986)
Toxicol. Appl. Pharma.
, vol.82
, pp. 481-492
-
-
Hudson, L.G.1
Toscano W.A., Jr.2
Greenlee, W.F.3
-
31
-
-
0033049828
-
P16(INK4a) and the control of cellular proliferative life span
-
Huschtscha L.I., Reddel R.R. p16(INK4a) and the control of cellular proliferative life span. Carcinogenesis. 20:1999;921-926.
-
(1999)
Carcinogenesis
, vol.20
, pp. 921-926
-
-
Huschtscha, L.I.1
Reddel, R.R.2
-
32
-
-
0033927808
-
Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes: Involvement of p53 accumulation via ARF-mediated MDM2 down-regulation
-
Itoshima T., Fujiwara T., Waku T., Shao J., Kataoka M., Yarbrough W.G., Liu T.J., Roth J.A., Tanaka N., Kodama M. Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes involvement of p53 accumulation via ARF-mediated MDM2 down-regulation . Clin. Cancer Res. 6:2000;2851-2859.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2851-2859
-
-
Itoshima, T.1
Fujiwara, T.2
Waku, T.3
Shao, J.4
Kataoka, M.5
Yarbrough, W.G.6
Liu, T.J.7
Roth, J.A.8
Tanaka, N.9
Kodama, M.10
-
33
-
-
0029094704
-
Cell cycle arrest and inhibition of tumor cell proliferation by the p16INK4 gene mediated by an adenovirus vector
-
Jin X., Nguyen D., Zhang W.W., Kyritsis A.P., Roth J.A. Cell cycle arrest and inhibition of tumor cell proliferation by the p16INK4 gene mediated by an adenovirus vector. Cancer Res. 55:1995;3250-3253.
-
(1995)
Cancer Res.
, vol.55
, pp. 3250-3253
-
-
Jin, X.1
Nguyen, D.2
Zhang, W.W.3
Kyritsis, A.P.4
Roth, J.A.5
-
35
-
-
0032487675
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono T., Foster S.A., Koop J.I., McDougall J.K., Galloway D.A., Klingelhutz A.J. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature. 396:1998;84-88.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
36
-
-
0033166447
-
P27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells
-
Kolluri S.K., Weiss C., Koff A., Gottlicher M. p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. Genes Dev. 13:1999;1742-1753.
-
(1999)
Genes Dev.
, vol.13
, pp. 1742-1753
-
-
Kolluri, S.K.1
Weiss, C.2
Koff, A.3
Gottlicher, M.4
-
37
-
-
0033816193
-
Concurrence of replicative senescence and elevated expression of p16(INK4A) with subculture-induced but not calcium-induced differentiation in normal human oral keratinocytes
-
Lee G., Park B.S., Han S.E., Oh J.E., You Y.O., Baek J.H., Kim G.S., Min B.M. Concurrence of replicative senescence and elevated expression of p16(INK4A) with subculture-induced but not calcium-induced differentiation in normal human oral keratinocytes. Arch. Oral Biol. 45:2000;809-818.
-
(2000)
Arch. Oral Biol.
, vol.45
, pp. 809-818
-
-
Lee, G.1
Park, B.S.2
Han, S.E.3
Oh, J.E.4
You, Y.O.5
Baek, J.H.6
Kim, G.S.7
Min, B.M.8
-
38
-
-
0034682469
-
Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53
-
Lee S.W., Fang L., Igarashi M., Ouchi T., Lu K.P., Aaronson S.A. Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53. Proc. Natl. Acad. Sci. USA. 97:2000;8302-8305.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8302-8305
-
-
Lee, S.W.1
Fang, L.2
Igarashi, M.3
Ouchi, T.4
Lu, K.P.5
Aaronson, S.A.6
-
39
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
40
-
-
0344301900
-
Role of the p16 tumor suppressor gene in cancer
-
Liggett W.H.J., Sidransky D. Role of the p16 tumor suppressor gene in cancer. J. Clin. Oncol. 16:1998;1197-1206.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1197-1206
-
-
Liggett, W.H.J.1
Sidransky, D.2
-
41
-
-
0036667369
-
In utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin causes accelerated terminal differentiation in fetal mouse skin
-
Loertscher J.A., Lin T.M., Peterson R.E., Allen-Hoffmann B.L. In utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin causes accelerated terminal differentiation in fetal mouse skin. Toxicol. Sci. 68:2002;465-472.
-
(2002)
Toxicol. Sci.
, vol.68
, pp. 465-472
-
-
Loertscher, J.A.1
Lin, T.M.2
Peterson, R.E.3
Allen-Hoffmann, B.L.4
-
42
-
-
0035449670
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation pattern of human keratinocytes in organotypic culture
-
Loertscher J.A., Sattler C.A., Allen-Hoffmann B.L. 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation pattern of human keratinocytes in organotypic culture. Toxicol. Appl. Pharma. 175:2001;121-129.
-
(2001)
Toxicol. Appl. Pharma.
, vol.175
, pp. 121-129
-
-
Loertscher, J.A.1
Sattler, C.A.2
Allen-Hoffmann, B.L.3
-
44
-
-
0021244987
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces hyperplasia in confluent cultures of human keratinocytes
-
Milstone L.M., LaVigne J.F. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces hyperplasia in confluent cultures of human keratinocytes. J. Invest. Dermatol. 82:1984;532-534.
-
(1984)
J. Invest. Dermatol.
, vol.82
, pp. 532-534
-
-
Milstone, L.M.1
LaVigne, J.F.2
-
45
-
-
0032947853
-
Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)
-
Mitra J., Dai C.Y., Somasundaram K., El-Deiry W.S., Satyamoorthy K., Herlyn M., Enders G.H. Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a). Mol. Cell. Biol. 19:1999;3916-3928.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3916-3928
-
-
Mitra, J.1
Dai, C.Y.2
Somasundaram, K.3
El-Deiry, W.S.4
Satyamoorthy, K.5
Herlyn, M.6
Enders, G.H.7
-
46
-
-
0033152226
-
Role of the alternative INK4A proteins in human keratinocyte senescence: Evidence for the specific inactivation of p16INK4A upon immortalization
-
Munro J., Stott F.J., Vousden K.H., Peters G., Parkinson E.K. Role of the alternative INK4A proteins in human keratinocyte senescence evidence for the specific inactivation of p16INK4A upon immortalization . Cancer Res. 59:1999;2516-2521.
-
(1999)
Cancer Res.
, vol.59
, pp. 2516-2521
-
-
Munro, J.1
Stott, F.J.2
Vousden, K.H.3
Peters, G.4
Parkinson, E.K.5
-
47
-
-
0034623229
-
Id-1 delays senescence but does not immortalize keratinocytes
-
Nickoloff B.J., Chaturvedi V., Bacon P., Qin J.Z., Denning M.F., Diaz M.O. Id-1 delays senescence but does not immortalize keratinocytes. J. Biol. Chem. 275:2000;27501-27504.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27501-27504
-
-
Nickoloff, B.J.1
Chaturvedi, V.2
Bacon, P.3
Qin, J.Z.4
Denning, M.F.5
Diaz, M.O.6
-
49
-
-
0031043421
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCCD) affects keratin 1 and keratin 17 gene expression and differentially induces keratinization in hairless mouse skin
-
Panteleyev A.A., Thiel R., Wanner R., Zhang J., Roumak V.S., Paus R., Neubert D., Henz B.M., Rosenbach T. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCCD) affects keratin 1 and keratin 17 gene expression and differentially induces keratinization in hairless mouse skin. J. Invest. Dermatol. 108:1997;330-335.
-
(1997)
J. Invest. Dermatol.
, vol.108
, pp. 330-335
-
-
Panteleyev, A.A.1
Thiel, R.2
Wanner, R.3
Zhang, J.4
Roumak, V.S.5
Paus, R.6
Neubert, D.7
Henz, B.M.8
Rosenbach, T.9
-
50
-
-
0036594830
-
Hsp25 regulates the expression of p21(Waf1/Cip1/Sdi1) through multiple mechanisms
-
Park S.H., Lee Y.S., Osawa Y., Hachiya M., Akashi M. Hsp25 regulates the expression of p21(Waf1/Cip1/Sdi1) through multiple mechanisms. J. Biochem. (Tokyo). 131:2002;869-875.
-
(2002)
J. Biochem. (Tokyo)
, vol.131
, pp. 869-875
-
-
Park, S.H.1
Lee, Y.S.2
Osawa, Y.3
Hachiya, M.4
Akashi, M.5
-
51
-
-
0018932459
-
Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine
-
Pitot H.C., Goldsworthy T., Campbel H.A., Poland A. Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine. Cancer Res. 40:1980;3616-3620.
-
(1980)
Cancer Res.
, vol.40
, pp. 3616-3620
-
-
Pitot, H.C.1
Goldsworthy, T.2
Campbel, H.A.3
Poland, A.4
-
52
-
-
0020010617
-
2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
-
Poland A., Knutson J.C. 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons examination of the mechanism of toxicity . Annu. Rev. Pharmacol. Toxicol. 22:1982;517-554.
-
(1982)
Annu. Rev. Pharmacol. Toxicol.
, vol.22
, pp. 517-554
-
-
Poland, A.1
Knutson, J.C.2
-
53
-
-
0020425524
-
Tumour promotion by TCDD in skin of HRS/J hairless mice
-
Poland A., Palen D., Glover E. Tumour promotion by TCDD in skin of HRS/J hairless mice. Nature. 300:1982;271-273.
-
(1982)
Nature
, vol.300
, pp. 271-273
-
-
Poland, A.1
Palen, D.2
Glover, E.3
-
54
-
-
0037145007
-
The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation
-
Pollenz R. The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation. Chem. Biol. Interact. 141:2002;41.
-
(2002)
Chem. Biol. Interact.
, vol.141
, pp. 41
-
-
Pollenz, R.1
-
55
-
-
0035881619
-
The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas
-
Polsky D., Young A.Z., Busam K.J., Alani R.M. The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas. Cancer Res. 61:2001;6008-6011.
-
(2001)
Cancer Res.
, vol.61
, pp. 6008-6011
-
-
Polsky, D.1
Young, A.Z.2
Busam, K.J.3
Alani, R.M.4
-
56
-
-
0034723264
-
Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest
-
Puga A., Barnes S.J., Dalton T.P., Chang C.Y., Knudsen E.S., Maier M.A. Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J. Biol. Chem. 275:2000;2943-2950.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2943-2950
-
-
Puga, A.1
Barnes, S.J.2
Dalton, T.P.3
Chang, C.Y.4
Knudsen, E.S.5
Maier, M.A.6
-
57
-
-
0031879021
-
Modulation of human epidermal cell response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by epidermal growth factor
-
Rea M.A., Phillips M.A., Degraffenried L.A., Qin Q., Rice R.H. Modulation of human epidermal cell response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by epidermal growth factor. Carcinogenesis. 19:1998;479-483.
-
(1998)
Carcinogenesis
, vol.19
, pp. 479-483
-
-
Rea, M.A.1
Phillips, M.A.2
Degraffenried, L.A.3
Qin, Q.4
Rice, R.H.5
-
58
-
-
9444255067
-
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma
-
Reed A.L., Califano J., Cairns P., Westra W.H., Jones R.M., Koch W., Ahrendt S., Eby Y., Sewell D., Nawroz H., Bartek J., Sidransky D. High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma. Cancer Res. 56:1996;3630-3633.
-
(1996)
Cancer Res.
, vol.56
, pp. 3630-3633
-
-
Reed, A.L.1
Califano, J.2
Cairns, P.3
Westra, W.H.4
Jones, R.M.5
Koch, W.6
Ahrendt, S.7
Eby, Y.8
Sewell, D.9
Nawroz, H.10
Bartek, J.11
Sidransky, D.12
-
59
-
-
0036288508
-
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
-
Rheinwald J.G., Hahn W.C., Ramsey M.R., Wu J.Y., Guo Z., Tsao H., D.e Luca, M., Catricala C., O'Toole K.M. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol. Cell. Biol. 22:2002;5157-5172.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5157-5172
-
-
Rheinwald, J.G.1
Hahn, W.C.2
Ramsey, M.R.3
Wu, J.Y.4
Guo, Z.5
Tsao, H.6
De Luca, M.7
Catricala, C.8
O'Toole, K.M.9
-
60
-
-
0021345330
-
Opposing effects of 2,3,7,8-teraclorodibenzo-p-dioxin and hydrocortisone on growth and differentiation of cultured malignant human keratinocytes
-
Rice R.H., Cline P.R. Opposing effects of 2,3,7,8-teraclorodibenzo-p-dioxin and hydrocortisone on growth and differentiation of cultured malignant human keratinocytes. Carcinogenesis. 5:1984;367-371.
-
(1984)
Carcinogenesis
, vol.5
, pp. 367-371
-
-
Rice, R.H.1
Cline, P.R.2
-
62
-
-
0031035671
-
Differentiation, differentiation/gene therapy and cancer
-
Scott R.E. Differentiation, differentiation/gene therapy and cancer. Pharmacol. Ther. 73:1997;51-65.
-
(1997)
Pharmacol. Ther.
, vol.73
, pp. 51-65
-
-
Scott, R.E.1
-
64
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr C.J., Roberts J.M. CDK inhibitors positive and negative regulators of G1-phase progression . Genes Dev. 13:1999;1501-1512.
-
(1999)
Genes Dev.
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
65
-
-
0036783736
-
Ligand-dependent and independent modulation of aryl hydrocarbon receptor localization, degradation, and gene regulation
-
Song Z., Pollenz R.S. Ligand-dependent and independent modulation of aryl hydrocarbon receptor localization, degradation, and gene regulation. Mol. Pharmacol. 62:2002;806-816.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 806-816
-
-
Song, Z.1
Pollenz, R.S.2
-
66
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott F.J., Bates S., James M.C., McConnell B.B., Starborg M., Brookes S., Palmero I., Ryan K., Hara E., Vousden K.H., Peters G. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17:1998;5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
67
-
-
0021844262
-
Chloracne, "the hallmark of dioxin intoxication"
-
Suskind R.R. Chloracne, "the hallmark of dioxin intoxication" Scand J. Work Environ. Health. 11:(3 Spec No.):1985;165-171.
-
(1985)
Scand J. Work Environ. Health
, vol.11
, Issue.3 SPEC. NO.
, pp. 165-171
-
-
Suskind, R.R.1
-
68
-
-
0028865103
-
DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins
-
Swanson H.I., Chan W.K., Bradfield C.A. DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. J. Biol. Chem. 270:1995;26292-26302.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26292-26302
-
-
Swanson, H.I.1
Chan, W.K.2
Bradfield, C.A.3
-
69
-
-
0034703742
-
P53: Death star
-
Vousden K.H. p53 death star . Cell. 103:2000;691-694.
-
(2000)
Cell
, vol.103
, pp. 691-694
-
-
Vousden, K.H.1
-
70
-
-
85047700405
-
Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways
-
Weber H.O., Samuel T., Rauch P., Funk J.O. Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways. Oncogene. 21:2002;3207-3212.
-
(2002)
Oncogene
, vol.21
, pp. 3207-3212
-
-
Weber, H.O.1
Samuel, T.2
Rauch, P.3
Funk, J.O.4
-
71
-
-
0034813364
-
Role of p14(ARF) in replicative and induced senescence of human fibroblasts
-
Wei W., Hemmer R.M., Sedivy J.M. Role of p14(ARF) in replicative and induced senescence of human fibroblasts. Mol. Cell. Biol. 21:2001;6748-6757.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6748-6757
-
-
Wei, W.1
Hemmer, R.M.2
Sedivy, J.M.3
-
72
-
-
0033535607
-
Caspase activation in the terminal differentiation of human epidermal keratinocytes
-
Weil M., Raff M.C., Braga V.M. Caspase activation in the terminal differentiation of human epidermal keratinocytes. Curr. Biol. 9:1999;361-364.
-
(1999)
Curr. Biol.
, vol.9
, pp. 361-364
-
-
Weil, M.1
Raff, M.C.2
Braga, V.M.3
-
74
-
-
0026643609
-
DNA sequence determinants for binding of transformed Ah receptor to a dioxin-responsive enhancer
-
Yao E.F., Denison M.S. DNA sequence determinants for binding of transformed Ah receptor to a dioxin-responsive enhancer. Biochemistry. 31:1992;5060-5067.
-
(1992)
Biochemistry
, vol.31
, pp. 5060-5067
-
-
Yao, E.F.1
Denison, M.S.2
-
75
-
-
0028351556
-
The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis - Thirty-third G. H. A. Clowes Memorial Award Lecture
-
Yuspa S.H. The pathogenesis of squamous cell cancer lessons learned from studies of skin carcinogenesis - thirty-third G. H. A. Clowes Memorial Award Lecture . Cancer Res. 54:1994;1178-1189.
-
(1994)
Cancer Res.
, vol.54
, pp. 1178-1189
-
-
Yuspa, S.H.1
-
76
-
-
0037452888
-
Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomalloci
-
Zhang H., Pan K.H., Cohen S.N. Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomalloci. Proc. Natl. Acad. Sci. USA. 100:2003;3251-3256.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3251-3256
-
-
Zhang, H.1
Pan, K.H.2
Cohen, S.N.3
-
77
-
-
0036771637
-
Modulation of the expression of p16INK4a and p14ARF by hnRNP A1 and A2 RNA binding proteins: Implications for cellular senescence
-
Zhu D., Xu G., Ghandhi S., Hubbard K. Modulation of the expression of p16INK4a and p14ARF by hnRNP A1 and A2 RNA binding proteins implications for cellular senescence . J. Cell Physiol. 193:2002;19-25.
-
(2002)
J. Cell Physiol.
, vol.193
, pp. 19-25
-
-
Zhu, D.1
Xu, G.2
Ghandhi, S.3
Hubbard, K.4
|