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Volumn 21, Issue 7, 2000, Pages 1271-1279

Retinoids in chemoprevention and differentiation therapy

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; AROMATIC HYDROCARBON RECEPTOR; ARSENIC OXIDE; CYTOCHROME P450; RETINAL; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOL; RETINOL PALMITATE; UNCLASSIFIED DRUG;

EID: 0033924399     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.5.271     Document Type: Review
Times cited : (260)

References (116)
  • 1
    • 0002422384 scopus 로고
    • Plasma retinol binding protein
    • Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) Academic Press, Orlando, FL
    • Goodman, D.S. (1984) Plasma retinol binding protein. In Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) The Retinoids. Academic Press, Orlando, FL, Vol. 2, pp. 41-88.
    • (1984) The Retinoids , vol.2 , pp. 41-88
    • Goodman, D.S.1
  • 2
  • 4
    • 0024509538 scopus 로고
    • Comparison of the uptake and metabolism of retinol delivered to primary mouse keratinocytes either free or bound to rat serum retinol-binding protein
    • Creek, K.E., Silverman-Jones, C.S. and De Luca, L.M. (1989) Comparison of the uptake and metabolism of retinol delivered to primary mouse keratinocytes either free or bound to rat serum retinol-binding protein. J. Invest. Dermatol., 92, 283-289.
    • (1989) J. Invest. Dermatol. , vol.92 , pp. 283-289
    • Creek, K.E.1    Silverman-Jones, C.S.2    De Luca, L.M.3
  • 5
    • 0026446319 scopus 로고
    • Characterization of a plasma retinol-binding protein membrane receptor expressed in the retinal pigment epithelium
    • Bavik, C.O., Busch, C. and Eriksson, U. (1992) Characterization of a plasma retinol-binding protein membrane receptor expressed in the retinal pigment epithelium. J. Biol. Chem., 267, 23035-23042.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23035-23042
    • Bavik, C.O.1    Busch, C.2    Eriksson, U.3
  • 6
    • 0003035905 scopus 로고
    • Cellular retinoid-binding proteins
    • Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) Raven Press, New York, NY
    • Ong, D.E., Newcomer, M.E. and Chytil, F. (1994) Cellular retinoid-binding proteins. In Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) The Retinoids: Biology, Chemistry and Medicine, 2nd Edn. Raven Press, New York, NY, pp. 303-304.
    • (1994) The Retinoids: Biology, Chemistry and Medicine, 2nd Edn. , pp. 303-304
    • Ong, D.E.1    Newcomer, M.E.2    Chytil, F.3
  • 7
    • 0027514211 scopus 로고
    • Biosynthesis and metabolism of retinoic acid: Roles of CRBP and CRABP in retinoic acid homeostasis
    • Napoli, J.L. (1993) Biosynthesis and metabolism of retinoic acid: roles of CRBP and CRABP in retinoic acid homeostasis. J. Nutr., 123, 362-366.
    • (1993) J. Nutr. , vol.123 , pp. 362-366
    • Napoli, J.L.1
  • 8
    • 0029839230 scopus 로고    scopus 로고
    • Retinoic acid biosynthesis and metabolism
    • Napoli, J.L. (1996) Retinoic acid biosynthesis and metabolism. FASEB J., 10, 993-1001.
    • (1996) FASEB J. , vol.10 , pp. 993-1001
    • Napoli, J.L.1
  • 9
    • 0002259767 scopus 로고
    • Retinol and retinoic acid metabolism
    • Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) Raven Press, New York, NY
    • Blaner, W.S. and Olson, J.A. (1994) Retinol and retinoic acid metabolism. In Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) The Retinoids: Biology, Chemistry and Medicine, 2nd Edn. Raven Press, New York, NY. pp. 229-255.
    • (1994) The Retinoids: Biology, Chemistry and Medicine, 2nd Edn. , pp. 229-255
    • Blaner, W.S.1    Olson, J.A.2
  • 12
    • 0030850098 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor knockout mice (AHR-/-) exhibit liver retinoid accumulation and reduced retinoic acid metabolism
    • Andreola, F., Fernandez-Salguero, P.M., Chiantore, M.V., Petkovich, M.P., Gonzalez, F.J. and De Luca, L.M. (1997) Aryl hydrocarbon receptor knockout mice (AHR-/-) exhibit liver retinoid accumulation and reduced retinoic acid metabolism. Cancer Res., 57, 2835-2838.
    • (1997) Cancer Res. , vol.57 , pp. 2835-2838
    • Andreola, F.1    Fernandez-Salguero, P.M.2    Chiantore, M.V.3    Petkovich, M.P.4    Gonzalez, F.J.5    De Luca, L.M.6
  • 13
    • 0030746211 scopus 로고    scopus 로고
    • cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450
    • White, J.A., Beckett-Jones, B., Guo, Y.D., Dilworth, F.J., Bonasoro, J., Jones, G. and Petkovich, M. (1997) cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. J. Biol. Chem., 272, 18538-18541.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18538-18541
    • White, J.A.1    Beckett-Jones, B.2    Guo, Y.D.3    Dilworth, F.J.4    Bonasoro, J.5    Jones, G.6    Petkovich, M.7
  • 14
    • 0030872361 scopus 로고    scopus 로고
    • Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos
    • Fujii, H., Sato, T., Kaneko, S., Gotoh, O., Fujii-Kuriyama, Y., Osawa, K., Kato, S. and Hamada, H. (1997) Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos. EMBO J., 16, 4163-4173.
    • (1997) EMBO J. , vol.16 , pp. 4163-4173
    • Fujii, H.1    Sato, T.2    Kaneko, S.3    Gotoh, O.4    Fujii-Kuriyama, Y.5    Osawa, K.6    Kato, S.7    Hamada, H.8
  • 15
    • 0030051022 scopus 로고    scopus 로고
    • Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter
    • Nagy, L., Saydak, M., Shipley, N., Lu, S., Basilion J.P., Yan, Z.H., Syka, P., Chandraratna, R.A., Stein, J.P., Heyman, R.A. and Davies, P.J. (1996) Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. J. Biol. Chem., 271, 4355-4365.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4355-4365
    • Nagy, L.1    Saydak, M.2    Shipley, N.3    Lu, S.4    Basilion, J.P.5    Yan, Z.H.6    Syka, P.7    Chandraratna, R.A.8    Stein, J.P.9    Heyman, R.A.10    Davies, P.J.11
  • 17
    • 84989611379 scopus 로고
    • Tissue changes following deprivation of fat-soluble A-vitamin
    • Wolbach, S.B. and Howe, P.R. (1925) Tissue changes following deprivation of fat-soluble A-vitamin. J. Exp. Med., 42, 753-778.
    • (1925) J. Exp. Med. , vol.42 , pp. 753-778
    • Wolbach, S.B.1    Howe, P.R.2
  • 18
    • 0017136711 scopus 로고
    • Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)
    • Sporn, M.B., Dunlop, N.M., Newton, D.L. and Smith, J.M. (1976) Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed. Proc., 35, 1332-1338.
    • (1976) Fed. Proc. , vol.35 , pp. 1332-1338
    • Sporn, M.B.1    Dunlop, N.M.2    Newton, D.L.3    Smith, J.M.4
  • 19
    • 0026467278 scopus 로고
    • Retinoid status and the control of keratin expression and adhesion during the histogenesis of squamous metaplasia of tracheal epithelium
    • Lancillotti, F., Darwiche, N., Celli, G. and De Luca, L.M. (1992) Retinoid status and the control of keratin expression and adhesion during the histogenesis of squamous metaplasia of tracheal epithelium. Cancer Res., 22, 6144-6152.
    • (1992) Cancer Res. , vol.22 , pp. 6144-6152
    • Lancillotti, F.1    Darwiche, N.2    Celli, G.3    De Luca, L.M.4
  • 20
    • 0030756028 scopus 로고    scopus 로고
    • The role of vitamin A in differentiation and skin carcinogenesis
    • De Luca, L.M., Kosa, K. and Andreola, F. (1997) The role of vitamin A in differentiation and skin carcinogenesis. J. Nutr. Biochem., 8, 426-437.
    • (1997) J. Nutr. Biochem. , vol.8 , pp. 426-437
    • De Luca, L.M.1    Kosa, K.2    Andreola, F.3
  • 21
    • 0027174143 scopus 로고
    • Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium
    • Darwiche, N., Celli, G., Sly, L., Lancillotti, F. and De Luca, L.M. (1993) Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium. Cancer Res., 53, 2287-2299.
    • (1993) Cancer Res. , vol.53 , pp. 2287-2299
    • Darwiche, N.1    Celli, G.2    Sly, L.3    Lancillotti, F.4    De Luca, L.M.5
  • 22
    • 0015992642 scopus 로고
    • Vitamin A deficiency enhances binding of benzo(a)pyrene to tracheal epithelial DNA
    • Genta, V.M., Kaufman, D.G., Harris, C.C., Smith, J.M., Sporn, M.B. and Saffiotti, U. (1974) Vitamin A deficiency enhances binding of benzo(a)pyrene to tracheal epithelial DNA. Nature, 247, 48-49.
    • (1974) Nature , vol.247 , pp. 48-49
    • Genta, V.M.1    Kaufman, D.G.2    Harris, C.C.3    Smith, J.M.4    Sporn, M.B.5    Saffiotti, U.6
  • 23
    • 0343834730 scopus 로고
    • Retinoids in differentiation and tumorigenesis
    • Enwonwu, C. (ed.) Meharry Medical College, Nashville, TN
    • Huang, F.L., Lancillotti, F. and De Luca, L.M. (1991) Retinoids in differentiation and tumorigenesis. In Enwonwu, C. (ed.) Diet, Nutrition and Cancer. Meharry Medical College, Nashville, TN, Vol. IV. pp. 185-201.
    • (1991) Diet, Nutrition and Cancer , vol.4 , pp. 185-201
    • Huang, F.L.1    Lancillotti, F.2    De Luca, L.M.3
  • 24
    • 0003060912 scopus 로고
    • Retinoids and cancer in experimental animals
    • Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) Raven Press. New York, NY
    • Moon, R.C., Mehta, R.G. and Rao, K.V.N. (1994) Retinoids and cancer in experimental animals. In Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds) The Retinoids: Biology, Chemistry and Medicine. Raven Press. New York, NY, pp. 573-595.
    • (1994) The Retinoids: Biology, Chemistry and Medicine , pp. 573-595
    • Moon, R.C.1    Mehta, R.G.2    Rao, K.V.N.3
  • 25
    • 0032704372 scopus 로고    scopus 로고
    • Perspectives on cancer chemoprevention research and drug development
    • Kelloff, G.J. (1999) Perspectives on cancer chemoprevention research and drug development. Adv. Cancer Res., 278, 199-334.
    • (1999) Adv. Cancer Res. , vol.278 , pp. 199-334
    • Kelloff, G.J.1
  • 28
    • 0001833884 scopus 로고
    • Historical developments in vitamin A research
    • De Luca, H.F. (ed.) Plenum, New York, NY
    • De Luca, L.M. (1978) Historical developments in vitamin A research. In De Luca, H.F. (ed.) Fat Soluble Vitamins. Plenum, New York, NY. pp. 1-67.
    • (1978) Fat Soluble Vitamins , pp. 1-67
    • De Luca, L.M.1
  • 31
    • 0008234636 scopus 로고
    • Retinoids and skin cancer
    • Mukhtar, H. (ed.) CRC Press, Boca Raton, FL
    • Chen, L.C. and De Luca, L.M. (1995) Retinoids and skin cancer. In Mukhtar, H. (ed.) Skin Cancer: Mechanisms and Human Relevance. CRC Press, Boca Raton, FL, pp. 401-424.
    • (1995) Skin Cancer: Mechanisms and Human Relevance , pp. 401-424
    • Chen, L.C.1    De Luca, L.M.2
  • 32
    • 0024485404 scopus 로고
    • Consequences of exposure to initiating levels of carcinogens in vitro and in vivo: Altered differentiation and growth, mutations and transformation
    • Slaga, T.J., Klein-Szanto, A.J.P., Boutwell, R.K., Stevenson, D.E., Spitzer, H.L. and D'Motto, B. (eds) Alan R. Liss, New York, NY
    • Yuspa, S.H., Kilkenny, A.E., Roop, D.R., Strickland, J.E., Tucker, R., Hennings, H. and Jaken, S. (1989) Consequences of exposure to initiating levels of carcinogens in vitro and in vivo: altered differentiation and growth, mutations and transformation. In Slaga, T.J., Klein-Szanto, A.J.P., Boutwell, R.K., Stevenson, D.E., Spitzer, H.L. and D'Motto, B. (eds) Skin Carcinogenesis: Mechanisms and Human Relevance. Alan R. Liss, New York, NY, pp. 127-135.
    • (1989) Skin Carcinogenesis: Mechanisms and Human Relevance , pp. 127-135
    • Yuspa, S.H.1    Kilkenny, A.E.2    Roop, D.R.3    Strickland, J.E.4    Tucker, R.5    Hennings, H.6    Jaken, S.7
  • 33
    • 0029125341 scopus 로고
    • High dietary retinoic acid inhibits tumor promotion and malignant conversion in a two-stage skin carcinogenesis protocol using 7,12-dimethylbenz(a)-anthracene as the initiator and mezerein as the tumor promoter in female SENCAR mice
    • Chen, L.C., Tarone, R., Huynh, M. and De Luca, L.M. (1995) High dietary retinoic acid inhibits tumor promotion and malignant conversion in a two-stage skin carcinogenesis protocol using 7,12-dimethylbenz(a)-anthracene as the initiator and mezerein as the tumor promoter in female SENCAR mice. Cancer Lett., 95, 113-118.
    • (1995) Cancer Lett. , vol.95 , pp. 113-118
    • Chen, L.C.1    Tarone, R.2    Huynh, M.3    De Luca, L.M.4
  • 34
    • 0028143187 scopus 로고
    • High dietary retinoic acid prevents malignant conversion of skin papillomas induced by a two-stage carcinogenesis protocol in female SENCAR mice
    • Chen, L.C., Sly, L. and De Luca, L.M. (1994) High dietary retinoic acid prevents malignant conversion of skin papillomas induced by a two-stage carcinogenesis protocol in female SENCAR mice. Carcinogenesis, 15, 2383-2386.
    • (1994) Carcinogenesis , vol.15 , pp. 2383-2386
    • Chen, L.C.1    Sly, L.2    De Luca, L.M.3
  • 36
    • 0029058519 scopus 로고
    • Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors
    • Darwiche, N., Celli, G., Tennenbaum, T., Glick, A.B., Yuspa, S.H. and De Luca, L.M. (1995) Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors. Cancer Res., 55, 2774-2782.
    • (1995) Cancer Res. , vol.55 , pp. 2774-2782
    • Darwiche, N.1    Celli, G.2    Tennenbaum, T.3    Glick, A.B.4    Yuspa, S.H.5    De Luca, L.M.6
  • 37
    • 0028796740 scopus 로고
    • Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR β2/ RARE (DR5)
    • Xiao, J.H., Durand, B., Chambon, P. and Voorhees, J.J. (1995) Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR β2/ RARE (DR5). J. Biol. Chern., 270, 3001-3011.
    • (1995) J. Biol. Chern. , vol.270 , pp. 3001-3011
    • Xiao, J.H.1    Durand, B.2    Chambon, P.3    Voorhees, J.J.4
  • 39
    • 0029818411 scopus 로고    scopus 로고
    • Retinoids and their receptors in modulation of differentiation, development and prevention of head and neck cancers
    • Lotan, R. (1996) Retinoids and their receptors in modulation of differentiation, development and prevention of head and neck cancers. Anticancer Res., 16, 2415-2419.
    • (1996) Anticancer Res. , vol.16 , pp. 2415-2419
    • Lotan, R.1
  • 40
    • 0029796637 scopus 로고    scopus 로고
    • Retinoids in cancer chemoprevention
    • Lotan, R. (1996) Retinoids in cancer chemoprevention. FASEB J., 10, 1031-1039.
    • (1996) FASEB J. , vol.10 , pp. 1031-1039
    • Lotan, R.1
  • 41
    • 0031037427 scopus 로고    scopus 로고
    • Molecular epidemiology and retinoid chemoprevention of head and neck cancer
    • Khuri, F.R., Lippman, S.M., Spitz, M.R., Lotan, R. and Hong, W.K. (1997) Molecular epidemiology and retinoid chemoprevention of head and neck cancer. J. Natl Cancer Inst., 89, 199-211.
    • (1997) J. Natl Cancer Inst. , vol.89 , pp. 199-211
    • Khuri, F.R.1    Lippman, S.M.2    Spitz, M.R.3    Lotan, R.4    Hong, W.K.5
  • 43
    • 0031460554 scopus 로고    scopus 로고
    • Dietary retinoids andcarotenoids in rodent models of mammary tumorigenesis
    • Moon, R.C. and Constantinou, A.I. (1997) Dietary retinoids andcarotenoids in rodent models of mammary tumorigenesis. Breast Cancer Res. Treat., 46, 181-189.
    • (1997) Breast Cancer Res. Treat. , vol.46 , pp. 181-189
    • Moon, R.C.1    Constantinou, A.I.2
  • 45
    • 0022973551 scopus 로고
    • N-(4-hydroxyphenyl)-all-trans-retinamide pharmacokinetics in female rats and mice
    • Hultin, T.A., May, C.M. and Moon,R.C. (1986) N-(4-hydroxyphenyl)-all-trans-retinamide pharmacokinetics in female rats and mice. Drug Metab. Dispos., 14, 714-717.
    • (1986) Drug Metab. Dispos. , vol.14 , pp. 714-717
    • Hultin, T.A.1    May, C.M.2    Moon, R.C.3
  • 46
    • 0024238354 scopus 로고
    • Metabolism of the chemopreventive retinoid N-(4-hydroxyphenyl)retinamide by mammary gland in organ culture
    • Mehta, R.G., Hultin, T.A. and Moon, R.C. (1988) Metabolism of the chemopreventive retinoid N-(4-hydroxyphenyl)retinamide by mammary gland in organ culture. Biochem. J., 256, 579-584.
    • (1988) Biochem. J. , vol.256 , pp. 579-584
    • Mehta, R.G.1    Hultin, T.A.2    Moon, R.C.3
  • 47
    • 0026018908 scopus 로고
    • Distribution of fenretinide in the mammary gland of breast cancer patients
    • Mehta, R.G., Moon, R.C., Hawthorne, M., Formelli, F. and Costa, A. (1991) Distribution of fenretinide in the mammary gland of breast cancer patients. Eur. J. Cancer. 27, 138-141.
    • (1991) Eur. J. Cancer. , vol.27 , pp. 138-141
    • Mehta, R.G.1    Moon, R.C.2    Hawthorne, M.3    Formelli, F.4    Costa, A.5
  • 49
    • 0028206734 scopus 로고
    • Prospects of chemoprevention of human cancers with the synthetic retinoid renretinide
    • Costa, A., Formelli, F., Chiesa, F., Decensi, A., De Palo, G. and Veronesi, U. (1994) Prospects of chemoprevention of human cancers with the synthetic retinoid renretinide. Cancer Res., 54, 2032s-2037s.
    • (1994) Cancer Res. , vol.54
    • Costa, A.1    Formelli, F.2    Chiesa, F.3    Decensi, A.4    De Palo, G.5    Veronesi, U.6
  • 52
    • 0028608987 scopus 로고
    • Vitamin A, retinoids and breast cancer
    • Moon, R.C. (1994) Vitamin A, retinoids and breast cancer. Adv. Exp. Med. Biol., 364, 101-107.
    • (1994) Adv. Exp. Med. Biol. , vol.364 , pp. 101-107
    • Moon, R.C.1
  • 55
    • 0027982042 scopus 로고
    • Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen
    • Anzano, M.A., Byers, S.W., Smith, J.M., Peer, C.W., Mullen, L.T., Brown, C.C., Roberts, A.B. and Sporn, M.B. (1994) Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen. Cancer Res., 54, 4614-4617.
    • (1994) Cancer Res. , vol.54 , pp. 4614-4617
    • Anzano, M.A.1    Byers, S.W.2    Smith, J.M.3    Peer, C.W.4    Mullen, L.T.5    Brown, C.C.6    Roberts, A.B.7    Sporn, M.B.8
  • 56
    • 0032006028 scopus 로고    scopus 로고
    • Beyond tamoxifen: The retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma
    • Bischoff, E.D., Gottardis, M.M., Moon, T.E., Heyman, R.A. and Lamph, W.W. (1998) Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma. Cancer Res., 58, 479-484.
    • (1998) Cancer Res. , vol.58 , pp. 479-484
    • Bischoff, E.D.1    Gottardis, M.M.2    Moon, T.E.3    Heyman, R.A.4    Lamph, W.W.5
  • 57
    • 0019743777 scopus 로고
    • Retinoid binding in normal and neoplastic mammary tissue
    • Leavitt, W.W. (ed.) Plenum Press, New York, NY
    • Moon, R.C. and Mehta, R.G. (1982) Retinoid binding in normal and neoplastic mammary tissue. In Leavitt, W.W. (ed.) Hormones and Cancer. Plenum Press, New York, NY, pp. 231-249.
    • (1982) Hormones and Cancer , pp. 231-249
    • Moon, R.C.1    Mehta, R.G.2
  • 58
    • 0020071911 scopus 로고
    • Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy
    • McCormick, D.L., Mehta, R.G., Thompson, C.A., Dinger, N., Caldwell, J.A. and Moon, R.C. (1982) Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy. Cancer Res., 42, 508-512.
    • (1982) Cancer Res. , vol.42 , pp. 508-512
    • McCormick, D.L.1    Mehta, R.G.2    Thompson, C.A.3    Dinger, N.4    Caldwell, J.A.5    Moon, R.C.6
  • 59
    • 0024321412 scopus 로고
    • Chemopreventive efficacy of combined retinoid and tamoxifen treatment following surgical excision of a primary mammary cancer in female rats
    • Ratko, T.A., Detrisac, C.J., Dinger, N.M., Thomas, C.F., Kelloff, G.J. and Moon, R.C. (1989) Chemopreventive efficacy of combined retinoid and tamoxifen treatment following surgical excision of a primary mammary cancer in female rats. Cancer Res., 49, 4472-4476.
    • (1989) Cancer Res. , vol.49 , pp. 4472-4476
    • Ratko, T.A.1    Detrisac, C.J.2    Dinger, N.M.3    Thomas, C.F.4    Kelloff, G.J.5    Moon, R.C.6
  • 61
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Hong, W.K. and Sporn, M.B. (1997) Recent advances in chemoprevention of cancer. Science, 278, 1073-1077.
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 62
    • 0023125497 scopus 로고
    • Acute promyelocytic leukemia. A childhood cluster
    • Gilbert, R.D., Karabus, C.D. and Mills, A.E. (1987) Acute promyelocytic leukemia. A childhood cluster. Cancer, 59, 933-935.
    • (1987) Cancer , vol.59 , pp. 933-935
    • Gilbert, R.D.1    Karabus, C.D.2    Mills, A.E.3
  • 64
    • 0027411688 scopus 로고
    • Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11; 17) translocation associated with acute promyelocytic leukaemia
    • Chen, Z., Brand, N.J., Chen, A., Chen, S.J., Tong, J.H., Wang, Z.Y., Waxman, S. and Zelent, A. (1993) Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11; 17) translocation associated with acute promyelocytic leukaemia. EMBO J., 12, 1161-1167.
    • (1993) EMBO J. , vol.12 , pp. 1161-1167
    • Chen, Z.1    Brand, N.J.2    Chen, A.3    Chen, S.J.4    Tong, J.H.5    Wang, Z.Y.6    Waxman, S.7    Zelent, A.8
  • 65
    • 0029875959 scopus 로고    scopus 로고
    • Pathogenesis and management of acute promyelocytic leukemia
    • Warrell, R.P. Jr (1996) Pathogenesis and management of acute promyelocytic leukemia. Annu. Rev. Med., 47, 555-565.
    • (1996) Annu. Rev. Med. , vol.47 , pp. 555-565
    • Warrell R.P., Jr.1
  • 66
    • 0030061463 scopus 로고    scopus 로고
    • Probing the pathobiology of response to all-trans retinoic acid in acute promyelocytic leukemia: Premature chromosome condensation/fluorescence in situ hybridization analysis
    • Vyas, R.C., Frankel, S.R., Agbor, P., Miller, W.H. Jr, Warrell, R.P. Jr and Hittelman, W.N. (1996) Probing the pathobiology of response to all-trans retinoic acid in acute promyelocytic leukemia: premature chromosome condensation/fluorescence in situ hybridization analysis. Blood, 87, 218-226.
    • (1996) Blood , vol.87 , pp. 218-226
    • Vyas, R.C.1    Frankel, S.R.2    Agbor, P.3    Miller W.H., Jr.4    Warrell R.P., Jr.5    Hittelman, W.N.6
  • 67
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang, M.E., Ye, Y.C., Chen, S.R., Chai, J.R., Lu, J.X., Zhoa, L., Gu, L.J. and Wang, Z.Y. (1988) Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood, 72, 567-572.
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3    Chai, J.R.4    Lu, J.X.5    Zhoa, L.6    Gu, L.J.7    Wang, Z.Y.8
  • 68
    • 0032405602 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: A curable disease
    • Lo Coco, F., Nervi, C., Avvisati, G. and Mandelli, F. (1998) Acute promyelocytic leukemia: a curable disease. Leukemia, 12, 1866-1880.
    • (1998) Leukemia , vol.12 , pp. 1866-1880
    • Lo Coco, F.1    Nervi, C.2    Avvisati, G.3    Mandelli, F.4
  • 69
    • 0026559655 scopus 로고
    • Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia
    • Miller, W.H. Jr, Kakizuka, A., Frankel, S.R., Warrell, R.P. Jr, DeBlasio, A., Levine, K., Evans, R.M. and Dmitrovsky, E. (1992) Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proc. Natl Acad. Sci. USA, 89, 2694-2698.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 2694-2698
    • Miller W.H., Jr.1    Kakizuka, A.2    Frankel, S.R.3    Warrell R.P., Jr.4    DeBlasio, A.L.K.5    Evans, R.M.6    Dmitrovsky, E.7
  • 70
    • 0030771192 scopus 로고    scopus 로고
    • Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia
    • Wells, R.A., Catzavelos, C. and Kamel-Reid, S. (1997) Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia. Nature Genet., 17, 109-113.
    • (1997) Nature Genet. , vol.17 , pp. 109-113
    • Wells, R.A.1    Catzavelos, C.2    Kamel-Reid, S.3
  • 71
    • 0030022316 scopus 로고    scopus 로고
    • The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
    • Redner, R.L., Rush, E.A., Faas, S., Rudert, W.A. and Corey, S.J. (1996) The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood, 87, 882-886.
    • (1996) Blood , vol.87 , pp. 882-886
    • Redner, R.L.1    Rush, E.A.2    Faas, S.3    Rudert, W.A.4    Corey, S.J.5
  • 72
    • 0028899552 scopus 로고
    • Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)
    • Licht, J.D., Chomienne, C., Goy, A., Chen, A., Scott, A.A., Head, D.R., Michaux, J.L., Wu, Y., DeBlasio, A. and Miller, W.H. Jr (1995) Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17). Blood, 85, 1083-1094.
    • (1995) Blood , vol.85 , pp. 1083-1094
    • Licht, J.D.1    Chomienne, C.2    Goy, A.3    Chen, A.4    Scott, A.A.5    Head, D.R.6    Michaux, J.L.7    Wu, Y.8    DeBlasio, A.9    Miller W.H., Jr.10
  • 74
    • 0031033221 scopus 로고    scopus 로고
    • Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences
    • Grisolano, J.L., Wesselschmidt, R.L., Pelicci, P.G. and Ley, T.J. (1997) Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences. Blood, 89, 376-387.
    • (1997) Blood , vol.89 , pp. 376-387
    • Grisolano, J.L.1    Wesselschmidt, R.L.2    Pelicci, P.G.3    Ley, T.J.4
  • 75
    • 0029888693 scopus 로고    scopus 로고
    • A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARα fusion gene transforms haematopoietic progenitors in vitro and induces acute leukaemias
    • Altabef, M., Garcia, M., Lavau, C., Bae, S.C., Dejean, A. and Samarut, J. (1996) A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARα fusion gene transforms haematopoietic progenitors in vitro and induces acute leukaemias. EMBO J., 15, 2707-2716.
    • (1996) EMBO J. , vol.15 , pp. 2707-2716
    • Altabef, M.1    Garcia, M.2    Lavau, C.3    Bae, S.C.4    Dejean, A.5    Samarut, J.6
  • 76
    • 0026742534 scopus 로고
    • Multiplicity generates diversity in the retinoic acid signalling pathways
    • Leid, M., Kastner, P. and Chambon, P. (1992) Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem. Sci., 17, 427-433.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 427-433
    • Leid, M.1    Kastner, P.2    Chambon, P.3
  • 78
    • 0037498052 scopus 로고    scopus 로고
    • Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
    • Muller, S., Matunis, M.J. and Dejean, A. (1998) Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J., 17, 61-70.
    • (1998) EMBO J. , vol.17 , pp. 61-70
    • Muller, S.1    Matunis, M.J.2    Dejean, A.3
  • 79
    • 0031426631 scopus 로고    scopus 로고
    • Evidence for covalent modification of the nuclear dot-associated proteins pml and Sp100 by PICI/SUMO-1
    • Sternsdorf, T., Jensen, K. and Will, H. (1997) Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PICI/SUMO-1. J. Cell Biol., 139, 1621-1634.
    • (1997) J. Cell Biol. , vol.139 , pp. 1621-1634
    • Sternsdorf, T.1    Jensen, K.2    Will, H.3
  • 80
    • 0028972538 scopus 로고    scopus 로고
    • Disruption of pml-associated nuclear bodies during human cytomegalovirus infection
    • Kelly, C., Van Driel, R. and Wilkinson, G.W.G. (1996) Disruption of PML-associated nuclear bodies during human cytomegalovirus infection. J. Gen. Virol., 76, 2887-2893.
    • (1996) J. Gen. Virol. , vol.76 , pp. 2887-2893
    • Kelly, C.1    Van Driel, R.2    Wilkinson, G.W.G.3
  • 81
    • 0030052130 scopus 로고    scopus 로고
    • Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure
    • Doucas, V., Ishov, A.M., Romo, A., Juguilon, H., Weitzman, M.D., Evans, R.M. and Maul, G.G. (1996) Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure. Genes Dev., 10, 196-207.
    • (1996) Genes Dev. , vol.10 , pp. 196-207
    • Doucas, V.1    Ishov, A.M.2    Romo, A.3    Juguilon, H.4    Weitzman, M.D.5    Evans, R.M.6    Maul, G.G.7
  • 82
    • 0028039189 scopus 로고
    • HSV-1 IE protein Vmw110 causes redistribution of PML
    • Everett, R.D. and Maul, G.G. (1994) HSV-1 IE protein Vmw110 causes redistribution of PML. EMBO J., 13, 5062-5069.
    • (1994) EMBO J. , vol.13 , pp. 5062-5069
    • Everett, R.D.1    Maul, G.G.2
  • 84
    • 0032499256 scopus 로고    scopus 로고
    • Recombinant pml adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis
    • Le, X.-F., Vallian, S., Mu, Z.-M., Hung, M.-C. and Chang, K.-S. (1998) Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis. Oncogene, 16, 1839-1849.
    • (1998) Oncogene , vol.16 , pp. 1839-1849
    • Le, X.-F.1    Vallian, S.2    Mu, Z.-M.3    Hung, M.-C.4    Chang, K.-S.5
  • 88
    • 0032482440 scopus 로고    scopus 로고
    • Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein
    • Vallian, S., Gaken, J.A., Gingold, E.B., Kouzarides, T., Chang, K.S. and Farzaneh, F. (1998) Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein. Oncogene, 16, 2843-2853.
    • (1998) Oncogene , vol.16 , pp. 2843-2853
    • Vallian, S.1    Gaken, J.A.2    Gingold, E.B.3    Kouzarides, T.4    Chang, K.S.5    Farzaneh, F.6
  • 90
    • 0028158682 scopus 로고
    • Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells
    • Weis, K., Rambaud, S., Lavau, C., Jansen, J., Carvalho, T., Carmo-Fonseca, M., Lamond, A. and Dejean, A. (1994) Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells. Cell, 76, 345-356.
    • (1994) Cell , vol.76 , pp. 345-356
    • Weis, K.1    Rambaud, S.2    Lavau, C.3    Jansen, J.4    Carvalho, T.5    Carmo-Fonseca, M.6    Lamond, A.7    Dejean, A.8
  • 91
    • 0032546017 scopus 로고    scopus 로고
    • Role of the histone deacetylase complex in acute promyelocytic leukaemia
    • Lin, R.J., Nagy, L., Inoue, S., Shao, W., Miller, W.H. Jr and Evans, R.M. (1998) Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature, 391, 811-814.
    • (1998) Nature , vol.391 , pp. 811-814
    • Lin, R.J.1    Nagy, L.2    Inoue, S.3    Shao, W.4    Miller W.H., Jr.5    Evans, R.M.6
  • 93
    • 0025780876 scopus 로고
    • Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML
    • Kakizuka, A., Miller, W.H. Jr, Umesono, K., Warrell, R.P. Jr, Frankel, S.R., Murty, V.V., Dmitrovsky, E. and Evans, R.M. (1991) Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell, 66, 663-674.
    • (1991) Cell , vol.66 , pp. 663-674
    • Kakizuka, A.1    Miller W.H., Jr.2    Umesono, K.3    Warrell R.P., Jr.4    Frankel, S.R.5    Murty, V.V.6    Dmitrovsky, E.7    Evans, R.M.8
  • 94
    • 0026583943 scopus 로고
    • Structure, localization and transcriptional properties of two classes of retinoic acid receptor α fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins
    • Kastner, P., Perez, A., Lutz, Y., Rochette-Egly, C., Gaub, M.P., Durand, B., Lanotte, M., Berger, R. and Chambon, P. (1992) Structure, localization and transcriptional properties of two classes of retinoic acid receptor α fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins. EMBO J., 11, 629-642.
    • (1992) EMBO J. , vol.11 , pp. 629-642
    • Kastner, P.1    Perez, A.2    Lutz, Y.3    Rochette-Egly, C.4    Gaub, M.P.5    Durand, B.6    Lanotte, M.7    Berger, R.8    Chambon, P.9
  • 97
    • 0028999532 scopus 로고
    • All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia
    • Degos, L., Dombret, H., Chomienne, C., Daniel, M.T., Miclea, J.M., Chastang, C., Castaigne, S. and Fenaux, P. (1995) All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia [see comments]. Blood, 85, 2643-2653.
    • (1995) Blood , vol.85 , pp. 2643-2653
    • Degos, L.1    Dombret, H.2    Chomienne, C.3    Daniel, M.T.4    Miclea, J.M.5    Chastang, C.6    Castaigne, S.7    Fenaux, P.8
  • 98
    • 0026040363 scopus 로고
    • A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients
    • Chen, Z.X., Xue, Y.Q., Zhang, R., Tao, R.F., Xia, X.M., Li, C., Wang, W., Zu, W.Y., Yao, X.Z. and Ling, B.J. (1991) A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients. Blood, 78, 1413-1419.
    • (1991) Blood , vol.78 , pp. 1413-1419
    • Chen, Z.X.1    Xue, Y.Q.2    Zhang, R.3    Tao, R.F.4    Xia, X.M.5    Li, C.6    Wang, W.7    Zu, W.Y.8    Yao, X.Z.9    Ling, B.J.10
  • 102
  • 103
    • 0032170898 scopus 로고    scopus 로고
    • Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner
    • Wang, Z.G., Rivi, R., Delva, L., Konig, A., Scheinberg, D.A., Gambacorti-Passerini, C., Gabrilove, J.L., Warrell, R.P. Jr and Pandolfi, P.P. (1998) Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner. Blood, 92, 1497-1504.
    • (1998) Blood , vol.92 , pp. 1497-1504
    • Wang, Z.G.1    Rivi, R.2    Delva, L.3    Konig, A.4    Scheinberg, D.A.5    Gambacorti-Passerini, C.6    Gabrilove, J.L.7    Warrell R.P., Jr.8    Pandolfi, P.P.9
  • 104
    • 3643104150 scopus 로고    scopus 로고
    • Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
    • Warrell, R.P. Jr. He, L.Z., Richon, V., Calleja, E. and Pandolfi, P.P. (1998) Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J. Natl Cancer Inst., 90, 1621-1625.
    • (1998) J. Natl Cancer Inst. , vol.90 , pp. 1621-1625
    • Warrell R.P., Jr.1    He, L.Z.2    Richon, V.3    Calleja, E.4    Pandolfi, P.P.5
  • 105
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • Petkovich, M., Brand, N.J., Krust, A. and Chambon, P. (1987) A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature, 330, 444-450.
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 106
    • 0023520940 scopus 로고
    • Identification of a receptor for the morphogen retinoic acid
    • Giguere, V., Ong, E.S., Segui, P. and Evans, R.M. (1987) Identification of a receptor for the morphogen retinoic acid. Nature, 330, 624-629.
    • (1987) Nature , vol.330 , pp. 624-629
    • Giguere, V.1    Ong, E.S.2    Segui, P.3    Evans, R.M.4
  • 107
    • 0022598217 scopus 로고
    • Impact of vitamin A supplementation on childhood mortality: A randomized controlled community trial
    • Sommer, A., Tarwotjo, I., Djunaedi, E., West, K.P. Jr and Loeden, A.A. (1986) Impact of vitamin A supplementation on childhood mortality: a randomized controlled community trial. Lancet, i, 1169-1173.
    • (1986) Lancet , vol.1 , pp. 1169-1173
    • Sommer, A.1    Tarwotjo, I.2    Djunaedi, E.3    West K.P., Jr.4    Loeden, A.A.5
  • 109
    • 0028177081 scopus 로고
    • Retinoic acid nuclear receptors and tumor promotion: Decreased expression of retinoic acid nuclear receptors by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate
    • Kumar, R., Shoemaker, A.R. and Verma, A.K. (1994) Retinoic acid nuclear receptors and tumor promotion: decreased expression of retinoic acid nuclear receptors by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis, 15, 701-705.
    • (1994) Carcinogenesis , vol.15 , pp. 701-705
    • Kumar, R.1    Shoemaker, A.R.2    Verma, A.K.3
  • 110
    • 0030997822 scopus 로고    scopus 로고
    • Suppression of retinoic acid receptor β in non-small-cell lung cancer in vivo: Implications for lung cancer development
    • Xu, X.C., Sozzi, G., Lee, J.S., Lee, J.J., Pastorino, U., Pilotti, S., Kurie, J.M., Hong, W.K. and Lotan, R. (1997) Suppression of retinoic acid receptor β in non-small-cell lung cancer in vivo: implications for lung cancer development. J. Natl Cancer Inst., 89, 624-629.
    • (1997) J. Natl Cancer Inst. , vol.89 , pp. 624-629
    • Xu, X.C.1    Sozzi, G.2    Lee, J.S.3    Lee, J.J.4    Pastorino, U.5    Pilotti, S.6    Kurie, J.M.7    Hong, W.K.8    Lotan, R.9
  • 111
    • 0033052303 scopus 로고    scopus 로고
    • Decreased expression of retinoic acid receptors, transforming growth factor beta, involucrin and cornifin in cervical intraepithelial neoplasia
    • Xu, X.C., Mitchell, M.F., Silva, E., Jetten, A. and Lotan, R. (1999) Decreased expression of retinoic acid receptors, transforming growth factor beta, involucrin and cornifin in cervical intraepithelial neoplasia. Clin. Cancer Res., 5, 1503-1508.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1503-1508
    • Xu, X.C.1    Mitchell, M.F.2    Silva, E.3    Jetten, A.4    Lotan, R.5
  • 112
    • 0029044431 scopus 로고
    • Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin
    • Lotan, R., Xu, X.C., Lippman, S.M., Ro, J.Y., Lee, J.S., Lee, J.J. and Hong, W.K. (1995) Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin. N. Engl. J. Med., 332, 1405-1410.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1405-1410
    • Lotan, R.1    Xu, X.C.2    Lippman, S.M.3    Ro, J.Y.4    Lee, J.S.5    Lee, J.J.6    Hong, W.K.7
  • 113
    • 0033024465 scopus 로고    scopus 로고
    • Retinoic acid and 4-hydroxyphenylretinamide induce growth inhibition and tissue transglutaminase through different signal transduction pathways in mouse fibroblasts (NIH 3T3 cells)
    • Giandomenico, V., Andreola, F., de la Concepcion, M.L., Collins, S.J. and De Luca, L.M. (1999) Retinoic acid and 4-hydroxyphenylretinamide induce growth inhibition and tissue transglutaminase through different signal transduction pathways in mouse fibroblasts (NIH 3T3 cells). Carcinogenesis, 20, 1133-1135.
    • (1999) Carcinogenesis , vol.20 , pp. 1133-1135
    • Giandomenico, V.1    Andreola, F.2    De La Concepcion, M.L.3    Collins, S.J.4    De Luca, L.M.5
  • 114
    • 0032477599 scopus 로고    scopus 로고
    • Synthesis of LIAZAL, a retinoic acid metabolism blocking agent (RAMBA) with potential clinical applications in oncology and dermatology
    • Freyne, E., Raeymaekers, A., Venet, M., Sanz, G., Wouters, W., De Coster, R. and Wauwe, J.V. (1998) Synthesis of LIAZAL, a retinoic acid metabolism blocking agent (RAMBA) with potential clinical applications in oncology and dermatology. Bioorg. Med. Chem. Lett., 8, 267-272.
    • (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 267-272
    • Freyne, E.1    Raeymaekers, A.2    Venet, M.3    Sanz, G.4    Wouters, W.5    De Coster, R.6    Wauwe, J.V.7
  • 115
    • 0001832393 scopus 로고    scopus 로고
    • Regional delivery of retinoids: A new approach to early lung cancer intervention
    • Martinet, Y., Hirsch, F.R., Martinet, N. and Vignaud, J.M. (eds) Birkhauser Verlag Ag, Basel, Switzerland
    • Mulshine, J.L., De Luca, L.M. and Dedrick, R.L. (1998) Regional delivery of retinoids: a new approach to early lung cancer intervention. In Martinet, Y., Hirsch, F.R., Martinet, N. and Vignaud, J.M. (eds) Clinical and Biological Basis of Lung Cancer Prevention. Birkhauser Verlag Ag, Basel, Switzerland, Vol. 24, pp. 273-283.
    • (1998) Clinical and Biological Basis of Lung Cancer Prevention , vol.24 , pp. 273-283
    • Mulshine, J.L.1    De Luca, L.M.2    Dedrick, R.L.3
  • 116
    • 0031726065 scopus 로고    scopus 로고
    • Differentiation therapy of leukemia: Achievements, limitations and future prospects
    • Hozumi, M. (1998) Differentiation therapy of leukemia: achievements, limitations and future prospects. Int. J. Hematol., 68, 107-129.
    • (1998) Int. J. Hematol. , vol.68 , pp. 107-129
    • Hozumi, M.1


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