Bovine viral diarrhea virus as a surrogate model of hepatitis C virus for the evaluation of antiviral agents

Antiviral Research

Volumn 60, Issue 1, 2003, Pages 1-15

  Buckwold, Victor E ^a   Beer, Brigitte E ^a   Donis, Ruben O ^b  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

Antiviral; Bovine viral diarrhea virus; Hepatitis C

Indexed keywords

ANTIVIRUS AGENT; LOW DENSITY LIPOPROTEIN RECEPTOR; VIRUS RNA;

BOVINE DIARRHEA VIRUS; DRUG IDENTIFICATION; DRUG SCREENING; DRUG TARGETING; HEPATITIS C; HEPATITIS C VIRUS; INTERNAL RIBOSOME ENTRY SITE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; REPLICON; REVIEW; RNA REPLICATION; STATISTICAL SIGNIFICANCE; VIRION; VIRUS ADSORPTION; VIRUS ASSEMBLY; VIRUS CELL INTERACTION; VIRUS CULTURE; VIRUS INFECTIVITY; VIRUS MORPHOLOGY; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

BOVINAE; BOVINE VIRAL DIARRHEA VIRUS 1; HEPATITIS C VIRUS;

EID: 0141456064     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(03)00174-8     Document Type: Review

References (141)

1. Adler H., Frech B., Meier P., Jungi T.W., Peterhans E. Noncytopathic strains of bovine viral diarrhea virus prime bovine bone marrow-derived macrophages for enhanced generation of nitric oxide. Biochem. Biophys. Res. Commun. 202:1994;1562-1568.
2. Agnello V., Ábel G., Elfahal M., Knight G.B., Zhang Q.-X. Hepatitis C virus and other Flaviviridae viruses enter cells via low density lipoprotein receptor. Proc. Natl. Acad. Sci. USA. 96:1999;12766-12771.
3. Ali N., Siddiqui A. Interaction of polypyrimidine tract-binding protein with the 5′ noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation. J. Virol. 69:1995;6367-6375.
4. Ali N., Siddiqui A. The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation. Proc. Natl. Acad. Sci. USA. 94:1997;2249-2254.
5. Andre P., Komurian-Pradel F., Deforges S., Perret M., Berland J.L., Sodoyer M., Pol S., Brechot C., Paranhos-Baccala G., Lotteau V. Characterization of low- and very-low-density hepatitis C virus RNA-containing particles. J. Virol. 76:2002;6919-6928.
6. Baginski S.G., Pevear C.D., Seipel M., Sun S.C.C., Benetatos C.A., Chunduru S.K., Rice C.M., Collett M.S. Mechanism of action of a pestivirus antiviral compound. Proc. Natl. Acad. Sci. USA. 97:2000;7981-7986.
7. Baigent S.J., Zhang G., Fray M.D., Flick-Smith H., Goodbourn S., McCauley J.W. Inhibition of beta interferon transcription by noncytopathogenic bovine viral diarrhea virus is through an interferon regulatory factor 3-dependent mechanism. J. Virol. 76:2002;8979-8988.
8. Bartenschlager R., Lohmann V. Novel cell culture systems for the hepatitis C virus. Antiviral Res. 52:2001;1-17.
9. Bazan J.F., Fletterick R.J. Structural and catalytic models of trypsin-like viral proteases. Sem. Virol. 1:1990;311-322.
10. Beales L.P., Holzenburg A., Rowlands D.J. Viral internal ribosome entry site structures segregate into two distinct morphologies. J. Virol. 77:2003;6574-6579.
11. Beames B., Chavez D., Lanford R.E. GB virus B as a model for hepatitis C virus. ILAR J. 42:2001;152-160.
12. Becher P., Orlich M., Thiel H.-.J. Mutations in the 5′ nontranslated region of bovine viral diarrhea virus result in altered growth characteristics. J. Virol. 74:2000;7884-7894.
13. Bielefeldt O.H. Double-immunolabeling systems for phenotyping of immune cells harboring bovine viral diarrhea virus. J. Histochem. Cytochem. 35:1987;627-633.
14. Bielefeldt O.H. In situ characterization of mononuclear leukocytes in skin and digestive tract of persistently bovine viral diarrhea virus-infected clinically healthy calves and calves with mucosal disease. Vet. Pathol. 25:1988;304-309.
15. Bielefeldt O.H., Ronsholt L., Bloch B. Demonstration of bovine viral diarrhoea virus in peripheral blood mononuclear cells of persistently infected, clinically normal cattle. J. Gen. Virol. 68:1987;1971-1982.
16. Block T.M., Lu X., Mehta A.S., Blumberg B.S., Tennant B., Ebling M., Korba B., Lansky D.M., Jacob G.S., Dwek R.A. Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking. Nat. Med. 4:1998;610-614.
17. Bodenheimer H.C. Jr., Lindsay K.L., Davis G.L., Lewis J.H., Thung S.N., Seef L.B. Tolerance and efficacy of oral ribavirin treatment of chronic hepatitis C: a multicenter trial. Hepatology. 26:1997;473-477.
18. Bolin A.R., McClurkin A.W., Coria M.F. Frequency of persistent bovine viral diarrhea virus infection in selected cattle herds. AJVR. 46:1985;2385-2387.
19. Borowski P., Schalinski S., Schmitz H. Nucleotide triphosphatase/ helicase of hepatitis C virus as a target for antiviral therapy. Antiviral Res. 55:2002;397-412.
20. Brownlie J., Clarke M.C., Howard C.J. Experimental infection of cattle in early pregnancy with a cytopathic strain of bovine virus diarrhoea virus. Res. Vet. Sci. 46:1989;307-311.
21. Buckwold V.E., Wei J., Wenzel-Mathers M., Russell J. Synergistic in vitro interactions between alpha interferon and ribavirin against bovine viral diarrhea virus and yellow fever virus as surrogate models of hepatitis C virus replication. Antimicrob. Agents Chemother. 47:2003;2293-2298.
22. Castet V., Fournier C., Soulier A., Brillet R., Coste J., Larrey D., Dhumneaux D., Maurel P., Pawlotsky J.-M. Alpha interferon inhibits hepatitis C virus replication in primary human hepatocytes infected in vitro. J. Virol. 76:2002;8189-8199.
23. Charleston B., Fray M.D., Baigent S., Carr B.V., Morrison W.I. Establishment of persistent infection with non-cytopathic bovine viral diarrhoea virus in cattle is associated with a failure to induce type I interferon. J. Gen. Virol. 82:2001;1893-1897.
24. Cheney I.W., Lai V.C.H., Zhong W., Brodhag T., Dempsey S., Lim C., Hong Z., Lau J.Y.N., Tam R.C. Comparative analysis of anti-hepatitis C virus activity and gene expression mediated by alpha, beta, and gamma interferons. J. Virol. 76:2002;11148-11154.
25. Chon S.K., Perez D.R., Donis R.O. Genetic analysis of the internal ribosome entry site of bovine viral diarrhea virus. Virology. 251:1998;370-382.
26. Choo Q.-L., Richman K., Han J.H., Berger K., Lee C., Dong C., Gallegos C., Coit D., Medina-Selby A., Barr P.J., Weiner A., Bradley D.W., Kuo G., Houghton M. Genetic organization and diversity of the hepatitis C virus. Proc. Natl. Acad. Sci. USA. 88:1991;2451-2455.
27. Colett M.S., Larson R., Gold C., Strick D., Anderson D.K., Purchio A.F. Molecular cloning and nucleotide sequence of the pestivirus bovine viral diarrhea virus. Virology. 165:1988;191-199.
28. Contreras A.M., Hiasa Y., He W., Terella A., Schmidt E.V., Chung R.T. Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system. J. Virol. 76:2002;8505-8517.
29. Crotty S., Maag D., Arnold J.J., Zhong W., Lau J.Y., Hong Z., Andino R., Cameron C.E. The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nat. Med. 6:2000;1375-1379.
30. Crotty S., Cameron C.E., Andino R. RNA virus error catastrophe: direct molecular test by using ribavirin. Proc. Natl. Acad. Sci. USA. 98:2001;6895-6900.
31. Das S., Ott M., Yamane A., Tsai W., Gromeier M., Lahser F., Gupta S., Dasgupta A. A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element. J. Virol. 72:1998;5638-5647.
32. Di Bisceglie A.M., Conjeevaram H.S., Fried M.W., Sallie R., Park Y., Yurdaydin C., Swain M., Kleiner D.E., Mahaney K., Hoofnagle J.H. Ribavirin as therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. Ann. Int. Med. 123:1995;897-903.
33. Donis R.O. Molecular biology of bovine viral diarrhea virus and its interactions with the host. Vet. Clin. North Am. Food Anim. Pract. 11:1995;393-423.
34. Donis R.O., Dubovi E.J. Characterization of bovine viral diarrhoea-mucosal disease virus-specific proteins in bovine cells. J. Gen. Virol. 68:1987a;1597-1605.
35. Donis R.O., Dubovi E.J. Differences in virus-induced polypeptides in cells infected by cytopathic and noncytopathic biotypes of bovine virus diarrhea-mucosal disease virus. Virology. 158:1987b;168-173.
36. Donis R.O., Dubovi E.J. Glycoproteins of bovine viral diarrhoea-mucosal disease virus in infected bovine cells. J. Gen. Virol. 68:1987c;1607-1616.
37. Donis R., Corapi W., Dubovi E. Bovine viral diarrhea and their antigenic analyses. Arch. Virol. Suppl. 3:1991;29-40.
38. Durantel D., Branza-Nichita N., Carrouee-Durantel S., Butters T.D., Dwek R.A., Zitzmann N. Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus. J. Virol. 75:2001;8987-8998.
39. Dushieko G., Main J., Thomas H., Reichard O., Lee C., Dhillon A., Rassam S., Fryden A., Ressink H., Bassendine M., Norkrans G., Cuypers T., Lelie N., Tefler P., Watson J., Sillikens C., Weiland O. Ribavirin treatment for patients with chronic hepatitis C: Results of a placebo-controlled study. J. Hepatol. 25:1996;591-598.
40. Enomoto N., Sakuma I., Asahina Y., Kurosaki M., Murakami T., Yamamoto C., Izumi N., Marumo F., Sato C. Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J. Clin. Invest. 96:1995;224-230.
41. Favre D., Berthillon P., Trepo C. Removal of cell-bound lipoproteins: a crucial step for the efficient infection of liver cells with hepatitis C virus in vitro. C. R. Acad. Sci. III. 324:2001;1141-1148.
42. Flores E., Donis R. Isolation of a mutant MDBK cell line resistant to bovine viral diarrhea virus infection due to a block in viral entry. Virology. 208:1995;565-575.
43. Frese M., Pietschmann T., Moradpour D., Haller O., Bartenschlager R. Interferon-α inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway. J. Gen. Virol. 82:2001;723-733.
44. Friebe P., Bartenschlager R. Genetic analysis of sequences in the 3′ nontranslated region of hepatitis C virus that are important for RNA replication. J. Virol. 76:2002;5326-5338.
45. Friebe P., Lohmann V., Krieger N., Bartenschlager R. Sequences in the 5′ nontranslated region of hepatitis C virus required for RNA replication. J. Virol. 75:2001;12047-12057.
46. Frolov I., McBride M.S., Rice C.M. cis-acting RNA elements required for replication of bovine viral diarrhea virus-hepatitis C virus 5′ nontranslated region chimeras. RNA. 4:1998;1418-1435.
47. Fukushi S., Kurihara C., Ishiyama N., Hoshino F.B., Oya A., Katayama K. The sequence element of the internal ribosome entry site and a 25-kDa cellular protein contribute to efficient internal initiation of translation of hepatitis C virus RNA. J. Virol. 71:1997;1662-1666.
48. Gallego J., Varani G. The hepatitis C virus internal ribosome-entry site: a new target for antiviral research. Biochem. Soc. Trans. 30:2002;140-145.
49. Gardner J.P., Durso R.J., Arrigale R.R., Donovan G.P., Maddon P.J., Dragic T., Olson W.C. L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus. Proc. Natl. Acad. Sci. USA. 100:2003;4498-4503.
50. Gowans E.J. Distribution of markers of hepatitis C virus infection throughout the body. Semin. Liver Dis. 20:2000;85-102.
51. Graci J.D., Cameron C.E. Quasispecies, error catastrophe, and the antiviral activity of ribavirin. Virology. 298:2002;175-180.
52. Grassmann C.W., Isken O., Tautz N., Behrens S.E. Genetic analysis of the pestivirus nonstructural coding region: defects in the NS5A unit can be complemented in trans. J. Virol. 75:2001;7791-7802.
53. Griffin S.D., Beales L.P., Clarke D.S., Worsfold O., Evans S.D., Jaeger J., Harris M.P., Rowlands D.J. The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, amantadine. FEBS Lett. 535:2003;34-38.
54. Grummer B., Beer M., Liebler-Tenorio E., Greiser-Wilke I. Localization of viral proteins in cells infected with bovine viral diarrhoea virus. J. Gen. Virol. 82:2001;2597-2605.
55. Gu B., Liu C., Lin-Goerke J., Maley D.R., Gutshall L.L., Feltenberger C.A., Del Vecchio A.M. The RNA helicase and nucleotide triphosphatase activities of the bovine viral diarrhea virus NS3 protein are essential for viral replication. J. Virol. 74:2000;1794-1800.
56. Guo J.-T., Bichko V.V., Seeger C. Effect of alpha interferon on the hepatitis C virus replicon. J. Virol. 75:2001;8516-8523.
57. Gutfreund K.S., Bain V.C. Chronic viral hepatitis C: Management update. CMAJ. 162:2000;827-833.
58. Hahm B., Kim Y.K., Kim J.H., Kim T.Y., Jang S.K. Heterogeneous nuclear ribonucleoprotein L interact with the 3′ border of the internal ribosome entry site of hepatitis C virus. J. Virol. 72:1998;8782-8788.
59. Han J.H., Shyamala V., Richman K.H., Brauer M.J., Irvine B., Urdea M.S., Tekamp-Olson P., Kuo G., Choo Q., Houghton M. Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5′ untranslated region and poly(A) tails at the 3′ end. Proc. Natl. Acad. Sci. USA. 88:1991;1711-1715.
60. Hanecaki R., Brown-Driver V., Fox M.C., Azad R.F., Furosako S., Nozaki C., Ford C., Sasmor H., Anderson K.P. Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes. J. Virol. 70:1996;5203-5212.
61. Harding M.J., Cao X., Shams H., Johnson A.F., Vassilev V.B., Gil L.H., Wheeler D.W., Haines D., Sibert G.J., Nelson L.D., Campos M., Donis R.O. Role of bovine viral diarrhea virus biotype in the establishment of fetal infections. Am. J. Vet. Res. 63:2002;1455-1463.
62. Hellen C.U., Pestova T.V. Translation of hepatitis C virus RNA. J. Viral Hepat. 6:1999;79-87.
63. Hoofnagle J.H. Course and outcome of hepatitis C. Hepatology. 36(Suppl 1):2002;S21-S29.
64. Iqbal M., Flick-Smith H., McCauley J.W. Interactions of bovine viral diarrhoea virus glycoprotein E(rns) with cell surface glycosaminoglycans. J. Gen. Virol. 81:2000;451-459.
65. Jubin R. Hepatitis C IRES: translating translation into a therapeutic target. Curr. Opin. Mol. Ther. 3:2001;278-287.
66. Kadaré G., Haenni A.-L. Virus-encoded RNA helicases. J. Virol. 71:1997;2583-2590.
67. Kao C.C., Del Vecchio A.M., Zhong W. De novo initiation of RNA synthesis by a recombinant flaviviridae RNA-dependent RNA polymerase. Virology. 253:1999;1-7.
68. Kato N. Genome of human hepatitis C virus (HCV): gene organization, sequence diversity, and variation. Microb. Comp. Genet. 5:2000;129-151.
69. Kayali Z., Buckwold V.E., Zimmerman B., Schmidt W.N. Hepatitis C, cryoglobulinemia, and cirrhosis: a meta-analysis. Hepatology. 36:2002;978-985.
70. Khabar K.S., Polyak S.J. Hepatitis C virus-host interactions: the NS5A protein and the interferon/chemokine systems. J. Interferon Cytokine Res. 22:2002;1005-1012.
71. Kieft J.S., Zhou K., Jubin R., Doudna J.A. Mechanism of ribosome recruitment by hepatitis C IRES RNA. RNA. 7:2001;194-206.
72. Kim Y.K., Kim C.S., Lee S.H., Jang S.K. Domains I and II in the 5′ nontranslated region of the HCV genome are required for RNA replication. Biochem. Biophys. Res. Commun. 290:2002a;105-112.
73. Kim W.R., Brown R.S. Jr., Terrault N.A., El-Serag H. Burden of liver disease in the United States: summary of a workshop. Hepatology. 36:2002b;227-242.
74. Kolykhalov A.A., Mihalik K., Feinstone S.M., Rice C.M. Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo. J. Virol. 74:2000;2046-2051.
75. Krüger M., Beger C., Welch P.J., Barber J.R., Manns M.P., Wong-Staal F. Involvement fo proteosome α-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation. Mol. Cell. Biol. 21:2001;8357-8364.
76. Lai V.C., Kao C.C., Ferrari E., Park J., Uss A.S., Wright-Minogue J., Hong Z., Lau J.Y. Mutational analysis of bovine viral diarrhea virus RNA-dependent RNA polymerase. J. Virol. 73:1999;10129-10136.
77. Lai V.C., Zhong W., Skelton A., Ingravallo P., Vassilev V., Donis R.O., Hong Z., Lau J.Y. Generation and characterization of a hepatitis C virus NS3 protease-dependent bovine viral diarrhea virus. J. Virol. 74:2000;6339-6347.
78. Lanford R.E., Chavez D., Guerra B., Lau J.Y., Hong Z., Brasky K.M., Beames B. Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes. J. Virol. 75:2001;8074-8081.
79. Lanford R.E., Guerra B., Lee H., Averett D.R., Pfeiffer B., Chavez D., Notvall L., Bigger C. Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(I)-poly(C), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons. J. Virol. 77:2003;1092-1104.
80. Lau J.Y.N., Tam R.C., Lang T.J., Hong Z. Mechanism of action of ribavirin in the combination treatment of chronic HCV infection. Hepatology. 35:2002;1002-1009.
81. Liang T.J., Rehermann B., Seeff L.B., Hoofnagle J.H. Pathogenesis, natural history, treatment and prevention of hepatitis C. Ann. Int. Med. 132:2000;296-305.
82. Lindenbach, B.D., Rice, C.M., 2001. Flaviviridae: the viruses and their replication, In: Knipe, D.M., Howley, P.M., Griffin, D.E., Lamb, R.A., Martin, M.A., Roizman, B. (Eds.), Fields Virology, 4th edn., Vol. 1. Lippincott Williams & Wilkins, Philadelphia, PA, pp. 991-1041.
83. Lohmann V., Körner F., Koch J.-O., Herian U., Thielmann L., Bartenschlager R. Replication of subgenomic hepatitis C virus RNA in a hepatoma cell line. Science. 285:1999a;110-113.
84. Lohmann V., Overton H., Bartenschlager R. Selective stimulation of hepatitis C virus and pestivirus NS5B RNA polymerase activity by GTP. J. Biol. Chem. 274:1999b;10807-10815.
85. Lopez de Quinto S., Lafuente E., Martinez-Salas E. IRES interaction with translation initiation factors: functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GI. RNA. 7:2001;1213-1226.
86. Lu X., Mehta A., Dadmarz M., Dwek R., Blumberg B.S., Block T.M. Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited. Proc. Natl. Acad. Sci. USA. 94:1997;2380-2385.
87. Maag D., Castro C., Hong Z., Cameron C.E. Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin. J. Biol. Chem. 276:2001;46094-46098.
88. Markland W., McQuaid T.J., Jain J., Kwong A.D. Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-409: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon. Antimicrob. Agents Chemother. 44:2000;859-866.
89. Masciopinto F., Freer G., Burgio V.L., Levy S., Galli-Stampino L., Bendinelli M., Houghton M., Abrignani S., Uematsu Y. Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection. Virology. 304:2002;187-196.
90. McClurkin A.W., Littledike E.T., Cutlip R.C., Frank G.H., Coria M.F., Bolin S. Production of cattle immunotolerant to bovine viral diarrhea virus. Can. J. Comp. Med. 48:1984;156-161.
91. Meyers G., Thiel H.J. Molecular characterization of pestiviruses. Adv. Virus Res. 47:1996;53-118.
92. Meyers G., Tautz N., Becher P., Thiel H.J., Kummerer B.M. Recovery of cytopathogenic and noncytopathogenic bovine viral diarrhea viruses from cDNA constructs. J. Virol. 70:1996;8606-8613.
93. Miller R.H., Purcell R.H. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proc. Natl. Acad. Sci. USA. 87:1990;2057-2061.
94. Minocha H.C., Xue W., Reddy J.R. A 50 kDa membrane protein from bovine kidney cells is a putative receptor for bovine viral diarrhea virus (BVDV). Adv. Exp. Med. Biol. 412:1997;145-148.
95. Monazahian M., Böhme I., Bonk S., Koch A., Scholz C., Grethe S., Thomssen R. Low density lipoprotein receptor as a candidate receptor for hepatitis C virus. J. Med. Virol. 57:1999;223-229.
96. Muerhoff A.S., Leary T.P., Simons J.N., Pilot-Matias T.J., Dawson G.J., Erker J.C., Chalmers M.L., Schlauder G.G., Desai S.M., Mushahwar I.K. Genomic organization of GB viruses A and B: two new members of the Flaviviridae associated with GB agent hepatitis. J. Virol. 69:1995;5621-5630.
97. Nehls S., Snapp E.L., Cole N.B., Zaal K.J., Kenworthy A.K., Roberts T.H., Ellenberg J., Presley J.F., Siggia E., Lippincott-Schwartz J. Dynamics and retention of misfolded proteins in native ER membranes. Nat. Cell Biol. 2:2000;288-295.
98. Neyts J., Meerbach A., McKenna P., De Clercq E. Use of yellow fever virus vaccine strain 17D for the study of strategies for the treatment of yellow fever virus infections. Antiviral Res. 30:1996;125-132.
99. Odeon A.C., Kelling C.L., Marshall D.J., Estela E.S., Dubovi E.J., Donis R.O. Experimental infection of calves with bovine viral diarrhea virus genotype II (NY-93). J. Vet. Diagn. Invest. 11:1999;221-228.
100. O'Reilly E.K., Kao C.C. Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structures. Virology. 252:1998;287-303.
101. Ouzounov S., Mehta A., Dwek R.A., Block T.M., Jordan R. The combination of interferon α-2b and n-butyl deoxynojirimycin has a greater than additive antiviral effect upon production of infectious bovine viral diarrhea virus (BVDV) in vitro: implications for hepatitis C virus therapy. Antiviral Res. 55:2002;425-435.
102. Pavlovic D., Neville D.C., Argaud O., Blumberg B., Dwek R.A., Fischer W.B., Zitzmann N. The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives. Proc. Natl. Acad. Sci. USA. 100:2003;6104-6108.
103. Perni R.B., Kwong A.D. Inhibitors of hepatitis C virus NS3.4A protease: an overdue line of therapy. Prog. Med. Chem. 39:2002;215-255.
104. Pestova T.V., Shatsky I.N., Fletcher S.P., Jackson R.J., Hellen C.U. A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs. Genes Dev. 12:1998;67-83.
105. Pestova T.V., Kolupaeva V.G., Lomakin I.B., Philipenko E.V., Shatsky I.N., Agol V.I., Hellen C.U.T. Molecular mechanisms of translation initation in eukaryotes. Proc. Natl. Acad. Sci. USA. 98:2001;7029-7036.
106. Petracca R., Falugi F., Galli G., Norais N., Rosa D., Campognoli S., Burgio V., Di Strasio E., Giardina B., Houghton M., Abrignani S., Grandi G. Structure-function analysis of hepatitis C virus envelope-CD81 binding. J. Virol. 74:2000;4824-4830.
107. Pileri P., Uematsu Y., Campagnoli S., Galli G., Falugi F., Petracca R., Weiner A.J., Houghton M., Rosa D., Grandi G., Abrignani S. Binding of hepatitis C virus to CD81. Science. 282:1998;938-941.
108. Robertson B., Myers G., Howard C., Brettin T., Bukh J., Gaschen B., Gojobori T., Maertens G., Mizokami M., Nainan O., Netesov S., Nishioka K., Shin-i T., Simmonds P., Smith D., Stuyver L., Weiner A. Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization. Arch. Virol. 143:1998;2493-2503.
109. Rosenberg S. Recent advances in the molecular biology of hepatitis C virus. J. Mol. Biol. 313:2001;451-464.
110. Sanderbrand S.A., Tautz N., Thiel H.J., Ochs K., Beck E., Niepmann M. Translation from the internal ribosome entry site of bovine viral diarrhea virus is independent of the interaction with polypyrimidine tract-binding protein. Vet. Microbiol. 77:2000;215-227.
111. Sasaki M., Yamauchi K., Nakanishi T., Kamogawa Y., Hayashi N. In vitro binding of hepatitis C virus to CD81-positive and -negative human cell lines. J. Gastroenterol. Hepatol. 18:2003;74-79.
112. Scarselli E., Ansuini H., Cerino R., Filocamo G., Traboni C., Nicosia A., Cortese R., Vitelli A. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21:2002;5017-5025.
113. Schelp C., Greiser-Wilke I., Wolf G., Beer M., Moennig V., Liess B. Identification of cell membrane proteins linked to susceptibility to bovine viral diarrhoea virus infection. Arch. Virol. 140:1995;1997-2009.
114. Schelp C., Greiser-Wilke I., Moennig V. An actin-binding protein is involved in pestivirus entry into bovine cells. Virus Res. 68:2000;1-5.
115. Schneider R., Unger G., Stark R., Schneider-Scherzer E., Thiel H.J. Identification of a structural glycoprotein of an RNA virus as a ribonuclease. Science. 261:1993;1169-1171.
116. Seki M., Honda Y. Phosphorothioate antisense oligodeoxynucleotides capable of inhibiting hepatitis C virus gene expression: in vitro translation assay. J. Biochem. 118:1995;1199-1204.
117. Seo M.Y., Abrignani S., Houghton M., Han J.H. Small interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh7. J. Virol. 77:2003;810-812.
118. Shimoike T., Mimori S., Tani H., Matsuura Y., Miyamura T. Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation. J. Virol. 73:1999;9718-9725.
119. Silva-Krott I.U., Kennedy M.A., Potgieter L.N. Cloning, sequencing, and in vitro expression of glycoprotein gp48 of a noncytopathogenic strain of bovine viral diarrhea virus. Vet. Microbiol. 39:1994;1-14.
120. Steffens S., Thiel H.J., Behrens S.E. The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro. J. Gen. Virol. 80:1999;2583-2590.
121. Stuyver L.J., Whitaker T., McBrayer T.R., Hernandez-Santiago B.I., Lostia S., Tharnish P.M., Ramesh M., Chu C.K., Jordan R., Shi J., Rachakonda S., Watanabe K.A., Otto M.J., Schinazi R.F. Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture. Antimicrob. Agents Chemother. 47:2003;244-254.
122. Sun J.-H., Lemm J.A., O'Boyle D.R. II, Racela J., Colonmo R., Gao M. Specific inhibition of bovine viral diarrhea virus replicase. J. Virol. 77:2003;6753-6760.
123. Swasdipan S., McGowan M., Phillips N., Bielefeldt-Ohmann H. Pathogenesis of transplacental virus infection: pestivirus replication in the placenta and fetus following respiratory infection. Microb. Pathog. 32:2002;49-60.
124. Tanabe, Y., Sakamoto, N., Maekawa, S., Kurosaki, M., Yamashiro, T., Enomoto, N., 2002. Synergistic effects of ribavirin and alpha-interpheron on intracellular hepatitis C virus relplication in Huh7 cells. In: Proceedings of the Nineth International Meeting on HCV and Related Viruses (abstract 95).
125. Tautz N., Elbers K., Stoll D., Meyers G., Thiel H.J. Serine protease of pestiviruses: determination of cleavage sites. J. Virol. 71:1997;5415-5422.
126. Tratschin J.D., Moser C., Ruggli N., Hofmann M.A. Classical swine fever virus leader proteinase Npro is not required for viral replication in cell culture. J. Virol. 72:1998;7681-7684.
127. Triyatni M., Saunier B., Maruvada P., Davis A.R., Ulianich L., Heller T., Patel A., Kohn L.D., Liang T.J. Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entry. J. Virol. 76:2002;9335-9344.
128. Vassilev V., Collett M., Donis R. Authentic and chimeric full-length genomic cDNA clones of bovine viral diarrhea virus that yield infectious transcripts. J. Virol. 71:1997;471-478.
129. Walker J.E., Saraste M., Runswick M.J., Gay N.J. Distantly related sequences in the α- and β-subunits of ATP synthetase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:1982;945-951.
130. Westaway E.G., Brinton M.A., Gaidamovich S.Y., Horzinek M.C., Igarashi A., Kääriäinen L., Lvov D.K., Porterfield J.S., Russell P.K., Trent D.W. Flaviviridae. Intervirology. 24:1985;183-192.
131. Wills R.C., Carson D.A., Seegmiller J.E. Adenosine kinase initiates the major source of ribavirin activation in a cultured human cell line. Proc. Natl. Acad. Sci. USA. 75:1978;3042-3044.
132. World Health Organization, 2002. Global surveillance and control of hepatitis C. J. Viral Hepat. 6, 35-47.
133. Wiskerchen M., Belzer S.K., Collett M.S. Pestivirus gene expression: the first protein product of the bovine viral diarrhea virus large open reading frame, p20, possesses proteolytic activity. J. Virol. 65:1991;4508-4514.
134. Wünschmann S., Medh J.D., Klinzmann D., Schmidt W.N., Stapleton J.T. Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor. J. Virol. 74:2000;10055-10062.
135. Xu J., Mendez E., Caron P.R., Lin C., Murcko M.A., Collet M.S., Rice C.M. Bovine viral diarrhea virus NS3 proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication. J. Virol. 71:1997;5312-5322.
136. Yamaga, A.K. Choi, J., Ou, J.-.H., 2002. Effects of ribavirin and interferon on the replication of hepatitis C virus subgenomic RNA replicons. In: Proceedings of the Nineth International Meeting on HCV and Related Viruses (abstract 106).
137. Yu H., Isken O., Grassmann C.W., Behrens S.-E. A stem-loop motif formed by the immediate 5′ terminus of the bovine viral diarrhea virus genome modulates translation as well as replication of the viral RNA. J. Virol. 74:2000;5825-5835.
138. Zhong W., Gutshall L.L., Del Vecchio A.M. Identification and characterization of an RNA-dependent RNA polymerase activity within the nonstructural protein 5B region of bovine viral diarrhea virus. J. Virol. 72:1998;9365-9369.
139. Zhou X., Tang Z.Y., Klumpp B., Wolf-Vorbeck G., Barth H., Levy S., von Weizsacker F., Blum H.E., Baumert T.F. Primary hepatocytes of Tupia belangeri as a potential model for hepatitis C virus infection. J. Clin. Invest. 109:2002;221-232.
140. Zhou S., Liu R., Baroudy B.M., Malcom B.A., Reyes G.R. The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA. Virology. 310:2003;333-342.
141. Zitzmann N., Mehta A.S., Carrouee S., Butters T.D., Platt F.M., McCauley J., Blumberg B.S., Dwek R.A., Block T.M. Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C: implications for the development of broad spectrum anti-hepatitis virus agents. Proc. Natl. Acad. Sci. USA. 96:1999;11878-11882.