IRES interaction with translation initiation factors: Functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GII

RNA

Volumn 7, Issue 9, 2001, Pages 1213-1226

  Lopez De Quinto S ^a   Lafuente, E ^a   Martinez Salas E ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

Foot and mouth disease virus (FMDV); IRES; RNA protein interaction; Translation initiation factors (eIF)

Indexed keywords

CIS ACTING ELEMENT; INITIATION FACTOR; INITIATION FACTOR 3; INITIATION FACTOR 4B; INITIATION FACTOR 4GII; PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN BHK; CONTROLLED STUDY; FOOT AND MOUTH DISEASE VIRUS; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RIBOSOME; TRANSLATION INITIATION;

ANIMALS; APHTHOVIRUS; BASE SEQUENCE; CELL LINE; CRICETINAE; ENDOPEPTIDASES; EUKARYOTIC INITIATION FACTOR-4G; EUKARYOTIC INITIATION FACTORS; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PEPTIDE INITIATION FACTORS; PROKARYOTIC INITIATION FACTOR-3; RNA, VIRAL; RNA-BINDING PROTEINS;

ANIMALIA; FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE;

EID: 0034852292     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838201010433     Document Type: Article

References (62)

1. A Saccharomyces cerevisiae homologue of mammalian translation initiation factor 4B contributes to RNA helicase activity
2. The Saccharomyces cerevisiae translation initiation factor Tif3 and its mammalian homologue eIF-4B have RNA annealing activity
3. Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus
4. Conservation and diversity of eukaryotic translation initiation factor eIF3
5. Translation initiation on picornavirus RNA
6. Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3
7. Comparison of picornaviral IRES-driven internal initiation of translation in cultured cells of different origins
8. Functional analysis of the interaction between HCV 5′ UTR and putative subunits of eukaryotic translation initiation factor eIF3
9. Cellular internal ribosome entry site elements and the use of cDNA microarrays in their investigation
10. A new yeast translation initiation factor suppresses a mutation in the eIF-4A RNA helicase
11. Identification and quantitation of levels of protein synthesis initiation factors in crude HeLa cell lysates by two-dimensional polyacrylamide gel electrophoresis
12. Modifications of the 5′ untranslated region of foot-and-mouth disease virus after prolonged persistence in cell cultures
13. Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase
14. Two functional complexes formed by KH domain containing proteins with the 5′ noncoding region of poliovirus RNA
15. eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
16. Poliovirus 2A protease induces apoptotic cell death
17. A novel functional human eukaryotic translation initiation factor 4G
18. Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
19. A new pathway of translation regulation mediated by eukaryotic initiation factor 3
20. Pathway and mechanism of initiation of protein synthesis
21. A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
22. Mechanism of ribosome recruitment by hepatitis C IRES RNA
23. Foot-and-mouth disease virus leader proteinase: Purification of the Lb form and determination of its cleavage site on eIF-4 gamma
24. Ribosomal binding to the internal ribosomal entry site of classical swine fever virus
25. Eukaryotic translation initiation factor 4G recognizes a specific structural element within the internal ribosome entry site of encephalomyocarditis virus RNA
26. Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translation initiation
27. Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation
28. Conserved structural motifs located in distal loops of the aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation
29. Parameters influencing translational efficiency in aphthovirus IRES-based bicistronic expression vectors
30. Involvement of the aphthovirus RNA region located between the two functional AUGs in start codon selection
31. Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal initiation of translation in vivo
32. Interaction of a cellular 57-kilodalton protein with the internal translation initiation site of foot-and-mouth disease virus
33. A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery
34. Functional interactions in internal translation initiation directed by viral and cellular IRES elements
35. Identification of an essential domain for internal initiation of translation in the aphthovirus IRES, and implications for viral evolution
36. A single nucleotide substitution in the internal ribosome entry site of foot-and-mouth disease virus leads to enhanced cap-independent translation in vivo
37. Eukaryotic protein synthesis initiation factor eIF-3: Determination of concentration and association with ribosomes in rabbit reticulocyte and HeLa cell lysates
38. The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence
39. In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: The role of the RNA recognition motif
40. The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170
41. A region rich in aspartic acid, arginine, tyrosine, and glicine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3
42. Interaction of eukaryotic initiation factor eIF-4B with a picornavirus internal translation initiation site
43. Immunochemical characterization of mammalian protein synthesis initiation factors
44. Immunoblot analysis of the structure of protein synthesis initiation factor eIF3 from HeLa cells
45. Cloning and expression of eukaryotic initiation factor 4B: Sequence determination identifies a common RNA recognition motif
46. Two structural domains of initiation factor eIF-4B are involved in binding to RNA
47. Specific interaction of one subunit of eukaryotic initiation factor eIF-3 with 18S ribosomal RNA within the binary complex, eIF-3-small ribosomal subunit, as shown by cross-linking experiments
48. Influence of correct secondary and tertiary RNA folding on the binding of cellular factors to the HCV IRES
49. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
50. Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons
51. Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry
52. A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal initiation of hepatitis C and classical swine fever virus RNAs
53. A cell cycle-dependent protein serves as a template-specific translation initiation factor
54. From factors to mechanism: Translation and translational control in eukaryotes
55. Long-range RNA interactions between structural domains of the aphthovirus internal ribosome entry site (IRES)
56. A new cationic liposome reagent mediating nearly quantitative transfection of animal cells
57. Bidirectional RNA helicase activity of eukaryotic translation initiation factor 4A and 4F
58. Internal initiation of translation efficiency in different hepatitis C genotypes isolated from interferon treated patients
59. Specific interaction of eukaryotic translation initiation factor 3 with the 5′ nontranslated regions of hepatitis C virus and classical swine fever virus RNAs
60. Eukaryotic initiation factor 4GII (eIF4GII), but not eIF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection
61. Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G
62. Initiation of protein synthesis from the A site of the ribosome