Primary hepatocytes of Tupaia belangeri as a potential model for hepatitis C virus infection

Journal of Clinical Investigation

Volumn 109, Issue 2, 2002, Pages 221-232

  Zhao, Xiping ^a   Tang, Zhen Ya ^a,c   Klumpp, Bettina ^a   Wolff Vorbeck, Guido ^a   Barth, Heidi ^a   Levy, Shoshana ^b   Von Weizsäcker, Fritz ^a   Blum, Hubert E ^a   Baumert, Thomas F ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OCHSNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD81 ANTIGEN; VIRUS GLYCOPROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONSENSUS SEQUENCE; CONTROLLED STUDY; EVOLUTION; HEPATITIS C; HEPATITIS C VIRUS; INSECTIVORE; LIVER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; RNA ANALYSIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TUPAIA BELANGERIA; VIRUS ADSORPTION; VIRUS LOAD;

EID: 0036156021     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0213011     Document Type: Article

References (49)

1. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
2. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
3. Pathogenesis, natural history, treatment, and prevention of hepatitis C
4. The prevalence of hepatitis C virus infection in the United States 1988-1994
5. Clinical outcomes after transfusion-associated hepatitis C
6. Replication of hepatitis C virus
7. Flaviviridae: The viruses and their replication
8. The molecular virology of hepatitis C
9. Binding of hepatitis C virus to CD81
10. Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81
11. CD81 (TAPA-1): A molecule involved in signal transduction and cell adhesion in the immune system
12. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
13. Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization
14. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
15. Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee
16. Transmission of hepatitis C virus infection to tree shrews
17. Experimental infection of Tupaia belangeri (tree shrews) with herpes simplex virus types 1 and 2
18. Mutations in the p53 tumor suppressor gene in tree shrew hepatocellular carcinoma associated with hepatitis B virus infection and intake of aflatoxin B1
19. Experimental infection of adult Tupia belangeri yunalis with human rotavirus
20. Hepatitis B virus infection of Tupia hepatocytes in vitro and in vivo
21. Human hepatitis B virus and hepatocellular carcinoma. I. Experimental infection of tree shrews with hepatitis B virus
22. Efficient infection of primary Tupaia hepatocytes with purified human and woolly monkey hepatitis B virus
23. Hepatitis B virus (HBV) virion and covalently closed circular DNA formation in primary Tupaia hepatocytes and human hepatoma cell lines upon HBV genome cransduccion with replication-defective adenovirus vectors
24. The hepatitis C virus structural proteins assemble into virus-like particles in insect cells
25. Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate
26. Antibodies against hepatitis-C viruslike particles and viral clearance in acute and chronic hepatitis C
27. Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprorein E2
28. Two core promotor mutations identified in a hepatitis B virus strain associated with Fulminant hepatitis result in enhanced viral replication
29. Ethanol-induced inhibition of leukotriene degradation by co-oxidation
30. Nucleotide sequence and mutation rate of the H strain of hepatitis C virus
31. Demonstration of in vitro infection of chimpanzee hepatocytes with hepatitis C virus using strand-specific RT/PCR
32. Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants
33. Avoiding False positives with PCR
34. Fluctuation of hepatitis C quasispecies in persistent infection and interferon treatment revealed by single-strand conformation polymorphism analysis
35. Naturally occurring mutations define a novel function of the hepatitis B virus core promotor in core protein expression
36. A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: Cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells
37. Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: An endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates
38. Structure-function analysis of hepatitis C virus envelope-CD81 binding
39. Long-term follow-up of chimpanzees inoculated with the first infectious clone For hepatitis C virus
40. Primary Tupaia hepatocytes as a model to study hepatitis C virus infection and replication
41. Efficient initiation of HCV RNA replication in cell culture
42. Dynamic analysis of hepatitis C virus replication and quasispecies selection in long-term cultures of adult human hepatocytes infected in vitro
43. Permissiveness of human biliary epithelial cells to infection by hepatitis C virus
44. Evidence For in vitro replication of hepatitis C virus genome in a human T-cell line
45. Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co-stimulatory signal For human T cells
46. Functional characterization of intracellular and secreted forms of a truncated hepatitis C virus E2 glycoprotein
47. Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor
48. Binding of hepatitis C virus E2 glycoprotein to CD81 does not correlate with species permissiveness to infection
49. Hepatitis C virus envelope protein E2 binds to CD81 oftamarins