Identification and characterization of an RNA-dependent RNA polymerase activity within the nonstructural protein 5B region of bovine viral diarrhea virus

Journal of Virology

Volumn 72, Issue 11, 1998, Pages 9365-9369

  Zhong, Weidong ^a   Gutshall, Lester L ^a   Del Vecchio, Alfred M ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED RNA POLYMERASE; VIRUS PROTEIN;

ARTICLE; BOVINE DIARRHEA VIRUS; ENZYME MECHANISM; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

EID: 0031686765     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.11.9365-9369.1998     Document Type: Article

References (22)

1. Baker, J. C. 1987. Bovine viral diarrhea virus: a review. J. Am. Vet. Med. Assoc. 11:1449-1458.
2. Bartenschlager, R., M. Junker-Niepmann, and H. Schaller. 1990. The P gene product of hepatitis B virus is required as a structural component for genomic RNA encapsidation. J. Virol. 64:5324-5332.
3. Behrens, S.-E., L. Tomei, and R. De Francesco. 1996. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J. 15:12-22.
4. Collett, M. S., R. Larson, C. Gold, D. Strick, D. K. Anderson, and A. F. Purchio. 1988. Molecular cloning and nucleotide sequence of the pestivirus bovine viral diarrhea virus. Virology 165:191-199.
5. Collett, M. S., R. Larson, S. Belzer, and E. Retzel. 1988. Proteins encoded by bovine viral diarrhea virus: the genome organization of a pestivirus. Virology 165:200-208.
6. Collett, M. S. 1992. Molecular genetics of pestiviruses. Comp. Immun. Microbiol. Infect. Dis. 15:145-154.
7. De Francesco, R., S.-E. Behrens, L. Tomei, S. Altamura, and J. Jiricny. 1996. RNA-dependent RNA polymerase of hepatitis C virus. Methods Enzymol. 275:58-67.
8. Deng, R., and K. V. Brock. 1993. 5′ and 3′ untranslated regions of pestivirus genome: primary and secondary structure analysis. Nucleic Acids Res. 21: 1949-1957.
9. Donis, R. O. 1995. Molecular biology of bovine viral diarrhea virus and its interactions with the host. Vet. Clin. N. Am. Food Anim. Pract. 11:393-423.
10. Elbers, K., N. Tautz, P. Becher, T. Rumenapf, and H.-J. Thiel. 1996. Processing in the pestivirus E2-NS2 region: identification of the nonstructural proteins p7 and E2p7. J. Virol. 70:4131-4135.
11. Lohmann, V., F. Korner, U. Herian, and R. Bartenschlager. 1997. Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motif essential for enzymatic activity. J. Virol. 71:8416-8428.
12. Meyers, G., T. Rumenapf, and H.-J. Thiel. 1989. Molecular cloning and nucleotide sequence of the genome of hog cholera virus. Virology 171:555-567.
13. Meyers, G., and H.-J. Thiel. 1996. Molecular characterization of pestiviruses. Adv. Virus Res. 47:53-118.
14. Moennig, V., and P. G. Plagemann. 1992. The pestiviruses. Adv. Virus Res. 41:53-98.
15. Petric, M., R. H. Yolken, E. J. Dubovi, M. A. Wiskerchen, and M. S. Collett. 1992. Baculovirus expression of pestivirus non-structural proteins. J. Gen. Virol. 73:1867-1871.
16. Rice, C. M. 1996. Flaviviridae: the viruses and their replication, p. 931-959. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed., vol. 1. Lippincott-Raven Press, Philadelphia, Pa.
17. Rumenapf, T., G. Unger, J. H. Strauss, and H.-J. Thiel. 1993. Processing of the envelope glycoproteins of pestiviruses. J. Virol. 67:3288-3295.
18. Stark, R., G. Meyers, T. Rumenapf, and H.-J. Thiel. 1993. Processing of pestivirus polyprotein: cleavage site between autoprotease and nucleocapsid protein of classical swine fever virus. J. Virol. 67:7088-7095.
19. Tautz, N., K. Elbers, D. Stoll, G. Meyers, and H.-J. Thiel. 1997. Serine protease of pestiviruses: determination of cleavage sites. J. Virol. 71:5415-5422.
20. Thiel, H. J., G. W. Plagemann, and V. Moennig. 1996. Pestiviruses, p. 1059-1073. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed., vol. 1. Lippincott-Raven Press, Philadelphia, Pa.
21. Vassilev, V. B., M. S. Collett, and R. O. Donis. 1997. Authentic and chimeric full-length genomic cDNA clones of bovine viral diarrhea virus that yield infectious transcripts. J. Virol. 71:471-478.
22. Xu, J., E. Mendez, P. R. Caron, C. Lin, M. A. Murcko, M. C. Collett, and C. M. Rice. 1997. Bovine viral diarrhea virus: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication. J. Virol. 71:5312-5322.