Autoimmune diabetes in HLA-DR3/DQ8 transgenic mice expressing the co-stimulatory molecule B7-1 in the β cells of islets of Langerhans

International Immunology

Volumn 15, Issue 9, 2003, Pages 1035-1044

  Rajagopalan, Govindarajan ^a   Kudva, Yogish C ^a   Chen, Lieping ^a   Wen, Li ^b   David, Chella S ^a  

^a MAYO CLINIC   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmunity; Diabetes; HLA DQ8; HLA DR3; Transgenic knockout

Indexed keywords

B7 ANTIGEN; CD137 ANTIGEN; CYTOTOXIN; HLA ANTIGEN CLASS 2; HLA DR3 ANTIGEN; INTERLEUKIN 2 RECEPTOR; STREPTOZOCIN; SUPERANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN FUNCTION; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENETIC PREDISPOSITION; HUMAN; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE DEPLETION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE; WHOLE BODY RADIATION;

ANIMALS; ANTIGENS, CD80; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; HLA-DQ ANTIGENS; HLA-DR3 ANTIGEN; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; STREPTOZOCIN; T-LYMPHOCYTES;

EID: 0042353612     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg103     Document Type: Review

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