-
1
-
-
0029954214
-
Insulin-dependent diabetes mellitus
-
Tisch R, McDevitt H: Insulin-dependent diabetes mellitus. Cell 85:291-297, 1996
-
(1996)
Cell
, vol.85
, pp. 291-297
-
-
Tisch, R.1
McDevitt, H.2
-
2
-
-
0036164731
-
Genetic linkage and association studies of type I diabetes: Challenges and rewards
-
Field LL: Genetic linkage and association studies of type I diabetes: challenges and rewards. Diabetologia 45:21-35, 2002
-
(2002)
Diabetologia
, vol.45
, pp. 21-35
-
-
Field, L.L.1
-
3
-
-
0036152560
-
T-cell education in autoimmune diabetes: Teachers and students
-
Rosmalen JG, van Ewijk W, Leenen PJ: T-cell education in autoimmune diabetes: teachers and students. Trends Immunol 23:40-46, 2002
-
(2002)
Trends Immunol
, vol.23
, pp. 40-46
-
-
Rosmalen, J.G.1
Van Ewijk, W.2
Leenen, P.J.3
-
4
-
-
0032701409
-
The role of CD4 vs. CD8 T cells in IDDM
-
Wong FS, Janeway CA Jr: The role of CD4 vs. CD8 T cells in IDDM. J Autoimmun 13:290-295, 1999
-
(1999)
J Autoimmun
, vol.13
, pp. 290-295
-
-
Wong, F.S.1
Janeway C.A., Jr.2
-
5
-
-
0032776148
-
HLA class II transgenic mice as models of human diseases
-
Taneja V, David CS: HLA class II transgenic mice as models of human diseases. Immunol Rev 169:67-79, 1999
-
(1999)
Immunol Rev
, vol.169
, pp. 67-79
-
-
Taneja, V.1
David, C.S.2
-
6
-
-
0031937692
-
Animal models of type I (insulin-dependent) diabetes mellitus
-
Cheta D: Animal models of type I (insulin-dependent) diabetes mellitus. J Pediatr Endocrinol Metab 11:11-19, 1998
-
(1998)
J Pediatr Endocrinol Metab
, vol.11
, pp. 11-19
-
-
Cheta, D.1
-
7
-
-
0035380479
-
Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes
-
Lee KH, Wucherpfennig KW, Wiley DC: Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes. Nat Immunol 2:501-507, 2001
-
(2001)
Nat Immunol
, vol.2
, pp. 501-507
-
-
Lee, K.H.1
Wucherpfennig, K.W.2
Wiley, D.C.3
-
8
-
-
0036533658
-
Human DQ8 can substitute for murine I-A(g7) in the selection of diabetogenic T cells restricted to I-A(g71)
-
Wen L, Wong FS, Sherwin R, Mora C: Human DQ8 can substitute for murine I-A(g7) in the selection of diabetogenic T cells restricted to I-A(g71). J Immunol 168:3635-3640, 2002
-
(2002)
J Immunol
, vol.168
, pp. 3635-3640
-
-
Wen, L.1
Wong, F.S.2
Sherwin, R.3
Mora, C.4
-
9
-
-
0034079792
-
Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice
-
Abraham RS, Kudva YC, Wilson SB, Strominger JL, David CS: Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice. Diabetes 49:548-554, 2000
-
(2000)
Diabetes
, vol.49
, pp. 548-554
-
-
Abraham, R.S.1
Kudva, Y.C.2
Wilson, S.B.3
Strominger, J.L.4
David, C.S.5
-
10
-
-
0035863759
-
Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model
-
Abraham RS, Wen L, Marietta EV, David CS: Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model. J Immunol 166:1370-1379, 2001
-
(2001)
J Immunol
, vol.166
, pp. 1370-1379
-
-
Abraham, R.S.1
Wen, L.2
Marietta, E.V.3
David, C.S.4
-
11
-
-
0034598313
-
In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes
-
Wen L, Wong FS, Tang J, Chen NY, Altieri M, David C, Flavell R, Sherwin R: In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes. J Exp Med 191:97-104, 2000
-
(2000)
J Exp Med
, vol.191
, pp. 97-104
-
-
Wen, L.1
Wong, F.S.2
Tang, J.3
Chen, N.Y.4
Altieri, M.5
David, C.6
Flavell, R.7
Sherwin, R.8
-
12
-
-
0035061420
-
The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model
-
Wen L, Chen NY, Tang J, Sherwin R, Wong FS: The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model. J Clin Invest 107:871-880, 2001
-
(2001)
J Clin Invest
, vol.107
, pp. 871-880
-
-
Wen, L.1
Chen, N.Y.2
Tang, J.3
Sherwin, R.4
Wong, F.S.5
-
13
-
-
0036828265
-
Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II
-
Kudva YC, Rajagopalan G, Raju R, Abraham RS, Smart M, Hansen J, David CS: Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II. Hum Immunol 63:987-999, 2002
-
(2002)
Hum Immunol
, vol.63
, pp. 987-999
-
-
Kudva, Y.C.1
Rajagopalan, G.2
Raju, R.3
Abraham, R.S.4
Smart, M.5
Hansen, J.6
David, C.S.7
-
14
-
-
18244422579
-
Islet cell autoimmunity in NOD mice transgenic for HLA-DQ8 and lacking I-Ag7
-
Raju R, Munn SR, Majoribanks C, David CS: Islet cell autoimmunity in NOD mice transgenic for HLA-DQ8 and lacking I-Ag7. Transplant Proc 30:561, 1998
-
(1998)
Transplant Proc
, vol.30
, pp. 561
-
-
Raju, R.1
Munn, S.R.2
Majoribanks, C.3
David, C.S.4
-
15
-
-
0027207669
-
Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes: Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice
-
Picarella DE, Kratz A, Li CB, Ruddle NH, Flavell RA: Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes: distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice. J Immunol 150:4136-4150, 1993
-
(1993)
J Immunol
, vol.150
, pp. 4136-4150
-
-
Picarella, D.E.1
Kratz, A.2
Li, C.B.3
Ruddle, N.H.4
Flavell, R.A.5
-
16
-
-
0034677105
-
Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells
-
Green EA, Wong FS, Eshima K, Mora C, Flavell RA: Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells. J Exp Med 191:225-238, 2000
-
(2000)
J Exp Med
, vol.191
, pp. 225-238
-
-
Green, E.A.1
Wong, F.S.2
Eshima, K.3
Mora, C.4
Flavell, R.A.5
-
17
-
-
0032813549
-
Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice
-
Green EA, Flavell RA: Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice. Immunol Rev 169:11-22, 1999
-
(1999)
Immunol Rev
, vol.169
, pp. 11-22
-
-
Green, E.A.1
Flavell, R.A.2
-
18
-
-
0028922437
-
Genetic control of autoimmune diabetes in the NOD mouse
-
Wicker LS, Todd JA, Peterson LB: Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol 13:179-200, 1995
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 179-200
-
-
Wicker, L.S.1
Todd, J.A.2
Peterson, L.B.3
-
19
-
-
0026091380
-
Mice lacking MHC class II molecules
-
Cosgrove D, Gray D, Dierich A, Kaufman J, Lemeur M, Benoist C, Mathis D: Mice lacking MHC class II molecules. Cell 66:1051-1066, 1991
-
(1991)
Cell
, vol.66
, pp. 1051-1066
-
-
Cosgrove, D.1
Gray, D.2
Dierich, A.3
Kaufman, J.4
Lemeur, M.5
Benoist, C.6
Mathis, D.7
-
20
-
-
0020690737
-
Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes
-
Mathis DJ, Benoist C, Williams VE 2nd, Kanter M, McDevitt HO: Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes. Proc Natl Acad Sci U S A 80:273-277, 1983
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 273-277
-
-
Mathis, D.J.1
Benoist, C.2
Williams V.E. II3
Kanter, M.4
McDevitt, H.O.5
-
21
-
-
0026474808
-
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes
-
Higuchi Y, Herrera P, Muniesa P, Huarte J, Belin D, Ohashi P, Aichele P, Orci L, Vassalli JD, Vassalli P: Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med 176:1719-1731, 1992
-
(1992)
J Exp Med
, vol.176
, pp. 1719-1731
-
-
Higuchi, Y.1
Herrera, P.2
Muniesa, P.3
Huarte, J.4
Belin, D.5
Ohashi, P.6
Aichele, P.7
Orci, L.8
Vassalli, J.D.9
Vassalli, P.10
-
22
-
-
0033561560
-
Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: Studies using NOD/CIITA-deficient mice
-
Mora C, Wong FS, Chang CH, Flavell RA: Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice. J Immunol 162:4576-4588, 1999
-
(1999)
J Immunol
, vol.162
, pp. 4576-4588
-
-
Mora, C.1
Wong, F.S.2
Chang, C.H.3
Flavell, R.A.4
-
23
-
-
0031704329
-
Mice lacking the transcription factor CIITA: A second look
-
Williams GS, Malin M, Vremec D, Chang CH, Boyd R, Benoist C, Mathis D: Mice lacking the transcription factor CIITA: a second look. Int Immunol 10:1957-1967, 1998
-
(1998)
Int Immunol
, vol.10
, pp. 1957-1967
-
-
Williams, G.S.1
Malin, M.2
Vremec, D.3
Chang, C.H.4
Boyd, R.5
Benoist, C.6
Mathis, D.7
-
24
-
-
0035185411
-
Control of T-cell activation by CD4+ CD25+ suppressor T cells
-
Shevach EM, McHugh RS, Piccirillo CA, Thornton AM: Control of T-cell activation by CD4+ CD25+ suppressor T cells. Immunol Rev 182:58-67, 2001
-
(2001)
Immunol Rev
, vol.182
, pp. 58-67
-
-
Shevach, E.M.1
McHugh, R.S.2
Piccirillo, C.A.3
Thornton, A.M.4
-
25
-
-
0035920510
-
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
-
Bensinger SJ, Bandeira A, Jordan MS, Caton AJ, Laufer TM: Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J Exp Med 194:427-438, 2001
-
(2001)
J Exp Med
, vol.194
, pp. 427-438
-
-
Bensinger, S.J.1
Bandeira, A.2
Jordan, M.S.3
Caton, A.J.4
Laufer, T.M.5
-
26
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon B, Lenschow DJ, Rhee L, Ashourian N, Singh B, Sharpe A, Bluestone JA: B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12:431-440, 2000
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
Ashourian, N.4
Singh, B.5
Sharpe, A.6
Bluestone, J.A.7
-
27
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
Kukreja A, Cost G, Marker J, Zhang C, Sun Z, Lin-Su K, Ten S, Sanz M, Exley M, Wilson B, Porcelli S, Maclaren N: Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest 109:131-140, 2002
-
(2002)
J Clin Invest
, vol.109
, pp. 131-140
-
-
Kukreja, A.1
Cost, G.2
Marker, J.3
Zhang, C.4
Sun, Z.5
Lin-Su, K.6
Ten, S.7
Sanz, M.8
Exley, M.9
Wilson, B.10
Porcelli, S.11
Maclaren, N.12
-
28
-
-
0036196305
-
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: Highly potent regulators of diabetes that require TRANCE-RANK signals
-
Green EA, Choi Y, Flavell RA: Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity 16:183-191, 2002
-
(2002)
Immunity
, vol.16
, pp. 183-191
-
-
Green, E.A.1
Choi, Y.2
Flavell, R.A.3
-
29
-
-
0037097503
-
Depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease
-
McHugh RS, Shevach EM: Depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease. J Immunol 168:5979-5983, 2002
-
(2002)
J Immunol
, vol.168
, pp. 5979-5983
-
-
McHugh, R.S.1
Shevach, E.M.2
-
30
-
-
0037136283
-
CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer
-
Tarbell KV, Lee M, Ranheim E, Chao CC, Sanna M, Kim SK, Dickie P, Teyton L, Davis M, McDevitt H: CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer. J Exp Med 196:481-492, 2002
-
(2002)
J Exp Med
, vol.196
, pp. 481-492
-
-
Tarbell, K.V.1
Lee, M.2
Ranheim, E.3
Chao, C.C.4
Sanna, M.5
Kim, S.K.6
Dickie, P.7
Teyton, L.8
Davis, M.9
McDevitt, H.10
-
31
-
-
0036604283
-
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance
-
Graca L, Thompson S, Lin CY, Adams E, Cobbold SP, Waldmann H: Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol 168:5558-5565, 2002
-
(2002)
J Immunol
, vol.168
, pp. 5558-5565
-
-
Graca, L.1
Thompson, S.2
Lin, C.Y.3
Adams, E.4
Cobbold, S.P.5
Waldmann, H.6
-
32
-
-
0034965185
-
Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: Evidence for two distinct regulatory mechanisms
-
Wolf M, Schimpl A, Hunig T: Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms. Eur J Immunol 31:1637-1645, 2001
-
(2001)
Eur J Immunol
, vol.31
, pp. 1637-1645
-
-
Wolf, M.1
Schimpl, A.2
Hunig, T.3
-
33
-
-
0033529820
-
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes
-
Anderson B, Park BJ, Verdaguer J, Amrani A, Santamaria P: Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes. Proc Natl Acad Sci U S A 96:9311-9316, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9311-9316
-
-
Anderson, B.1
Park, B.J.2
Verdaguer, J.3
Amrani, A.4
Santamaria, P.5
-
34
-
-
13344294394
-
CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells
-
Wong FS, Visintin I, Wen L, Flavell RA, Janeway CA Jr: CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. J Exp Med 183:67-76, 1996
-
(1996)
J Exp Med
, vol.183
, pp. 67-76
-
-
Wong, F.S.1
Visintin, I.2
Wen, L.3
Flavell, R.A.4
Janeway C.A., Jr.5
-
35
-
-
0035424204
-
MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity
-
Quinn A, McInerney MF, Sercarz EE: MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity. J Immunol 167:1748-1757, 2001
-
(2001)
J Immunol
, vol.167
, pp. 1748-1757
-
-
Quinn, A.1
McInerney, M.F.2
Sercarz, E.E.3
-
36
-
-
0032214715
-
Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
-
Green EA, Eynon EE, Flavell RA: Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity 9:733-743, 1998
-
(1998)
Immunity
, vol.9
, pp. 733-743
-
-
Green, E.A.1
Eynon, E.E.2
Flavell, R.A.3
-
37
-
-
0033526068
-
In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha
-
Pakala SV, Chivetta M, Kelly CB, Katz JD: In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha. J Exp Med 189:1053-1062, 1999
-
(1999)
J Exp Med
, vol.189
, pp. 1053-1062
-
-
Pakala, S.V.1
Chivetta, M.2
Kelly, C.B.3
Katz, J.D.4
-
38
-
-
0035856952
-
Beta-cell death during progression to diabetes
-
Mathis D, Vence L, Benoist C: Beta-cell death during progression to diabetes. Nature 414:792-798, 2001
-
(2001)
Nature
, vol.414
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
39
-
-
0036467353
-
In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes
-
Zhang Y, O'Brien B, Trudeau J, Tan R, Santamaria P, Dutz JP: In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes. J Immunol 168:1466-1472, 2002
-
(2002)
J Immunol
, vol.168
, pp. 1466-1472
-
-
Zhang, Y.1
O'Brien, B.2
Trudeau, J.3
Tan, R.4
Santamaria, P.5
Dutz, J.P.6
|