Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4+ T cells from human DQ transgenic mice

Journal of Clinical Investigation

Volumn 102, Issue 5, 1998, Pages 947-957

  Wen, Li ^a   Wong, F Susan ^a   Burkly, Linda ^b   Altieri, Martha ^a   Mamalaki, C ^c   Kioussis, Dimitris ^c   Flavell, Richard A ^a   Sherwin, Robert S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BIOGEN   (United States)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Glutamic acid decarboxylase; HLA DQ8; T cells; Transgenic mice

Indexed keywords

CD8 ANTIGEN; FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE; HLA DQ ANTIGEN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CYTOKINE PRODUCTION; GERMINAL CENTER; HELPER CELL; HLA SYSTEM; INSULITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0032167433     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2723     Document Type: Article

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