Estimation of genetic risk for type 1 diabetes

American Journal of Medical Genetics - Seminars in Medical Genetics

Volumn 115, Issue 1, 2002, Pages 30-36

  Ilonen, Jorma ^a   Sjöroos, Minna ^b   Knip, Mikael ^c   Veijola, Riitta ^d   Simell, Olli ^a   Åkerblom, Hans K ^c   Paschou, Peri ^e   Bozas, Evangelos ^e   Havarani, Beatrice ^e   Malamitsi Puchner, Ariadne ^e   Thymelli, Joanna ^e   Vazeou, Andriani ^f   Bartsocas, Christos S ^e  

^a UNIVERSITY OF TURKU   (Finland)

^b PerkinElmer Finland Oy   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF OULU   (Finland)

^e UNIVERSITY OF ATHENS   (Greece)

^f NONE

Author keywords

Genetic risk; Genetic screening; HLA genes; Risk estimation; Type 1 diabetes

Indexed keywords

GENE PRODUCT; HLA DQ ANTIGEN; HLA DR ANTIGEN; HLA DR4 ANTIGEN;

ALLELE; FINLAND; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; GREECE; HAPLOTYPE; HLA SYSTEM; INSULIN DEPENDENT DIABETES MELLITUS; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; GENETIC MARKER; GENETICS; HISTOCOMPATIBILITY TEST; HUMAN; METHODOLOGY;

DIABETES MELLITUS, INSULIN-DEPENDENT; GENETIC MARKERS; GENOTYPE; HISTOCOMPATIBILITY TESTING; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMAN; RISK ASSESSMENT; SUPPORT, NON-U.S. GOV'T; DIABETES MELLITUS, TYPE 1; HUMANS;

EID: 0036072188     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajmg.10341     Document Type: Review

References (20)

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6. The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-Class II gene
7. Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-Eα-chain
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9. The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302
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15. Invited anniversary review: HLA associated diseases
16. DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1 *0501-DQB1*0201 genotype
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