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Volumn 235, Issue , 2001, Pages 116-129

Ageing and cancer: The telomere and telomerase connection

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

EID: 0035221480     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article
Times cited : (33)

References (33)
  • 1
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • Blasco MA, Lee HW, Hande MP et al 1997 Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91:25-34
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.A.1    Lee, H.W.2    Hande, M.P.3
  • 2
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • Bodnar AG, Ouellette M, Frolkis M et al 1998 Extension of life-span by introduction of telomerase into normal human cells. Science 279:349-352
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1    Ouellette, M.2    Frolkis, M.3
  • 3
    • 0033553516 scopus 로고    scopus 로고
    • p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Chin L, Artandi SE, Shen Q et al 1999 p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97:527-538
    • (1999) Cell , vol.97 , pp. 527-538
    • Chin, L.1    Artandi, S.E.2    Shen, Q.3
  • 4
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee XH, Basile G et al 1995 A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92:9363-9367
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.H.2    Basile, G.3
  • 5
    • 8944258925 scopus 로고    scopus 로고
    • Shortened telomeres in the expanded CD28, & CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
    • Effros RB, Allsopp R, Chiu CP et al 1996 Shortened telomeres in the expanded CD28, & CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 10:F17-F22
    • (1996) AIDS , vol.10
    • Effros, R.B.1    Allsopp, R.2    Chiu, C.P.3
  • 6
    • 0003293418 scopus 로고
    • On the nature and function expressivity of the law of human mortality and on a new mode of determining life contingencies
    • Gompertz B 1825 On the nature and function expressivity of the law of human mortality and on a new mode of determining life contingencies. Phil Trans R Soc Lond 115:513-585
    • (1825) Phil Trans R Soc Lond , vol.115 , pp. 513-585
    • Gompertz, B.1
  • 7
    • 0000146723 scopus 로고    scopus 로고
    • Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse
    • Greenberg RA, Chin L, Femino A et al 1999 Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 97:515-525
    • (1999) Cell , vol.97 , pp. 515-525
    • Greenberg, R.A.1    Chin, L.2    Femino, A.3
  • 8
    • 0032427906 scopus 로고    scopus 로고
    • How might replicative senescence contribute to human ageing?
    • Faragher RGA, Kipling D 1998 How might replicative senescence contribute to human ageing? Bioessays 20:985-991
    • (1998) Bioessays , vol.20 , pp. 985-991
    • Faragher, R.G.A.1    Kipling, D.2
  • 10
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA 2000 The hallmarks of cancer. Cell 100:57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 11
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • Harley CB 1991 Telomere loss: mitotic clock or genetic time bomb? Mutat Res 256:271-282
    • (1991) Mutat Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 12
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW 1990 Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 13
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS 1961 The serial cultivation of human diploid cell strains. Exp Cell Res 25:585-621
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 14
    • 0032923742 scopus 로고    scopus 로고
    • Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
    • Jiang XR, Jimenez G, Chang E et al 1999 Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 21:111-114
    • (1999) Nat Genet , vol.21 , pp. 111-114
    • Jiang, X.R.1    Jimenez, G.2    Chang, E.3
  • 15
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR et al 1994 Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 16
    • 0030668787 scopus 로고    scopus 로고
    • Mammalian telomerase: Catalytic subunit and knockout mice
    • Kipling D 1997 Mammalian telomerase: catalytic subunit and knockout mice. Hum Mol Genet 6:1999-2004
    • (1997) Hum Mol Genet , vol.6 , pp. 1999-2004
    • Kipling, D.1
  • 17
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • Kipling D, Cooke HJ 1990 Hypervariable ultra-long telomeres in mice. Nature 347:400-402
    • (1990) Nature , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 18
    • 0030707880 scopus 로고    scopus 로고
    • Progeroid syndromes: Probing the molecular basis of aging?
    • Kipling D, Faragher RGA 1997 Progeroid syndromes: probing the molecular basis of aging? Mol Pathol 50:234-241
    • (1997) Mol Pathol , vol.50 , pp. 234-241
    • Kipling, D.1    Faragher, R.G.A.2
  • 19
    • 0030447280 scopus 로고    scopus 로고
    • Human senescence
    • Kirkwood TBL 1996 Human senescence. Bioessays 19:1009-1016
    • (1996) Bioessays , vol.19 , pp. 1009-1016
    • Kirkwood, T.B.L.1
  • 20
    • 0014816132 scopus 로고
    • Replicative life-span of cultivated human cells. Effect of donor's age, tissue, and genotype
    • Martin GM, Sprague CA, Epstein CJ 1970 Replicative life-span of cultivated human cells. Effect of donor's age, tissue, and genotype. Lab Invest 23:86-92
    • (1970) Lab Invest , vol.23 , pp. 86-92
    • Martin, G.M.1    Sprague, C.A.2    Epstein, C.J.3
  • 21
    • 0032924343 scopus 로고    scopus 로고
    • Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
    • Morales CP, Holt SE, Ouellette MM et al 1999 Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nat Genet 21:115-118
    • (1999) Nat Genet , vol.21 , pp. 115-118
    • Morales, C.P.1    Holt, S.E.2    Ouellette, M.M.3
  • 22
    • 0034639725 scopus 로고    scopus 로고
    • The establishment of telomerase-immortalized cell lines representing human chromosome instability syndromes
    • Ouellette MM, McDaniel LD, Wright WE, Shay JW, Shultz RA 2000 The establishment of telomerase-immortalized cell lines representing human chromosome instability syndromes. Hum Mol Genet 9:403-411
    • (2000) Hum Mol Genet , vol.9 , pp. 403-411
    • Ouellette, M.M.1    McDaniel, L.D.2    Wright, W.E.3    Shay, J.W.4    Shultz, R.A.5
  • 23
    • 0030743137 scopus 로고    scopus 로고
    • Cell aging in vivo and in vitro
    • Rubin H 1997 Cell aging in vivo and in vitro. Mech Ageing Dev 98:1-35
    • (1997) Mech Ageing Dev , vol.98 , pp. 1-35
    • Rubin, H.1
  • 24
    • 0033525558 scopus 로고    scopus 로고
    • Longevity, stress response, and cancer in aging telomerase-deficient mice
    • Rudolph KL, Chang S, Lee HW et al 1999 Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96:701-712
    • (1999) Cell , vol.96 , pp. 701-712
    • Rudolph, K.L.1    Chang, S.2    Lee, H.W.3
  • 26
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase in human cancer
    • Shay JW, Bacchetti S 1997 A survey of telomerase in human cancer. Eur J Cancer 33:787-791
    • (1997) Eur J Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 27
    • 0033986708 scopus 로고    scopus 로고
    • The use of telomerized cells for tissue engineering
    • Shay JW, Wright WE 2000 The use of telomerized cells for tissue engineering. Nat Biotechnol 18:22-23
    • (2000) Nat Biotechnol , vol.18 , pp. 22-23
    • Shay, J.W.1    Wright, W.E.2
  • 28
    • 0033989539 scopus 로고    scopus 로고
    • Formation of functional tissue from transplanted adrenocortical cells expressing telomerase reverse transcriptase
    • Thomas M, Yang LQ, Hornsby PJ 2000 Formation of functional tissue from transplanted adrenocortical cells expressing telomerase reverse transcriptase. Nat Biotechnol 18:39-42
    • (2000) Nat Biotechnol , vol.18 , pp. 39-42
    • Thomas, M.1    Yang, L.Q.2    Hornsby, P.J.3
  • 30
    • 0032567967 scopus 로고    scopus 로고
    • Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
    • Vaziri H, Benchimol S 1998 Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr Biol 8:279-282
    • (1998) Curr Biol , vol.8 , pp. 279-282
    • Vaziri, H.1    Benchimol, S.2
  • 31
    • 0028044767 scopus 로고
    • The cellular and molecular biology of skin aging
    • West MD 1994 The cellular and molecular biology of skin aging. Arch Dermatol 130:87-95
    • (1994) Arch Dermatol , vol.130 , pp. 87-95
    • West, M.D.1
  • 32
    • 0029962187 scopus 로고    scopus 로고
    • Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence
    • West MD, Shay JW, Wright WE, Linksken MHK 1996 Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence. Exp Gerontol 31:175-193
    • (1996) Exp Gerontol , vol.31 , pp. 175-193
    • West, M.D.1    Shay, J.W.2    Wright, W.E.3    Linksken, M.H.K.4
  • 33
    • 0031561327 scopus 로고    scopus 로고
    • Telomerase. Cancer and the knockout mouse
    • Wynford-Thomas D, Kipling D 1997 Telomerase. Cancer and the knockout mouse. Nature 389:551-552
    • (1997) Nature , vol.389 , pp. 551-552
    • Wynford-Thomas, D.1    Kipling, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.