Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D

Cell Death and Differentiation

Volumn 10, Issue 9, 2003, Pages 1090-1100

  Tardy, C ^a   Tyynela J ^b   Hasilik, A ^c   Levade, T ^a   Andrieu Abadie, N ^a  

^a CHU RANGUEIL   (France)

^b UNIVERSITY OF HELSINKI   (Finland)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Apoptosis; Cathepsin D; Ceramide; I cell disease; Lysosome

Indexed keywords

ACYLSPHINGOSINE DEACYLASE; ASPARTIC PROTEINASE; CASPASE; CATHEPSIN D; CERAMIDE; CYTARABINE; CYTOTOXIC AGENT; DOXORUBICIN; LYSOSOME ENZYME; PEPSTATIN; SPHINGOSINE; STAUROSPORINE; TUMOR NECROSIS FACTOR ALPHA; VINBLASTINE;

ANIMAL CELL; APOPTOSIS; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; LYSOSOME; MISSENSE MUTATION; MUCOLIPIDOSIS TYPE 2; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SHEEP;

AMIDOHYDROLASES; ANIMALS; APOPTOSIS; CASPASES; CATALYTIC DOMAIN; CATHEPSIN D; CATHEPSINS; CELLS, CULTURED; CERAMIDES; DOXORUBICIN; FIBROBLASTS; HUMANS; LYSOSOMES; MUCOLIPIDOSES; MUTATION, MISSENSE; PEPSTATINS; PROTEASE INHIBITORS; PROTEIN TRANSPORT; SHEEP;

ANIMALIA; OVIS; OVIS ARIES;

EID: 0041912315     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401272     Document Type: Review

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