Endosomal-lysosomal proteolysis mediates death signalling by TNFα, not by etoposide, in L929 fibrosarcoma cells: Evidence for an active role of cathepsin D

Biological Chemistry

Volumn 383, Issue 7-8, 2002, Pages 1237-1248

  Démoz, Marina ^a   Castino, Roberta ^a   Cesaro, Patrizia ^a   Baccino, Fancesco M ^a   Bonelli, Gabriella ^a   Isidoro, Ciro ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Apoptosis; Cathepsins; Cytokine; Etoposide (VP16); Lysosomes

Indexed keywords

CATHEPSIN B; CATHEPSIN D; CYSTEINE PROTEINASE INHIBITOR; CYTOKINE; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; LEUPEPTIN; MEMBRANE RECEPTOR; PEPSTATIN; SERINE PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; PROTEINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL PROTECTION; CELL STIMULATION; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; ENDOSOME; ENZYME LOCALIZATION; FIBROSARCOMA; IN VITRO STUDY; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; PATHOLOGY; PHYSIOLOGY;

ANIMALIA;

ANIMALS; APOPTOSIS; CATHEPSIN B; CATHEPSIN D; ENDOPEPTIDASES; ENDOSOMES; ETOPOSIDE; FIBROSARCOMA; LEUPEPTINS; LYSOSOMES; MICE; PEPSTATINS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036660887     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.137     Document Type: Article

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