메뉴 건너뛰기




Volumn 30, Issue 1, 1999, Pages 71-88

Cathepsins as effector proteases in hepatocyte apoptosis

Author keywords

Bile salts; Cathepsin B; Cathepsin D, Hepatocellular carcinoma; Topoisomerase inhibitors

Indexed keywords

BILE ACID; CAMPTOTHECIN; CATHEPSIN B; CATHEPSIN D; COMPLEMENTARY DNA; PEPSTATIN; PROTEINASE; PROTEINASE INHIBITOR; STREPTOMYCES PEPSIN INHIBITOR;

EID: 0032601582     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02737885     Document Type: Article
Times cited : (94)

References (43)
  • 1
    • 0015117787 scopus 로고
    • Shrinkage necrosis: A distinct mode of cellular death
    • Kerr, J. F. R. (1971) Shrinkage necrosis: a distinct mode of cellular death. J. Pathol. 105, 13-20.
    • (1971) J. Pathol. , vol.105 , pp. 13-20
    • Kerr, J.F.R.1
  • 2
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
    • Kerr, J. F. R., Wyllie, A. H., and Currie, A. R. (1972) Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 3
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie, A. H., Kerr, J. F. R., and Currie, A. R. (1980) Cell death: the significance of apoptosis. Int. Rev. Cytol. 68, 251-306.
    • (1980) Int. Rev. Cytol. , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.F.R.2    Currie, A.R.3
  • 4
    • 0029995766 scopus 로고    scopus 로고
    • A license to kill
    • Fraser, A. and Evan, G. (1996) A license to kill. Cell 85, 781-784.
    • (1996) Cell , vol.85 , pp. 781-784
    • Fraser, A.1    Evan, G.2
  • 6
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in a Fas/APO-1- and TNF receptor-induced cell death
    • Boldin, M. P., Goncharov, T. M., Goltsev, Y. V., and Wallach, D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in a Fas/APO-1- and TNF receptor-induced cell death. Cell 85, 803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 8
    • 0029927422 scopus 로고    scopus 로고
    • The role of proteases during apoptosis
    • Patel, T., Gores, G. J., and Kaufmann, S. H. (1996) The role of proteases during apoptosis. FASEB J. 10, 587-597.
    • (1996) FASEB J. , vol.10 , pp. 587-597
    • Patel, T.1    Gores, G.J.2    Kaufmann, S.H.3
  • 9
    • 0029782494 scopus 로고    scopus 로고
    • Cathepsin D protease mediates programmed cell death induced by interferon-g, Fas/APO-1 and TNF-a
    • Deiss, L. P., Galinka, H., Berissi, H., Cohen, O., and Kimchi, A. (1996) Cathepsin D protease mediates programmed cell death induced by interferon-g, Fas/APO-1 and TNF-a. EMBO J. 15, 3861-3870.
    • (1996) EMBO J. , vol.15 , pp. 3861-3870
    • Deiss, L.P.1    Galinka, H.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 10
    • 0029959819 scopus 로고    scopus 로고
    • Differential suppression by protease inhibitors and cytokines of apoptosis induced by wild-type p53 and cytotoxic agents
    • Lotem, J. and Sachs, L. (1996) Differential suppression by protease inhibitors and cytokines of apoptosis induced by wild-type p53 and cytotoxic agents. Proc. Natl. Acad. Sci. USA 93, 12,507-12,512.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93
    • Lotem, J.1    Sachs, L.2
  • 12
    • 0028924890 scopus 로고
    • Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
    • Nitatori, T., Sato, N., Waguri, S., Karasawa, Y., Araki, H., Shibanai, K., Kominami, E., and Uchiyama, Y. (1995) Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci. 15, 1001-1011.
    • (1995) J. Neurosci. , vol.15 , pp. 1001-1011
    • Nitatori, T.1    Sato, N.2    Waguri, S.3    Karasawa, Y.4    Araki, H.5    Shibanai, K.6    Kominami, E.7    Uchiyama, Y.8
  • 13
    • 0030933682 scopus 로고    scopus 로고
    • A comparison of cathepsin B processing and distribution during neuronal death in rats following global ischemia or decapitation necrosis
    • Hill, I. E., Preston, E., Monette, R., and MacManus, J. P. (1997) A comparison of cathepsin B processing and distribution during neuronal death in rats following global ischemia or decapitation necrosis. Brain Res. 751, 206-216.
    • (1997) Brain Res. , vol.751 , pp. 206-216
    • Hill, I.E.1    Preston, E.2    Monette, R.3    MacManus, J.P.4
  • 14
    • 0029149444 scopus 로고
    • Apoptosis and heterophagy of medial edge epithelial cells of the secondary palatine shelves during fusion
    • Taniguchi, K., Sato, N., and Uchiyama, Y. (1995) Apoptosis and heterophagy of medial edge epithelial cells of the secondary palatine shelves during fusion. Arch. Histol. Cytol. 58, 191-203.
    • (1995) Arch. Histol. Cytol. , vol.58 , pp. 191-203
    • Taniguchi, K.1    Sato, N.2    Uchiyama, Y.3
  • 17
    • 0025247125 scopus 로고
    • Hepatic injury induced by bile salts: Correlation between biochemical and morphological events
    • Schumucker, D. L., Ohta, M., Kanai, S., Sato, Y., and Kitani, K. (1990) Hepatic injury induced by bile salts: correlation between biochemical and morphological events. Hepatology 12, 1216-1221.
    • (1990) Hepatology , vol.12 , pp. 1216-1221
    • Schumucker, D.L.1    Ohta, M.2    Kanai, S.3    Sato, Y.4    Kitani, K.5
  • 18
    • 0025876404 scopus 로고
    • A multicenter controlled trial of ursodiol for the treatment of primary biliary cirrhosis
    • Poupon, R., Balkan, B., Eschwege, E., and Poupon, P. (1991) A multicenter controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N. Engl. J. Med. 324, 1548-1554.
    • (1991) N. Engl. J. Med. , vol.324 , pp. 1548-1554
    • Poupon, R.1    Balkan, B.2    Eschwege, E.3    Poupon, P.4
  • 19
    • 0028135420 scopus 로고
    • Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in hepatocytes
    • Patel, T., Bronk, S. F., and Gores, G. J. (1994) Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in hepatocytes. J. Clin. Invest. 94, 2183-2192.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2183-2192
    • Patel, T.1    Bronk, S.F.2    Gores, G.J.3
  • 20
    • 0030861210 scopus 로고    scopus 로고
    • Hepatocytes in the bile duct ligated rat express Bcl-2: A potential mechanism to inhibit apoptosis by toxic bile salts
    • Kurosawa, H., Que, F. G., Roberts, L. R., Fesmier, P. J., and Gores, G. J. (1997) Hepatocytes in the bile duct ligated rat express Bcl-2: a potential mechanism to inhibit apoptosis by toxic bile salts. Am. J. Physiol. 272, G1587-G1593.
    • (1997) Am. J. Physiol. , vol.272
    • Kurosawa, H.1    Que, F.G.2    Roberts, L.R.3    Fesmier, P.J.4    Gores, G.J.5
  • 21
    • 0028911047 scopus 로고
    • Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes
    • Kwo, P., Patel, T., Bronk, S. F., and Gores, G. J. (1995) Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes. Am. J. Physiol. 268, G613-G621.
    • (1995) Am. J. Physiol. , vol.268
    • Kwo, P.1    Patel, T.2    Bronk, S.F.3    Gores, G.J.4
  • 23
    • 0029439443 scopus 로고
    • Proteinases 1: Lysosomal cysteine proteinases
    • Kirschke, H., Barrett, A. J., and Rawlings, N. D. (1995) Proteinases 1: Lysosomal cysteine proteinases. Prot. Profile 2, 1587-1591.
    • (1995) Prot. Profile , vol.2 , pp. 1587-1591
    • Kirschke, H.1    Barrett, A.J.2    Rawlings, N.D.3
  • 24
    • 0020621648 scopus 로고
    • Action of human liver cathepsin B on the oxidized insulin B chain
    • McKay, M. J., Offermann, M. K., Barrett, A. J., and Bond, J. S. (1983) Action of human liver cathepsin B on the oxidized insulin B chain. Biochem. J. 213, 467-471.
    • (1983) Biochem. J. , vol.213 , pp. 467-471
    • McKay, M.J.1    Offermann, M.K.2    Barrett, A.J.3    Bond, J.S.4
  • 25
    • 0022551752 scopus 로고
    • Interrelationship of active and latent secreted human cathepsin B precursors
    • Mort, J. S. and Recklies, A. D. (1986) Interrelationship of active and latent secreted human cathepsin B precursors. Biochem. J. 233, 57-63.
    • (1986) Biochem. J. , vol.233 , pp. 57-63
    • Mort, J.S.1    Recklies, A.D.2
  • 26
    • 0028998783 scopus 로고
    • Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D
    • Authier, F., Mort, J. S., Bell, A. W., Posner, B. I., and Bergeron, J. J. (1995) Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D. J. Biol. Chem. 270, 15,798-15,807.
    • (1995) J. Biol. Chem. , vol.270
    • Authier, F.1    Mort, J.S.2    Bell, A.W.3    Posner, B.I.4    Bergeron, J.J.5
  • 27
    • 0028341492 scopus 로고
    • Cathepsin B activity in human lung tumor cell lines: Ultrastructural localization, pH sensitivity, and inhibitor status at the cellular level
    • Spiess, E., Bruning, A., Gack, S., Ulbricht, B., Spring, H., Trefz, G., and Ebert, W. (1994) Cathepsin B activity in human lung tumor cell lines: ultrastructural localization, pH sensitivity, and inhibitor status at the cellular level. J. Histochem. Cytochem. 42, 917-929.
    • (1994) J. Histochem. Cytochem. , vol.42 , pp. 917-929
    • Spiess, E.1    Bruning, A.2    Gack, S.3    Ulbricht, B.4    Spring, H.5    Trefz, G.6    Ebert, W.7
  • 28
    • 0028572551 scopus 로고
    • Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain
    • Mizuochi, T., Yee, S-T., Kasai, M., Kakiuchi, T., Muno, D., and Kominami, E. (1994) Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain. Immunol. Lett. 43, 189-193.
    • (1994) Immunol. Lett. , vol.43 , pp. 189-193
    • Mizuochi, T.1    Yee, S.-T.2    Kasai, M.3    Kakiuchi, T.4    Muno, D.5    Kominami, E.6
  • 30
    • 0029941098 scopus 로고    scopus 로고
    • Reconstitution of bile acid transport in the rat hepatoma McArdle RH-7777 cell line
    • Torchia, E. C., Shapiro, R. J., and Agellon, L. B. (1996) Reconstitution of bile acid transport in the rat hepatoma McArdle RH-7777 cell line. Hepatology 24, 206-211.
    • (1996) Hepatology , vol.24 , pp. 206-211
    • Torchia, E.C.1    Shapiro, R.J.2    Agellon, L.B.3
  • 31
    • 0028237920 scopus 로고
    • Maturation of human procathepsin B
    • Mach, L., Mort, J. S., and Glossl, J. (1994) Maturation of human procathepsin B. J. Biol. Chem. 269, 13,030-13,035.
    • (1994) J. Biol. Chem. , vol.269
    • Mach, L.1    Mort, J.S.2    Glossl, J.3
  • 32
    • 0027225839 scopus 로고
    • Activation of procathepsin B in human hepatoma cells: The conversion into the mature enzyme relies on the action of cathepsin B itself
    • Mach, L., Schwihla, H., Stuwe, K., Rowan, A. D., Mort, J. S., and Glossl, J. (1993) Activation of procathepsin B in human hepatoma cells: the conversion into the mature enzyme relies on the action of cathepsin B itself. Biochem. J. 293, 437-442.
    • (1993) Biochem. J. , vol.293 , pp. 437-442
    • Mach, L.1    Schwihla, H.2    Stuwe, K.3    Rowan, A.D.4    Mort, J.S.5    Glossl, J.6
  • 33
    • 0023905240 scopus 로고
    • Identification of latent procathepsi,ns B and L in microsomal lumen: Characterization of enzymatic activation and proteolytic processing in vitro
    • Nishimura, Y., Kawabata, T. and Kato, K. (1988) Identification of latent procathepsi,ns B and L in microsomal lumen: characterization of enzymatic activation and proteolytic processing in vitro. Arch. Biochem. Biophys. 261, 64-71.
    • (1988) Arch. Biochem. Biophys. , vol.261 , pp. 64-71
    • Nishimura, Y.1    Kawabata, T.2    Kato, K.3
  • 34
    • 0026664252 scopus 로고
    • Rat procathepsin B: Proteolytic procession to the mature form in vitro
    • Rowan, A. D., Mason, P., Mach, L., and Mort, J. S. (1992) Rat procathepsin B: proteolytic procession to the mature form in vitro. J. Biol. Chem. 267, 15,993o15,999.
    • (1992) J. Biol. Chem. , vol.267
    • Rowan, A.D.1    Mason, P.2    Mach, L.3    Mort, J.S.4
  • 35
    • 0025788642 scopus 로고
    • Accumulation of pepstatin in cultured eridothelial cells and its effect on endothelial processing
    • Shields, P. P., Gonzales, T. A., Charles, D., Gilligan, J. P., and Stern, W. (1991) Accumulation of pepstatin in cultured eridothelial cells and its effect on endothelial processing. Biochem. Biophy. Res. Commun. 177, 1006-1012.
    • (1991) Biochem. Biophy. Res. Commun. , vol.177 , pp. 1006-1012
    • Shields, P.P.1    Gonzales, T.A.2    Charles, D.3    Gilligan, J.P.4    Stern, W.5
  • 36
    • 3042908939 scopus 로고    scopus 로고
    • Effector proteases in bile salt-induced hepatocyte apoptosis
    • Bile Acids in Hepatobiliary Diseases - Basic Research and Clinical Application
    • Roberts, L. R., Bronk, S. F., and Gores, G. J. (1997) Effector proteases in bile salt-induced hepatocyte apoptosis, in Bile Acids in Hepatobiliary Diseases - Basic Research and Clinical Application, Falk Symposium Series 93, 265-271.
    • (1997) Falk Symposium Series , vol.93 , pp. 265-271
    • Roberts, L.R.1    Bronk, S.F.2    Gores, G.J.3
  • 37
    • 0030906632 scopus 로고    scopus 로고
    • Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C
    • Jones, B. A., Rao, Y.-P., Stravitz, R. T., and Gores, G. J. (1997) Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C. Am. J. Physiol. 272, G1109-G1115.
    • (1997) Am. J. Physiol. , vol.272
    • Jones, B.A.1    Rao, Y.-P.2    Stravitz, R.T.3    Gores, G.J.4
  • 39
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu, L. F. (1989) DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58, 351-376.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-376
    • Liu, L.F.1
  • 40
    • 0029807603 scopus 로고    scopus 로고
    • Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: Evidence for a protease-dependent pathway that does not activate cysteine protease P32
    • Adjei, P. N., Kaufmann, S. H., Leung, W. Y., Mao, F., and Gores, G. J. (1996) Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32. J. Clin. Invest. 98, 2588-2596.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2588-2596
    • Adjei, P.N.1    Kaufmann, S.H.2    Leung, W.Y.3    Mao, F.4    Gores, G.J.5
  • 41
    • 3042996305 scopus 로고    scopus 로고
    • A unique caspase 8-cathepsin B protease cascade contributes to bile salt-induced apoptosis
    • (abstract), in press
    • Faubion, W. A., Roberts, P. J., Bronk, S. F., Agellon, L. B., and Gores, G. J. A unique caspase 8-cathepsin B protease cascade contributes to bile salt-induced apoptosis. Gastroenterology (abstract), in press.
    • Gastroenterology
    • Faubion, W.A.1    Roberts, P.J.2    Bronk, S.F.3    Agellon, L.B.4    Gores, G.J.5
  • 43
    • 0030472889 scopus 로고    scopus 로고
    • Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli
    • Sarin, A., Wu, M. L., and Henkart, P. A. (1996) Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli. J. Exp. Med. 184, 2445-2450.
    • (1996) J. Exp. Med. , vol.184 , pp. 2445-2450
    • Sarin, A.1    Wu, M.L.2    Henkart, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.