-
1
-
-
0022965207
-
Prospective study of cardiomyopathy induced by adjuvant doxorubicin therapy in patients with soft-tissue sarcomas
-
Ettinghausen, S. E., Bonow, R. O., Palmeri, S. T., Seipp, C. A., Steinberg, S. M., White, D. E., and Rosenberg, S. A. (1986) Prospective study of cardiomyopathy induced by adjuvant doxorubicin therapy in patients with soft-tissue sarcomas. Arch. Surg. 121, 1445-1451
-
(1986)
Arch. Surg.
, vol.121
, pp. 1445-1451
-
-
Ettinghausen, S.E.1
Bonow, R.O.2
Palmeri, S.T.3
Seipp, C.A.4
Steinberg, S.M.5
White, D.E.6
Rosenberg, S.A.7
-
2
-
-
0022461554
-
The impact of induction anthracycline on long-term failure-free survival in childhood acute lymphoblastic leukemia
-
Hitchcock-Bryan, S., Gelber, R. D., Cassady, J. R., and Sallan S. E. (1986) The impact of induction anthracycline on long-term failure-free survival in childhood acute lymphoblastic leukemia. Med. Pediatr. Oncol. 14, 211-215
-
(1986)
Med. Pediatr. Oncol.
, vol.14
, pp. 211-215
-
-
Hitchcock-Bryan, S.1
Gelber, R.D.2
Cassady, J.R.3
Sallan, S.E.4
-
3
-
-
0030317942
-
Anthracycline-induced cardiotoxicity
-
Shan, K, Lincoff, M., and Young, J. B. (1996) Anthracycline-induced cardiotoxicity. Ann. Intern. Med. 125, 47-58
-
(1996)
Ann. Intern. Med.
, vol.125
, pp. 47-58
-
-
Shan, K.1
Lincoff, M.2
Young, J.B.3
-
4
-
-
0017656527
-
Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response
-
Myers, C. E., McGuire, W. P., Liss, R. H., Ifrim, I., Grotzinger, K., and Young, R. C. (1977) Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response. Science 197, 165-167
-
(1977)
Science
, vol.197
, pp. 165-167
-
-
Myers, C.E.1
McGuire, W.P.2
Liss, R.H.3
Ifrim, I.4
Grotzinger, K.5
Young, R.C.6
-
5
-
-
0025051505
-
Doxorubicin cardiotoxicity: Analysis of prevailing hypotheses
-
Olson, R. D., and Mushlin, P. S. (1990) Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J. 4, 3076-3086
-
(1990)
FASEB J.
, vol.4
, pp. 3076-3086
-
-
Olson, R.D.1
Mushlin, P.S.2
-
6
-
-
0016270576
-
Electrolyte and morphologic alteration of myocardium in adriamycin-treated rabbits
-
Olson, H. M., Young, D. M., Prieur, D. J., LeRoy, A. F., and Reagan, R. L. (1974) Electrolyte and morphologic alteration of myocardium in adriamycin-treated rabbits. Am. J. Pathol. 77, 439-454
-
(1974)
Am. J. Pathol.
, vol.77
, pp. 439-454
-
-
Olson, H.M.1
Young, D.M.2
Prieur, D.J.3
LeRoy, A.F.4
Reagan, R.L.5
-
7
-
-
0016835084
-
Alterations in DNA synthesis in cardiac tissue induced by adriamycin in vivo. Relationship to fatal toxicity
-
Rosenoff, S. H., Brooks, E., Bostick, F., and Young, R. E. (1975) Alterations in DNA synthesis in cardiac tissue induced by adriamycin in vivo. Relationship to fatal toxicity. Biochem. Pharmacol. 24, 1898-1901
-
(1975)
Biochem. Pharmacol.
, vol.24
, pp. 1898-1901
-
-
Rosenoff, S.H.1
Brooks, E.2
Bostick, F.3
Young, R.E.4
-
8
-
-
0000705619
-
Prevention of rat neonatal cardiomyocyte apoptosis induced by simulated in vitro ischemia and reperfusion
-
Umansky, S. R., Shapiro, J. P., Cuenco, G. M., Foehr, M. W., Bathurst, I. C., Tomei, L. D. (1997) Prevention of rat neonatal cardiomyocyte apoptosis induced by simulated in vitro ischemia and reperfusion. Cell Death Differ. 4, 608-616
-
(1997)
Cell Death Differ.
, vol.4
, pp. 608-616
-
-
Umansky, S.R.1
Shapiro, J.P.2
Cuenco, G.M.3
Foehr, M.W.4
Bathurst, I.C.5
Tomei, L.D.6
-
9
-
-
0032494175
-
Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I
-
Wang, L., Ma, W., Markovich, R., Chen, J-W., and Wang, P. H. (1998) Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I. Circ. Res. 83, 516-522
-
(1998)
Circ. Res.
, vol.83
, pp. 516-522
-
-
Wang, L.1
Ma, W.2
Markovich, R.3
Chen, J.-W.4
Wang, P.H.5
-
10
-
-
0030698045
-
Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion
-
Bielawska, A. E., Shapiro, J. P. Jiang, L., Melkonyan, H. S., Piot, C., Wolfe, C. L., Tomei, L. D., Hannun, Y. A., and Umansky, S. R. (1997) Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion. Am. J. Pathol. 151, 1257-1263
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1257-1263
-
-
Bielawska, A.E.1
Shapiro, J.P.2
Jiang, L.3
Melkonyan, H.S.4
Piot, C.5
Wolfe, C.L.6
Tomei, L.D.7
Hannun, Y.A.8
Umansky, S.R.9
-
11
-
-
0030453430
-
Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death
-
Krown, K. A., Trevor Page, M., Nguyen, C., Zechner, D., Gutierrez, V., Comstock, K. L., Glembotski, C. C., Quintana, P. J. E., and Sabbadini, R. A. (1996) Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. J. Clin. Invest. 98, 2854-2865
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2854-2865
-
-
Krown, K.A.1
Trevor Page, M.2
Nguyen, C.3
Zechner, D.4
Gutierrez, V.5
Comstock, K.L.6
Glembotski, C.C.7
Quintana, P.J.E.8
Sabbadini, R.A.9
-
12
-
-
0032031529
-
Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3
-
Vue, T. L., Wang, C., Romanic, A. M., Kikly, K., Keller, P., DeWolf, W. E. Jr., Hart, T. K., Thomas, H. C., Storer, B., Gu, J. L., Wang, X., and Feuerstein, G. Z. (1998) Staurosporine-induced apoptosis in cardiomyocytes: a potential role of caspase-3. J. Mol. Cell. Cardiol. 30, 495-507
-
(1998)
J. Mol. Cell. Cardiol.
, vol.30
, pp. 495-507
-
-
Vue, T.L.1
Wang, C.2
Romanic, A.M.3
Kikly, K.4
Keller, P.5
DeWolf W.E., Jr.6
Hart, T.K.7
Thomas, H.C.8
Storer, B.9
Gu, J.L.10
Wang, X.11
Feuerstein, G.Z.12
-
13
-
-
0021024932
-
Carnitine metabolism and functions
-
Bremer, J. (1983) Carnitine metabolism and functions. Physiol. Rev. 63, 1420-1480
-
(1983)
Physiol. Rev.
, vol.63
, pp. 1420-1480
-
-
Bremer, J.1
-
14
-
-
0027288347
-
Activation of apoptosis by serum deprivation in a teratocarcinoma cell line: Inhibition by L-acetylcarnitine
-
Galli, G., and Fratelli, M. (1993) Activation of apoptosis by serum deprivation in a teratocarcinoma cell line: inhibition by L-acetylcarnitine. Exp. Cell Res. 204, 54-60
-
(1993)
Exp. Cell Res.
, vol.204
, pp. 54-60
-
-
Galli, G.1
Fratelli, M.2
-
15
-
-
0028609205
-
L-carnitine and some of its analogs delay the onset of apoptotic cell death initiated in murine C2.8 hepatocytic cells after hepatocyte growth factor deprivation
-
Revoltella, R. P., Dal Canto, B., Caracciolo, L., and D'Urso, C. M. (1994) L-carnitine and some of its analogs delay the onset of apoptotic cell death initiated in murine C2.8 hepatocytic cells after hepatocyte growth factor deprivation. Biochim. Biophys. Acta 1224, 333-341
-
(1994)
Biochim. Biophys. Acta
, vol.1224
, pp. 333-341
-
-
Revoltella, R.P.1
Dal Canto, B.2
Caracciolo, L.3
D'Urso, C.M.4
-
16
-
-
0030948224
-
Influence of L-carnitine on CD95 cross-linking-induced apoptosis and ceramide generation in human cell lines: Correlation with its effects on purified acidic and neutral sphingomy-elinases in vitro
-
Di Marzio, L., Alesse, E., Roncaioli, P., Muzi, P., Moretti, S., Marcellini, S., Amicosante, G., De Simone, C., and Cifone, M. G. (1997) Influence of L-carnitine on CD95 cross-linking-induced apoptosis and ceramide generation in human cell lines: correlation with its effects on purified acidic and neutral sphingomy-elinases in vitro. Proc. Assoc. Am. Physicians 109, 154-163
-
(1997)
Proc. Assoc. Am. Physicians
, vol.109
, pp. 154-163
-
-
Di Marzio, L.1
Alesse, E.2
Roncaioli, P.3
Muzi, P.4
Moretti, S.5
Marcellini, S.6
Amicosante, G.7
De Simone, C.8
Cifone, M.G.9
-
17
-
-
0022624211
-
Carnitine protection against adriamycin-induced cardiomyopathy in rats
-
McFalls, E. O., Paulson, D. J., Gilbert, E. F., and Shug, A. L. (1986) Carnitine protection against adriamycin-induced cardiomyopathy in rats. Life Sci. 38, 497-505
-
(1986)
Life Sci.
, vol.38
, pp. 497-505
-
-
McFalls, E.O.1
Paulson, D.J.2
Gilbert, E.F.3
Shug, A.L.4
-
18
-
-
0030346365
-
Long-term 1-carnitine treatment prolongs the survival in rats with adriamycin-induced heart failure
-
Kawasaki, N., Lee, J. D., Shimizu, H., and Ueda, T. (1996) Long-term 1-carnitine treatment prolongs the survival in rats with adriamycin-induced heart failure. J. Cardiac Failure 2, 293-299
-
(1996)
J. Cardiac Failure
, vol.2
, pp. 293-299
-
-
Kawasaki, N.1
Lee, J.D.2
Shimizu, H.3
Ueda, T.4
-
19
-
-
0019452532
-
Antagonism of doxorubicin cardiotoxicity by carnitine is specific of the L-diastereoisomer
-
Maccari, F., and Ramacci, M. T. (1981) Antagonism of doxorubicin cardiotoxicity by carnitine is specific of the L-diastereoisomer. Biomedicine 35, 65-67
-
(1981)
Biomedicine
, vol.35
, pp. 65-67
-
-
Maccari, F.1
Ramacci, M.T.2
-
20
-
-
0022470575
-
Protective effect of L-carnitine on cardiac metabolic damage induced by doxorubicin in vitro
-
Neri, B., Cini-Neri, G., Bartalucci, S., and Bandinelli, M. (1986) Protective effect of L-carnitine on cardiac metabolic damage induced by doxorubicin in vitro. Anticancer Res. 6, 659-662
-
(1986)
Anticancer Res.
, vol.6
, pp. 659-662
-
-
Neri, B.1
Cini-Neri, G.2
Bartalucci, S.3
Bandinelli, M.4
-
21
-
-
0031080688
-
Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes
-
Abdel-aleem, S., el-Merzabani, M. M., Sayed-Ahmed, M., Taylor, D. A., and Lowe, J. E. (1997) Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes. J. Mol. Cell. Cardiol. 29, 789-797
-
(1997)
J. Mol. Cell. Cardiol.
, vol.29
, pp. 789-797
-
-
Abdel-Aleem, S.1
El-Merzabani, M.M.2
Sayed-Ahmed, M.3
Taylor, D.A.4
Lowe, J.E.5
-
22
-
-
0021333083
-
Effects of L-carnitine on adriamycin-induced cardiomyopathy in rabbit
-
Paterna, S., Furitano, G., Scaffidi, L., Barbarino, C., Campisi, D., Parisi, G., and Carreca, I. (1984) Effects of L-carnitine on adriamycin-induced cardiomyopathy in rabbit. Int. J. Tissue React. 6, 91-95
-
(1984)
Int. J. Tissue React.
, vol.6
, pp. 91-95
-
-
Paterna, S.1
Furitano, G.2
Scaffidi, L.3
Barbarino, C.4
Campisi, D.5
Parisi, G.6
Carreca, I.7
-
23
-
-
0018389404
-
Failure of carnitine to prevent adriamycin cardiomyopathy
-
Goldsmith, M. A., Suzuki, Y., Ohnuma, T., and Holland, J. F. (1979) Failure of carnitine to prevent adriamycin cardiomyopathy. Cancer Treat. Rep. 63, 558-560
-
(1979)
Cancer Treat. Rep.
, vol.63
, pp. 558-560
-
-
Goldsmith, M.A.1
Suzuki, Y.2
Ohnuma, T.3
Holland, J.F.4
-
24
-
-
0010045391
-
Effect of L-carnitine on Fas-induced apoptosis and sphingomyelinase activity in human T cell lines
-
(De Simone, C., and Famularo, G., eds) Landes Bioscience
-
Alesse, E., Di Marzio, L., Roncaioli, P., Zazzeroni, F., Angelucci, A., Ruggeri, B., Trotta, I., Muzi, P., and Cifone, G. (1997) Effect of L-carnitine on Fas-induced apoptosis and sphingomyelinase activity in human T cell lines. In Carnitine Today (De Simone, C., and Famularo, G., eds) pp. 105-117, Landes Bioscience
-
(1997)
Carnitine Today
, pp. 105-117
-
-
Alesse, E.1
Di Marzio, L.2
Roncaioli, P.3
Zazzeroni, F.4
Angelucci, A.5
Ruggeri, B.6
Trotta, I.7
Muzi, P.8
Cifone, G.9
-
25
-
-
0029148660
-
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
-
Böse, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z., and Kolesnick, R. (1995) Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82, 405-414
-
(1995)
Cell
, vol.82
, pp. 405-414
-
-
Böse, R.1
Verheij, M.2
Haimovitz-Friedman, A.3
Scotto, K.4
Fuks, Z.5
Kolesnick, R.6
-
26
-
-
0030006040
-
Daunorubicin-induced apoptosis: Triggering of ceramide generation through sphingomyelin hydrolysis
-
Jaffrézou, J. P., Levade, T., Bettaïeb, A., Andrieu, N., Bezombes, C., Maestre, N., Vermeersch, S., Rousse, A., and Laurent, G. (1996) Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis. EMBO J. 15, 2417-2424
-
(1996)
EMBO J.
, vol.15
, pp. 2417-2424
-
-
Jaffrézou, J.P.1
Levade, T.2
Bettaïeb, A.3
Andrieu, N.4
Bezombes, C.5
Maestre, N.6
Vermeersch, S.7
Rousse, A.8
Laurent, G.9
-
27
-
-
0030694255
-
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction
-
Perez, G. I., Knudson, C. M., Leykin, L., Korsmeyer, S. J., and Tilly, J. L. (1997) Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nat. Med. 3, 1228-1232
-
(1997)
Nat. Med.
, vol.3
, pp. 1228-1232
-
-
Perez, G.I.1
Knudson, C.M.2
Leykin, L.3
Korsmeyer, S.J.4
Tilly, J.L.5
-
28
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr, I., Wilhelm, D., Bohler, T., Angel, P., and Debatin, K. M. (1997) Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J. 16, 6200-6208
-
(1997)
EMBO J.
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.M.5
-
29
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
Hannun, Y. A. (1996) Functions of ceramide in coordinating cellular responses to stress. Science 274, 1855-1859
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
30
-
-
0031919157
-
Regulation of ceramide production and apoptosis
-
Kolesnick, R. N., and Kronke, M. (1998) Regulation of ceramide production and apoptosis. Annu. Rev. Physiol. 60, 643-665
-
(1998)
Annu. Rev. Physiol.
, vol.60
, pp. 643-665
-
-
Kolesnick, R.N.1
Kronke, M.2
-
31
-
-
0025934998
-
Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein
-
Jaffrézou, J. P., Herbert, J. M., Levade, T., Gau, M. N., Chatelain, P., Laurent, G. (1991) Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein. J. Biol. Chem. 266, 19858-19864
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19858-19864
-
-
Jaffrézou, J.P.1
Herbert, J.M.2
Levade, T.3
Gau, M.N.4
Chatelain, P.5
Laurent, G.6
-
33
-
-
0027512102
-
A safe and rapid method for analyzing apoptosis-induced fragmentation of DNA extracted from tissues or cultured cells
-
Prigent, P., Blanpied, C., Aten, J., and Hirsch, F. (1993) A safe and rapid method for analyzing apoptosis-induced fragmentation of DNA extracted from tissues or cultured cells. J. Immunol. Methods 160, 139-140
-
(1993)
J. Immunol. Methods
, vol.160
, pp. 139-140
-
-
Prigent, P.1
Blanpied, C.2
Aten, J.3
Hirsch, F.4
-
34
-
-
0028323164
-
A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry
-
Gong, J., Traganos, F., and Darzynkiewicz, Z. (1994) A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal. Biochem. 218, 314-319
-
(1994)
Anal. Biochem.
, vol.218
, pp. 314-319
-
-
Gong, J.1
Traganos, F.2
Darzynkiewicz, Z.3
-
35
-
-
0017610392
-
Simple and rapid fluorometric method for DNA microassay
-
Kapuscinski, J., and Skooczylas, B. (1977) Simple and rapid fluorometric method for DNA microassay. Anal. Biochem. 83, 252-257
-
(1977)
Anal. Biochem.
, vol.83
, pp. 252-257
-
-
Kapuscinski, J.1
Skooczylas, B.2
-
36
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
37
-
-
70449158340
-
A simple method for the isolation and purification of total lipids from animal tissues
-
Folch, J., Lees, M., and Sloane Stanley, G. H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226, 497-509
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
38
-
-
0028810984
-
Low temperatures and hypertonicity do not block cytokine-induced stimulation of the sphingomyelin pathway but inhibit nuclear factor-kappa B activation
-
Andrieu, N., Salvayre, R., Jaffrézou, J. P., and Levade, T. (1995) Low temperatures and hypertonicity do not block cytokine-induced stimulation of the sphingomyelin pathway but inhibit nuclear factor-kappa B activation. J. Biol. Chem. 270, 24518-24524
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24518-24524
-
-
Andrieu, N.1
Salvayre, R.2
Jaffrézou, J.P.3
Levade, T.4
-
39
-
-
0343879238
-
Assay of inorganic phosphate, total phosphate and phosphatases
-
Ames, B. N. (1966) Assay of inorganic phosphate, total phosphate and phosphatases. Methods Enzymol. 8, 115-118
-
(1966)
Methods Enzymol.
, vol.8
, pp. 115-118
-
-
Ames, B.N.1
-
40
-
-
0029556391
-
Ceramide quantitation: Evaluation of a mixed micellar assay using E. coli diacylglycerol kinase
-
van Veldhoven, P. P., Bishop, W. R., Yurivich, D. A., and Bell, R. M. (1995) Ceramide quantitation: evaluation of a mixed micellar assay using E. coli diacylglycerol kinase. Biochem. Mol. Biol. Int. 36, 21-30
-
(1995)
Biochem. Mol. Biol. Int.
, vol.36
, pp. 21-30
-
-
Van Veldhoven, P.P.1
Bishop, W.R.2
Yurivich, D.A.3
Bell, R.M.4
-
41
-
-
0015951217
-
Determination of long-chain base in glycosphingolipids with fluorescamine
-
Kisic, A., and Rapport, M. M. (1974) Determination of long-chain base in glycosphingolipids with fluorescamine. J. Lipid Res. 15, 179-180
-
(1974)
J. Lipid Res.
, vol.15
, pp. 179-180
-
-
Kisic, A.1
Rapport, M.M.2
-
42
-
-
0033587181
-
Retroviral-mediated correction of the metabolic defect in cultured Farber disease cells
-
In press
-
Medin, J. A., Takenaka, T., Carpentier, S., Garcia, S., Basile, J. P., Ségui, B., Andrieu-Abadie, N., Auge, N., Salvayre, R., and Levade, T. (1999) Retroviral-mediated correction of the metabolic defect in cultured Farber disease cells. Hum. Gene Ther. In press
-
(1999)
Hum. Gene Ther.
-
-
Medin, J.A.1
Takenaka, T.2
Carpentier, S.3
Garcia, S.4
Basile, J.P.5
Ségui, B.6
Andrieu-Abadie, N.7
Auge, N.8
Salvayre, R.9
Levade, T.10
-
43
-
-
0028108015
-
Functional dichotomy of neutral and acid sphingomyelinases in tumor necrosis factor signaling
-
Wiegmann, K., Schütze, S., Machleidt, T., Witte, D., and Krönke, M. (1994) Functional dichotomy of neutral and acid sphingomyelinases in tumor necrosis factor signaling. Cell 78, 1005-1015
-
(1994)
Cell
, vol.78
, pp. 1005-1015
-
-
Wiegmann, K.1
Schütze, S.2
Machleidt, T.3
Witte, D.4
Krönke, M.5
-
44
-
-
0023514977
-
Cellular and plasma adriamycin concentrations in long-term infusion therapy of leukemia patients
-
Speth, P.A. S., Linssen, P. C. M., Boezeman, J. B. M., Wessels, H. M. C., and Haanen, C. (1987) Cellular and plasma adriamycin concentrations in long-term infusion therapy of leukemia patients. Cancer Chemother. Pharmacol. 20, 311-315
-
(1987)
Cancer Chemother. Pharmacol.
, vol.20
, pp. 311-315
-
-
Speth, P.A.S.1
Linssen, P.C.M.2
Boezeman, J.B.M.3
Wessels, H.M.C.4
Haanen, C.5
-
45
-
-
0030612721
-
Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells
-
Boland, M. P., Foster, S. J., and O'Neill, L. A. (1997) Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells. J. Biol. Chem. 272, 12952-12960
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12952-12960
-
-
Boland, M.P.1
Foster, S.J.2
O'Neill, L.A.3
-
46
-
-
0029729842
-
Apoptosis in the heart: When and why?
-
Bromme, H. J., and Holtz, J. (1996) Apoptosis in the heart: when and why? Mol. Cell. Biochem. 163, 261-275
-
(1996)
Mol. Cell. Biochem.
, vol.163
, pp. 261-275
-
-
Bromme, H.J.1
Holtz, J.2
-
47
-
-
0032526374
-
Apoptosis: Basic mechanisms and implications for cardiovascular disease
-
Haunstetter, A., and Izumo, S. (1998) Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ. Res. 82, 1111-1129
-
(1998)
Circ. Res.
, vol.82
, pp. 1111-1129
-
-
Haunstetter, A.1
Izumo, S.2
-
48
-
-
0030829808
-
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy
-
Li, Q., Li, B., Wang, X., Leri, A., Jana, K. P., Liu, Y., Kajstura, J., Baserga, R., and Anversa, P. (1997) Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J. Clin. Invest. 100, 1991-1999
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1991-1999
-
-
Li, Q.1
Li, B.2
Wang, X.3
Leri, A.4
Jana, K.P.5
Liu, Y.6
Kajstura, J.7
Baserga, R.8
Anversa, P.9
-
49
-
-
0032498614
-
Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol
-
Yue, T. L., Ma, X. L., Wang, X., Romanic, A. M., Liu, G. L., Louden, C., Gu, J. L., Kumar, S., Poste, G., Ruffolo, R. R. Jr, and Feuerstein, G. Z. (1998) Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol. Circ. Res. 82, 166-174
-
(1998)
Circ. Res.
, vol.82
, pp. 166-174
-
-
Yue, T.L.1
Ma, X.L.2
Wang, X.3
Romanic, A.M.4
Liu, G.L.5
Louden, C.6
Gu, J.L.7
Kumar, S.8
Poste, G.9
Ruffolo R.R., Jr.10
Feuerstein, G.Z.11
-
50
-
-
0032054183
-
The dose-dependent effects of L-carnitine in myocardial protection in normothermic ischemia
-
Tatlican, O., Kalaycioglu, S., Gokgoz, L., Oktar, L., Oz, E., Soncul, H., Sinci, V., Turkozkan, N., Yener, A., and Ersoz, A. (1998) The dose-dependent effects of L-carnitine in myocardial protection in normothermic ischemia. Cardiovasc. Surg. 6, 145-148
-
(1998)
Cardiovasc. Surg.
, vol.6
, pp. 145-148
-
-
Tatlican, O.1
Kalaycioglu, S.2
Gokgoz, L.3
Oktar, L.4
Oz, E.5
Soncul, H.6
Sinci, V.7
Turkozkan, N.8
Yener, A.9
Ersoz, A.10
-
51
-
-
0027511687
-
Programmed cell death induced by ceramide
-
Obeid, L. M., Linardic, C. M., Karolak, L. A., and Hannun, Y. A. (1993) Programmed cell death induced by ceramide. Science 259, 1769-1771
-
(1993)
Science
, vol.259
, pp. 1769-1771
-
-
Obeid, L.M.1
Linardic, C.M.2
Karolak, L.A.3
Hannun, Y.A.4
-
52
-
-
0028095477
-
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acid sphingomyelinase
-
Cifone, M. G., De Maria, R., Roncaioli, P., Rippo, M. R., Azuma, M., Lanier, L. L., Santoni, A., and Testi, R. (1994) Apoptotic signaling through CD95 (Fas/Apo-1) activates an acid sphingomyelinase. J. Exp. Med. 180, 1547-1552
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1547-1552
-
-
Cifone, M.G.1
De Maria, R.2
Roncaioli, P.3
Rippo, M.R.4
Azuma, M.5
Lanier, L.L.6
Santoni, A.7
Testi, R.8
-
53
-
-
0345218674
-
Doxorubicin induces ceramide accumulation and apoptosis af adult rat cardiac myocytes in vitro
-
Delpy, E., Hatem, S. N., Andrieu-Abadie, N., Rucker-Martin, G., Jaffrézou, J-P., Laurent, G., Levade, T., and Mercadier, J-J. (1998) Doxorubicin induces ceramide accumulation and apoptosis af adult rat cardiac myocytes in vitro. Circulation (Suppl. 1), 98, 3893
-
(1998)
Circulation
, vol.98
, Issue.SUPPL. 1
, pp. 3893
-
-
Delpy, E.1
Hatem, S.N.2
Andrieu-Abadie, N.3
Rucker-Martin, G.4
Jaffrézou, J.-P.5
Laurent, G.6
Levade, T.7
Mercadier, J.-J.8
-
54
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
Santana, P., Pena, L. A., Haimovitz-Friedman, A., Martin, S., Green, D., McLoughlin, M., Cordon-Cardo, C., Schuchman, E. H., Fuks, Z., and Kolesnick, R. (1996) Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell 86, 189-199
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
55
-
-
0032502854
-
Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue
-
Chatelut, M., Leruth, M., Harzer, K., Dagan, A., Marchesini, S., Gatt, S., Salvayre, R., Courtoy, P., and Levade, T. (1998) Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue. FEBS Lett. 426, 102-106
-
(1998)
FEBS Lett.
, vol.426
, pp. 102-106
-
-
Chatelut, M.1
Leruth, M.2
Harzer, K.3
Dagan, A.4
Marchesini, S.5
Gatt, S.6
Salvayre, R.7
Courtoy, P.8
Levade, T.9
-
56
-
-
0032079524
-
Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death
-
Liu, B., Andrieu-Abadie, N., Levade, T., Zhang, P., Obeid, L. M., and Hannun, Y. A. (1998) Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death. J. Biol. Chem. 273, 11313-11320
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11313-11320
-
-
Liu, B.1
Andrieu-Abadie, N.2
Levade, T.3
Zhang, P.4
Obeid, L.M.5
Hannun, Y.A.6
-
57
-
-
0017811778
-
Changes in tissue levels of carnitine and other metabolites during myocardial ischemia and anoxia
-
Shug, A. L., Thomsen, J. H., Folts, J. D., Bittar, N., Klein, M. I., Koke, J. R., and Huth, P. J. (1978) Changes in tissue levels of carnitine and other metabolites during myocardial ischemia and anoxia. Arch. Biochem. Biophys. 187, 25-33
-
(1978)
Arch. Biochem. Biophys.
, vol.187
, pp. 25-33
-
-
Shug, A.L.1
Thomsen, J.H.2
Folts, J.D.3
Bittar, N.4
Klein, M.I.5
Koke, J.R.6
Huth, P.J.7
-
58
-
-
0032054183
-
The dose-dependent effects of L-carnitine in myocardial protection in normothermic ischemia
-
Tatlican, O., Kalaycioglu, S., Gokgoz, L., Oktar, L., Oz, E., Soncul, H., Sinci, V., Turkozkan, N., Yener, A., Ersoz, A. (1998) The dose-dependent effects of L-carnitine in myocardial protection in normothermic ischemia. Cardiavasc. Surg. 6, 145-148
-
(1998)
Cardiavasc. Surg.
, vol.6
, pp. 145-148
-
-
Tatlican, O.1
Kalaycioglu, S.2
Gokgoz, L.3
Oktar, L.4
Oz, E.5
Soncul, H.6
Sinci, V.7
Turkozkan, N.8
Yener, A.9
Ersoz, A.10
-
59
-
-
0031018842
-
Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HPV syndrome
-
Cossarizza, A., Mussini, C., Mongiardo, N., Borghi, V., Sabbatini, A., De Rienzo, B., and Franceschi, C. (1997) Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HPV syndrome. AIDS 11, 19-26
-
(1997)
AIDS
, vol.11
, pp. 19-26
-
-
Cossarizza, A.1
Mussini, C.2
Mongiardo, N.3
Borghi, V.4
Sabbatini, A.5
De Rienzo, B.6
Franceschi, C.7
-
60
-
-
0023179879
-
Changes in levels of lipid peroxides and activities of superoxide dismutase and catalase in isoproterenol induced myocardial infarction in rats
-
Kumari, S. S., and Menon, V. P. (1987) Changes in levels of lipid peroxides and activities of superoxide dismutase and catalase in isoproterenol induced myocardial infarction in rats. Indian J. Exp. Biol. 25, 419-23
-
(1987)
Indian J. Exp. Biol.
, vol.25
, pp. 419-423
-
-
Kumari, S.S.1
Menon, V.P.2
-
61
-
-
0030855953
-
Adriamycin cardiomyopathy: Pathophysiology and prevention
-
Singal, P. K., Iliskovic, N., Li, T., and Kumar, D. (1997) Adriamycin cardiomyopathy: pathophysiology and prevention. FASEB J. 11, 931-936
-
(1997)
FASEB J.
, vol.11
, pp. 931-936
-
-
Singal, P.K.1
Iliskovic, N.2
Li, T.3
Kumar, D.4
-
62
-
-
0019817511
-
Mechanism of adriamycin cardiotoxicity: Evidence for oxidative stress
-
Olson, R. D., Boerth, R. C., Gerber, J. G., and Nies, A. S. (1981) Mechanism of adriamycin cardiotoxicity: evidence for oxidative stress. Life Sci. 29, 1393-1401
-
(1981)
Life Sci.
, vol.29
, pp. 1393-1401
-
-
Olson, R.D.1
Boerth, R.C.2
Gerber, J.G.3
Nies, A.S.4
-
63
-
-
0023726412
-
Adriamycin-induced free radical formation in the perfused rat heart: Implications for cardiotoxicity
-
Rajagopalan, S., Politi, P. M., Sinha, B. K., and Myers, C. E. (1988) Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity. Cancer Res. 48, 4766-4769
-
(1988)
Cancer Res.
, vol.48
, pp. 4766-4769
-
-
Rajagopalan, S.1
Politi, P.M.2
Sinha, B.K.3
Myers, C.E.4
-
64
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
-
Garcia-Ruiz, C., Colell, A., Mari, M., Morales, A., and Fernandez-Checa, J. C. (1997) Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J. Biol. Chem. 272, 11369-11377
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11369-11377
-
-
Garcia-Ruiz, C.1
Colell, A.2
Mari, M.3
Morales, A.4
Fernandez-Checa, J.C.5
-
65
-
-
1842375100
-
Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis
-
Quillet-Mary, A., Jaffrézou, J-P., Mansat, V., Bordier, C., Naval, J., and Laurent, G. (1997) Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J. Biol. Chem. 272, 21388-21395
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21388-21395
-
-
Quillet-Mary, A.1
Jaffrézou, J.-P.2
Mansat, V.3
Bordier, C.4
Naval, J.5
Laurent, G.6
-
66
-
-
0031013369
-
Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis
-
Paumen, M. B., Ishida, Y., Muramatsu, M., Yamamoto, M., and Honjo, T. (1997) Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J. Biol. Chem. 272, 3324-3329
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3324-3329
-
-
Paumen, M.B.1
Ishida, Y.2
Muramatsu, M.3
Yamamoto, M.4
Honjo, T.5
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