-
1
-
-
0036597371
-
CD4+ CD25+ suppressor T cells: More questions than answers
-
SHEVACH EM: CD4+ CD25+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. (2002) 2(6):389-400.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, Issue.6
, pp. 389-400
-
-
Shevach, E.M.1
-
2
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
SAKAGUCHI S, SAKAGUCHI N, ASANO M, ITOH M, TODA M: Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. (1995) 155(3):1151-1164. This work is the first demonstration of the endogenous status and role of CD4+CD25+ T cells.
-
(1995)
J. Immunol.
, vol.155
, Issue.3
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
3
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic self-tolerance
-
SAKAGUCHI S: Regulatory T cells: key controllers of immunologic self-tolerance. Cell (2000) 101(5):455-458.
-
(2000)
Cell
, vol.101
, Issue.5
, pp. 455-458
-
-
Sakaguchi, S.1
-
4
-
-
0036467522
-
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
KINGSLEY CI, KARIM M, BUSHELL AR, WOOD KJ: CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. (2002) 168(3):1080-1086.
-
(2002)
J. Immunol.
, vol.168
, Issue.3
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
5
-
-
0035979182
-
Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection
-
IWASHIRO M, MESSER RJ, PETERSON KE et al.: Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection. Proc. Natl. Acad. Sci. USA (2001) 98(16):9226-9230.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.16
, pp. 9226-9230
-
-
Iwashiro, M.1
Messer, R.J.2
Peterson, K.E.3
-
6
-
-
0036107373
-
CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice
-
HORI S, CARVALHO TL, DEMENGEOT J: CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur. J. Immunol. (2002) 32(5):1282-1291.
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.5
, pp. 1282-1291
-
-
Hori, S.1
Carvalho, T.L.2
Demengeot, J.3
-
7
-
-
0033136302
-
Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
ITOH M, TAKAHASHI T, SAKAGUCHI N et al. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. (1999) 162(9):5317-5326.
-
(1999)
J. Immunol.
, vol.162
, Issue.9
, pp. 5317-5326
-
-
Itoh, M.1
Takahashi, T.2
Sakaguchi, N.3
-
8
-
-
0035180065
-
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
-
SAKAGUCHI S, SAKAGUCHI N, SHIMIZU J et al.: Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Arv. (2001) 182:18-32.
-
(2001)
Immunol. Arv.
, vol.182
, pp. 18-32
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Shimizu, J.3
-
9
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
comment
-
MCHUGH RS, WHITTERS MJ, PICCIRILLO CA et al.: CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. [comment]. Immunity. (2002) 16(2):311-323.
-
(2002)
Immunity
, vol.16
, Issue.2
, pp. 311-323
-
-
Mchugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
-
10
-
-
0036170938
-
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
-
comment
-
SHIMIZU J,YAMAZAKI S, TAKAHASHI T, ISHIDA Y, SAKAGUCHI S: Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. [comment]. Nat. Immun. (2002) 3(2):135-142.
-
(2002)
Nat. Immun.
, vol.3
, Issue.2
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
11
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
comment
-
HORI S, NOMURA T, SAKAGUCHI S: Control of regulatory T cell development by the transcription factor Foxp3. [comment]. Science (2003) 299(5609):1057-1061. References [11-13] were the first to show that Foxp3 is a specific marker for CD4+CD25+ regulatory T cells.
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
12
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
comment
-
FONTENOT JD, GAVIN MA, RUDENSKY AY: Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. [comment]. Nat. Immun. (2003) 4 (4):330-336. See [11]
-
(2003)
Nat. Immun.
, vol.4
, Issue.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
13
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
comment
-
KHATTRI R, COX T, YASAYKO SA, RAMSDELL F: An essential role for Scurfin in CD4+CD25+ T regulatory cells. [comment]. Nat. Immun. (2003) 4(4):337-342. See [11].
-
(2003)
Nat. Immun.
, vol.4
, Issue.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
14
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polydonal T cell activation in vitro by inhibiting interleukin 2 production
-
THORNTON AM, SHEVACH EM: CD4+CD25+ immunoregulatory T cells suppress polydonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. (1998) 188(2):287-296. A role for CTLA-4 and surface-expressed TGF-β in such inhibition has been suggested, but remains controversial.
-
(1998)
J. Exp. Med.
, vol.188
, Issue.2
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
15
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
NAKAMURA K, KITANI A, STROBER W: Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. (2001) 194(5):629-644.
-
(2001)
J. Exp. Med.
, vol.194
, Issue.5
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
16
-
-
0037099613
-
CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor {beta} 1 production and responsiveness
-
PICCIRILLO CA, LETTERIO JJ, THORNTON AM et al.: CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor {beta} 1 production and responsiveness. J Exp. Med (2002) 196(2):237-246.
-
(2002)
J Exp. Med.
, vol.196
, Issue.2
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
-
17
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
TAKAHASHI T, TAGAMI T, YAMAZAKI S et al.: Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med (2000) 192(2):303-310.
-
(2000)
J. Exp. Med.
, vol.192
, Issue.2
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
-
18
-
-
0035421654
-
Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
-
PICCIRILLO CA, SHEVACH EM: Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J. Immunol. (2001) 167(3):1137-1140.
-
(2001)
J. Immunol.
, vol.167
, Issue.3
, pp. 1137-1140
-
-
Piccirillo, C.A.1
Shevach, E.M.2
-
19
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
TAKAHASHI T, KUNIYASU Y, TODA M et al.: Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. (1998) 10(12):1969-1980.
-
(1998)
Int. Immunol.
, vol.10
, Issue.12
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
-
20
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
comment
-
PASARE C, MEDZHITOV R: Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. [comment]. Science (2003) 299(5609):1033-1036. This work demonstrates that regulatory T cells can themselves be controlled by the level of activation of dendritic cells.
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
21
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
READ S, MALMSTROM V, POWRIE F: Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. (2000) 192(2):295-302.
-
(2000)
J. Exp. Med.
, vol.192
, Issue.2
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
22
-
-
0037243827
-
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
-
MALOY KJ, SALAUN L, CAHILL R, DOUGAN G, SAUNDERS NJ, POWRIE F: CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. (2003) 197:111-119.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
Salaun, L.2
Cahill, R.3
Dougan, G.4
Saunders, N.J.5
Powrie, F.6
-
23
-
-
0037148511
-
Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper Type 1 responses by Bordetella pertussis
-
MCGUIRK P, MCCANN C, MILLS KH: Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper Type 1 responses by Bordetella pertussis. J. Exp. Med. (2002) 195(2):221-231.
-
(2002)
J. Exp. Med.
, vol.195
, Issue.2
, pp. 221-231
-
-
Mcguirk, P.1
Mccann, C.2
Mills, K.H.3
-
24
-
-
0037099719
-
Infectious tolerance: Human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells
-
JONULEIT H, SCHMITT E, KAKIRMAN H et al.: Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J. Exp. Med (2002) 196(2):255-260.
-
(2002)
J. Exp. Med.
, vol.196
, Issue.2
, pp. 255-260
-
-
Jonuleit, H.1
Schmitt, E.2
Kakirman, H.3
-
25
-
-
0037099733
-
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
-
erratum appears in J. Exp. Med. (2002) 196(4):559
-
DIECKMANN D, BRUETT CH, PLOETTNER H, LUTZ MB, SCHULER G: Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. [erratum appears in J. Exp. Med. (2002) 196(4):559]. J. Exp. Med. (2002) 196(2):247-253.
-
(2002)
J. Exp. Med.
, vol.196
, Issue.2
, pp. 247-253
-
-
Dieckmann, D.1
Bruett, C.H.2
Ploettner, H.3
Lutz, M.B.4
Schuler, G.5
-
26
-
-
0035048929
-
Leishmania-sand fly interactions controlling species-specific vector competence
-
SACKS DL: Leishmania-sand fly interactions controlling species-specific vector competence. Cell Microbiol. (2001) 3(4):189-196.
-
(2001)
Cell Microbiol.
, vol.3
, Issue.4
, pp. 189-196
-
-
Sacks, D.L.1
-
27
-
-
0034686436
-
Fibroblasts as host cells in latent leishmaniosis
-
BOGDAN C, DONHAUSER N, DORING R et al.: Fibroblasts as host cells in latent leishmaniosis. J. Exp. Med. (2000) 191(12):2121-2130. The first analysis of host cells in a latendy infected site.
-
(2000)
J. Exp. Med.
, vol.191
, Issue.12
, pp. 2121-2130
-
-
Bogdan, C.1
Donhauser, N.2
Doring, R.3
-
28
-
-
0029112365
-
Dendritic cells seclude Leishmania parasites that persist in cured mice- -a role in the maintenance of T-cell memory?
-
MOLL H, FLOHE S, BLANK C: Dendritic cells seclude Leishmania parasites that persist in cured mice- -a role in the maintenance of T-cell memory? Adv. Exp. Med. Biol. (1995) 378:507-509.
-
(1995)
Adv. Exp. Med. Biol.
, vol.378
, pp. 507-509
-
-
Moll, H.1
Flohe, S.2
Blank, C.3
-
29
-
-
0032972363
-
T-cell response in human leishmaniasis
-
KHARAZMI A, KEMP K, ISMAIL A et al.: T-cell response in human leishmaniasis. Immunol. Lett. (1999) 65(1-2):105-108.
-
(1999)
Immunol. Lett.
, vol.65
, Issue.1-2
, pp. 105-108
-
-
Kharazmi, A.1
Kemp, K.2
Ismail, A.3
-
30
-
-
0033178579
-
The human immune response during cutaneous leishmaniasis: NO problem
-
MOSSALAYI MD, AROCK M, MAZIER D, VINCENDEAU P, VOULDOUKIS I: The human immune response during cutaneous leishmaniasis: NO problem. Parasitology Today (1999) 15(8):342-345.
-
(1999)
Parasitology Today
, vol.15
, Issue.8
, pp. 342-345
-
-
Mossalayi, M.D.1
Arock, M.2
Mazier, D.3
Vincendeau, P.4
Vouldoukis, I.5
-
31
-
-
0036831673
-
The immunology of susceptibility and resistance to Leishmania major in mice
-
SACKS D, NOBEN-TRAUTH N: The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. (2002) 2 (11):845-858.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, Issue.11
, pp. 845-858
-
-
Sacks, D.1
Noben-Trauth, N.2
-
33
-
-
0032713467
-
Relapse of cutaneous leishmaniasis in a patient with an infected subcutaneous rheumatoid nodule
-
VARDY DA, COHEN A, KACHKO L, ZVULUNOV A, FRANKENBURG S: Relapse of cutaneous leishmaniasis in a patient with an infected subcutaneous rheumatoid nodule. Br. J. Dermatol. (1999) 141(5):914-917.
-
(1999)
Br. J. Dermatol.
, vol.141
, Issue.5
, pp. 914-917
-
-
Vardy, D.A.1
Cohen, A.2
Kachko, L.3
Zvulunov, A.4
Frankenburg, S.5
-
34
-
-
0035754195
-
Leishmaniasis as an emerging infection
-
CHOI CM, LERNER EA: Leishmaniasis as an emerging infection. J. Invest. Dermatol. (2001) 6(3):175-182.
-
(2001)
J. Invest. Dermatol.
, vol.6
, Issue.3
, pp. 175-182
-
-
Choi, C.M.1
Lerner, E.A.2
-
35
-
-
0030249179
-
Mononudear phagocytes and dendritic leukocytes in the skin
-
MILON G, BELKAID Y, MOUFQIA J et al.: Mononudear phagocytes and dendritic leukocytes in the skin. Clin. Dermatol. (1996) 14(5):465-470.
-
(1996)
Clin. Dermatol.
, vol.14
, Issue.5
, pp. 465-470
-
-
Milon, G.1
Belkaid, Y.2
Moufqia, J.3
-
36
-
-
0028933795
-
The regulation of immunity to Leishmania major
-
REINER SL, LOCKSLEY RM: The regulation of immunity to Leishmania major. Ann. Rev Immunol (1995) 13:151-177. References [36-47] established the mechanism of resistance to Leishmania infection.
-
(1995)
Ann. Rev Immunol.
, vol.13
, pp. 151-177
-
-
Reiner, S.L.1
Locksley, R.M.2
-
37
-
-
0031963998
-
Experimental cutaneous leishmaniasis: Induction and regulation of T cells following infection of mice with Leishmania major
-
SCOTT P, FARRELL JP: Experimental cutaneous leishmaniasis: induction and regulation of T cells following infection of mice with Leishmania major. Chem. Immunol. (1998) 70:60-80. See [36].
-
(1998)
Chem. Immunol.
, vol.70
, pp. 60-80
-
-
Scott, P.1
Farrell, J.P.2
-
38
-
-
0020034005
-
Immunologic regulation of experimental cutaneous leishmaniasis. V. Characterization of effector and specific suppressor T cells
-
LIEW FY, HALE C, HOWARD JG: Immunologic regulation of experimental cutaneous leishmaniasis. V. Characterization of effector and specific suppressor T cells. J. Immunol. (1982) 128(4):1917-1922. See [36].
-
(1982)
J. Immunol.
, vol.128
, Issue.4
, pp. 1917-1922
-
-
Liew, F.Y.1
Hale, C.2
Howard, J.G.3
-
39
-
-
0023200625
-
Involvement ofspecific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis
-
TITUS RG, MILON G, MARCHAL G et al.: Involvement ofspecific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis. Eur. J. Immunol. (1987) 17(10):1429-1433. See [36].
-
(1987)
Eur. J. Immunol.
, vol.17
, Issue.10
, pp. 1429-1433
-
-
Titus, R.G.1
Milon, G.2
Marchal, G.3
-
40
-
-
0024412797
-
Administration of monoclonal anti-IFN-gamma antibodies in viabrogates natural resistance of C3H/HeN mice to infection with Leishmania major
-
BELOSEVIC M, FINBLOOM DS, VAN DER MEIDE PH, SLAYTER MV, NACY CA: Administration of monoclonal anti-IFN-gamma antibodies in viabrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. (1989) 143(1):266-274. See [36].
-
(1989)
J. Immunol.
, vol.143
, Issue.1
, pp. 266-274
-
-
Belosevic, M.1
Finbloom, D.S.2
Van Der Meide, P.H.3
Slayter, M.V.4
Nacy, C.A.5
-
41
-
-
0027158442
-
IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts
-
HEINZEL FP, RERKO RM, HATAM F, LOCKSLEY RM: IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts. J. Immunol. (1993) 150(9):3924-3931. See [36].
-
(1993)
J. Immunol.
, vol.150
, Issue.9
, pp. 3924-3931
-
-
Heinzel, F.P.1
Rerko, R.M.2
Hatam, F.3
Locksley, R.M.4
-
42
-
-
0027309318
-
Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective T helper Type 1 immune response
-
SYPEK JP, CHUNG CL, MAYOR SE et al.: Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper Type 1 immune response. J. Exp. Med. (1993) 177(6):1797-1802. See [36].
-
(1993)
J. Exp. Med.
, vol.177
, Issue.6
, pp. 1797-1802
-
-
Sypek, J.P.1
Chung, C.L.2
Mayor, S.E.3
-
43
-
-
0028129526
-
Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
-
STENGER S, THURING H, ROLLINGHOFF M, BOGDAN C: Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. (1994) 180(3):783-793. See [36].
-
(1994)
J. Exp. Med.
, vol.180
, Issue.3
, pp. 783-793
-
-
Stenger, S.1
Thuring, H.2
Rollinghoff, M.3
Bogdan, C.4
-
44
-
-
0028948205
-
Class II major histocompatibility complex-defident mice initially control an infection with Leishmania major but succumb to the disease
-
CHAKKALATH HR, THEODOS CM, MARKOWITZ JS et al.: Class II major histocompatibility complex-defident mice initially control an infection with Leishmania major but succumb to the disease. J. Infect. Dis. (1995) 171(5):1302-1308. See [36].
-
(1995)
J. Infect. Dis.
, vol.171
, Issue.5
, pp. 1302-1308
-
-
Chakkalath, H.R.1
Theodos, C.M.2
Markowitz, J.S.3
-
45
-
-
0029793160
-
Leishmania major infection in major histocompatibility complex class II-deficient mice: CD8+ T cells do not mediate a protective immune response
-
ERB K, BLANK C, RITTER U, BLUETHMANN H, MOLL H: Leishmania major infection in major histocompatibility complex class II-deficient mice: CD8+ T cells do not mediate a protective immune response. Immunobiology (1996) 195(2):243-260. See [36].
-
(1996)
Immunobiology
, vol.195
, Issue.2
, pp. 243-260
-
-
Erb, K.1
Blank, C.2
Ritter, U.3
Bluethmann, H.4
Moll, H.5
-
46
-
-
0029933509
-
Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity
-
KAMANAKA M, YU P, YASUI T et al.: Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity. Immunity (1996) 4(3):275-281. See [36] and [48].
-
(1996)
Immunity
, vol.4
, Issue.3
, pp. 275-281
-
-
Kamanaka, M.1
Yu, P.2
Yasui, T.3
-
47
-
-
0029965957
-
CD40 ligand is required for protective cell-mediated immunity to Leishmania major
-
CAMPBELL KA, OVENDALE PJ, KENNEDY MK et al.: CD40 ligand is required for protective cell-mediated immunity to Leishmania major. Immunity (1996) 4(3):283-289. See [36] and [48].
-
(1996)
Immunity
, vol.4
, Issue.3
, pp. 283-289
-
-
Campbell, K.A.1
Ovendale, P.J.2
Kennedy, M.K.3
-
48
-
-
0037406839
-
The levels and patterns of cytokines produced by CD4 T lymphocytes of BALB/c mice infected with Leishmania major by inoculation into the ear dermis depend on the infectiousness and size of the inoculum
-
LANG T, COURRET N, COLLE JH, MILON G, ANTOINE JC: The levels and patterns of cytokines produced by CD4 T lymphocytes of BALB/c mice infected with Leishmania major by inoculation into the ear dermis depend on the infectiousness and size of the inoculum. Infect. Immun. (2003) 71(5):2674-2683. References [46-48] showed that early IL-4 production by LACK-reactive cells controls susceptibility to L. major.
-
(2003)
Infect. Immun.
, vol.71
, Issue.5
, pp. 2674-2683
-
-
Lang, T.1
Courret, N.2
Colle, J.H.3
Milon, G.4
Antoine, J.C.5
-
49
-
-
0031739807
-
Parasite dose determines the Th1/Th2 nature of the response to Leishmania major independently of infection route and strain of host or parasite
-
MENON JN, BRETSCHER PA: Parasite dose determines the Th1/Th2 nature of the response to Leishmania major independently of infection route and strain of host or parasite. Eur. J. Immunol. (1998) 28(12):4020-4028.
-
(1998)
Eur. J. Immunol.
, vol.28
, Issue.12
, pp. 4020-4028
-
-
Menon, J.N.1
Bretscher, P.A.2
-
50
-
-
0029849205
-
Resistance to Leishmania major induced by tolerance to a single antigen
-
JULIA V, RASSOULZADEGAN M, GLAICHENHAUS N: Resistance to Leishmania major induced by tolerance to a single antigen. Science (1996) 274(5286):421-423.
-
(1996)
Science
, vol.274
, Issue.5286
, pp. 421-423
-
-
Julia, V.1
Rassoulzadegan, M.2
Glaichenhaus, N.3
-
51
-
-
0001123104
-
IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice
-
LAUNOIS P, MAILLARD I, PINGEL S et al.: IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity (1997) 6(5):541-549.
-
(1997)
Immunity
, vol.6
, Issue.5
, pp. 541-549
-
-
Launois, P.1
Maillard, I.2
Pingel, S.3
-
52
-
-
0034193027
-
In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease
-
HIMMELRICH H, LAUNOIS P, MAILLARD I et al.: In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J. Immunol. (2000) 164(9):4819-4825.
-
(2000)
J. Immunol.
, vol.164
, Issue.9
, pp. 4819-4825
-
-
Himmelrich, H.1
Launois, P.2
Maillard, I.3
-
53
-
-
0033045577
-
CD4(+) T cells which react to the Leishmania major LACK antigen rapidly secrete interleukin-4 and are detrimental to the host in resistant BIO.D2 mice
-
JULIA V, GLAICHENHAUS N: CD4(+) T cells which react to the Leishmania major LACK antigen rapidly secrete interleukin-4 and are detrimental to the host in resistant BIO.D2 mice. Infect. Immun. (1999) 67(7):3641-3644.
-
(1999)
Infect. Immun.
, vol.67
, Issue.7
, pp. 3641-3644
-
-
Julia, V.1
Glaichenhaus, N.2
-
54
-
-
0036669784
-
Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo
-
STETSON DB, MOHRS M, MALLET-DESIGNE V, TEYTON L, LOCKSLEY RM: Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo. Immunity (2002) 17(2):191-200.
-
(2002)
Immunity
, vol.17
, Issue.2
, pp. 191-200
-
-
Stetson, D.B.1
Mohrs, M.2
Mallet-Designe, V.3
Teyton, L.4
Locksley, R.M.5
-
55
-
-
0026500979
-
IL-4 induces a Th2 response in Leishmania major-infected mice
-
CHATELAIN R, VARKILA K, COFFMAN RL: IL-4 induces a Th2 response in Leishmania major-infected mice. J. Immunol. (1992) 148(4):1182-1187.
-
(1992)
J. Immunol.
, vol.148
, Issue.4
, pp. 1182-1187
-
-
Chatelain, R.1
Varkila, K.2
Coffman, R.L.3
-
56
-
-
0027528795
-
Recombinant interleukin 12 cures mice infected with Leishmania major
-
HEINZEL FP, SCHOENHAUT DS, RERKO RM, ROSSER LE, GATELY MK: Recombinant interleukin 12 cures mice infected with Leishmania major. J. Exp. Med. (1993) 177(5):1505-1509.
-
(1993)
J. Exp. Med.
, vol.177
, Issue.5
, pp. 1505-1509
-
-
Heinzel, F.P.1
Schoenhaut, D.S.2
Rerko, R.M.3
Rosser, L.E.4
Gately, M.K.5
-
57
-
-
0033924551
-
Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice
-
HONDOWICZ BD, PARK AY, ELLOSO MM, SCOTT P: Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice. Eur. J. Immunol. (2000) 30(7):2007-2014.
-
(2000)
Eur. J. Immunol.
, vol.30
, Issue.7
, pp. 2007-2014
-
-
Hondowicz, B.D.1
Park, A.Y.2
Elloso, M.M.3
Scott, P.4
-
58
-
-
0033083947
-
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells
-
GROUX H, COTTREZ F, ROULEAU M et al.: A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells. J. Immunol. (1999) 162(3):1723-1729.
-
(1999)
J. Immunol.
, vol.162
, Issue.3
, pp. 1723-1729
-
-
Groux, H.1
Cottrez, F.2
Rouleau, M.3
-
59
-
-
0036232140
-
Administration of plasmids expressing interleukin-4 and interleukin-10 causes BALB/c mice to induce a T helper 2-type response despite the expected T helper 1-type response with a low-dose infection of Leishmania major
-
YAMAKAMI K, AKAO S, TADAKUMA T et al.: Administration of plasmids expressing interleukin-4 and interleukin-10 causes BALB/c mice to induce a T helper 2-type response despite the expected T helper 1-type response with a low-dose infection of Leishmania major. Immunology (2002) 105(4):515-523.
-
(2002)
Immunology
, vol.105
, Issue.4
, pp. 515-523
-
-
Yamakami, K.1
Akao, S.2
Tadakuma, T.3
-
60
-
-
0035863867
-
The role of IL-10 in promoting disease progression in leishmaniasis
-
KANE MM, MOSSER DM: The role of IL-10 in promoting disease progression in leishmaniasis. J. Immunol (2001) 166(2):1141-1147. This work demonstrates that IL-10 contributes to susceptibility to L. major in BALB/c mice.
-
(2001)
J. Immunol.
, vol.166
, Issue.2
, pp. 1141-1147
-
-
Kane, M.M.1
Mosser, D.M.2
-
61
-
-
0038560975
-
The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major
-
NOBEN-TRAUTH N, LIRA R, NAGASE H, PAUL WE, SACKS DL: The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major. J. Immunol. (2003) 170(10):5152-5158.
-
(2003)
J. Immunol.
, vol.170
, Issue.10
, pp. 5152-5158
-
-
Noben-Trauth, N.1
Lira, R.2
Nagase, H.3
Paul, W.E.4
Sacks, D.L.5
-
62
-
-
0028158318
-
Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection
-
REINER SL, ZHENG S, WANG ZE, STOWRING L, LOCKSLEY RM: Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J. Exp. Med. (1994) 179(2):447-456.
-
(1994)
J. Exp. Med.
, vol.179
, Issue.2
, pp. 447-456
-
-
Reiner, S.L.1
Zheng, S.2
Wang, Z.E.3
Stowring, L.4
Locksley, R.M.5
-
63
-
-
0028179230
-
Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
-
POWRIE F, CORREA-OLIVEIRA R, MAUZE S, COFFMAN RL: Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. (1994) 179(2):589-600. The first demonstration that regulatory T cells were involved in parasitic (L. major) infection.
-
(1994)
J. Exp. Med.
, vol.179
, Issue.2
, pp. 589-600
-
-
Powrie, F.1
Correa-Oliveira, R.2
Mauze, S.3
Coffman, R.L.4
-
64
-
-
0037105473
-
The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells
-
ASEFFA A, GUMY A, LAUNOIS P et al.: The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells. J. Immunol. (2002) 169(6):3232-3241. Provides the first demonstration that a Th2 response can be controlled by CD4+CD25+T cells. See also [66].
-
(2002)
J. Immunol.
, vol.169
, Issue.6
, pp. 3232-3241
-
-
Aseffa, A.1
Gumy, A.2
Launois, P.3
-
65
-
-
0037220923
-
CD4(+)CD25(+) Regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice
-
XU D, LIU H, KOMAI-KOMA M et al.: CD4(+)CD25(+) Regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J. Immunol. (2003) 170:394-399. See [64] and [66].
-
(2003)
J. Immunol.
, vol.170
, pp. 394-399
-
-
Xu, D.1
Liu, H.2
Komai-Koma, M.3
-
66
-
-
0019720353
-
Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted BALB/c nude mice
-
MITCHELL GF, CURTIS JM, SCOLLAY RG, HANDMAN E: Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted BALB/c nude mice. Aust. J. Exp. Biol Med. Sci. (1981) 59(Pt 5):539-554. References [64-66] demonstrate that during latency, parasite replication is under immune pressure.
-
(1981)
Aust. J. Exp. Biol Med. Sci.
, vol.59
, Issue.PART 5
, pp. 539-554
-
-
Mitchell, G.F.1
Curtis, J.M.2
Scollay, R.G.3
Handman, E.4
-
67
-
-
0033180491
-
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
-
ERNST B, LEE DS, CHANG JM, SPRENT J, SURH CD: The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity (1999) 11(2):173-181.
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 173-181
-
-
Ernst, B.1
Lee, D.S.2
Chang, J.M.3
Sprent, J.4
Surh, C.D.5
-
68
-
-
0022971335
-
The effect of post-bloodmeal nutrition of Phlebotomus papatasi on the transmission of Leishmania major
-
WARBURG A, SCHLEIN Y: The effect of post-bloodmeal nutrition of Phlebotomus papatasi on the transmission of Leishmania major. Am. J. Trop. Med. Hyg. (1986) 35(5):926-930.
-
(1986)
Am. J. Trop. Med. Hyg.
, vol.35
, Issue.5
, pp. 926-930
-
-
Warburg, A.1
Schlein, Y.2
-
69
-
-
0034661692
-
A natural model of Leishmania major infection reveals a prolonged 'silent' phase of parasite amplification in the skin before the onset of lesion formation and immunity
-
BELKAID Y, MENDEZ S, LIRA R et al.: A natural model of Leishmania major infection reveals a prolonged 'silent' phase of parasite amplification in the skin before the onset of lesion formation and immunity. J. Immunol. (2000) 165(2):969-977. The first description of the low-dose intradermal model of L. major infection.
-
(2000)
J. Immunol.
, vol.165
, Issue.2
, pp. 969-977
-
-
Belkaid, Y.1
Mendez, S.2
Lira, R.3
-
70
-
-
0034443233
-
Leishmania major reaches distant cutaneous sites where it persists transiently while persisting durably in the primary dermal site and its draining lymph node: A study with laboratory mice
-
NICOLAS L, SIDJANSKI S, COLLE JH, MILON G: Leishmania major reaches distant cutaneous sites where it persists transiently while persisting durably in the primary dermal site and its draining lymph node: a study with laboratory mice. Infect. Immun. (2000) 68(12):6561-6566.
-
(2000)
Infect. Immun.
, vol.68
, Issue.12
, pp. 6561-6566
-
-
Nicolas, L.1
Sidjanski, S.2
Colle, J.H.3
Milon, G.4
-
71
-
-
0032547859
-
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: Implications for the initiation of anti-Leishmania immunity
-
VON STEBUT E, BELKAID Y, JAKOB T, SACKS DL, UDEY MC: Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J. Exp Med. (1998) 188(8):1547-1552. This reference provides the first demonstration that L major activates dendritic cells.
-
(1998)
J. Exp Med.
, vol.188
, Issue.8
, pp. 1547-1552
-
-
Von Stebut, E.1
Belkaid, Y.2
Jakob, T.3
Sacks, D.L.4
Udey, M.C.5
-
72
-
-
0028949382
-
Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response
-
MOLL H, FLOHE S, ROLLINGHOFF M: Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response. Eur. J. Immunol. (1995) 25(3):693-699.
-
(1995)
Eur. J. Immunol.
, vol.25
, Issue.3
, pp. 693-699
-
-
Moll, H.1
Flohe, S.2
Rollinghoff, M.3
-
73
-
-
0035914841
-
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
-
BELKAID Y, HOFFMANN KF, MENDEZ S et al.: The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. (2001) 194(10):1497-1506. The demonstration that IL-10 is required for L. major latency.
-
(2001)
J. Exp. Med.
, vol.194
, Issue.10
, pp. 1497-1506
-
-
Belkaid, Y.1
Hoffmann, K.F.2
Mendez, S.3
-
74
-
-
0024812189
-
Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major
-
MULLER I, GARCIA-SANZ JA, TITUS R, BEHIN R, LOUIS J: Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major. Immunol Rev. (1989) 112:95-113.
-
(1989)
Immunol Rev.
, vol.112
, pp. 95-113
-
-
Muller, I.1
Garcia-Sanz, J.A.2
Titus, R.3
Behin, R.4
Louis, J.5
-
75
-
-
0029976423
-
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
-
STENGER S, DONHAUSER N, THURING H, ROLLINGHOFF M, BOGDAN C: Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J. Exp. Med. (1996) 183(4):1501-1514.
-
(1996)
J. Exp. Med.
, vol.183
, Issue.4
, pp. 1501-1514
-
-
Stenger, S.1
Donhauser, N.2
Thuring, H.3
Rollinghoff, M.4
Bogdan, C.5
-
76
-
-
0034682553
-
The role of antigen and IL-12 in sustaining Thl memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge
-
STOBIE L, GURUNATHAN S, PRUSSIN C et al.: The role of antigen and IL-12 in sustaining Thl memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge. Proc. Natl. Acad Sci. USA (2000) 97(15):8427-8432.
-
(2000)
Proc. Natl. Acad Sci. USA
, vol.97
, Issue.15
, pp. 8427-8432
-
-
Stobie, L.1
Gurunathan, S.2
Prussin, C.3
-
77
-
-
0027395378
-
Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: A possible hazard for the host
-
AEBISCHER T, MOODY SF, HANDMAN E: Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: a possible hazard for the host. Infect. Immun. (1993) 61(1):220-226. This paper provides the first demonstration that L. major can persist following clinical cure in a genetically resistant host.
-
(1993)
Infect. Immun.
, vol.61
, Issue.1
, pp. 220-226
-
-
Aebischer, T.1
Moody, S.F.2
Handman, E.3
-
78
-
-
0035871729
-
The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge
-
MENDEZ S, GURUNATHAN S, KAMHAWI S et al.: The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge. J. Immunol. (2001) 166(8):5122-5128.
-
(2001)
J. Immunol.
, vol.166
, Issue.8
, pp. 5122-5128
-
-
Mendez, S.1
Gurunathan, S.2
Kamhawi, S.3
-
79
-
-
0024372986
-
Immunity to experimental infection with Leishmania major, generation ofprotective L3T4+ T cell clones recognizing antigen(s) associated with live parasites
-
MULLER I, LOUIS JA: Immunity to experimental infection with Leishmania major, generation ofprotective L3T4+ T cell clones recognizing antigen(s) associated with live parasites. Eur. J. Immunol. (1989) 19(5):865-871.
-
(1989)
Eur. J. Immunol.
, vol.19
, Issue.5
, pp. 865-871
-
-
Muller, I.1
Louis, J.A.2
-
80
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
BELKAID Y, PICCIRILLO AC, MENDEZ S, SHEVACH EM, SACKS DL: CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature (2002) 420:502-507. This reference provides the first demonstration that CD4+CD25+ T cells are necessary for parasite latency.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, A.C.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
81
-
-
0026529405
-
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages
-
GAZZINELLI RT, OSWALD IP, JAMES SL, SHER A: IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. J. Immunol. (1992) 148(6):1792-1796. This work demonstrates that IL- 10 exposure renders macrophages incapable of killing pathogen.
-
(1992)
J. Immunol.
, vol.148
, Issue.6
, pp. 1792-1796
-
-
Gazzinelli, R.T.1
Oswald, I.P.2
James, S.L.3
Sher, A.4
-
83
-
-
0030021084
-
Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
-
CARRERA L, GAZZINELLI RT, BADOLATO R et al.: Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J. Exp. Med. (1996) 183 (2):515-526. This reference describes, for the first time, the selective inhibition of IL-12 on Leishmania sp. infected macrophages.
-
(1996)
J. Exp. Med.
, vol.183
, Issue.2
, pp. 515-526
-
-
Carrera, L.1
Gazzinelli, R.T.2
Badolato, R.3
-
84
-
-
0032538905
-
Development of a natural model of cutaneous leishmaniasis: Powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis
-
BELKAID Y, KAMHAWI S, MODI G et al.: Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis. J. Exp. Med. (1998) 188(10):1941-1953.
-
(1998)
J. Exp. Med.
, vol.188
, Issue.10
, pp. 1941-1953
-
-
Belkaid, Y.1
Kamhawi, S.2
Modi, G.3
-
85
-
-
0035893005
-
Immune elimination of Leishmania major in mice: Implications for immune memory, vaccination, and reactivation disease
-
UZONNA JE, WEI G, YURKOWSKI D, BRETSCHER P: Immune elimination of Leishmania major in mice: implications for immune memory, vaccination, and reactivation disease. J. Immunol. (2001) 167(12):6967-6974. This work provides the first demonstration that in a susceptible background, sterile cure is not compatible with maintenance of memory.
-
(2001)
J. Immunol.
, vol.167
, Issue.12
, pp. 6967-6974
-
-
Uzonna, J.E.1
Wei, G.2
Yurkowski, D.3
Bretscher, P.4
-
86
-
-
0031460674
-
Activation of autoreactive T cells by peptides from human pathogens
-
HAUSMANN S, WUCHERPFENNIG KW: Activation of autoreactive T cells by peptides from human pathogens. Curr. Opin. Immunol. (1997) 9(6):831-838.
-
(1997)
Curr. Opin. Immunol.
, vol.9
, Issue.6
, pp. 831-838
-
-
Hausmann, S.1
Wucherpfennig, K.W.2
-
87
-
-
0033089078
-
Influence of microbiota in experimental cutaneous leishmaniasis in Swiss mice
-
DE OLIVEIRA MR, TAFURI WL, NICOLI JR et al.: Influence of microbiota in experimental cutaneous leishmaniasis in Swiss mice. Rev. Int. Med. Trop. Sao Paula (1999) 41(2):87-94. This work demonstrates that the presence of gut flora influences the susceptibility to Leishmania infection.
-
(1999)
Rev. Int. Med. Trop. Sao Paula
, vol.41
, Issue.2
, pp. 87-94
-
-
De Oliveira, M.R.1
Tafuri, W.L.2
Nicoli, J.R.3
-
88
-
-
0034670017
-
Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major
-
JULIA V, MCSORLEY SS, MALHERBE L et al.: Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major. J. Immunol. (2000) 165(10):5637-5645.
-
(2000)
J. Immunol.
, vol.165
, Issue.10
, pp. 5637-5645
-
-
Julia, V.1
Mcsorley, S.S.2
Malherbe, L.3
-
89
-
-
0022642591
-
Higher frequency of Leishmania major-specific L3T4+ T cells in susceptible BALB/c as compared with resistant CBA mice
-
MILON G, TITUS RG, CEROTTINI JC, MARCHAL G, LOUIS JA: Higher frequency of Leishmania major-specific L3T4+ T cells in susceptible BALB/c as compared with resistant CBA mice. J. Immunol. (1986) 136(4):1467-1471.
-
(1986)
J. Immunol.
, vol.136
, Issue.4
, pp. 1467-1471
-
-
Milon, G.1
Titus, R.G.2
Cerottini, J.C.3
Marchal, G.4
Louis, J.A.5
-
90
-
-
0036176155
-
IFN-gamma-producing CD45RA+CD8+ and IL-10-producing CD45RA-CD4+ T cells generated in response to LACK in naive subjects never exposed to Leishmania
-
BOURREAU E, COLLET M, PREVOT G et al.: IFN-gamma-producing CD45RA+CD8+ and IL-10-producing CD45RA-CD4+ T cells generated in response to LACK in naive subjects never exposed to Leishmania. Eur. J. Immunol. (2002) 32(2):510-520.
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.2
, pp. 510-520
-
-
Bourreau, E.1
Collet, M.2
Prevot, G.3
-
91
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
comment
-
CARAMALHO I, LOPES-CARVALHO T, OSTLER D et al.: Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. [comment]. J. Exp. Med (2003) 197(4):403-411. This reference demonstrates that CD4+CD25+ T cell function can be regulated through TLR.
-
(2003)
J. Exp. Med.
, vol.197
, Issue.4
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
-
92
-
-
0027159096
-
In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma
-
KARP CL, EL-SAFI SH, WYNN TA et al.: In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma. J. Clin. Invest. (1993) 91(4):1644-1648.
-
(1993)
J. Clin. Invest.
, vol.91
, Issue.4
, pp. 1644-1648
-
-
Karp, C.L.1
El-Safi, S.H.2
Wynn, T.A.3
-
93
-
-
0036839677
-
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy
-
MURRAY HW, LU CM, MAUZE S et al.: Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy. Infect. Immun. (2002) 70(11):6284-6293.
-
(2002)
Infect. Immun.
, vol.70
, Issue.11
, pp. 6284-6293
-
-
Murray, H.W.1
Lu, C.M.2
Mauze, S.3
-
94
-
-
0026783494
-
Transforming growth factor-beta in leishmanial infection: A parasite escape mechanism
-
BARRAL-NETTO M, BARRAL A, BROWNELL CE et al.: Transforming growth factor-beta in leishmanial infection: a parasite escape mechanism. Science (1992) 257(5069):545-548.
-
(1992)
Science
, vol.257
, Issue.5069
, pp. 545-548
-
-
Barral-Netto, M.1
Barral, A.2
Brownell, C.E.3
-
95
-
-
0028970948
-
Transforming growth factor-beta in human cutaneous leishmaniasis
-
BARRAL A, TEIXEIRA M, REIS P et al.: Transforming growth factor-beta in human cutaneous leishmaniasis. Am. J. Pathol. (1995) 147(4):947-954.
-
(1995)
Am. J. Pathol.
, vol.147
, Issue.4
, pp. 947-954
-
-
Barral, A.1
Teixeira, M.2
Reis, P.3
-
96
-
-
0032402259
-
The importance of TGF-beta in murine visceral leishmaniasis
-
WILSON ME, YOUNG BM, DAVIDSON BL, MENTE KA, MCGOWAN SE: The importance of TGF-beta in murine visceral leishmaniasis. J. Immunol. (1998) 161(11):6148-6155.
-
(1998)
J. Immunol.
, vol.161
, Issue.11
, pp. 6148-6155
-
-
Wilson, M.E.1
Young, B.M.2
Davidson, B.L.3
Mente, K.A.4
Mcgowan, S.E.5
-
97
-
-
0033555789
-
Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production
-
LI J, HUNTER CA, FARRELL JP: Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production. J. Immunol. (1999) 162(2):974-979.
-
(1999)
J. Immunol.
, vol.162
, Issue.2
, pp. 974-979
-
-
Li, J.1
Hunter, C.A.2
Farrell, J.P.3
-
98
-
-
0034651999
-
TGF-beta mediates CTLA-4 suppression of cellular immunity in murine kalaazar
-
GOMES NA, GATTASS CR BARRETO-DE-SOUZA V, WILSON ME, DOSREIS GA: TGF-beta mediates CTLA-4 suppression of cellular immunity in murine kalaazar. J. Immunol. (2000) 164(4):2001-2008.
-
(2000)
J. Immunol.
, vol.164
, Issue.4
, pp. 2001-2008
-
-
Gomes, N.A.1
Gattass, C.R.2
Barreto-De-Souza, V.3
Wilson, M.E.4
Dosreis, G.A.5
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