Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

Oncogene

Volumn 18, Issue 3, 1999, Pages 813-822

  Hoshino, Rika ^a   Chatani, Yuji ^b   Yamori, Takao ^c   Tsuruo, Takashi ^c,d   Oka, Hiroya ^e   Yoshida, Osamu ^e   Shimada, Yutaka ^e   Ari I, Shigeki ^e   Wada, Hiromi ^e   Fujimoto, Jiro ^f   Kohno, Michiaki ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^c CANCER CHEMOTHERAPY CENTER   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e KYOTO UNIVERSITY   (Japan)

^f HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

41 43 kDA map kinases (ERKs); Aberrant activation; Carcinogenesis; Human tumor; MEK

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN;

ARTICLE; BRAIN; COLON; CONTROLLED STUDY; ENZYME ACTIVATION; ESOPHAGUS; HEMATOPOIETIC SYSTEM; HUMAN; HUMAN CELL; KIDNEY; LIVER; LUNG; ONCOGENE RAS; OVARY; PANCREAS; POINT MUTATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH; TISSUE SPECIFICITY; TUMOR;

AMINO ACID SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; ENZYME ACTIVATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; NEOPLASMS; PROTEIN KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0033590636     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202367     Document Type: Article

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