-
2
-
-
0028293931
-
Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1
-
Alessi DR, Saito Y, Campbell DG et al (1994) Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. EMBO Journal 13 1610-1619
-
(1994)
EMBO Journal
, vol.13
, pp. 1610-1619
-
-
Alessi, D.R.1
Saito, Y.2
Campbell, D.G.3
-
3
-
-
0029099408
-
Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf
-
Alessi DR, Cohen P, Ashworth A, Cowley S, Leevers SJ and Marshall CJ (1995) Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf. Methods in Enzymology 255 279-290
-
(1995)
Methods in Enzymology
, vol.255
, pp. 279-290
-
-
Alessi, D.R.1
Cohen, P.2
Ashworth, A.3
Cowley, S.4
Leevers, S.J.5
Marshall, C.J.6
-
4
-
-
0025011812
-
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the Raf-1 proto-oncogene product
-
Baccarini M, Sabatini DM, App H, Rapp UR and Stanley ER (1990) Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the Raf-1 proto-oncogene product. EMBO Journal 9 3649-3657
-
(1990)
EMBO Journal
, vol.9
, pp. 3649-3657
-
-
Baccarini, M.1
Sabatini, D.M.2
App, H.3
Rapp, U.R.4
Stanley, E.R.5
-
5
-
-
0028229715
-
A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway
-
Ben LR, Paterson HF, Marshall CJ and Yarden Y (1994) A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway. EMBO Journal 13 3302-3311
-
(1994)
EMBO Journal
, vol.13
, pp. 3302-3311
-
-
Ben, L.R.1
Paterson, H.F.2
Marshall, C.J.3
Yarden, Y.4
-
6
-
-
0028839220
-
Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes
-
Bogoyevitch MA, Marshall CJ and Sugden PH (1995) Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes. Journal of Biological Chemistry 270 1-8
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 1-8
-
-
Bogoyevitch, M.A.1
Marshall, C.J.2
Sugden, P.H.3
-
7
-
-
0029166558
-
BCR and RAF form a complex in vivo via 14-3-3 proteins
-
Braselmann S and McCormick F (1995) BCR and RAF form a complex in vivo via 14-3-3 proteins. EMBO Journal 14 4839-4848
-
(1995)
EMBO Journal
, vol.14
, pp. 4839-4848
-
-
Braselmann, S.1
McCormick, F.2
-
9
-
-
0026596576
-
Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase
-
Bruder JT, Heidecker G and Rapp UR (1992) Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase. Genes and Development 6 545-556
-
(1992)
Genes and Development
, vol.6
, pp. 545-556
-
-
Bruder, J.T.1
Heidecker, G.2
Rapp, U.R.3
-
10
-
-
0027489748
-
Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways
-
Burgering BMT, De Vries Smits AMM, Medema RH, Van Weeren PC, Tertoolen LGJ and Bos JL (1993) Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways. Molecular and Cellular Biology 13 7248-7256
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 7248-7256
-
-
Burgering, B.M.T.1
De Vries Smits, A.M.M.2
Medema, R.H.3
Van Weeren, P.C.4
Tertoolen, L.G.J.5
Bos, J.L.6
-
11
-
-
0028924793
-
Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macro-phages
-
Buscher D, Hipskind RA, Krautwald S, Reimann T and Baccarini M (1995) Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macro-phages. Molecular and Cellular Biology 15 466-475
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 466-475
-
-
Buscher, D.1
Hipskind, R.A.2
Krautwald, S.3
Reimann, T.4
Baccarini, M.5
-
12
-
-
0029150470
-
Ser-3 is important for regulating Mos interaction with and stimulation of mitogen-activated protein kinase kinase
-
Chen MJA (1995) Ser-3 is important for regulating Mos interaction with and stimulation of mitogen-activated protein kinase kinase. Molecular and Cellular Biology 15 4727-4734
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 4727-4734
-
-
Chen, M.J.A.1
-
13
-
-
0029018737
-
Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase
-
Chow YH, Pumiglia K, Jun TH, Dent P, Sturgill TW and Jove R (1995) Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase. Journal of Biological Chemistry 270 14100-14106
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 14100-14106
-
-
Chow, Y.H.1
Pumiglia, K.2
Jun, T.H.3
Dent, P.4
Sturgill, T.W.5
Jove, R.6
-
14
-
-
0027716596
-
Inhibition of cAMP of Ras-dependent activation of Raf
-
Cook SJ and McCormick F (1993) Inhibition of cAMP of Ras-dependent activation of Raf. Science 262 1069-1072
-
(1993)
Science
, vol.262
, pp. 1069-1072
-
-
Cook, S.J.1
McCormick, F.2
-
15
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathways
-
Coso OA, Chiariello M, Yu JC et al (1995) The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathways. Cell 81 1137-1146
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.C.3
-
16
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH3T3 cells
-
Cowley S, Paterson H, Kemp P and Marshall CJ (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH3T3 cells. Cell 77 841-852
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
17
-
-
0027978816
-
The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: Evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
-
Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS and Cohen P (1994) The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochemical Journal 303 21-26
-
(1994)
Biochemical Journal
, vol.303
, pp. 21-26
-
-
Cross, D.A.1
Alessi, D.R.2
Vandenheede, J.R.3
McDowell, H.E.4
Hundal, H.S.5
Cohen, P.6
-
18
-
-
0028169624
-
Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed and serum-stimulated fibroblasts
-
Dent P and Sturgill TW (1994) Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed and serum-stimulated fibroblasts. Proceedings of the National Academy of Sciences of the USA 91 9544-9548
-
(1994)
Proceedings of the National Academy of Sciences of the USA
, vol.91
, pp. 9544-9548
-
-
Dent, P.1
Sturgill, T.W.2
-
19
-
-
0029014973
-
Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases
-
Dent P, Jelinek T, Morrison DK, Weber M and Sturgill TW (1995a) Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases. Science 268 1902-1906
-
(1995)
Science
, vol.268
, pp. 1902-1906
-
-
Dent, P.1
Jelinek, T.2
Morrison, D.K.3
Weber, M.4
Sturgill, T.W.5
-
20
-
-
0029042701
-
Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro
-
Dent P, Reardon DB, Morrison DK and Sturgill TW (1995b) Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro. Molecular and Cellular Biology 15 4125-4135
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 4125-4135
-
-
Dent, P.1
Reardon, D.B.2
Morrison, D.K.3
Sturgill, T.W.4
-
21
-
-
10244266479
-
Involvement of p21Ras in activation of extracellular signal-regulated kinase 2
-
De Vries Smits AM, Burgering BM, Leevers SJ, Marshall CJ and Bos JL (1992) Involvement of p21Ras in activation of extracellular signal-regulated kinase 2. Nature 360 305
-
(1992)
Nature
, vol.360
, pp. 305
-
-
De Vries Smits, A.M.1
Burgering, B.M.2
Leevers, S.J.3
Marshall, C.J.4
Bos, J.L.5
-
22
-
-
0026679892
-
Raf functions downstream of Ras1 in the sevenless signal transduction pathway
-
Dickson B, Sprenger F, Morrison D and Hafen E (1992) Raf functions downstream of Ras1 in the sevenless signal transduction pathway. Nature 360 600-603
-
(1992)
Nature
, vol.360
, pp. 600-603
-
-
Dickson, B.1
Sprenger, F.2
Morrison, D.3
Hafen, E.4
-
23
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley DT, Pang L, Decker SJ, Bridges AJ and Saltiel AR (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proceedings of the National Academy of Sciences of the USA 92 7686-7689
-
(1995)
Proceedings of the National Academy of Sciences of the USA
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
24
-
-
0027364980
-
Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
-
Fabian JR, Daar IO and Morrison DK (1993a) Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Molecular and Cellular Biology 13 7170-7179
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 7170-7179
-
-
Fabian, J.R.1
Daar, I.O.2
Morrison, D.K.3
-
25
-
-
0027184473
-
Requirements for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
-
Fabian JR, Morrison DK and Daar IO (1993b) Requirements for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes. Journal Cellular Biology 122 645-652
-
(1993)
Journal Cellular Biology
, vol.122
, pp. 645-652
-
-
Fabian, J.R.1
Morrison, D.K.2
Daar, I.O.3
-
27
-
-
0023715225
-
Inhibition of NIH3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP
-
Feig LA and Cooper GM (1988) Inhibition of NIH3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP, Molecular Cellular Biology 68 3235-3243
-
(1988)
Molecular Cellular Biology
, vol.68
, pp. 3235-3243
-
-
Feig, L.A.1
Cooper, G.M.2
-
28
-
-
0028011013
-
Enzymatic characteristics of the c-Raf-1 protein kinase
-
Force T, Bonventre JV, Heidecker G, Rapp U, Avruch J and Kyriakis JM (1994) Enzymatic characteristics of the c-Raf-1 protein kinase. Proceedings of the National Academy of Sciences of the USA 91 1270-1274
-
(1994)
Proceedings of the National Academy of Sciences of the USA
, vol.91
, pp. 1270-1274
-
-
Force, T.1
Bonventre, J.V.2
Heidecker, G.3
Rapp, U.4
Avruch, J.5
Kyriakis, J.M.6
-
29
-
-
0028073606
-
Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
-
Freed E, Symons M, Macdonald SG, McCormick F and Ruggieri R (1994) Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science 265 1713-1716
-
(1994)
Science
, vol.265
, pp. 1713-1716
-
-
Freed, E.1
Symons, M.2
Macdonald, S.G.3
McCormick, F.4
Ruggieri, R.5
-
30
-
-
0028115999
-
Interaction of the protein kinase Raf-1 with 14-3-3 proteins
-
Fu H, Xia K, Pallas DC et al (1994) Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science 266 126-129
-
(1994)
Science
, vol.266
, pp. 126-129
-
-
Fu, H.1
Xia, K.2
Pallas, D.C.3
-
31
-
-
0029042689
-
Raf1 interaction with Cdc 25 phosphatase ties mitogenic signal transduction to cell cycle activation
-
Galaktionov K, Jessus C and Beach D (1995) Raf1 interaction with Cdc 25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes and Development 9 1046-1058
-
(1995)
Genes and Development
, vol.9
, pp. 1046-1058
-
-
Galaktionov, K.1
Jessus, C.2
Beach, D.3
-
32
-
-
0026701092
-
Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells
-
Gallego C, Gupta SK, Heasley LE, Qian NX and Johnson GL (1992) Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells. Proceedings of the National Academy of Sciences of the USA 89 7355-7359
-
(1992)
Proceedings of the National Academy of Sciences of the USA
, vol.89
, pp. 7355-7359
-
-
Gallego, C.1
Gupta, S.K.2
Heasley, L.E.3
Qian, N.X.4
Johnson, G.L.5
-
33
-
-
0027171138
-
Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase on-coproteins
-
Gardner AM, Vaillancourt RR and Johnson GL (1993) Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase on-coproteins. Journol of Biological Chemistry 268 17896-17901
-
(1993)
Journol of Biological Chemistry
, vol.268
, pp. 17896-17901
-
-
Gardner, A.M.1
Vaillancourt, R.R.2
Johnson, G.L.3
-
34
-
-
0028073963
-
Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras
-
Ghosh S and Bell RM (1994) Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras. Journal of Biological Chemistry 269 30785-30788
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 30785-30788
-
-
Ghosh, S.1
Bell, R.M.2
-
35
-
-
0028083893
-
The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras
-
Ghosh S, Xie WQ, Quest AF, Mabrouk GM, Strum JC and Bell RM (1994) The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras. Journal of Biological Chemistry 269 10000-10007
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 10000-10007
-
-
Ghosh, S.1
Xie, W.Q.2
Quest, A.F.3
Mabrouk, G.M.4
Strum, J.C.5
Bell, R.M.6
-
36
-
-
0028331587
-
Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic
-
Gibbs JB, Oliff A and Kohl NE (1994) Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic. Cell 77 175-178
-
(1994)
Cell
, vol.77
, pp. 175-178
-
-
Gibbs, J.B.1
Oliff, A.2
Kohl, N.E.3
-
37
-
-
0028905076
-
Transcription factor ATF2 regulation by the JNK signal transduction pathway
-
Gupta S, Campbell D, Derijard B and Davis RJ (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267 389-393
-
(1995)
Science
, vol.267
, pp. 389-393
-
-
Gupta, S.1
Campbell, D.2
Derijard, B.3
Davis, R.J.4
-
40
-
-
0027263251
-
C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation
-
Han M, Golden A, Han Y and Sternberg PW (1993) C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation. Nature 363 133-140
-
(1993)
Nature
, vol.363
, pp. 133-140
-
-
Han, M.1
Golden, A.2
Han, Y.3
Sternberg, P.W.4
-
41
-
-
0026037624
-
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins
-
Hancock JF, Cadwaller K, Paterson H and Marshall CJ (1991) A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins. EMBO Journal 10 4033-4039
-
(1991)
EMBO Journal
, vol.10
, pp. 4033-4039
-
-
Hancock, J.F.1
Cadwaller, K.2
Paterson, H.3
Marshall, C.J.4
-
42
-
-
0028359636
-
Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf
-
Haystead CMM, Gregory P, Shirazi A et al (1994) Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf. Journal of Biological Chemistry 269 12804-12808
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 12804-12808
-
-
Haystead, C.M.M.1
Gregory, P.2
Shirazi, A.3
-
43
-
-
0028795913
-
Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase
-
Herrmann C, Martin GA and Wittinghofer A (1995) Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase. Journal of Biological Chemistry 270 2901-2905
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 2901-2905
-
-
Herrmann, C.1
Martin, G.A.2
Wittinghofer, A.3
-
44
-
-
0027423418
-
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi M, Lin A, Smeal T, Minden A and Karin M (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes and Development 7 2135-2148
-
(1993)
Genes and Development
, vol.7
, pp. 2135-2148
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
45
-
-
0028947685
-
The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway
-
Hou XS, Chou TB, Melnick MB and Perrimon N (1995) The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell 81 63-71
-
(1995)
Cell
, vol.81
, pp. 63-71
-
-
Hou, X.S.1
Chou, T.B.2
Melnick, M.B.3
Perrimon, N.4
-
46
-
-
0026754369
-
Activation of the MAP kinase pathway by the protein kinase raf
-
Howe LR, Leevers SJ, Gómez N, Nakielny S, Cohen P and Marshall CJ (1992) Activation of the MAP kinase pathway by the protein kinase raf. Cell 71 335-342
-
(1992)
Cell
, vol.71
, pp. 335-342
-
-
Howe, L.R.1
Leevers, S.J.2
Gómez, N.3
Nakielny, S.4
Cohen, P.5
Marshall, C.J.6
-
47
-
-
0028051904
-
Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase
-
Irie K, Gotoh Y, Yashar BM, Errede B, Nishida E and Matsumoto K (1994) Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase. Science 265 1716-1719
-
(1994)
Science
, vol.265
, pp. 1716-1719
-
-
Irie, K.1
Gotoh, Y.2
Yashar, B.M.3
Errede, B.4
Nishida, E.5
Matsumoto, K.6
-
48
-
-
0027447863
-
The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinase
-
Itoh T, Kaibuchi K, Masuda T et al (1993a) The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinase. Journal of Biological Chemistry 268 3025-3028
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 3025-3028
-
-
Itoh, T.1
Kaibuchi, K.2
Masuda, T.3
-
49
-
-
0027388945
-
A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase
-
Itoh T, Kaibuchi K, Masuda T et al (1993b) A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase. Proceedings of the National Academy of Sciences of the USA 90 975-979
-
(1993)
Proceedings of the National Academy of Sciences of the USA
, vol.90
, pp. 975-979
-
-
Itoh, T.1
Kaibuchi, K.2
Masuda, T.3
-
50
-
-
0029004353
-
Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo
-
Jamal S and ZiffEB (1995) Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo. Oncogene 10 2095-2101
-
(1995)
Oncogene
, vol.10
, pp. 2095-2101
-
-
Jamal, S.1
Ziff, E.B.2
-
51
-
-
0028000009
-
Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2
-
Janes PW, Daly RJ, deFazio A and Sutherland RL (1994) Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2. Oncogene 9 3601-3608
-
(1994)
Oncogene
, vol.9
, pp. 3601-3608
-
-
Janes, P.W.1
Daly, R.J.2
DeFazio, A.3
Sutherland, R.L.4
-
52
-
-
0029067231
-
Isoforms of 14-3-3 protein can form homoand heterodimers in vivo and in vitro: Implications for function as adapter proteins
-
Jones DH, Ley S and Aitken A (1995) Isoforms of 14-3-3 protein can form homoand heterodimers in vivo and in vitro: implications for function as adapter proteins. FEBS Letters 368 55-58
-
(1995)
FEBS Letters
, vol.368
, pp. 55-58
-
-
Jones, D.H.1
Ley, S.2
Aitken, A.3
-
53
-
-
0028559163
-
A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells
-
Kabarowski JH, Allen PB and Wiedemann LM (1994) A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells. EMBO Journal 13 5887-5895
-
(1994)
EMBO Journal
, vol.13
, pp. 5887-5895
-
-
Kabarowski, J.H.1
Allen, P.B.2
Wiedemann, L.M.3
-
54
-
-
0027964170
-
The post-translational modification of ras p21 is important for Raf-1 activation
-
Kikuchi A and Williams LT (1994) The post-translational modification of ras p21 is important for Raf-1 activation. Journal of Biological Chemistry 269 20054-20059
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 20054-20059
-
-
Kikuchi, A.1
Williams, L.T.2
-
55
-
-
0027133230
-
Raf-1 is not a major upstream regulator of MAP kinases in rat fibroblasts
-
Kizaka-Kondoh S and Okayama H (1993) Raf-1 is not a major upstream regulator of MAP kinases in rat fibroblasts. FEBS Letters 336 255-258
-
(1993)
FEBS Letters
, vol.336
, pp. 255-258
-
-
Kizaka-Kondoh, S.1
Okayama, H.2
-
57
-
-
0025979335
-
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
-
Kolch W, Heidecker G, Lloyd P and Rapp UR (1991) Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature 349 426-428
-
(1991)
Nature
, vol.349
, pp. 426-428
-
-
Kolch, W.1
Heidecker, G.2
Lloyd, P.3
Rapp, U.R.4
-
58
-
-
0027326410
-
Protein kinase Cα activates Raf-1 by direct phosphorylation
-
Kolch W, Heidecker G, Kochs G et al (1993) Protein kinase Cα activates Raf-1 by direct phosphorylation. Nature 364 249-252
-
(1993)
Nature
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
-
59
-
-
0028958188
-
The membrane immunoglobulin receptor utilizes a Shc/Grb2/hSOS complex for activation of the mitogen-activated protein kinase cascade in a B-cell line
-
Kumar G, Wang S, Gupta S and Nel A (1995) The membrane immunoglobulin receptor utilizes a Shc/Grb2/hSOS complex for activation of the mitogen-activated protein kinase cascade in a B-cell line. Biochemical Journal 307 215-223
-
(1995)
Biochemical Journal
, vol.307
, pp. 215-223
-
-
Kumar, G.1
Wang, S.2
Gupta, S.3
Nel, A.4
-
60
-
-
0028074621
-
Ras-dependent growth factor regulation of MEK kinase in PC12 cells
-
Lange-Carter CA and Johnson GL (1994) Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science 265 1458-1461
-
(1994)
Science
, vol.265
, pp. 1458-1461
-
-
Lange-Carter, C.A.1
Johnson, G.L.2
-
61
-
-
0027215820
-
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
-
Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ and Johnson GL (1993) A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science 260 315-319
-
(1993)
Science
, vol.260
, pp. 315-319
-
-
Lange-Carter, C.A.1
Pleiman, C.M.2
Gardner, A.M.3
Blumer, K.J.4
Johnson, G.L.5
-
62
-
-
0028272507
-
Requirement for Ras in Raf activation is over-come by targeting Raf to the plasma membrane
-
Leevers SJ, Paterson HF and Marshall CJ (1994) Requirement for Ras in Raf activation is over-come by targeting Raf to the plasma membrane. Nature 369 411-414
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
63
-
-
0027253407
-
Detection of c-mos proto-oncogene expression in human cells
-
Li CC, Chen E, O'Connell CD and Longo DL (1993) Detection of c-mos proto-oncogene expression in human cells. Oncogene 8 1685-1691
-
(1993)
Oncogene
, vol.8
, pp. 1685-1691
-
-
Li, C.C.1
Chen, E.2
O'Connell, C.D.3
Longo, D.L.4
-
64
-
-
0027482547
-
Raf-1 protein kinase activates the NF-kB transcription factor by dissociating the cytoplasmic NF-κB-IκB complex
-
Li S and Sedivy JM (1993) Raf-1 protein kinase activates the NF-kB transcription factor by dissociating the cytoplasmic NF-κB-IκB complex. Proceedings of the National Academy of Sciences of the USA 90 9247-9251
-
(1993)
Proceedings of the National Academy of Sciences of the USA
, vol.90
, pp. 9247-9251
-
-
Li, S.1
Sedivy, J.M.2
-
65
-
-
0028901576
-
Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins
-
Li S, Janosch P, Tanji M et al (1995) Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins. EMBO Journal 14 685-696
-
(1995)
EMBO Journal
, vol.14
, pp. 685-696
-
-
Li, S.1
Janosch, P.2
Tanji, M.3
-
66
-
-
0029034251
-
ATF-2 contains a phosphorylation-dependent transcriptional activation domain
-
Livingstone C, Patel G and Jones N (1995) ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO Journal 14 1785-1797
-
(1995)
EMBO Journal
, vol.14
, pp. 1785-1797
-
-
Livingstone, C.1
Patel, G.2
Jones, N.3
-
67
-
-
0027012928
-
c-erbB2 amplification and overexpression in human tumors
-
Lofts FJ and Gullick WJ (1992) c-erbB2 amplification and overexpression in human tumors. Cancer Treatment and Research 61 161-179
-
(1992)
Cancer Treatment and Research
, vol.61
, pp. 161-179
-
-
Lofts, F.J.1
Gullick, W.J.2
-
68
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour SJ, Matten WT, Hermann AS et al (1994) Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265 966-970
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
-
69
-
-
0027297647
-
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
-
Marais R, Wynne J and Treismann R (1993) The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73 381-393
-
(1993)
Cell
, vol.73
, pp. 381-393
-
-
Marais, R.1
Wynne, J.2
Treismann, R.3
-
70
-
-
0029006126
-
Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation
-
Marais R, Light Y, Paterson HF and Marshall CJ (1995) Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO Journal 14 3136-3145
-
(1995)
EMBO Journal
, vol.14
, pp. 3136-3145
-
-
Marais, R.1
Light, Y.2
Paterson, H.F.3
Marshall, C.J.4
-
71
-
-
0027996763
-
Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: Reconstitution of the signalling pathway in vitro
-
Marquardt B, Frith D and Stabel S (1994) Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: reconstitution of the signalling pathway in vitro. Oncogene 9 3213-3218
-
(1994)
Oncogene
, vol.9
, pp. 3213-3218
-
-
Marquardt, B.1
Frith, D.2
Stabel, S.3
-
72
-
-
0028872649
-
Specificity of receptor tyrosine kinase signalling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall CJ (1995) Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80 179-185
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
73
-
-
0027513768
-
Phosphorylation of Xenapus mitogen-activated protein (MAP) kinase kinase by MAP kinase kinase kinase and MAP kinase
-
Matsuda S, Gotoh Y and Nishida E (1993) Phosphorylation of Xenapus mitogen-activated protein (MAP) kinase kinase by MAP kinase kinase kinase and MAP kinase. Journal of Biological Chemistry 268 3277-3281
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 3277-3281
-
-
Matsuda, S.1
Gotoh, Y.2
Nishida, E.3
-
74
-
-
0029079325
-
Activation of protein kinase cascades by osmotic shock
-
Matsuda S, Kawasaki H, Moriguchi T, Gotoh Y and Nishida E (1995) Activation of protein kinase cascades by osmotic shock. Journal of Biological Chemistry 270 12781-12786
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 12781-12786
-
-
Matsuda, S.1
Kawasaki, H.2
Moriguchi, T.3
Gotoh, Y.4
Nishida, E.5
-
75
-
-
0029071689
-
14-3-3 is not essential for Raf-1 function: Identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner
-
Michaud NR, Fabian JR, Mathes KD and Morrison DK (1995) 14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner. Molecular and Cellular Biology 15 3390-3397
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 3390-3397
-
-
Michaud, N.R.1
Fabian, J.R.2
Mathes, K.D.3
Morrison, D.K.4
-
76
-
-
0028568217
-
Differential activation of ERK and JNK MAP kinases by Raf-1 and MEKK
-
Minden A, McMahon M, Lange-Carter C et al (1994) Differential activation of ERK and JNK MAP kinases by Raf-1 and MEKK. Science 266 1719-1723
-
(1994)
Science
, vol.266
, pp. 1719-1723
-
-
Minden, A.1
McMahon, M.2
Lange-Carter, C.3
-
77
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPase Rac and Cdc42Hs
-
Minden A, Lin A, Claret FX, Abo A and Karin M (1995) Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPase Rac and Cdc42Hs. Cell 81 1147-1157
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.X.3
Abo, A.4
Karin, M.5
-
78
-
-
0028956874
-
Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1, D-Phe5, D-Trp7, 9, Leu11] substance P
-
Mitchell FM, Heasley LE, Qian NX, Zamarripa J and Johnson GL (1995) Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1, D-Phe5, D-Trp7, 9, Leu11] substance P.Journal of Biological Chemistry 270 8623-8628
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 8623-8628
-
-
Mitchell, F.M.1
Heasley, L.E.2
Qian, N.X.3
Zamarripa, J.4
Johnson, G.L.5
-
79
-
-
0027337519
-
Complexes of Ras GTP with Raf-1 and mitogen-activated protein kinase kinase
-
Moodie SA, Willumsen BM, Weber MJ and Wolfman A (1993) Complexes of Ras GTP with Raf-1 and mitogen-activated protein kinase kinase. Science 260 1658-1661
-
(1993)
Science
, vol.260
, pp. 1658-1661
-
-
Moodie, S.A.1
Willumsen, B.M.2
Weber, M.J.3
Wolfman, A.4
-
80
-
-
0024382967
-
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor
-
Morrison DK, Kaplan DR, Escobedo JA, Rapp UR, Roberts TM and Williams LT (1989) Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell 58 649-657
-
(1989)
Cell
, vol.58
, pp. 649-657
-
-
Morrison, D.K.1
Kaplan, D.R.2
Escobedo, J.A.3
Rapp, U.R.4
Roberts, T.M.5
Williams, L.T.6
-
82
-
-
0027190850
-
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos
-
Muslin AJ, MacNicol AM and Williams LT (1993) Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos. Molecular and Cellular Biology 13 4197-4202
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 4197-4202
-
-
Muslin, A.J.1
MacNicol, A.M.2
Williams, L.T.3
-
83
-
-
0029107760
-
The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
-
Nassar N, Horn G, Herrmann C, Scherer A, McCormick F and Wittinghofer A (1995) The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature 375 554-560
-
(1995)
Nature
, vol.375
, pp. 554-560
-
-
Nassar, N.1
Horn, G.2
Herrmann, C.3
Scherer, A.4
McCormick, F.5
Wittinghofer, A.6
-
84
-
-
0027299967
-
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs
-
Nebreda AR and Hunt T (1993) The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs. EMBO Journal 12 1979-1986
-
(1993)
EMBO Journal
, vol.12
, pp. 1979-1986
-
-
Nebreda, A.R.1
Hunt, T.2
-
85
-
-
0026591788
-
Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-ras
-
Nori M, L'Allemain G and Weber MJ (1992) Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-ras. Molecular and Cellular Biology 12 936-945
-
(1992)
Molecular and Cellular Biology
, vol.12
, pp. 936-945
-
-
Nori, M.1
L'Allemain, G.2
Weber, M.J.3
-
86
-
-
0029080247
-
Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma
-
Oka H, Chatani Y, Hoshino R et al (1995) Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma. Cancer Research 55 4182-4187
-
(1995)
Cancer Research
, vol.55
, pp. 4182-4187
-
-
Oka, H.1
Chatani, Y.2
Hoshino, R.3
-
87
-
-
0029101360
-
An essential role for Rho, Rac and Cdc42 GTPases in cell cycle progression through G1
-
Olson MF, Ashworth A and Hall A (1995) An essential role for Rho, Rac and Cdc42 GTPases in cell cycle progression through G1. Science 269 1270-1272
-
(1995)
Science
, vol.269
, pp. 1270-1272
-
-
Olson, M.F.1
Ashworth, A.2
Hall, A.3
-
88
-
-
0027935136
-
Association of polyomavirus middle tumor antigen with 14-3-3 proteins
-
Pallas DC, Fu H, Haehnel LC, Weller W, Collier RJ and Roberts TM (1994) Association of polyomavirus middle tumor antigen with 14-3-3 proteins. Science 265 535-537
-
(1994)
Science
, vol.265
, pp. 535-537
-
-
Pallas, D.C.1
Fu, H.2
Haehnel, L.C.3
Weller, W.4
Collier, R.J.5
Roberts, T.M.6
-
89
-
-
0029034774
-
Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
-
Pang L, Sawada T, Decker SJ and Saltiel AR (1995) Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. Journal of Biological Chemistry 270 13585-13588
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 13585-13588
-
-
Pang, L.1
Sawada, T.2
Decker, S.J.3
Saltiel, A.R.4
-
91
-
-
0028223704
-
Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells
-
Porras A, Muszynski K, Rapp UR and Santos E (1994) Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells. Journal of Biological Chemistry 269 12741-12748
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 12741-12748
-
-
Porras, A.1
Muszynski, K.2
Rapp, U.R.3
Santos, E.4
-
92
-
-
0027462979
-
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro
-
Posada J, Yew N, Ahn NG, Vande Woude GF and Cooper JA (1993) Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. Molecular and Cellular Biology 13 2546-2553
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 2546-2553
-
-
Posada, J.1
Yew, N.2
Ahn, N.G.3
Vande Woude, G.F.4
Cooper, J.A.5
-
93
-
-
0028318136
-
Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton
-
Prendergast GC, Davide JP, deSolms SJ et al (1994) Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton. Molecular and Cellular Biology 14 4193-202
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 4193-4202
-
-
Prendergast, G.C.1
Davide, J.P.2
DeSolms, S.J.3
-
94
-
-
0028970393
-
Raf-1 N-terminal sequences necessary for Ras-Raf interaction and signal transduction
-
Pumiglia K, Chow YH, Fabian J, Morrison D, Decker S and Jove R (1995) Raf-1 N-terminal sequences necessary for Ras-Raf interaction and signal transduction. Molecular and Cellular Biology 15 398-406
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 398-406
-
-
Pumiglia, K.1
Chow, Y.H.2
Fabian, J.3
Morrison, D.4
Decker, S.5
Jove, R.6
-
95
-
-
0028036746
-
Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes
-
Reimann T, Buscher D, Hipskind RA, Krautwald S, Lohmann-Matthes ML and Baccarini M (1994) Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes. Journal of Immunology 153 5740-5749
-
(1994)
Journal of Immunology
, vol.153
, pp. 5740-5749
-
-
Reimann, T.1
Buscher, D.2
Hipskind, R.A.3
Krautwald, S.4
Lohmann-Matthes, M.L.5
Baccarini, M.6
-
97
-
-
0028144704
-
R-ras interacts with rasGAP, neurofibromin and c-raf but does not regulate cell growth or differentiation
-
Rey I, Taylor-Harris P, VanErp H and Hall A (1994) R-ras interacts with rasGAP, neurofibromin and c-raf but does not regulate cell growth or differentiation. Oncogene 9 685-692
-
(1994)
Oncogene
, vol.9
, pp. 685-692
-
-
Rey, I.1
Taylor-Harris, P.2
VanErp, H.3
Hall, A.4
-
98
-
-
0028219853
-
Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation
-
Rossomando AJ, Dent P, Sturgill TW and Marshak DR (1994) Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation. Molecular and Cellular Biology 14 1594-1602
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 1594-1602
-
-
Rossomando, A.J.1
Dent, P.2
Sturgill, T.W.3
Marshak, D.R.4
-
99
-
-
0029077563
-
Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1)
-
Russell M, Lange CC and Johnson GL (1995) Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1). Journal of Biological Chemistry 270 11757-11760
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 11757-11760
-
-
Russell, M.1
Lange, C.C.2
Johnson, G.L.3
-
100
-
-
0028294622
-
Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity
-
Russell M, Winitz S and Johnson GL (1994) Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity. Molecular and Cellular Biology 14 2343-2351
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 2343-2351
-
-
Russell, M.1
Winitz, S.2
Johnson, G.L.3
-
101
-
-
0028284969
-
MAP kinase kinase is a physiological substrate for MAP kinase in rat phaeochromocytoma (PC12) cells
-
Saito Y, Gomez N, Campbell DG, Ashworth A, Marshall CJ and Cohen P (1994) MAP kinase kinase is a physiological substrate for MAP kinase in rat phaeochromocytoma (PC12) cells. FEBS Letters 341 119-124
-
(1994)
FEBS Letters
, vol.341
, pp. 119-124
-
-
Saito, Y.1
Gomez, N.2
Campbell, D.G.3
Ashworth, A.4
Marshall, C.J.5
Cohen, P.6
-
102
-
-
0030059508
-
Activation of MEK-1 and SEK-1 by the proto-oncogene Tpl-2: A novel MAP kinase kinase kinase
-
Salmeron A, Ahmad T, Carlile G, Pappin D, Narsimhan RP and Ley SC (1996) Activation of MEK-1 and SEK-1 by the proto-oncogene Tpl-2: a novel MAP kinase kinase kinase. EMBO Journal 15 817-826
-
(1996)
EMBO Journal
, vol.15
, pp. 817-826
-
-
Salmeron, A.1
Ahmad, T.2
Carlile, G.3
Pappin, D.4
Narsimhan, R.P.5
Ley, S.C.6
-
103
-
-
0027385030
-
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase
-
Samuels ML, Weber MJ, Bishop M and McMahon M (1993) Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase. Molecular Cellular Biology 13 6241-6252
-
(1993)
Molecular Cellular Biology
, vol.13
, pp. 6241-6252
-
-
Samuels, M.L.1
Weber, M.J.2
Bishop, M.3
McMahon, M.4
-
104
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez I, Hughes RT, Mayer BJ et al (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372 794-798
-
(1994)
Nature
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
-
105
-
-
0028987829
-
The human CCKB/gastrin receptor transfected into rat1 fibroblasts mediates activation of MAP kinase, p74raf-1 kinase and mitogenesis
-
Seufferlein T, Withers DJ, Broad S, Herget T, Walsh JH and Rozengurt E (1995) The human CCKB/gastrin receptor transfected into rat1 fibroblasts mediates activation of MAP kinase, p74raf-1 kinase and mitogenesis. Cell Growth and Differentiation 6 383-393
-
(1995)
Cell Growth and Differentiation
, vol.6
, pp. 383-393
-
-
Seufferlein, T.1
Withers, D.J.2
Broad, S.3
Herget, T.4
Walsh, J.H.5
Rozengurt, E.6
-
106
-
-
0022472990
-
Requirement for c-ras proteins during viral oncogene transformation
-
Smith MR, DeGubicus SJ and Stacey DW (1986) Requirement for c-ras proteins during viral oncogene transformation. Nature 320 540-543
-
(1986)
Nature
, vol.320
, pp. 540-543
-
-
Smith, M.R.1
DeGubicus, S.J.2
Stacey, D.W.3
-
107
-
-
0028175939
-
The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner
-
Spaargaren M, Martin GA, McCormick F, Femandez-Sarabia MJ and Bischoff JR (1994a) The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner. Biochemical Journal 300 303-307
-
(1994)
Biochemical Journal
, vol.300
, pp. 303-307
-
-
Spaargaren, M.1
Martin, G.A.2
McCormick, F.3
Femandez-Sarabia, M.J.4
Bischoff, J.R.5
-
108
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe D, Macdonald SG, Cadwallader K, Symons M and Hancock JF (1994) Activation of Raf as a result of recruitment to the plasma membrane. Science 264 1463-1467
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
109
-
-
0027527919
-
Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells
-
Traverse S, Cohen P, Paterson H, Marshall CJ, Rapp U and Grand RJA (1993) Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells. Oncogene 8 3175-3181
-
(1993)
Oncogene
, vol.8
, pp. 3175-3181
-
-
Traverse, S.1
Cohen, P.2
Paterson, H.3
Marshall, C.J.4
Rapp, U.5
Grand, R.J.A.6
-
110
-
-
0028270718
-
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation
-
Troppmair J, Bruder JT, Munoz H et al (1994) Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation. Journal of Biological Chemistry 269 7030-7035
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 7030-7035
-
-
Troppmair, J.1
Bruder, J.T.2
Munoz, H.3
-
112
-
-
0026101215
-
Expression of growth factor receptors in human brain tumours
-
Tuzi NL, Venter DJ, Kumar S, Staddon SL, Lemoine NR and Gullick WJ (1991) Expression of growth factor receptors in human brain tumours. British Journal of Cancer 63 227-233
-
(1991)
British Journal of Cancer
, vol.63
, pp. 227-233
-
-
Tuzi, N.L.1
Venter, D.J.2
Kumar, S.3
Staddon, S.L.4
Lemoine, N.R.5
Gullick, W.J.6
-
113
-
-
0027161398
-
Complex formation between RAS and RAF and other protein kinases
-
Van Aelst L, Barr M, Marcus S, Polverino A and Wigler M (1993) Complex formation between RAS and RAF and other protein kinases. Proceedings of the National Academy of Sciences of the USA 90 6213-6217
-
(1993)
Proceedings of the National Academy of Sciences of the USA
, vol.90
, pp. 6213-6217
-
-
Van Aelst, L.1
Barr, M.2
Marcus, S.3
Polverino, A.4
Wigler, M.5
-
114
-
-
0029030855
-
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
-
van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P and Angel P (1995) ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO Journal 14 1798-811
-
(1995)
EMBO Journal
, vol.14
, pp. 1798-1811
-
-
Van Dam, H.1
Wilhelm, D.2
Herr, I.3
Steffen, A.4
Herrlich, P.5
Angel, P.6
-
115
-
-
0027250250
-
Mammalian Ras interacts directly with the serine/threonine kinase Raf
-
Vojtek AB, Hollenberg SM and Cooper JA (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74 205-214
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojtek, A.B.1
Hollenberg, S.M.2
Cooper, J.A.3
-
116
-
-
0027200883
-
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
-
Warne PH, Viciana PR and Downward J (1993) Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature 364 352-355
-
(1993)
Nature
, vol.364
, pp. 352-355
-
-
Warne, P.H.1
Viciana, P.R.2
Downward, J.3
-
117
-
-
0029125757
-
Integration of MAP kinase signal transduction pathways at the serum response element
-
Whitmarsh AJ, Shore P, Sharrocks AD and Davis RJ (1995) Integration of MAP kinase signal transduction pathways at the serum response element. Science 269 403-407
-
(1995)
Science
, vol.269
, pp. 403-407
-
-
Whitmarsh, A.J.1
Shore, P.2
Sharrocks, A.D.3
Davis, R.J.4
-
118
-
-
0028986629
-
Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAP kinase kinase-dependent, c-Raf-1-independent fashion in mouse macro-phages
-
Winston BW, Lange-Carter CA, Gardner AM, Johnson GL and Riches DW (1995) Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAP kinase kinase-dependent, c-Raf-1-independent fashion in mouse macro-phages. Proceedings of the National Academy of Sciences of the USA 92 1614-1618
-
(1995)
Proceedings of the National Academy of Sciences of the USA
, vol.92
, pp. 1614-1618
-
-
Winston, B.W.1
Lange-Carter, C.A.2
Gardner, A.M.3
Johnson, G.L.4
Riches, D.W.5
-
119
-
-
0026523559
-
Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
-
Wood KW, Sarnecki C, Roberts TM and Blenis J (1992) Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68 1041-1050
-
(1992)
Cell
, vol.68
, pp. 1041-1050
-
-
Wood, K.W.1
Sarnecki, C.2
Roberts, T.M.3
Blenis, J.4
-
120
-
-
0027772672
-
Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′, 5′ -monophosphate
-
Wu J, Dent P, Jelinek T, Wolfman A, Weber MJ and Sturgill TW (1993) Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′, 5′ -monophosphate. Science 262 1065-1069
-
(1993)
Science
, vol.262
, pp. 1065-1069
-
-
Wu, J.1
Dent, P.2
Jelinek, T.3
Wolfman, A.4
Weber, M.J.5
Sturgill, T.W.6
-
121
-
-
0029058730
-
Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins
-
Yamamori B, Kuroda S, Shimizu K, Fukui K, Ohtsuka T and Takai Y (1995) Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins. Journal of Biological Chemistry 270 11723-11726
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 11723-11726
-
-
Yamamori, B.1
Kuroda, S.2
Shimizu, K.3
Fukui, K.4
Ohtsuka, T.5
Takai, Y.6
-
122
-
-
0028670788
-
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator, SEK1
-
Yan M, Dai T, Deak JC et al (1994) Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator, SEK1. Nature 320 798-801
-
(1994)
Nature
, vol.320
, pp. 798-801
-
-
Yan, M.1
Dai, T.2
Deak, J.C.3
-
123
-
-
0027337248
-
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
-
Zhang XF, Settleman J, Kyriakis JM et al (1993) Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature 364 308-313
-
(1993)
Nature
, vol.364
, pp. 308-313
-
-
Zhang, X.F.1
Settleman, J.2
Kyriakis, J.M.3
-
124
-
-
0028329630
-
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues
-
Zheng CF and Guan KL (1994a) Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues. EMBO Journal 13 1123-1131
-
(1994)
EMBO Journal
, vol.13
, pp. 1123-1131
-
-
Zheng, C.F.1
Guan, K.L.2
-
125
-
-
0028240684
-
Growth factor induced MEK activation is primarily mediated by an activator different from c-raf
-
Zheng C-F, Ohmichi M, Saltiel AR and Guan K-L (1994) Growth factor induced MEK activation is primarily mediated by an activator different from c-raf. Biochemistry 33 5595-5599
-
(1994)
Biochemistry
, vol.33
, pp. 5595-5599
-
-
Zheng, C.-F.1
Ohmichi, M.2
Saltiel, A.R.3
Guan, K.-L.4
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