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Oncogene

Volumn 19, Issue 56, 2000, Pages 6594-6599

Development of anticancer drugs targeting the MAP kinase pathway

(1) Sebolt Leopold, J S a

a PFIZER INC (United States)

Author keywords

Extracellular signal regulated kinase (ERK); MAP kinase kinase (MEK); Mitogen activated protein kinase (MAPK); Raf

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; N [5 (3 DIMETHYLAMINOBENZAMIDO) 2 METHYLPHENYL] 4 HYDROXYBENZAMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; CLINICAL TRIAL; DRUG DESIGN; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; CELL DIVISION; DRUG DELIVERY SYSTEMS; DRUG DESIGN; ENZYME INHIBITORS; FORECASTING; HUMANS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF;

EID: 0034722894 PISSN: 09509232 EISSN: None Source Type: Journal
DOI: 10.1038/sj.onc.1204083 Document Type: Review

Times cited : (306)

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