cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

Cell

Volumn 89, Issue 1, 1997, Pages 73-82

  Vossler, Mark R ^a   Yao, Hong ^a   York, Randall D ^a   Pan, Ming Gui ^a   Rim, Caroline S ^a   Stork, Philip J S ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; NERVE CELL DIFFERENTIATION; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT; TRANSCRIPTION REGULATION;

ANIMALIA; CERVUS ELAPHUS;

EID: 0030963439     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80184-1     Document Type: Article

References (44)

1. raf-1. EMBO J. 13, 1610-1619.
2. Altschuler, D., and Lapetina, E.G. (1993). Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Raf1b. J. Biol. Chem. 268, 7527-7531.
3. Altschuler, D.L., Peterson, S.N., Ostrowski, M.C., and Lapetina, E.G. (1995). Cyclic AMP-dependent activation of Rap1b. J. Biol. Chem. 270, 10373-10376.
4. Barnier, J.V., Papin, C., Eychene, A., Lecoq, O., and Calothy, G. (1995). The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression. J. Biol. Chem. 270, 23381-23389.
5. Burgering, B.M.T., and Bos, J.L. (1995). Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biol. Sci. 20, 18-22.
6. Cook, S.J., and McCormick, F. (1993). Inhibition by cAMP ras-dependent activation of raf. Science 262, 1069-1072.
7. Cook, S.J., Rubinfeld, B., Albert, I., and McCormick, F. (1993). RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts. EMBO J. 12, 3475-3485.
8. Cowley, S., Paterson, H., Kemp, P., and Marshall, C.J. (1994). Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77, 841-852.
9. Dérijard, B., Hibi, M., Wu, I.-H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R.J. (1994). JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
10. Erhardt, P., Troppmair, J., Rapp, U.R., and Cooper, G.M. (1995). Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells. Mol. Cell. Biol. 15, 5524-5530.
11. Faure, M., and Bourne, H.R. (1995). Differential effects of cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass raf-1. Mol. Biol. Cell 6, 1025-1035.
12. Frech, M., John, J., Pizon, V., Chardin, P., Tavitian, A., Clark, R., McCormick, F., and Wittinghofer, A. (1990). Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product. Science 246, 169-171.
13. Frodin, M., Peraldi, P., and Obberghen, E.V. (1994). Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells. J. Biol. Chem. 269, 6207-6214.
14. Gotoh, T., Hattori, S., Nakamura, S., Kitayama, H., Noda, M., Takai, Y., Kaibuchi, K., Matsui, H., Hatase, O., Takahasi, H., et al. (1995). Identification of Rap1 as a target for the Crk SH3 domain - binding guanine nucleotide - releasing factor C3G. Mol. Cell. Biol. 15, 6746-6753.
15. Hallberg, B., Rayter, S.I., and Downward, J. (1994). Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation. J. Biol. Chem. 269, 3913-3916.
16. Hata, Y., Kaibuchi, K., Kawamura, S., Hiroyoshi, M., Shirataki, H., and Takai, Y. (1991). Enhancement of the actions of smg p21 GDP/GTP exchange protein by the protein kinase A - catalyzed phosphorylation of smg p21. J. Biol. Chem. 266, 6571-6577.
17. Heidemann, S.R., Joshi, H.C., Schechter, A., Fletcher, J.R., and Bothwell, M. (1985). Synergistic effects of cyclic AMP and NGF on neurite outgrowth and MT stability of PC12 cells. J. Cell Biol. 100, 916-927.
18. Jaiswal, R.K., Weissinger, E., Kolch, W., and Landreth, G.E. (1996). Nerve growth factor-mediated activation of the mitogen-activated protein (MAP kinase cascade involves a signaling complex containing B-Raf and HSP90). J. Biol. Chem. 271, 23626-23629.
19. Kitayama, H., Matsuzaki, T., Ikawa, Y., and Noda, M. (1990). Genetic analysis of the Krsten-ras-revertant 1 gene: potentiatior of its tumor suppressor activity by specific point mutaions. Proc. Natl. Acad. Sci. USA 87, 4284-4288.
20. Kuroda, S., Ohtsuka, T., Yamamori, B., Fukui, K., Shimizu, K., and Takai, Y. (1996). Different effects of various phospholipids on Kiras-, Ha-ras-, and rap1B-induced B-raf activation. J. Biol. Chem. 271, 14680-14683.
21. Lange-Carter, C.A., Pleiman, C.M., Gardner, A.M., Blumer, K.J., and Johnson, G.L. (1993) A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science 260, 315-319.
22. Leevers, S.J., Paterson, H.F., and Marshall, C.J. (1994). Requirement for ras in raf activation is overcome by targeting raf to the plasma membrane. Nature 369, 411-414.
23. Marais, R., Wynne, J., and Treisman, R. (1993). The SRF accessory protein Elk-1 contains a growth factor - regulated transcriptional activation domain. Cell 73, 381-393.
24. Marshall, C.J. (1995). Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
25. Misra-Press, A., Rim, C.S., Yao, H., Roberson, M.S., and Stork, P.J.S. (1995). A novel mitogen-activated protein kinase phosphatase: structure, expression and regulation. J. Biol. Chem. 270, 14587-14596.
26. Moodie, S.A., Paris, M J., Kolch, W., and Wolfman, A. (1994). Association of MEK1 with p21ras·GMPPNP is dependent on B-Raf. Mol. Cell. Biol. 14, 7153-7162.
27. Nassar, N., Horn, G., Herrmann, C., Block, C., Jankecht, R., and Wittinghofer, A. (1996). Ras/Rap effector specificity determined by charge reversal. Nat. Struct. Biol. 3, 723-729.
28. Ohtsuka, T., Shimizu, K., Yamamori, B., Kuroda, S., and Takai, Y. (1996). Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein. J. Biol. Chem., 271 1258-1261.
29. Okada, Y., Masuda, T., Shinkai, M., Kariya, K., and Kataoka, T. (1996). Post-translational modification of H-ras is required for activation of, but not for association with, B-raf. J. Biol. Chem. 271, 4671-4678.
30. Oshima, M., Sithanadam, G., Rapp, U.R., and Guroff, G. (1991). The phosphorylation and activation of B-raf in PC12 cells stimulated by nerve growth factor. J. Biol. Chem. 266, 23753-23760.
31. Pan, M.-G., Wang, Y.-H., Hirsch, D.D., Labudda, K.,and Stork, P.J.S. (1995). The Wnt-1 proto-oncogene regulates MAP kinase activation by multiple growth factors in PC12 cells. Oncogene 11, 2005-2012.
32. Porfiri, E., and McCormick, F. (1996). Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1. J. Biol. Chem. 271, 5871-5877.
33. Resing, K.A., Mansour, S.J., Hermann, A.S., Johnson, R.S., Candia., J. M., Fukasawa, K., Vande Woude, G.F., and Ahn, N.G. (1995). Determination of v-mos-catalyzed phosphorylation sites and autophosphorylation on MAP kinase kinase by ESI/MS. Biochemistry 34, 2610-2620.
34. Reuter, C.W.M., Catling, A.D., Jelinek, T., and Weber, M.J. (1995). Biochemical analysis of MEK activation in NIH 3T3 fibroblasts. J. Biol. Chem. 270, 7644-7655.
35. 2+/calmodulin-dependent protein kinase, CaM kinase Gr. Proc. Natl. Acad. Sci. USA 88, 2643-2647.
36. Stacy, D.W., Feig, L.A., and Gibbs, J.B. (1991). Dominant inhibitory ras mutants selectively inhibit the activity of either cellular or oncogenic ras. Mol. Cell. Biol. 11, 4053-4064.
37. Urano, T., Emkey, R., and Feig, L.A. (1996) Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation. EMBO J. 15, 810-816.
38. Vaillancourt, R.R., Gardner, A.M., and Johnson, G.L. (1994). B-Raf dependent regulation of the MEK-1/MAP kinase pathway in PC12 cells and regulation by cAMP. Mol. Cell. Biol. 14, 6522-6530.
39. Warne, P.M., Viciana, P.R., and Downward, J. (1993). Direct interaction of ras and the amino-terminal region of raf-1 in vitro. Nature 364, 352-355.
40. Wu, J., Dent, P., Jelinek, T., Wolfman, A., Weber, M.J., and Sturgill, T.W. (1993). Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′, 5′-monophosphate. Science 262, 1065-1068.
41. Yamamori, B., Kuroda, S., Shimizu, K., Fukui, K., Ohtsuka, T., and Takai, Y. (1995). Purification of a ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-raf and 14-3-3 proteins. J. Biol. Chem. 270, 11723-11726.
42. Yao, H., Labudda, K., Rim, C., Capodieci, P., Loda, M., and Stork, P.J.S. (1995). Cyclic adenosine monophosphate can convert epidermal growth factor into a differentiating factor in neuronal cells. J. Biol. Chem. 270, 20748-20753.
43. Yoshida, Y., Kawata, M., Miura, Y., Musha, T., Sasaki, T., Kikuchi, A., and Takai, U. (1992). Microinjection of smg/rap1/Krev-1 p21 into swiss 3T3 cells induces DNA synthesis and morphological changes. Mol. Cell. Biol. 12, 3407-3414.
44. Young, S.W., Dickens, M., and Tavaré, J.M. (1994). Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters. FEBS Lett. 338, 212-216.