Unnatural ligands for engineered proteins: New tools for chemical genetics

Annual Review of Biophysics and Biomolecular Structure

Volumn 29, Issue , 2000, Pages 577-606

  Bishop, Anthony ^a   Buzko, Oleksandr ^a,b   Heyeck Dumas, Stephanie ^a   Jung, Ilyoung ^a,b   Kraybill, Brian ^a,b   Liu, Yi ^a   Shah, Kavita ^a   Ulrich, Scott ^a,b   Witucki, Laurie ^a   Yang, Feng ^a   Zhang, Chao ^a,b   Shokat, Kevan M ^a,b,c  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Orthogonal ligands; Protein design; Protein engineering; Signal transduction

Indexed keywords

MEMBRANE RECEPTOR; NUCLEOTIDE; PROTEIN KINASE;

BINDING SITE; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC ENGINEERING; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; GENETIC TECHNIQUES; GTP PHOSPHOHYDROLASES; HUMANS; KINESIN; LIGANDS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYOSINS; PROTEIN ENGINEERING; PROTEIN KINASES; PROTEINS; SIGNAL TRANSDUCTION;

EID: 0033874150     PISSN: 10568700     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biophys.29.1.577     Document Type: Review

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