-
1
-
-
0000951677
-
Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acids
-
Geysen, H. M., Meloen, R. H., and Barteling, S. J. (1984) Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acids. Proc. Natl. Acad. Sci. USA 81, 3998-4002.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 3998-4002
-
-
Geysen, H.M.1
Meloen, R.H.2
Barteling, S.J.3
-
2
-
-
85047670016
-
Rapid optimization of organic reactions on solid phase using the multipin approach: Synthesis of 4-aminoproline analogues by reductive amination
-
Bray, A. M., Chiefari, D. S., Valerio, R. M., and Maeji, N. J. (1995) Rapid optimization of organic reactions on solid phase using the multipin approach: synthesis of 4-aminoproline analogues by reductive amination. Tetrahedron Lett. 36, 5081-5084.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 5081-5084
-
-
Bray, A.M.1
Chiefari, D.S.2
Valerio, R.M.3
Maeji, N.J.4
-
3
-
-
0026419319
-
Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery
-
Houghten, R. A., Pinilla, C., Blondelle, S. E., Appel, J. R., Dooley, C. T., and Cuervo, J. H. (1991) Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature 354, 84-86.
-
(1991)
Nature
, vol.354
, pp. 84-86
-
-
Houghten, R.A.1
Pinilla, C.2
Blondelle, S.E.3
Appel, J.R.4
Dooley, C.T.5
Cuervo, J.H.6
-
4
-
-
0000478940
-
General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids
-
Houghten, R. A. (1985) General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc. Natl. Acad. Sci. USA 82, 5131-5135.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 5131-5135
-
-
Houghten, R.A.1
-
5
-
-
0025893762
-
General method for rapid synthesis of multi-component peptides mixtures
-
Furka, A., Sebestyen, F., Asgedom, M., and Dibo, G. (1991) General method for rapid synthesis of multi-component peptides mixtures. Int. J. Pep. Prot. Res. 37, 487-493.
-
(1991)
Int. J. Pep. Prot. Res.
, vol.37
, pp. 487-493
-
-
Furka, A.1
Sebestyen, F.2
Asgedom, M.3
Dibo, G.4
-
6
-
-
0001939276
-
Cornucopia of peptides by synthesis
-
Prague, Poster-47
-
Furka, A., Sebestyen, F., Asgedom, M., and Dibo, G. (1988) Cornucopia of peptides by synthesis. Abst. 14th. Intl. Congress of Biochemistry, Prague, Poster-47.
-
(1988)
Abst. 14th. Intl. Congress of Biochemistry
-
-
Furka, A.1
Sebestyen, F.2
Asgedom, M.3
Dibo, G.4
-
7
-
-
0026419328
-
A new type of synthetic library for identifying ligand binding activity
-
Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierski, W. M., and Knapp, R. J. (1991) A new type of synthetic library for identifying ligand binding activity. Nature 354, 82-84.
-
(1991)
Nature
, vol.354
, pp. 82-84
-
-
Lam, K.S.1
Salmon, S.E.2
Hersh, E.M.3
Hruby, V.J.4
Kazmierski, W.M.5
Knapp, R.J.6
-
8
-
-
0004041609
-
Combinatorial chemistry
-
Abelson, J. N. (ed.) (1996) Combinatorial chemistry. Methods Enzymol. 267,
-
(1996)
Methods Enzymol.
, vol.267
-
-
Abelson, J.N.1
-
9
-
-
0030253986
-
Selection of proteins and peptides from libraries displayed on filamentous bacteriophage
-
McGregor, D. (1996) Selection of proteins and peptides from libraries displayed on filamentous bacteriophage. Mol. Biotechnol. 6, 155-162.
-
(1996)
Mol. Biotechnol.
, vol.6
, pp. 155-162
-
-
McGregor, D.1
-
10
-
-
0029942897
-
Generation and use of non-support-bound peptide and peptidomimetic combinatorial libraries
-
Ostresh, J. M., Blondelle, S. E., Dorner, B., and Houghten, R. A. (1996) Generation and use of non-support-bound peptide and peptidomimetic combinatorial libraries. Methods Enzymol. 267, 220-234.
-
(1996)
Methods Enzymol.
, vol.267
, pp. 220-234
-
-
Ostresh, J.M.1
Blondelle, S.E.2
Dorner, B.3
Houghten, R.A.4
-
11
-
-
0030021761
-
Novel antimicrobial compounds identified using synthetic combinatorial library technology
-
Blondelle, S. E. and Houghten, R. A. (1996) Novel antimicrobial compounds identified using synthetic combinatorial library technology. Trends Biotechnol. 14, 60-65.
-
(1996)
Trends Biotechnol.
, vol.14
, pp. 60-65
-
-
Blondelle, S.E.1
Houghten, R.A.2
-
12
-
-
0029867221
-
Synthetic combinatorial libraries: Novel discovery strategy for identification of antimicrobial agents
-
Blondelle, S. E., Perea-Paya, and Houghton, R. A. (1996) Synthetic combinatorial libraries: novel discovery strategy for identification of antimicrobial agents. Antimicrob. Agents Chemother. 40, 1067-1071.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 1067-1071
-
-
Blondelle, S.E.1
Perea-Paya2
Houghton, R.A.3
-
13
-
-
0031012062
-
Display of heterologous proteins on the surface of microorganisms from the screening of combinatorial libraries to live recombinant vaccines
-
Georgiou, G., Stathopoulos, C., Daugherty, P. S., Nayak, A. R., Iverson, B. L., and Curtiss, R. (1997) Display of heterologous proteins on the surface of microorganisms from the screening of combinatorial libraries to live recombinant vaccines. Nature Biotechnol. 15, 29-34.
-
(1997)
Nature Biotechnol.
, vol.15
, pp. 29-34
-
-
Georgiou, G.1
Stathopoulos, C.2
Daugherty, P.S.3
Nayak, A.R.4
Iverson, B.L.5
Curtiss, R.6
-
14
-
-
0030072583
-
Structural aspect of antibody-antigen interaction revealed through small random peptide libraries
-
Slootstra, J. W., Puijk, W. C., Ligtvoet, G. J., Langeveld, J. P. M., and Meloen, R. H. (1996) Structural aspect of antibody-antigen interaction revealed through small random peptide libraries. Mol. Diversity 1, 87-96.
-
(1996)
Mol. Diversity
, vol.1
, pp. 87-96
-
-
Slootstra, J.W.1
Puijk, W.C.2
Ligtvoet, G.J.3
Langeveld, J.P.M.4
Meloen, R.H.5
-
15
-
-
0029826155
-
Linear epitopes of sperm whale myoglobin identified by polyclonal antibody screening of random peptide library
-
Yao, Z. J., Chan, M. C., Kao, M. C. C., and Chang, M. C. M. (1996) Linear epitopes of sperm whale myoglobin identified by polyclonal antibody screening of random peptide library. Int. Pept. Protein Res. 48, 477-485.
-
(1996)
Int. Pept. Protein Res.
, vol.48
, pp. 477-485
-
-
Yao, Z.J.1
Chan, M.C.2
Kao, M.C.C.3
Chang, M.C.M.4
-
16
-
-
0026900384
-
Use of the multipin peptide synthesis technique for the generation of antipeptide sera
-
Triantufyllou, B., Tribbick, G., Maeji, N. J., and Geysen, H. M. (1993) Use of the multipin peptide synthesis technique for the generation of antipeptide sera. Cell Biophys. 21, 33-52.
-
(1993)
Cell Biophys.
, vol.21
, pp. 33-52
-
-
Triantufyllou, B.1
Tribbick, G.2
Maeji, N.J.3
Geysen, H.M.4
-
17
-
-
0028960023
-
The use of light directed combinatorial peptide synthesis in epitope mapping
-
Homes, C. P., Adams, C. L., Kochersperger, L. M., Mortensen, R. B., and Aldwin, L. A. (1995) The use of light directed combinatorial peptide synthesis in epitope mapping. Biopolymers (Peptide Sci.) 37, 199-211.
-
(1995)
Biopolymers (Peptide Sci.)
, vol.37
, pp. 199-211
-
-
Homes, C.P.1
Adams, C.L.2
Kochersperger, L.M.3
Mortensen, R.B.4
Aldwin, L.A.5
-
18
-
-
0028857925
-
A mimeotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response
-
Steward, M. W., Stanley, C. M., and Obeidi, O. E. (1995) A mimeotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response. J. Virol. 69, 7668-7673.
-
(1995)
J. Virol.
, vol.69
, pp. 7668-7673
-
-
Steward, M.W.1
Stanley, C.M.2
Obeidi, O.E.3
-
19
-
-
0029044977
-
A general route to fingerprint analysis of peptide-antibody interaclions using a clustered amino acid peptide library: Comparison with phage display library
-
Kramer, A., Vakalopoulou, E., Schleuning, W.-D., and Schneider-Mergener, J. (1995) A general route to fingerprint analysis of peptide-antibody interaclions using a clustered amino acid peptide library: comparison with phage display library. Mol. Immunol. 32, 459-465.
-
(1995)
Mol. Immunol.
, vol.32
, pp. 459-465
-
-
Kramer, A.1
Vakalopoulou, E.2
Schleuning, W.-D.3
Schneider-Mergener, J.4
-
20
-
-
0343150927
-
Determination of T cell epitopes with random peptide libraries
-
Gundlach, B. R., Wiesmuller, K-H., Junt, T., Kienle, S., Jung, G., and Waldlen, P. (1996) Determination of T cell epitopes with random peptide libraries. J. Immunol. Methods 192, 149-155.
-
(1996)
J. Immunol. Methods
, vol.192
, pp. 149-155
-
-
Gundlach, B.R.1
Wiesmuller, K.-H.2
Junt, T.3
Kienle, S.4
Jung, G.5
Waldlen, P.6
-
21
-
-
0029798722
-
New ligands binding to the human leukocyte antigen class II molecule DRB1 super *0101 based on the activity pattern of an undecapeptide library
-
Fleckenstein, B., Kalbacher, H., Muller, C. P., Stoll, D., Halder, T., Jung, G., and Wiesmuller, K.-H. (1996) New ligands binding to the human leukocyte antigen class II molecule DRB1 super *0101 based on the activity pattern of an undecapeptide library. Eur. J. Biochem. 240, 71-77.
-
(1996)
Eur. J. Biochem.
, vol.240
, pp. 71-77
-
-
Fleckenstein, B.1
Kalbacher, H.2
Muller, C.P.3
Stoll, D.4
Halder, T.5
Jung, G.6
Wiesmuller, K.-H.7
-
22
-
-
0027052983
-
Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries
-
Pinilla, C., Appel, J. R., Blane, P., and Houghten, R. A. (1992) Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries. Biochemistry 13, 901-905.
-
(1992)
Biochemistry
, vol.13
, pp. 901-905
-
-
Pinilla, C.1
Appel, J.R.2
Blane, P.3
Houghten, R.A.4
-
23
-
-
0030228115
-
Identification of peptides mimicking the antigenicity and immunogenicity of conformational epitopes on Japanese encephalitis virus protein using synthetic peptide libraries
-
Hirabayashi, Y., Fukuda, H., Kimura, J., Miyamoto, M., and Yasui, K. (1996) Identification of peptides mimicking the antigenicity and immunogenicity of conformational epitopes on Japanese encephalitis virus protein using synthetic peptide libraries. J. Virol. Methods 61, 23-36.
-
(1996)
J. Virol. Methods
, vol.61
, pp. 23-36
-
-
Hirabayashi, Y.1
Fukuda, H.2
Kimura, J.3
Miyamoto, M.4
Yasui, K.5
-
24
-
-
0029927206
-
Sculpted immunogens; B-Cell epitope optimization using constrained secondary structure libraries
-
Urban, J., Qabar, M., Sia, C., Klein, M., and Kahn, M. (1996) Sculpted immunogens; B-Cell epitope optimization using constrained secondary structure libraries. Bioorg. Med. Chem. 4, 673-676.
-
(1996)
Bioorg. Med. Chem.
, vol.4
, pp. 673-676
-
-
Urban, J.1
Qabar, M.2
Sia, C.3
Klein, M.4
Kahn, M.5
-
25
-
-
0030175952
-
Novel bradykinin receptor antagonists from a structurally directed non-peptide combinatorial library
-
Chakravarti, B. J., Mavunkel, R. R., Goehring, and Kyle D. J. (1996) Novel bradykinin receptor antagonists from a structurally directed non-peptide combinatorial library. Immunopharmacology 35, 61-67.
-
(1996)
Immunopharmacology
, vol.35
, pp. 61-67
-
-
Chakravarti, B.J.1
Mavunkel, R.R.2
Goehring3
Kyle, D.J.4
-
26
-
-
0029837395
-
Rediscovery an endothelin antagonist (BQ-123): A self-deconvoluting cyclic pentapeptide library
-
Spatola, A. F., Crozet, Y., de Wit, D., and Yanagisawa, M. (1996) Rediscovery an endothelin antagonist (BQ-123): a self-deconvoluting cyclic pentapeptide library. J. Med. Chem. 39, 3842-3846.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 3842-3846
-
-
Spatola, A.F.1
Crozet, Y.2
De Wit, D.3
Yanagisawa, M.4
-
27
-
-
0026593030
-
A receptor
-
A receptor. Life Sci. 50, 2447-2455.
-
(1992)
Life Sci.
, vol.50
, pp. 2447-2455
-
-
Ihara, M.1
Noguchi, K.2
Saeki, T.3
Fukuroda, T.4
Tsuchida, S.5
Kimura, S.6
Fukami, T.7
Ishikawa, K.8
Nishikibe, M.9
Yano, M.10
-
28
-
-
0030598195
-
Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042
-
Hoekstra, W. J., Maryanoff, B. E., Andrade-Gordon, P., Cohen, J. H., Costanzo, M. J., Damiano, B. P., Haertlein, B. J., Harris, B. D., Kauffman, J. A., Keane, P. M., McComsey, D. F., Villani, Jr., F. J., and Yabut, S. C. (1996) Solid-phase parallel synthesis applied to lead optimization: discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042. Bioorg. Med. Chem. Lett. 6, 2372-2376.
-
(1996)
Bioorg. Med. Chem. Lett.
, vol.6
, pp. 2372-2376
-
-
Hoekstra, W.J.1
Maryanoff, B.E.2
Andrade-Gordon, P.3
Cohen, J.H.4
Costanzo, M.J.5
Damiano, B.P.6
Haertlein, B.J.7
Harris, B.D.8
Kauffman, J.A.9
Keane, P.M.10
McComsey, D.F.11
Villani Jr., F.J.12
Yabut, S.C.13
-
29
-
-
0031031681
-
Development of the new potent non-peptide GpIIb/IIIa antagonist NSL-95301 by utilizing combinatorial technique
-
Harada, T., Katada, J., Tachiki, A., Asari, T., Iijima, K., Uno, I., Ojima, I., and Hayashi, Y. (1996) Development of the new potent non-peptide GpIIb/IIIa antagonist NSL-95301 by utilizing combinatorial technique. Bioorg. Med. Chem. Lett. 7, 209-212.
-
(1996)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 209-212
-
-
Harada, T.1
Katada, J.2
Tachiki, A.3
Asari, T.4
Iijima, K.5
Uno, I.6
Ojima, I.7
Hayashi, Y.8
-
30
-
-
0027934780
-
Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library
-
Zuckermann, R. N., Martin, E. J., Spellmeyer, D. C., Stauber, G. B., Shoemaker, K. R., Kerr, J. M., Figliozzi, G. M., Goff, D. A., Siani, M. A., Simon, R. J., Banville, S. C., Brown, E. G., Wang, L., Richter, L. S., and Moos, W. H. (1994) Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library. J. Med. Chem. 37, 2678-2685.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 2678-2685
-
-
Zuckermann, R.N.1
Martin, E.J.2
Spellmeyer, D.C.3
Stauber, G.B.4
Shoemaker, K.R.5
Kerr, J.M.6
Figliozzi, G.M.7
Goff, D.A.8
Siani, M.A.9
Simon, R.J.10
Banville, S.C.11
Brown, E.G.12
Wang, L.13
Richter, L.S.14
Moos, W.H.15
-
31
-
-
15844410706
-
Screening derivatized peptide libraries for light binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry
-
Gao, J., Cheng, X., Chen, R., Sigal, G. B., Bruce, J. E., Schwartz, B. L., Hofstadler, S. A., Anderson, G. A., Smith, R. D., and Whitesides, G. M. (1996) Screening derivatized peptide libraries for light binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry. J. Med. Chem. 39, 1949-1955.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1949-1955
-
-
Gao, J.1
Cheng, X.2
Chen, R.3
Sigal, G.B.4
Bruce, J.E.5
Schwartz, B.L.6
Hofstadler, S.A.7
Anderson, G.A.8
Smith, R.D.9
Whitesides, G.M.10
-
32
-
-
0029741201
-
Development of the first potent and selective inhibitor of the zinc endopeptidase neurolysin using a systematic approach based on combinatorial chemistry of phosphinic peptides
-
Jiracek, J., Yiotakis, A., Vincenti, B., Checler, F., and Dive, V. (1996) Development of the first potent and selective inhibitor of the zinc endopeptidase neurolysin using a systematic approach based on combinatorial chemistry of phosphinic peptides. J. Biol. Chem. 271, 19,606-19,611.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19606-19611
-
-
Jiracek, J.1
Yiotakis, A.2
Vincenti, B.3
Checler, F.4
Dive, V.5
-
33
-
-
0029076548
-
A transition state analogue inhibitor combinatorial library
-
Campbell, D. A., Bermak, J. C., Burkoth, T. S., and Patel, D. V. (1995) A transition state analogue inhibitor combinatorial library. J. Am. Chem. Soc. 117, 5381-5382
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 5381-5382
-
-
Campbell, D.A.1
Bermak, J.C.2
Burkoth, T.S.3
Patel, D.V.4
-
34
-
-
77957154728
-
Thrombin and Factor Xa inhibition
-
Edmunds, J. J., Rapundalo, S. T., and Siddiqui, A. A. (1996) Thrombin and Factor Xa inhibition. Ann. Rep. Med. Chem. 31, 51-90.
-
(1996)
Ann. Rep. Med. Chem.
, vol.31
, pp. 51-90
-
-
Edmunds, J.J.1
Rapundalo, S.T.2
Siddiqui, A.A.3
-
35
-
-
0028279903
-
A comparative study of prothrombinase and thrombin inhibitors in a novel rabbit model of non-occlusive deep vein thrombosis
-
Hollenbach, S., Sinha, U., Lin, P.-H., Needham, K., Frey, L., Hancock, T., Wong, A., and Wolf, D. (1994) A comparative study of prothrombinase and thrombin inhibitors in a novel rabbit model of non-occlusive deep vein thrombosis. Thromb. Haemost. 71, 357-362.
-
(1994)
Thromb. Haemost.
, vol.71
, pp. 357-362
-
-
Hollenbach, S.1
Sinha, U.2
Lin, P.-H.3
Needham, K.4
Frey, L.5
Hancock, T.6
Wong, A.7
Wolf, D.8
-
36
-
-
0032570258
-
-
Ostrem, J. A., Al-Obeidi, F. A., Safar, P., Safarova, A., Stringer, S., Patek, M., Cross, M. T., Spoonamore, J., LoCascio, J. C., Kasireddy, P., Thorpe, D., Sepetov, N., Lebl, M., Wildgoose, P., and Strop, P. (1998) Biochem. 37, 1053-1059.
-
(1998)
Biochem.
, vol.37
, pp. 1053-1059
-
-
Ostrem, J.A.1
Al-Obeidi, F.A.2
Safar, P.3
Safarova, A.4
Stringer, S.5
Patek, M.6
Cross, M.T.7
Spoonamore, J.8
LoCascio, J.C.9
Kasireddy, P.10
Thorpe, D.11
Sepetov, N.12
Lebl, M.13
Wildgoose, P.14
Strop, P.15
-
37
-
-
0029126779
-
Inhibitors of human heart chymase based on a peptide library
-
Bastos, M., Maeji, N. T., and Abeles, R. H. (1995) Inhibitors of human heart chymase based on a peptide library. Proc. Natl. Acad. Sci. USA 92, 6738-6742.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6738-6742
-
-
Bastos, M.1
Maeji, N.T.2
Abeles, R.H.3
-
38
-
-
0038089976
-
Selection of chymotrypsin inhibitors from a conformationally-constrained combinatorial peptide library
-
McBride, J. D., Freeman, N., Domingo, G. J., and Leatherbarrow, M. (1996) Selection of chymotrypsin inhibitors from a conformationally-constrained combinatorial peptide library. J. Mol. Biol. 259, 819-827.
-
(1996)
J. Mol. Biol.
, vol.259
, pp. 819-827
-
-
McBride, J.D.1
Freeman, N.2
Domingo, G.J.3
Leatherbarrow, M.4
-
39
-
-
15444343761
-
Screening of synthetic peptide library against glycosomal phosphoglycerate kinase of Trypanosoma brucei
-
Samson, I., van Aerschut, A., Samyn, B., van Beeumen, J., and Herdewijn, P. (1995) Screening of synthetic peptide library against glycosomal phosphoglycerate kinase of Trypanosoma brucei. Lett. Peptide Sci. 2, 217-219.
-
(1995)
Lett. Peptide Sci.
, vol.2
, pp. 217-219
-
-
Samson, I.1
Van Aerschut, A.2
Samyn, B.3
Van Beeumen, J.4
Herdewijn, P.5
-
40
-
-
15444348069
-
Screening of a synthetic pentapeptide library composed of D-amino acids against fructose-1,6-bisphosphate aldolase
-
Samson, I., Rozenski, J., Aerschot, A. van, Samyn, B., van Beeumen, J., and Herdewijn, P. (1995) Screening of a synthetic pentapeptide library composed of D-amino acids against fructose-1,6-bisphosphate aldolase. Lett. Peptide Sci. 2, 259,260.
-
(1995)
Lett. Peptide Sci.
, vol.2
, pp. 259
-
-
Samson, I.1
Rozenski, J.2
Aerschot, A.3
Van Samyn, B.4
Van Beeumen, J.5
Herdewijn, P.6
-
41
-
-
0026345157
-
The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures
-
Owens, R. A., Gesellchen, P. D., Houchins, B. J., and DiMarchi, R. D. (1991) The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures. Biochem. Biophys. Res. Comm. 181, 402-408.
-
(1991)
Biochem. Biophys. Res. Comm.
, vol.181
, pp. 402-408
-
-
Owens, R.A.1
Gesellchen, P.D.2
Houchins, B.J.3
Dimarchi, R.D.4
-
42
-
-
0029855561
-
Complementarity of combinatorial chemistry and structure-based ligand design: Application to the discovery of novel inhibitors of matrix metalloproteinases
-
Rockwell, A., Melden, M., Cepeland, R. A., Hardman, K., Decicco, C. P., and DeGrado, W. F. (1996) Complementarity of combinatorial chemistry and structure-based ligand design: Application to the discovery of novel inhibitors of matrix metalloproteinases. J. Amer. Chem. Soc. 118, 10,337-10,338.
-
(1996)
J. Amer. Chem. Soc.
, vol.118
, pp. 10337-10338
-
-
Rockwell, A.1
Melden, M.2
Cepeland, R.A.3
Hardman, K.4
Decicco, C.P.5
Degrado, W.F.6
-
43
-
-
0342318652
-
Rapid identification of phosphopeptide ligands for SH2 domains
-
Muller, K., Gombert, F. O., Manning, U., Grossmuller, F., Graff, P., Zaege, H., Zuber, J. F., Freuler, F., Tschopp, C., and Baumannm, G. (1996) Rapid identification of phosphopeptide ligands for SH2 domains. J. Biol. Chem. 271, 16,500-16,505.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16500-16505
-
-
Muller, K.1
Gombert, F.O.2
Manning, U.3
Grossmuller, F.4
Graff, P.5
Zaege, H.6
Zuber, J.F.7
Freuler, F.8
Tschopp, C.9
Baumannm, G.10
-
44
-
-
0030054916
-
Specificity of Lim domain interactions with receptor tyrosine kinases
-
Wu, R., Durick, K., Songyang, Z., Cantley, L. C., Taylor, S. S., and Gill, G. N. (1996) Specificity of Lim domain interactions with receptor tyrosine kinases. J. Biol. Chem. 271, 15,934-15,941.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15934-15941
-
-
Wu, R.1
Durick, K.2
Songyang, Z.3
Cantley, L.C.4
Taylor, S.S.5
Gill, G.N.6
-
45
-
-
0029010308
-
The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif
-
Songyang, Z., Margolis, B., Chaudhuri, M., Shoelson, S. E., and Cantley, L. C. (1995) The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif. J. Biol. Chem. 270, 14,863-14,866.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14863-14866
-
-
Songyang, Z.1
Margolis, B.2
Chaudhuri, M.3
Shoelson, S.E.4
Cantley, L.C.5
-
46
-
-
0029559786
-
The specificity of the transforming growth factor b receptor kinases determined by a spatially addressable peptide library
-
Luo, K., Zhou, P., and Lodish, H. F. (1995) The specificity of the transforming growth factor b receptor kinases determined by a spatially addressable peptide library. Proc. Natl. Acad. Sci. USA 92, 11,761-11,765.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11761-11765
-
-
Luo, K.1
Zhou, P.2
Lodish, H.F.3
-
47
-
-
0343177223
-
A structural basis for substrate specificities of protein Scr/Thr kinases: Primary sequence preference of Casein kinases I and II, NIMA, Phosphorylase kinase, Calmodulin-dependent kinase II, CDK5, and Erk1
-
Songyang, Z., Lu, K. P., Kwon, Y. T., Tsal, L.-H., Filhol, O., Cochet, C., Brickey, D. A., Soderling, T. R., Bartleson, C., Graves, D. J., DeMaggio, A. J., Hoekstra, M. F., Blenis, J., Hunter, T., and Cantley, L. C. (1996) A structural basis for substrate specificities of protein Scr/Thr kinases: primary sequence preference of Casein kinases I and II, NIMA, Phosphorylase kinase, Calmodulin-dependent kinase II, CDK5, and Erk1. Mol. Cell. Biol. 16, 6486-6493.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6486-6493
-
-
Songyang, Z.1
Lu, K.P.2
Kwon, Y.T.3
Tsal, L.-H.4
Filhol, O.5
Cochet, C.6
Brickey, D.A.7
Soderling, T.R.8
Bartleson, C.9
Graves, D.J.10
DeMaggio, A.J.11
Hoekstra, M.F.12
Blenis, J.13
Hunter, T.14
Cantley, L.C.15
-
48
-
-
0030607176
-
Amino-terminal sequence determinants for substrate recognition by platelet-derived growth factor receptor tyrosine kinase
-
Chan, P. M., Keller, P. R., Connors, R. W., Leopold, W. R., and Miller, W. T. (1996) Amino-terminal sequence determinants for substrate recognition by platelet-derived growth factor receptor tyrosine kinase. FEBS Lett. 394, 121-125.
-
(1996)
FEBS Lett.
, vol.394
, pp. 121-125
-
-
Chan, P.M.1
Keller, P.R.2
Connors, R.W.3
Leopold, W.R.4
Miller, W.T.5
-
49
-
-
0028938721
-
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
-
Songyang, Z., Carraway III, K. L., Eck, M. J., Harrison, S. C., Feldman, R. A., Mohammadi, M., Schlessinger, J., Hubbard, S. R., Smith, D. P., Eng, C., Lorenzo, M. J., Ponder, B. A. T., Mayer, B. J., and Cantley, L. C. (1995) Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature 373, 536-539.
-
(1995)
Nature
, vol.373
, pp. 536-539
-
-
Songyang, Z.1
Carraway III, K.L.2
Eck, M.J.3
Harrison, S.C.4
Feldman, R.A.5
Mohammadi, M.6
Schlessinger, J.7
Hubbard, S.R.8
Smith, D.P.9
Eng, C.10
Lorenzo, M.J.11
Ponder, B.A.T.12
Mayer, B.J.13
Cantley, L.C.14
-
50
-
-
0029911731
-
The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor
-
Pandit, S. D., Donis-Keller, H., Iwamoto, T., Tomich, J. M., and Pike, L. J. (1996) The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor. J. Biol. Chem. 271, 5850-5858.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5850-5858
-
-
Pandit, S.D.1
Donis-Keller, H.2
Iwamoto, T.3
Tomich, J.M.4
Pike, L.J.5
-
51
-
-
0029046713
-
Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases
-
Lam, K. S., Wu, J., and Lou, Q. (1995) Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases. Int. J. Peptide Protein Res. 45, 587-592.
-
(1995)
Int. J. Peptide Protein Res.
, vol.45
, pp. 587-592
-
-
Lam, K.S.1
Wu, J.2
Lou, Q.3
-
52
-
-
10544220839
-
Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library
-
Wallace, A., Koblan, K. S., Hamilton, K., Marquis-Omer, D. J., Miller, P. J., Mosser, S. D., Omer, C. A., Schaber, M. D., Cortese, R., Oliff, A., Gibbs, J. B., and Pessi, A. (1996) Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library. J. Biol. Chem. 271, 31,306-31,311.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31306-31311
-
-
Wallace, A.1
Koblan, K.S.2
Hamilton, K.3
Marquis-Omer, D.J.4
Miller, P.J.5
Mosser, S.D.6
Omer, C.A.7
Schaber, M.D.8
Cortese, R.9
Oliff, A.10
Gibbs, J.B.11
Pessi, A.12
-
53
-
-
34548199680
-
Discovery of nanomolar ligands for 7-transmembrane G protein-coupled receptors from a diverse N-(substituted)glycine peptoid library
-
Zuckermann, R. N., Martin, E. J., Spellmeyer, D. C., Stauber, G. B., Shoemaker, K. R., Kerr, J. M., Figliozzi, G. M., Goff, D. A., Siani, M. A., Simon, R. J., Bunville, S. C., Brown, E. G., Wang, L., Richter, L. S., and Moos, W. H. (1995) Discovery of nanomolar ligands for 7-transmembrane G protein-coupled receptors from a diverse N-(substituted)glycine peptoid library. Chemtracts (Org. Chem.) 8, 36-40.
-
(1995)
Chemtracts (Org. Chem.)
, vol.8
, pp. 36-40
-
-
Zuckermann, R.N.1
Martin, E.J.2
Spellmeyer, D.C.3
Stauber, G.B.4
Shoemaker, K.R.5
Kerr, J.M.6
Figliozzi, G.M.7
Goff, D.A.8
Siani, M.A.9
Simon, R.J.10
Bunville, S.C.11
Brown, E.G.12
Wang, L.13
Richter, L.S.14
Moos, W.H.15
-
54
-
-
0030884435
-
Design of peptides, proteins, and peptidomimetics in chi space
-
Hruby, V. J., Li, G., Haskell-Luevano, C., and Shenderovich, M. (1997) Design of peptides, proteins, and peptidomimetics in chi space. Peptide Sci. (Biopolymers), 43, 219-266.
-
(1997)
Peptide Sci. (Biopolymers)
, vol.43
, pp. 219-266
-
-
Hruby, V.J.1
Li, G.2
Haskell-Luevano, C.3
Shenderovich, M.4
-
55
-
-
0029841811
-
Affinity capillary electrophoresis-mass spectrometry for screening combinatorial libraries
-
Chu, Y.-H., Dunayevskiy, Y. M., Kirby, D. P., Vouros, P., and Karger, B. L. (1996) Affinity capillary electrophoresis-mass spectrometry for screening combinatorial libraries. J. Amer. Chem. Soc. 118, 7827-7835.
-
(1996)
J. Amer. Chem. Soc.
, vol.118
, pp. 7827-7835
-
-
Chu, Y.-H.1
Dunayevskiy, Y.M.2
Kirby, D.P.3
Vouros, P.4
Karger, B.L.5
-
56
-
-
0029109272
-
Combinatorial synthesis and multidimensional NMR spectroscopy: An approach to understanding protein-ligand interaction
-
Chen, J. K. and Schreiber, S. L. (1995) Combinatorial synthesis and multidimensional NMR spectroscopy: An approach to understanding protein-ligand interaction. Angew. Chemie Int. Ed. Engl. 34, 935-969.
-
(1995)
Angew. Chemie Int. Ed. Engl.
, vol.34
, pp. 935-969
-
-
Chen, J.K.1
Schreiber, S.L.2
-
57
-
-
0030056289
-
Combinatorial peptide libraries: Robotic synthesis and analysis by nuclear magnetic resonance, mass spectrometry, tandem mass spectrometry and high performance capillary electrophoresis techniques
-
Boutin, J. A., Henning, P., Lambert, D.-H., Bertin, S., Petit, L., Mahieu, J.-P., Serkiz, B., Volland, J.-P., and Fauchere, J.-L. (1996) Combinatorial peptide libraries: Robotic synthesis and analysis by nuclear magnetic resonance, mass spectrometry, tandem mass spectrometry and high performance capillary electrophoresis techniques. Analyt. Biochem. 234, 126-141.
-
(1996)
Analyt. Biochem.
, vol.234
, pp. 126-141
-
-
Boutin, J.A.1
Henning, P.2
Lambert, D.-H.3
Bertin, S.4
Petit, L.5
Mahieu, J.-P.6
Serkiz, B.7
Volland, J.-P.8
Fauchere, J.-L.9
-
58
-
-
0002434704
-
Peptidomimetic and nonpeptide drug discovery: Impact of structure-based drug design
-
(Veerapandian, P., ed.), Marcel Dekker, NY
-
Sawyer, T. K. (1997) Peptidomimetic and nonpeptide drug discovery: Impact of structure-based drug design, in Structure-Based Drug Design: Diseases, Targets, Techniques and Developments, vol. I (Veerapandian, P., ed.), Marcel Dekker, NY, pp. 559-634.
-
(1997)
Structure-Based Drug Design: Diseases, Targets, Techniques and Developments
, vol.1
, pp. 559-634
-
-
Sawyer, T.K.1
-
59
-
-
0030274647
-
Genomic sciences and the medicines of tomorrow
-
Drews, J. (1996) Genomic sciences and the medicines of tomorrow. Nature Biotechnol. 14, 1516,1517.
-
(1996)
Nature Biotechnol.
, vol.14
, pp. 1516
-
-
Drews, J.1
|