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Volumn 22, Issue 3-4, 2003, Pages 283-319

Monitoring immune responses in cancer patients receiving tumor vaccines

Author keywords

Cancer vaccines; Immunomonitoring assays

Indexed keywords

CANCER VACCINE; CYTOKINE;

EID: 0038274637     PISSN: 08830185     EISSN: None     Source Type: Journal    
DOI: 10.1080/08830180305226     Document Type: Review
Times cited : (27)

References (135)
  • 2
    • 0035425422 scopus 로고    scopus 로고
    • Designer dendritic cells for tolerance induction: Guided not misguided missiles
    • H. Hackstein, A.E. Morelli, and A.W. Thomson, Designer dendritic cells for tolerance induction: Guided not misguided missiles. Trends Immunol., 22(8): 437-442, 2001.
    • (2001) Trends Immunol. , vol.22 , Issue.8 , pp. 437-442
    • Hackstein, H.1    Morelli, A.E.2    Thomson, A.W.3
  • 3
    • 0034919344 scopus 로고    scopus 로고
    • Dendritic cells as a tool to induce anergic and regulatory T cells
    • H. Jonuleit, E. Schmitt, K. Steinbrink, and A.H. Enk, Dendritic cells as a tool to induce anergic and regulatory T cells. Trends Immunol., 22(7): 394-400, 2001.
    • (2001) Trends Immunol. , vol.22 , Issue.7 , pp. 394-400
    • Jonuleit, H.1    Schmitt, E.2    Steinbrink, K.3    Enk, A.H.4
  • 4
    • 0034923333 scopus 로고    scopus 로고
    • Modulating the immune response with dendritic cells and their growth factors
    • B. Pulendran, J. Banchereau, E. Maraskovsky, and C. Maliszewski, Modulating the immune response with dendritic cells and their growth factors. Trends Immunol., 22(1): 41-47, 2001.
    • (2001) Trends Immunol. , vol.22 , Issue.1 , pp. 41-47
    • Pulendran, B.1    Banchereau, J.2    Maraskovsky, E.3    Maliszewski, C.4
  • 6
    • 0035102242 scopus 로고    scopus 로고
    • Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
    • T.A. Waldmann, S. Dubois, and Y. Tagaya, Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy. Immunity, 14(2): 105-110, 2001.
    • (2001) Immunity , vol.14 , Issue.2 , pp. 105-110
    • Waldmann, T.A.1    Dubois, S.2    Tagaya, Y.3
  • 8
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • I.S. Grewal, and R.A. Flavell, CD40 and CD154 in cell-mediated immunity. Ann. Rev. Immunol., 16: 111-135, 1998.
    • (1998) Ann. Rev. Immunol. , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 9
    • 0032394030 scopus 로고    scopus 로고
    • OX-40: Life beyond the effector T cell stage
    • A.D. Weinberg, A.T. Vella, and M. Croft, OX-40: Life beyond the effector T cell stage. Semin. Immunol., 10(6): 471-480, 1998.
    • (1998) Semin. Immunol. , vol.10 , Issue.6 , pp. 471-480
    • Weinberg, A.D.1    Vella, A.T.2    Croft, M.3
  • 10
    • 0034921235 scopus 로고    scopus 로고
    • The expanding world of co-stimulation: The two-signal model revisited
    • C.A. Chambers, The expanding world of co-stimulation: The two-signal model revisited. Trends Immunol., 22(4): 217-223, 2001.
    • (2001) Trends Immunol. , vol.22 , Issue.4 , pp. 217-223
    • Chambers, C.A.1
  • 11
    • 0030272703 scopus 로고    scopus 로고
    • Is cancer dangerous to the immune system?
    • E.J. Fuchs, and P. Matzinger, Is cancer dangerous to the immune system? Semin. Immunol., 8(5): 271-280, 1996.
    • (1996) Semin. Immunol. , vol.8 , Issue.5 , pp. 271-280
    • Fuchs, E.J.1    Matzinger, P.2
  • 12
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • R. Medzhitov and C. Janeway, Jr., Innate immune recognition: Mechanisms and pathways. Immunol. Rev., 173: 89-97, 2000.
    • (2000) Immunol. Rev. , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway C., Jr.2
  • 13
    • 0035320526 scopus 로고    scopus 로고
    • A fresh look at tumor immunosurveillance and immunotherapy
    • M.J. Smyth, D.I. Godfrey, and J.A. Trapani, A fresh look at tumor immunosurveillance and immunotherapy. Nat. Immunol., 2(4): 293-299, 2001.
    • (2001) Nat. Immunol. , vol.2 , Issue.4 , pp. 293-299
    • Smyth, M.J.1    Godfrey, D.I.2    Trapani, J.A.3
  • 14
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • S. Sakaguchi, Regulatory T cells: Key controllers of immunologic self-tolerance. Cell., 101(5): 455-458, 2000.
    • (2000) Cell. , vol.101 , Issue.5 , pp. 455-458
    • Sakaguchi, S.1
  • 15
    • 0034572835 scopus 로고    scopus 로고
    • NKT cells and tumor immunity - A double-edged sword
    • M.J. Smyth and D.I. Godfrey, NKT cells and tumor immunity - A double-edged sword. Nat. Immunol., 1(6): 459-460, 2000.
    • (2000) Nat. Immunol. , vol.1 , Issue.6 , pp. 459-460
    • Smyth, M.J.1    Godfrey, D.I.2
  • 17
    • 0034901519 scopus 로고    scopus 로고
    • Assays for monitoring cellular immune responses to active immunotherapy of cancer
    • T.M. Clay, A.C. Hobeika, P.J. Mosca, H.K. Lyerly, and M.A. Morse, Assays for monitoring cellular immune responses to active immunotherapy of cancer. Clin. Cancer Res., 7(5): 1127-1135, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , Issue.5 , pp. 1127-1135
    • Clay, T.M.1    Hobeika, A.C.2    Mosca, P.J.3    Lyerly, H.K.4    Morse, M.A.5
  • 18
    • 0029919272 scopus 로고    scopus 로고
    • Immunotherapy of cancer with genetically modified tumor vaccines
    • E. Gilboa, Immunotherapy of cancer with genetically modified tumor vaccines. Semin. Oncol., 23(1): 101-107, 1996.
    • (1996) Semin. Oncol. , vol.23 , Issue.1 , pp. 101-107
    • Gilboa, E.1
  • 19
    • 0031875403 scopus 로고    scopus 로고
    • Experimental vaccine strategies for cancer immunotherapy
    • C.H. Chen and T.C. Wu, Experimental vaccine strategies for cancer immunotherapy. J. Biomed. Sci., 5(4): 231-252, 1998.
    • (1998) J. Biomed. Sci. , vol.5 , Issue.4 , pp. 231-252
    • Chen, C.H.1    Wu, T.C.2
  • 21
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues
    • M.R. Parkhurst, M.L. Salgaller, S. Southwood, P.F. Robbins, A. Sette, S.A. Rosenberg, and Y. Kawakami, Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues. J. Immunol., 157(6): 2539-2548, 1996.
    • (1996) J. Immunol. , vol.157 , Issue.6 , pp. 2539-2548
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6    Kawakami, Y.7
  • 22
    • 0029837404 scopus 로고    scopus 로고
    • Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides
    • M.L. Salgaller, F.M. Marincola, J.N. Cormier, and S.A. Rosenberg, Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides. Cancer Res., 56(20): 4749-4757, 1996.
    • (1996) Cancer Res. , vol.56 , Issue.20 , pp. 4749-4757
    • Salgaller, M.L.1    Marincola, F.M.2    Cormier, J.N.3    Rosenberg, S.A.4
  • 23
    • 0033759006 scopus 로고    scopus 로고
    • Melanoma vaccines: The paradox of T cell activation without clinical response
    • M.B. Nielsen, and F.M. Marincola, Melanoma vaccines: The paradox of T cell activation without clinical response. Cancer Chemother. Pharmacol., 46(Suppl): S62-S66, 2000.
    • (2000) Cancer Chemother. Pharmacol. , vol.46 , Issue.SUPPL.
    • Nielsen, M.B.1    Marincola, F.M.2
  • 24
    • 0034094357 scopus 로고    scopus 로고
    • Monitoring specific T-cell responses to melanoma vaccines: ELISPOT, tetramers, and beyond
    • T.F. Gajewski, Monitoring specific T-cell responses to melanoma vaccines: ELISPOT, tetramers, and beyond. Clin. Diagn. Lab. Immunol., 7(2): 141-144, 2000.
    • (2000) Clin. Diagn. Lab. Immunol. , vol.7 , Issue.2 , pp. 141-144
    • Gajewski, T.F.1
  • 25
    • 0034109873 scopus 로고    scopus 로고
    • Immune monitoring of cancer patients undergoing experimental immunotherapy
    • G. Shankar and M.L. Salgaller, Immune monitoring of cancer patients undergoing experimental immunotherapy. Curr. Opin. Mol. Ther., 2(1): 66-73, 2000.
    • (2000) Curr. Opin. Mol. Ther. , vol.2 , Issue.1 , pp. 66-73
    • Shankar, G.1    Salgaller, M.L.2
  • 27
    • 0035099076 scopus 로고    scopus 로고
    • Direct detection of cellular immune responses to cancer vaccines
    • P.J. Mosca, A.C. Hobeika, T.M. Clay, M.A. Morse, and H.K. Lyerly, Direct detection of cellular immune responses to cancer vaccines. Surgery, 129(3): 248-254, 2001.
    • (2001) Surgery , vol.129 , Issue.3 , pp. 248-254
    • Mosca, P.J.1    Hobeika, A.C.2    Clay, T.M.3    Morse, M.A.4    Lyerly, H.K.5
  • 30
    • 0021020342 scopus 로고
    • A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells
    • C.C. Czerkinsky, L.A. Nilsson, H. Nygren, O. Ouchterlony, and A. Tarkowski, A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J. Immunol. Methods., 65(1-2): 109-121, 1983.
    • (1983) J. Immunol. Methods. , vol.65 , Issue.1-2 , pp. 109-121
    • Czerkinsky, C.C.1    Nilsson, L.A.2    Nygren, H.3    Ouchterlony, O.4    Tarkowski, A.5
  • 33
    • 0034091625 scopus 로고    scopus 로고
    • Evaluation of the modified ELISPOT assay for gamma interferon production in cancer patients receiving antitumor vaccines
    • T. Asai, W.J. Storkus, and T. L. Whiteside, Evaluation of the modified ELISPOT assay for gamma interferon production in cancer patients receiving antitumor vaccines. Clin. Diagn. Lab. Immunol., 7(2): 145-154, 2000.
    • (2000) Clin. Diagn. Lab. Immunol. , vol.7 , Issue.2 , pp. 145-154
    • Asai, T.1    Storkus, W.J.2    Whiteside, T.L.3
  • 37
    • 0034834610 scopus 로고    scopus 로고
    • Development and validation of a gamma interferon ELISPOT assay for quantitation of cellular immune responses to vari cella-zoster virus
    • J.G. Smith, X. Liu, R.M. Kaufhold, J. Clair, and M.J. Caulfield, Development and validation of a gamma interferon ELISPOT assay for quantitation of cellular immune responses to varicella-zoster virus. Clin. Diagn. Lab. Immunol., 8(5): 871-879, 2001.
    • (2001) Clin. Diagn. Lab. Immunol. , vol.8 , Issue.5 , pp. 871-879
    • Smith, J.G.1    Liu, X.2    Kaufhold, R.M.3    Clair, J.4    Caulfield, M.J.5
  • 39
    • 0034096888 scopus 로고    scopus 로고
    • Cell viability improves following inhibition of cryopreservation-induced apoptosis
    • J.M. Baust, B. Van, and J.G. Baust, Cell viability improves following inhibition of cryopreservation-induced apoptosis. In Vitro Cell Dev. Biol. Anim., 36(4): 262-270, 2000.
    • (2000) In Vitro Cell Dev. Biol. Anim. , vol.36 , Issue.4 , pp. 262-270
    • Baust, J.M.1    Van, B.2    Baust, J.G.3
  • 41
    • 0034333232 scopus 로고    scopus 로고
    • Freezing induces artificial cleavage of apoptosis-related proteins in human bone marrow cells
    • J. Schmidt-Mende, E. Hellstrom-Lindberg, B. Joseph, and B. Zhivotovsky, Freezing induces artificial cleavage of apoptosis-related proteins in human bone marrow cells. J. Immunol. Methods, 245(1-2): 91-94, 2000.
    • (2000) J. Immunol. Methods , vol.245 , Issue.1-2 , pp. 91-94
    • Schmidt-Mende, J.1    Hellstrom-Lindberg, E.2    Joseph, B.3    Zhivotovsky, B.4
  • 42
    • 0035574488 scopus 로고    scopus 로고
    • A molecular basis of cryopreservation failure and its modulation to improve cell survival
    • J.M. Baust, M.J. Vogel, R. Van Buskirk, and J.G. Baust, A molecular basis of cryopreservation failure and its modulation to improve cell survival. Cell Transplant., 10(7): 561-571, 2001.
    • (2001) Cell Transplant. , vol.10 , Issue.7 , pp. 561-571
    • Baust, J.M.1    Vogel, M.J.2    Van Buskirk, R.3    Baust, J.G.4
  • 44
    • 0035371839 scopus 로고    scopus 로고
    • Flow cytometric evaluation of apoptosis, necrosis and recovery when culturing monocytes
    • P.K. Lund, A.B. Westvik, G.B. Joo, R. Ovstebo, K.B. Haug, and P. Kierulf, Flow cytometric evaluation of apoptosis, necrosis and recovery when culturing monocytes. J. Immunol. Methods, 252(1-2): 45-55, 2001.
    • (2001) J. Immunol. Methods , vol.252 , Issue.1-2 , pp. 45-55
    • Lund, P.K.1    Westvik, A.B.2    Joo, G.B.3    Ovstebo, R.4    Haug, K.B.5    Kierulf, P.6
  • 45
    • 0034981513 scopus 로고    scopus 로고
    • Caspase inhibition reduces apoptotic death of cryopreserved porcine hepatocytes
    • T. Yagi, J.A. Hardin, Y.M. Valenzuela, H. Miyoshi, G.J. Gores, and S.L. Nyberg, Caspase inhibition reduces apoptotic death of cryopreserved porcine hepatocytes. Hepatology, 33(6): 1432-1440, 2001.
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1432-1440
    • Yagi, T.1    Hardin, J.A.2    Valenzuela, Y.M.3    Miyoshi, H.4    Gores, G.J.5    Nyberg, S.L.6
  • 46
    • 0033081259 scopus 로고    scopus 로고
    • Type I interferons keep activated T cells alive
    • P. Marrack, J. Kappler, and T. Mitchell, Type I interferons keep activated T cells alive. J. Exp. Med., 189(3): 521-530, 1999.
    • (1999) J. Exp. Med. , vol.189 , Issue.3 , pp. 521-530
    • Marrack, P.1    Kappler, J.2    Mitchell, T.3
  • 52
    • 0035010979 scopus 로고    scopus 로고
    • IL-7 prevents both caspase-dependent and -independent pathways that lead to the spontaneous apoptosis of i-IEL
    • S. Yada, H. Nukina, K. Kishihara, N. Takamura, H. Yoshida, K. Inagaki-Ohara, K. Nomoto, and T. Lin, IL-7 prevents both caspase-dependent and -independent pathways that lead to the spontaneous apoptosis of i-IEL. Cell Immunol., 208(2): 88-95, 2001.
    • (2001) Cell Immunol. , vol.208 , Issue.2 , pp. 88-95
    • Yada, S.1    Nukina, H.2    Kishihara, K.3    Takamura, N.4    Yoshida, H.5    Inagaki-Ohara, K.6    Nomoto, K.7    Lin, T.8
  • 53
    • 0030749703 scopus 로고    scopus 로고
    • Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: Stat6 is probably not required for the effect of IL-4
    • A. Vella, T.K. Teague, J. Ihle, J. Kappler, and P. Marrack, Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: Stat6 is probably not required for the effect of IL-4. J. Exp. Med., 186(2): 325-330, 1997.
    • (1997) J. Exp. Med. , vol.186 , Issue.2 , pp. 325-330
    • Vella, A.1    Teague, T.K.2    Ihle, J.3    Kappler, J.4    Marrack, P.5
  • 55
    • 0033541599 scopus 로고    scopus 로고
    • Dendritic cell secretion of IL-15 is induced by recombinant huCD40LT and augments the stimulation of antigen-specific cytolytic T cells
    • J.S. Kuniyoshi, C.J. Kuniyoshi, A.M. Lim, F.Y. Wang, E.R. Bade, R. Lau, E.K. Thomas, and J.S. Weber, Dendritic cell secretion of IL-15 is induced by recombinant huCD40LT and augments the stimulation of antigen-specific cytolytic T cells. Cell Immunol., 193(1): 48-58, 1999.
    • (1999) Cell Immunol. , vol.193 , Issue.1 , pp. 48-58
    • Kuniyoshi, J.S.1    Kuniyoshi, C.J.2    Lim, A.M.3    Wang, F.Y.4    Bade, E.R.5    Lau, R.6    Thomas, E.K.7    Weber, J.S.8
  • 56
    • 0033941461 scopus 로고    scopus 로고
    • Cytokine-mediated protection of human dendritic cells from prostate cancer-induced apoptosis is regulated by the Bcl-2 family of proteins
    • G. Pirtskhalaishvili, G.V. Shurin, C. Esche, Q. Cai, R.R. Salup, S.N. Bykovskaia, M.T. Lotze, and M.R. Shurin, Cytokine-mediated protection of human dendritic cells from prostate cancer-induced apoptosis is regulated by the Bcl-2 family of proteins. British Journal of Cancer, 83(4): 506-513, 2000.
    • (2000) British Journal of Cancer , vol.83 , Issue.4 , pp. 506-513
    • Pirtskhalaishvili, G.1    Shurin, G.V.2    Esche, C.3    Cai, Q.4    Salup, R.R.5    Bykovskaia, S.N.6    Lotze, M.T.7    Shurin, M.R.8
  • 57
    • 0031716189 scopus 로고    scopus 로고
    • Immunization of patients with melanoma peptide vaccines: Immunologic assessment using the ELISPOT assay
    • H.A. Pass, S.L. Schwarz, J.R. Wunderlich, and S.A. Rosenberg, Immunization of patients with melanoma peptide vaccines: Immunologic assessment using the ELISPOT assay. Cancer J. Sci. Am., 4(5): 316-323, 1998.
    • (1998) Cancer J. Sci. Am. , vol.4 , Issue.5 , pp. 316-323
    • Pass, H.A.1    Schwarz, S.L.2    Wunderlich, J.R.3    Rosenberg, S.A.4
  • 58
    • 0032878254 scopus 로고    scopus 로고
    • A phase I trial of an HLA-A1 restricted MAGE-3 epitope peptide with incomplete Freund's adjuvant in patients with resected high-risk melanoma
    • J.S. Weber, F.L. Hua, L. Spears, V. Marty, C. Kuniyoshi, and E. Celis, A phase I trial of an HLA-A1 restricted MAGE-3 epitope peptide with incomplete Freund's adjuvant in patients with resected high-risk melanoma. J. Immunother., 22(5): 431-440, 1999.
    • (1999) J. Immunother. , vol.22 , Issue.5 , pp. 431-440
    • Weber, J.S.1    Hua, F.L.2    Spears, L.3    Marty, V.4    Kuniyoshi, C.5    Celis, E.6
  • 59
    • 0034064242 scopus 로고    scopus 로고
    • Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma
    • C. Scheibenbogen, A. Schmittel, U. Keilholz, T. Allgauer, U. Hofmann, R. Max, E. Thiel, and D. Schadendorf, Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma. J. Immunother., 23(2): 275-281, 2000.
    • (2000) J. Immunother. , vol.23 , Issue.2 , pp. 275-281
    • Scheibenbogen, C.1    Schmittel, A.2    Keilholz, U.3    Allgauer, T.4    Hofmann, U.5    Max, R.6    Thiel, E.7    Schadendorf, D.8
  • 60
    • 0035882548 scopus 로고    scopus 로고
    • Detection and quantification of CD8(+) T cells specific for HLA-A*0201-binding melanoma and viral peptides by the IFN-gamma-ELISPOT assay
    • M. Griffioen, M. Borghi, P.I. Schrier, and S. Osanto, Detection and quantification of CD8(+) T cells specific for HLA-A*0201-binding melanoma and viral peptides by the IFN-gamma-ELISPOT assay. Int. J. Cancer., 93(4): 549-555, 2001.
    • (2001) Int. J. Cancer. , vol.93 , Issue.4 , pp. 549-555
    • Griffioen, M.1    Borghi, M.2    Schrier, P.I.3    Osanto, S.4
  • 64
    • 0034551730 scopus 로고    scopus 로고
    • Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
    • J.L. Marshall, R.J. Hoyer, M.A. Toomey, K. Faraguna, P. Chang, E. Richmond, J.E. Pedicano, E. Gehan, R.A. Peck, P. Arlen, K.Y. Tsang, and J. Schlom, Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J. Clin. Oncol., 18(23): 3964-3973, 2000.
    • (2000) J. Clin. Oncol. , vol.18 , Issue.23 , pp. 3964-3973
    • Marshall, J.L.1    Hoyer, R.J.2    Toomey, M.A.3    Faraguna, K.4    Chang, P.5    Richmond, E.6    Pedicano, J.E.7    Gehan, E.8    Peck, R.A.9    Arlen, P.10    Tsang, K.Y.11    Schlom, J.12
  • 65
    • 0345390879 scopus 로고    scopus 로고
    • Decreased rate of progression and induction of tumor-specific immune response by adjuvant immunotherapy in stage IV melanoma
    • A.H. Enk, T. Wolfel, and J. Knop, Decreased rate of progression and induction of tumor-specific immune response by adjuvant immunotherapy in stage IV melanoma. Hautarzt., 50(2): 103-108, 1999.
    • (1999) Hautarzt. , vol.50 , Issue.2 , pp. 103-108
    • Enk, A.H.1    Wolfel, T.2    Knop, J.3
  • 66
    • 0032819985 scopus 로고    scopus 로고
    • High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals
    • M.J. Pittet, D. Valmori, P.R. Dunbar, D.E. Speiser, D. Lienard, F. Lejeune, K. Fleischhauer, V. Cerundolo, J.C. Cerottini, and P. Romero, High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J. Exp. Med., 190(5): 705-715, 1999.
    • (1999) J. Exp. Med. , vol.190 , Issue.5 , pp. 705-715
    • Pittet, M.J.1    Valmori, D.2    Dunbar, P.R.3    Speiser, D.E.4    Lienard, D.5    Lejeune, F.6    Fleischhauer, K.7    Cerundolo, V.8    Cerottini, J.C.9    Romero, P.10
  • 67
    • 17944367867 scopus 로고    scopus 로고
    • Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life
    • V. Rubio-Godoy, V. Dutoit, D. Rimoldi, D. Lienard, F. Lejeune, D. Speiser, P. Guillaume, J.C. Cerottini, P. Romero, and D. Valmori, Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life. Proc. Natl. Acad. Sci. USA., 98(18): 10302-10357, 2001.
    • (2001) Proc. Natl. Acad. Sci. USA. , vol.98 , Issue.18 , pp. 10302-10357
    • Rubio-Godoy, V.1    Dutoit, V.2    Rimoldi, D.3    Lienard, D.4    Lejeune, F.5    Speiser, D.6    Guillaume, P.7    Cerottini, J.C.8    Romero, P.9    Valmori, D.10
  • 68
    • 0035342556 scopus 로고    scopus 로고
    • Flow cytometric determination of intracellular or secreted IFN-gamma for the quantification of antigen reactive T cells
    • A.M. Asemissen, D. Nagorsen, U. Keilholz, A. Letsch, A. Schmittel, E. Thiel, and C. Scheibenbogen, Flow cytometric determination of intracellular or secreted IFN-gamma for the quantification of antigen reactive T cells. J. Immunol. Methods, 251(2): 101-108, 2001.
    • (2001) J. Immunol. Methods , vol.251 , Issue.2 , pp. 101-108
    • Asemissen, A.M.1    Nagorsen, D.2    Keilholz, U.3    Letsch, A.4    Schmittel, A.5    Thiel, E.6    Scheibenbogen, C.7
  • 69
    • 0031876634 scopus 로고    scopus 로고
    • Development of a dual color enzyme-linked immunospot assay for simultaneous detection of murine T helper type 1- and T helper type 2-cells
    • Y. Okamoto, T. Abe, T. Niwa, S. Mizuhashi, and M. Nishida, Development of a dual color enzyme-linked immunospot assay for simultaneous detection of murine T helper type 1- and T helper type 2-cells. Immunopharmacology, 39(2): 107-116, 1998.
    • (1998) Immunopharmacology , vol.39 , Issue.2 , pp. 107-116
    • Okamoto, Y.1    Abe, T.2    Niwa, T.3    Mizuhashi, S.4    Nishida, M.5
  • 71
    • 0029148642 scopus 로고
    • Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry
    • L.J. Picker, M.K. Singh, Z. Zdraveski, J.R. Treer, S.L. Waldrop, P.R. Bergstresser, and V.C. Maino, Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood, 86: 1408, 1995.
    • (1995) Blood , vol.86 , pp. 1408
    • Picker, L.J.1    Singh, M.K.2    Zdraveski, Z.3    Treer, J.R.4    Waldrop, S.L.5    Bergstresser, P.R.6    Maino, V.C.7
  • 72
    • 17144457321 scopus 로고    scopus 로고
    • Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry
    • M.A. Suni, L.J. Picker, and V.C. Maino, Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry. Journal of Immunological Methods, 212: 89, 1998.
    • (1998) Journal of Immunological Methods , vol.212 , pp. 89
    • Suni, M.A.1    Picker, L.J.2    Maino, V.C.3
  • 73
    • 0034116706 scopus 로고    scopus 로고
    • Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus, and cytomegalovirus by intracellular detection of cytokine expression
    • H. Asanuma, M. Sharp, H.T. Maecker, V.C. Maino, and A.M. Arvin, Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus, and cytomegalovirus by intracellular detection of cytokine expression. J. Infect. Dis., 181(3): 859-866, 2000.
    • (2000) J. Infect. Dis. , vol.181 , Issue.3 , pp. 859-866
    • Asanuma, H.1    Sharp, M.2    Maecker, H.T.3    Maino, V.C.4    Arvin, A.M.5
  • 77
    • 0032850575 scopus 로고    scopus 로고
    • Target structures of the CD8(+)-T-cell response to human cytomegalovirus: The 72-kilodalton major immediate-early protein revisited
    • F. Kern, I.P. Surel, N. Faulhaber, C. Frommel, J. Schneider-Mergener, C. Schonemann, P. Reinke, and H.D. Volk, Target structures of the CD8(+)-T-cell response to human cytomegalovirus: The 72-kilodalton major immediate-early protein revisited. J. Virol., 73(10): 8179-8184, 1999.
    • (1999) J. Virol. , vol.73 , Issue.10 , pp. 8179-8184
    • Kern, F.1    Surel, I.P.2    Faulhaber, N.3    Frommel, C.4    Schneider-Mergener, J.5    Schonemann, C.6    Reinke, P.7    Volk, H.D.8
  • 78
    • 0033485764 scopus 로고    scopus 로고
    • Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression
    • K.H. Lee, E. Wang, M.B. Nielsen, J. Wunderlich, S. Migueles, M. Connors, S.M. Steinberg, S.A. Rosenberg, and F.M. Marincola, Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. J. Immunol. 163(11): 6292-6300, 1999.
    • (1999) J. Immunol. , vol.163 , Issue.11 , pp. 6292-6300
    • Lee, K.H.1    Wang, E.2    Nielsen, M.B.3    Wunderlich, J.4    Migueles, S.5    Connors, M.6    Steinberg, S.M.7    Rosenberg, S.A.8    Marincola, F.M.9
  • 80
    • 0032533461 scopus 로고    scopus 로고
    • + memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis
    • + memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis. J. Immunol., 161(10): 5284-5295, 1998.
    • (1998) J. Immunol. , vol.161 , Issue.10 , pp. 5284-5295
    • Waldrop, S.L.1    Davis, K.A.2    Maino, V.C.3    Picker, L.J.4
  • 81
    • 0034192241 scopus 로고    scopus 로고
    • Optimization of whole blood antigen-specific cytokine assays for CD4(+) T cells
    • L.E. Nomura, J.M. Walker, and H.T. Maecker, Optimization of whole blood antigen-specific cytokine assays for CD4(+) T cells. Cytometry, 40(1): 60-68, 2000.
    • (2000) Cytometry , vol.40 , Issue.1 , pp. 60-68
    • Nomura, L.E.1    Walker, J.M.2    Maecker, H.T.3
  • 86
    • 0034850037 scopus 로고    scopus 로고
    • CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens
    • M.A. Suni, S.A. Ghanekar, D.W. Houck, H.T. Maecker, S.B. Wormsley, L.J. Picker, R.B. Moss, and VC. Maino, CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens. Eur. J. Immunol., 31(8): 2512-2520, 2001.
    • (2001) Eur. J. Immunol. , vol.31 , Issue.8 , pp. 2512-2520
    • Suni, M.A.1    Ghanekar, S.A.2    Houck, D.W.3    Maecker, H.T.4    Wormsley, S.B.5    Picker, L.J.6    Moss, R.B.7    Maino, V.C.8
  • 87
    • 0035023585 scopus 로고    scopus 로고
    • Gamma interferon expression in CD8(+) T cells is a marker for circulating cytotoxic T lymphocytes that recognize an HLA A2-restricted epitope of human cytomegalovirus phosphoprotein pp65
    • S.A. Ghanekar, L.E. Nomura, M.A. Suni, L.J. Picker, H.T. Maecker, and V.C. Maino, Gamma interferon expression in CD8(+) T cells is a marker for circulating cytotoxic T lymphocytes that recognize an HLA A2-restricted epitope of human cytomegalovirus phosphoprotein pp65. Clin. Diagn. Lab. Immunol., 8(3):628-631, 2001.
    • (2001) Clin. Diagn. Lab. Immunol. , vol.8 , Issue.3 , pp. 628-631
    • Ghanekar, S.A.1    Nomura, L.E.2    Suni, M.A.3    Picker, L.J.4    Maecker, H.T.5    Maino, V.C.6
  • 91
    • 0033960744 scopus 로고    scopus 로고
    • Detection of mycobacterium-specific interferon-gamma-producing human T lymphocytes by flow cytometry
    • P.A. Tilley, and J.N. Menon, Detection of mycobacterium-specific interferon-gamma-producing human T lymphocytes by flow cytometry. Apmis., 108(1): 57-66, 2000.
    • (2000) Apmis. , vol.108 , Issue.1 , pp. 57-66
    • Tilley, P.A.1    Menon, J.N.2
  • 92
    • 0034044954 scopus 로고    scopus 로고
    • Application of the intracellular gamma interferon assay to recalculate the potency of CD8(+) T-cell responses to herpes simplex virus
    • U. Kumaraguru, and B.T. Rouse, Application of the intracellular gamma interferon assay to recalculate the potency of CD8(+) T-cell responses to herpes simplex virus. J. Virol., 74(12): 5709-11, 2000.
    • (2000) J. Virol. , vol.74 , Issue.12 , pp. 5709-5711
    • Kumaraguru, U.1    Rouse, B.T.2
  • 96
    • 0034103551 scopus 로고    scopus 로고
    • Flow cytometric measurement of intracellular cytokines detects immune responses in MUC1 immunotherapy
    • V. Karanikas, J. Lodding, V.C. Maino, and I.F. McKenzie, Flow cytometric measurement of intracellular cytokines detects immune responses in MUC1 immunotherapy. Clin. Cancer Res., 6(3): 829-8372 2000.
    • (2000) Clin. Cancer Res. , vol.6 , Issue.3 , pp. 829-8372
    • Karanikas, V.1    Lodding, J.2    Maino, V.C.3    McKenzie, I.F.4
  • 98
    • 0032812103 scopus 로고    scopus 로고
    • Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: Correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood lymphocytes
    • A. Maraveyas, B. Baban, D. Kennard, G.A. Rook, M. Westby, J.M. Grange, P. Lydyard, J.L. Stanford, M. Jones, P. Selby, and A.G. Dalgleish, Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: Correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood lymphocytes. Ann. Oncol., 10(7): 817-824, 1999.
    • (1999) Ann. Oncol. , vol.10 , Issue.7 , pp. 817-824
    • Maraveyas, A.1    Baban, B.2    Kennard, D.3    Rook, G.A.4    Westby, M.5    Grange, J.M.6    Lydyard, P.7    Stanford, J.L.8    Jones, M.9    Selby, P.10    Dalgleish, A.G.11
  • 99
    • 0033062666 scopus 로고    scopus 로고
    • Evaluation of immunological responses in patients with ovarian cancer treated with the anti-idiotype vaccine ACA125 by determination of intracellular cytokines - A preliminary report
    • S. Reinartz, H. Boerner, S. Koehler, A. Von Ruecker, H. Schlebusch, and U. Wagner, Evaluation of immunological responses in patients with ovarian cancer treated with the anti-idiotype vaccine ACA125 by determination of intracellular cytokines - A preliminary report. Hybridoma., 18(1): 41-45, 1999.
    • (1999) Hybridoma. , vol.18 , Issue.1 , pp. 41-45
    • Reinartz, S.1    Boerner, H.2    Koehler, S.3    Von Ruecker, A.4    Schlebusch, H.5    Wagner, U.6
  • 100
    • 0033749649 scopus 로고    scopus 로고
    • Rapid quantification of SIV-specific CD8 T cell responses with recombinant vaccinia virus ELISPOT or cytokine flow cytometry
    • W.J. Moretto, L.A. Drohan, and D.F. Nixon, Rapid quantification of SIV-specific CD8 T cell responses with recombinant vaccinia virus ELISPOT or cytokine flow cytometry. Aids., 14(16): 2625-2627, 2000.
    • (2000) Aids , vol.14 , Issue.16 , pp. 2625-2627
    • Moretto, W.J.1    Drohan, L.A.2    Nixon, D.F.3
  • 101
    • 0026529908 scopus 로고
    • HLA-A2-peptide complexes: Refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides
    • D.N. Garboczi, D.T. Hung, and D.C. Wiley, HLA-A2-peptide complexes: Refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides. Proc. Natl. Acad. Sci. USA., 89(8): 3429-3433, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , Issue.8 , pp. 3429-3433
    • Garboczi, D.N.1    Hung, D.T.2    Wiley, D.C.3
  • 103
    • 0343183103 scopus 로고    scopus 로고
    • HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: Direct detection of immunodominant antigen-responsive cells
    • W.W. Kwok, A.W. Liu, E.J. Novak, J.A. Gebe, R.A. Ettinger, G.T. Nepom, S.N. Reymond, and D.M. Koelle, HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: Direct detection of immunodominant antigen-responsive cells. J. Immunol., 164(8): 4244-4249, 2000.
    • (2000) J. Immunol. , vol.164 , Issue.8 , pp. 4244-4249
    • Kwok, W.W.1    Liu, A.W.2    Novak, E.J.3    Gebe, J.A.4    Ettinger, R.A.5    Nepom, G.T.6    Reymond, S.N.7    Koelle, D.M.8
  • 105
    • 0034992147 scopus 로고    scopus 로고
    • Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset
    • E.J. Novak, S.A. Masewicz, A.W. Liu, A. Lernmark, W.W. Kwok, and G.T. Nepom, Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset. Int. Immunol., 13(6): 799-806, 2001.
    • (2001) Int. Immunol. , vol.13 , Issue.6 , pp. 799-806
    • Novak, E.J.1    Masewicz, S.A.2    Liu, A.W.3    Lernmark, A.4    Kwok, W.W.5    Nepom, G.T.6
  • 107
    • 0034650402 scopus 로고    scopus 로고
    • Use of fluorogenic histocompatibility leukocyte antigen-A*0201/HPV 16 E7 peptide complexes to isolate rare human cytotoxic T-lymphocyte-recognizing endogenous human papillomavirus antigens
    • S.J. Youde, P.R. Dunbar, E.M. Evans, A.N. Fiander, L.K. Borysiewicz, V. Cerundolo, and S. Man, Use of fluorogenic histocompatibility leukocyte antigen-A*0201/HPV 16 E7 peptide complexes to isolate rare human cytotoxic T-lymphocyte-recognizing endogenous human papillomavirus antigens. Cancer Res., 60(2): 365-371, 2000.
    • (2000) Cancer Res. , vol.60 , Issue.2 , pp. 365-371
    • Youde, S.J.1    Dunbar, P.R.2    Evans, E.M.3    Fiander, A.N.4    Borysiewicz, L.K.5    Cerundolo, V.6    Man, S.7
  • 109
    • 0034677055 scopus 로고    scopus 로고
    • Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
    • M.A. Daniels, and S.C. Jameson, Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers. J. Exp. Med., 191(2): 335-346, 2000.
    • (2000) J. Exp. Med. , vol.191 , Issue.2 , pp. 335-346
    • Daniels, M.A.1    Jameson, S.C.2
  • 110
    • 0035399799 scopus 로고    scopus 로고
    • Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR
    • G. Denkberg, C.J. Cohen, and Y. Reiter, Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR. J. Immunol., 167(1): 270-276, 2001.
    • (2001) J. Immunol. , vol.167 , Issue.1 , pp. 270-276
    • Denkberg, G.1    Cohen, C.J.2    Reiter, Y.3
  • 113
    • 0032789091 scopus 로고    scopus 로고
    • Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy
    • S.A. Kalams, P.J. Goulder, A.K. Shea, N.G. Jones, A.K. Trocha, G.S. Ogg, and B.D. Walker, Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy. J. Virol., 73(8): 6721-6728, 1999.
    • (1999) J. Virol. , vol.73 , Issue.8 , pp. 6721-6728
    • Kalams, S.A.1    Goulder, P.J.2    Shea, A.K.3    Jones, N.G.4    Trocha, A.K.5    Ogg, G.S.6    Walker, B.D.7
  • 117
    • 0032568259 scopus 로고    scopus 로고
    • Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood
    • P.R. Dunbar, G.S. Ogg, J. Chen, N. Rust, P. van der Bruggen, and V. Cerundolo, Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood. Curr. Biol., 8(7): 413-416, 1998.
    • (1998) Curr. Biol. , vol.8 , Issue.7 , pp. 413-416
    • Dunbar, P.R.1    Ogg, G.S.2    Chen, J.3    Rust, N.4    Van der Bruggen, P.5    Cerundolo, V.6
  • 118
    • 0032476616 scopus 로고    scopus 로고
    • Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes
    • P. Romero, P.R. Dunbar, D. Valmori, M. Pittet, G.S. Ogg, D. Rimoldi, J.L. Chen, D. Lienard, J.C. Cerottini, and V. Cerundolo, Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. J. Exp. Med., 188(9): 1641-1650, 1998.
    • (1998) J. Exp. Med. , vol.188 , Issue.9 , pp. 1641-1650
    • Romero, P.1    Dunbar, P.R.2    Valmori, D.3    Pittet, M.4    Ogg, G.S.5    Rimoldi, D.6    Chen, J.L.7    Lienard, D.8    Cerottini, J.C.9    Cerundolo, V.10
  • 125
    • 0035876923 scopus 로고    scopus 로고
    • Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: Implications of a novel approach for T cell monitoring in infectious and malignant diseases
    • M.J. Pittet, A. Zippelius, D.E. Speiser, M. Assenmacher, P. Guillaume, D. Valmori, D. Lienard, F. Lejeune, J.C. Cerottini, and P. Romero, Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: Implications of a novel approach for T cell monitoring in infectious and malignant diseases. J. Immunol., 166(12): 7634-7640, 2001.
    • (2001) J. Immunol. , vol.166 , Issue.12 , pp. 7634-7640
    • Pittet, M.J.1    Zippelius, A.2    Speiser, D.E.3    Assenmacher, M.4    Guillaume, P.5    Valmori, D.6    Lienard, D.7    Lejeune, F.8    Cerottini, J.C.9    Romero, P.10
  • 126
    • 0033152972 scopus 로고    scopus 로고
    • A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia
    • J.J. Molldrem, P.P. Lee, C. Wang, R.E. Champlin, and M.M. Davis, A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia. Cancer Res., 59(11): 2675-2681, 1999.
    • (1999) Cancer Res. , vol.59 , Issue.11 , pp. 2675-2681
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3    Champlin, R.E.4    Davis, M.M.5
  • 127
    • 0034544834 scopus 로고    scopus 로고
    • Competition of peptide-MHC class I tetrameric complexes with anti-CD3 provides evidence for specificity of peptide binding to the TCR complex
    • T.K. Hoffmann, V.S. Donnenberg, U. Friebe-Hoffmann, E.M. Meyer, C.R. Rinaldo, A.B. DeLeo, T.L. Whiteside, and A.D. Donnenberg, Competition of peptide-MHC class I tetrameric complexes with anti-CD3 provides evidence for specificity of peptide binding to the TCR complex. Cytometry, 41(4): 321-328, 2000.
    • (2000) Cytometry , vol.41 , Issue.4 , pp. 321-328
    • Hoffmann, T.K.1    Donnenberg, V.S.2    Friebe-Hoffmann, U.3    Meyer, E.M.4    Rinaldo, C.R.5    DeLeo, A.B.6    Whiteside, T.L.7    Donnenberg, A.D.8
  • 129
    • 0035127132 scopus 로고    scopus 로고
    • Simian immunodeficiency virus (SIV) infection of a rhesus macaque induces SIV-specific CD8(+) T cells with a defect in effector function that is reversible on extended interleukin-2 incubation
    • Y. Xiong, M.A. Luscher, J.D. Altman, M. Hulsey, H.L. Robinson, M. Ostrowski, B.H. Barber, and K.S. MacDonald, Simian immunodeficiency virus (SIV) infection of a rhesus macaque induces SIV-specific CD8(+) T cells with a defect in effector function that is reversible on extended interleukin-2 incubation. J. Virol., 75(6): 3028-3033, 2001.
    • (2001) J. Virol. , vol.75 , Issue.6 , pp. 3028-3033
    • Xiong, Y.1    Luscher, M.A.2    Altman, J.D.3    Hulsey, M.4    Robinson, H.L.5    Ostrowski, M.6    Barber, B.H.7    MacDonald, K.S.8
  • 132
    • 0035478651 scopus 로고    scopus 로고
    • Antigen-specific modulation of an immune response by in vivo administration of soluble MHC class I tetramers
    • R. Maile, B. Wang, W. Schooler, A. Meyer, E.J. Collins, and J.A. Frelinger, Antigen-specific modulation of an immune response by in vivo administration of soluble MHC class I tetramers. J. Immunol., 167(7): 3708-3714, 2001.
    • (2001) J. Immunol. , vol.167 , Issue.7 , pp. 3708-3714
    • Maile, R.1    Wang, B.2    Schooler, W.3    Meyer, A.4    Collins, E.J.5    Frelinger, J.A.6
  • 133
  • 135
    • 0026543967 scopus 로고
    • Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells
    • P.G. Coulie, M. Somville, F. Lehmann, P. Hainaut, F. Brasseur, R. Devos, and T. Boon, Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells. Int. J. Cancer, 50(2): 289-297, 1992.
    • (1992) Int. J. Cancer , vol.50 , Issue.2 , pp. 289-297
    • Coulie, P.G.1    Somville, M.2    Lehmann, F.3    Hainaut, P.4    Brasseur, F.5    Devos, R.6    Boon, T.7


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