Factors affecting the efficiency of CD8+ T cell cross-priming with exogenous antigens

Journal of Immunology

Volumn 166, Issue 12, 2001, Pages 7268-7275

  Maecker, H T ^a   Ghanekar, S A ^a   Suni, M A ^a   He, X S ^a   Picker, L J ^a   Maino, V C ^a  

^a BD Immunocytometry Systems   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BLOOD; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; DENDRITIC CELL; DOSE RESPONSE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; T LYMPHOCYTE;

EID: 0035877055     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.12.7268     Document Type: Article

References (36)

1. Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes
2. Pathways for the processing and presentation of antigens to T cells
3. Presentation of exogenous antigen with class I major histocompatibility complex molecules
4. Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules
5. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules
6. Class I-restricted processing and presentation of exogenous cell- associated antigen in vivo
7. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules
8. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules
9. Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis
10. Sensitization of MHC class I-restricted T cells to exogenous proteins: Evidence for an alternative class I-restricted antigen presentation pathway
11. Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages
12. Class I MHC presentation of exogenous antigens
13. A new foreign policy: MHC class I molecules monitor the outside world
14. Ovalbumin injected with complete Freund's adjuvant stimulates cytolytic responses
15. Listeriolysin generates a route for the presentation of exogenous antigens by major histocompatibility complex class I
16. Introduction of exogenous antigens into the MHC class I processing and presentation pathway by Drosophila antennapedia homeodomain primes cytotoxic T cells in vivo
17. Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide
18. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: Pathway of presentation and regulation by cytokines
19. Delivery of antigens to the MHC class I pathway using bacterial toxins
20. IL-3 enhances both presentation of exogenous particulate antigen in association with class I major histocompatibility antigen and generation of primary tumor-specific cytolytic T lymphocytes
21. Exploiting retrograde transport of Shiga-like toxin 1 for the delivery of exogenous antigens into the MHC class I presentation pathway
22. + cytotoxic T cells following immunization with soluble protein formulated with novel glycoside adjuvants
23. Induction of cytotoxic T lymphocyte activity by fusion-active peptide-containing virosomes
24. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
25. Dendritic cells efficiently cross-prime HLA class I-restricted cytolytic T lymphocytes when pulsed with both apoptotic and necrotic cells but not with soluble cell-derived lysates
26. Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry
27. + T cells
28. T-cell epitope mapping by flow cytometry
29. + memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis
30. + T cells in peripheral blood and liver using peptide-MHC tetramers
31. Proliferating dendritic cell progenitors in human blood
32. Analysis of CD8 T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides
33. Detection of CD4 T cell responses to a tumor vaccine by cytokine flow cytometry
34. Viral immune evasion due to persistence of activated T cells without effector function
35. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
36. + memory T cell subsets in persistent EBV infection are differentiated by migratory receptor expression