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Volumn 412, Issue 2, 2003, Pages 157-169

E2F and cell cycle control: A double-edged sword

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; ATM PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; DIHYDROFOLATE REDUCTASE; DNA DIRECTED DNA POLYMERASE ALPHA; HISTONE DEACETYLASE; MINICHROMOSOME MAINTENANCE PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN MDM2; PROTEIN P107; PROTEIN P130; PROTEIN P300; PROTEIN P73; RETINOBLASTOMA PROTEIN; SMAD3 PROTEIN; THYMIDINE KINASE; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F4; TRANSCRIPTION FACTOR E2F5; TRANSCRIPTION FACTOR E2F6; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 0037445901     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9861(03)00054-7     Document Type: Short Survey
Times cited : (192)

References (129)
  • 1
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 2
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumour suppressor protein and viral oncoproteins
    • Nevins J.R. E2F: a link between the Rb tumour suppressor protein and viral oncoproteins. Science. 258:1992;424-429.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 3
    • 0023662316 scopus 로고
    • An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells
    • La Thangue N.B., Rigby P.W. An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell. 49:1987;507-513.
    • (1987) Cell , vol.49 , pp. 507-513
    • La Thangue, N.B.1    Rigby, P.W.2
  • 4
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRb-family proteins
    • Dyson N. The regulation of E2F by pRb-family proteins. Genes Dev. 12:1998;2245-2262.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 7
    • 0034609864 scopus 로고    scopus 로고
    • A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
    • Lissy N.A., Davis P.K., Irwin M., Kaelin W.G., Dowdy S.F. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature. 407:2000;642-644.
    • (2000) Nature , vol.407 , pp. 642-644
    • Lissy, N.A.1    Davis, P.K.2    Irwin, M.3    Kaelin, W.G.4    Dowdy, S.F.5
  • 9
    • 0025869428 scopus 로고
    • Adenovirus E1A prevents the retinoblastoma gene product from complexing with a cellular transcription factor
    • Bandara L.R., La Thangue N.B. Adenovirus E1A prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature. 351:1991;494-497.
    • (1991) Nature , vol.351 , pp. 494-497
    • Bandara, L.R.1    La Thangue, N.B.2
  • 10
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 11
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend S.H., Bernards R., Rogelj S., Weinberg R.A., Rapaport J.M., Albert D.M., Drija T.P. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature. 323:1986;643-646.
    • (1986) Nature , vol.323 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5    Albert, D.M.6    Drija, T.P.7
  • 12
    • 0031052563 scopus 로고    scopus 로고
    • Retinoblastoma protein in growth suppression and death protection
    • Wang J.Y. Retinoblastoma protein in growth suppression and death protection. Curr. Opin. Genet. Dev. 7:1997;39-45.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 39-45
    • Wang, J.Y.1
  • 13
    • 0031831681 scopus 로고    scopus 로고
    • The retinoblastoma gene family: Cousins with overlapping interests
    • Mulligan G., Jacks T. The retinoblastoma gene family: cousins with overlapping interests. Trends Genet. 14:1998;223-229.
    • (1998) Trends Genet. , vol.14 , pp. 223-229
    • Mulligan, G.1    Jacks, T.2
  • 17
    • 0031935648 scopus 로고    scopus 로고
    • Control of pRb phosphorylation
    • Mittnacht S. Control of pRb phosphorylation. Curr. Opin. Genet. Dev. 8:1998;21-27.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 21-27
    • Mittnacht, S.1
  • 18
    • 0029583648 scopus 로고
    • Regulation of the cyclin E gene by the transcription factor E2F1
    • Ohtani K., DeGregori J., Nevins J.R. Regulation of the cyclin E gene by the transcription factor E2F1. Proc. Natl. Acad. Sci. USA. 92:1995;12146-12150.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12146-12150
    • Ohtani, K.1    DeGregori, J.2    Nevins, J.R.3
  • 20
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    • Lundberg A.S., Weinberg R.A. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol. 18:1998;753-761.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 21
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr C.J., Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1999;1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 22
    • 0029912789 scopus 로고    scopus 로고
    • Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal
    • de la Luna S., Burden M.J., Lee C.-W., La Thangue N.B. Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal. J. Cell. Sci. 109:1996;2443-2452.
    • (1996) J. Cell. Sci. , vol.109 , pp. 2443-2452
    • De la Luna, S.1    Burden, M.J.2    Lee, C.-W.3    La Thangue, N.B.4
  • 23
    • 0034014308 scopus 로고    scopus 로고
    • Complex transcriptional regulatory mechanisms control expression of the E2F3 locus
    • Adams M.R., Sears R., Nuckolls F., Leone G., Nevins J.R. Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. Mol. Cell. Biol. 20:2000;3633-3639.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3633-3639
    • Adams, M.R.1    Sears, R.2    Nuckolls, F.3    Leone, G.4    Nevins, J.R.5
  • 26
    • 0029066888 scopus 로고
    • Cloning and characterisation of human DP2, a novel dimerisation partner of E2F
    • Zhang Y., Chellappan S.P. Cloning and characterisation of human DP2, a novel dimerisation partner of E2F. Oncogene. 10:1995;2085-2093.
    • (1995) Oncogene , vol.10 , pp. 2085-2093
    • Zhang, Y.1    Chellappan, S.P.2
  • 27
    • 0030688065 scopus 로고    scopus 로고
    • Subunit composition determines E2F DNA-binding site specificity
    • Tao Y., Kassatly R.F., Cress D.W., Horowitz J.M. Subunit composition determines E2F DNA-binding site specificity. Mol. Cell. Biol. 17:1997;6994-7007.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6994-7007
    • Tao, Y.1    Kassatly, R.F.2    Cress, D.W.3    Horowitz, J.M.4
  • 31
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F-1 induces quiescent cells to enter S phase
    • Johnson D.G., Schwarz J.K., Cress W.D., Nevins J.R. Expression of transcription factor E2F-1 induces quiescent cells to enter S phase. Nature. 365:1993;349-352.
    • (1993) Nature , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 32
    • 0029747143 scopus 로고    scopus 로고
    • Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs
    • Asano M., Nevins J.R., Wharton R.P. Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev. 10:1996;1422-1432.
    • (1996) Genes Dev. , vol.10 , pp. 1422-1432
    • Asano, M.1    Nevins, J.R.2    Wharton, R.P.3
  • 33
    • 0030053130 scopus 로고    scopus 로고
    • Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4a mediated growth suppression
    • Lukas J., Petersen B.O., Holm K., Bartek J., Helin K. Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4a mediated growth suppression. Mol. Cell. Biol. 16:1996;1047-1057.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1047-1057
    • Lukas, J.1    Petersen, B.O.2    Holm, K.3    Bartek, J.4    Helin, K.5
  • 34
    • 0032417694 scopus 로고    scopus 로고
    • Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts
    • Wang Z.M., Yang H., Livingston D.M. Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts. Proc. Natl. Acad. Sci. USA. 95:1998;15583-15586.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15583-15586
    • Wang, Z.M.1    Yang, H.2    Livingston, D.M.3
  • 35
    • 0030008768 scopus 로고    scopus 로고
    • Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1
    • Wu C.-L., Classon M., Dyson N., Harlow E. Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1. Mol. Cell. Biol. 16:1996;3698-3706.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3698-3706
    • Wu, C.-L.1    Classon, M.2    Dyson, N.3    Harlow, E.4
  • 37
    • 0028826881 scopus 로고
    • E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity
    • DeGregori J., Leone G., Ohtani K., Miron A., Nevins J.R. E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. Genes Dev. 9:1995;2873-2887.
    • (1995) Genes Dev. , vol.9 , pp. 2873-2887
    • DeGregori, J.1    Leone, G.2    Ohtani, K.3    Miron, A.4    Nevins, J.R.5
  • 39
    • 0030113694 scopus 로고    scopus 로고
    • E2F-1 but not E2F-4 can overcome p16-induced G1 cell cycle arrest
    • Mann D.J., Jones N.C. E2F-1 but not E2F-4 can overcome p16-induced G1 cell cycle arrest. Curr. Biol. 6:1996;474-483.
    • (1996) Curr. Biol. , vol.6 , pp. 474-483
    • Mann, D.J.1    Jones, N.C.2
  • 40
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin X.-Q., Livingston D.M., Kaelin W.G. Jr., Adams P.D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;10918-10922.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin W.G., Jr.3    Adams, P.D.4
  • 41
    • 0033083003 scopus 로고    scopus 로고
    • Mechanism of transcriptional repression of E2F by the retinoblastoma tumour suppressor protein
    • Ross J.F., Lui X., Dynlacht B.D. Mechanism of transcriptional repression of E2F by the retinoblastoma tumour suppressor protein. Mol. Cell. 3:1999;195-205.
    • (1999) Mol. Cell , vol.3 , pp. 195-205
    • Ross, J.F.1    Lui, X.2    Dynlacht, B.D.3
  • 42
    • 0033515424 scopus 로고    scopus 로고
    • Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFβ, and contact inhibition
    • Zhang H., Postigo A.A., Dean D.C. Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFβ, and contact inhibition. Cell. 97:1999;53-61.
    • (1999) Cell , vol.97 , pp. 53-61
    • Zhang, H.1    Postigo, A.A.2    Dean, D.C.3
  • 43
    • 0035119507 scopus 로고    scopus 로고
    • Active repression and E2F inhibition by pRb are biochemically distinguishable
    • Ross J.F., Naar A., Cam H., Gregory R., Dynlacht B.D. Active repression and E2F inhibition by pRb are biochemically distinguishable. Genes Dev. 15:2001;392-397.
    • (2001) Genes Dev. , vol.15 , pp. 392-397
    • Ross, J.F.1    Naar, A.2    Cam, H.3    Gregory, R.4    Dynlacht, B.D.5
  • 45
    • 0032549001 scopus 로고    scopus 로고
    • Rb interacts with histone deacetylase to repress transcription
    • Luo R.X., Postigo A.A., Dean D.C. Rb interacts with histone deacetylase to repress transcription. Cell. 92:1998;463-473.
    • (1998) Cell , vol.92 , pp. 463-473
    • Luo, R.X.1    Postigo, A.A.2    Dean, D.C.3
  • 48
    • 0034737290 scopus 로고    scopus 로고
    • Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
    • Zhang H., Gavin M., Dahiya A., Postigo A.A., Ma D., Luo R.X., Harbour J.W., Dean D.C. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell. 101:2000;78-89.
    • (2000) Cell , vol.101 , pp. 78-89
    • Zhang, H.1    Gavin, M.2    Dahiya, A.3    Postigo, A.A.4    Ma, D.5    Luo, R.X.6    Harbour, J.W.7    Dean, D.C.8
  • 49
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: Expanding roles and emerging paradigms
    • Harbour J.W., Dean D.C. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 14:2000;2393-2409.
    • (2000) Genes Dev. , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 51
    • 0035282573 scopus 로고    scopus 로고
    • Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
    • Lachner M., O'Carroll D., Rea S., Mechtler K., Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. 410:2001;116-120.
    • (2001) Nature , vol.410 , pp. 116-120
    • Lachner, M.1    O'Carroll, D.2    Rea, S.3    Mechtler, K.4    Jenuwein, T.5
  • 52
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., Allis D. Translating the histone code. Science. 293:2001;1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, D.2
  • 53
    • 0027985749 scopus 로고
    • E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo
    • Beijersbergen R.L., Kerkhoven R.M., Zhu L., Carlee L., Voorhoeve P.M., Bernards R. E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev. 8:1994;2680-2690.
    • (1994) Genes Dev. , vol.8 , pp. 2680-2690
    • Beijersbergen, R.L.1    Kerkhoven, R.M.2    Zhu, L.3    Carlee, L.4    Voorhoeve, P.M.5    Bernards, R.6
  • 55
    • 0030774301 scopus 로고    scopus 로고
    • Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors
    • Allen K.E., de la Luna S., Kerkhoven R.M., Bernards R., La Thangue N.B. Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors. J. Cell Biol. 110:1997;2810-2831.
    • (1997) J. Cell Biol. , vol.110 , pp. 2810-2831
    • Allen, K.E.1    De la Luna, S.2    Kerkhoven, R.M.3    Bernards, R.4    La Thangue, N.B.5
  • 56
    • 0039227088 scopus 로고    scopus 로고
    • Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
    • Muller H., Moroni M.C., Vigo E., Petersen B.O., Bartek J., Helin K. Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol. Cell. Biol. 17:1997;5508-5520.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5508-5520
    • Muller, H.1    Moroni, M.C.2    Vigo, E.3    Petersen, B.O.4    Bartek, J.5    Helin, K.6
  • 57
    • 0030667320 scopus 로고    scopus 로고
    • E2F activity is regulated by cell-cycle-dependent changes in subcellular localization
    • Verona R., Moberg K., Estes S., Starz M., Vernon J.P., Lees J.A. E2F activity is regulated by cell-cycle-dependent changes in subcellular localization. Mol. Cell. Biol. 17:1997;7268-7282.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 7268-7282
    • Verona, R.1    Moberg, K.2    Estes, S.3    Starz, M.4    Vernon, J.P.5    Lees, J.A.6
  • 58
    • 0029991715 scopus 로고    scopus 로고
    • Nuclear localisation of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members
    • Magae J., We C., Illenye S., Harlow E., Heintz N.H. Nuclear localisation of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. J. Cell. Sci. 109:1996;1717-1726.
    • (1996) J. Cell. Sci. , vol.109 , pp. 1717-1726
    • Magae, J.1    We, C.2    Illenye, S.3    Harlow, E.4    Heintz, N.H.5
  • 60
    • 0344557684 scopus 로고    scopus 로고
    • E2F-4 switches from p130 to p107 and pRb in response to cell cycle re-entry
    • Morberg K., Starz M.A., Lees J.A. E2F-4 switches from p130 to p107 and pRb in response to cell cycle re-entry. Mol. Cell. Biol. 12:1996;232-239.
    • (1996) Mol. Cell. Biol. , vol.12 , pp. 232-239
    • Morberg, K.1    Starz, M.A.2    Lees, J.A.3
  • 61
    • 0026568215 scopus 로고
    • Cell cycle regulation of the human CDC2 gene
    • Dalton S. Cell cycle regulation of the human CDC2 gene. EMBO J. 11:1992;1797-1804.
    • (1992) EMBO J. , vol.11 , pp. 1797-1804
    • Dalton, S.1
  • 62
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
    • Lam E.W., Watson R.J. An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J. 12:1993;2705-2713.
    • (1993) EMBO J. , vol.12 , pp. 2705-2713
    • Lam, E.W.1    Watson, R.J.2
  • 63
    • 0028276864 scopus 로고
    • Multiple DNA elements are required for the growth regulation of the mouse E2F-1 promoter
    • Hsiao K.M., McMahon S.L., Farnham P.J. Multiple DNA elements are required for the growth regulation of the mouse E2F-1 promoter. Genes Dev. 8:1994;1526-1537.
    • (1994) Genes Dev. , vol.8 , pp. 1526-1537
    • Hsiao, K.M.1    McMahon, S.L.2    Farnham, P.J.3
  • 64
    • 0034175616 scopus 로고    scopus 로고
    • Analysis of promoter binding by the E2F and pRb families in vivo: Distinct E2F proteins mediate activation and repression
    • Takahashi Y., Rayman J.B., Dynlacht B.D. Analysis of promoter binding by the E2F and pRb families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev. 14:2000;804-816.
    • (2000) Genes Dev. , vol.14 , pp. 804-816
    • Takahashi, Y.1    Rayman, J.B.2    Dynlacht, B.D.3
  • 65
    • 0028841550 scopus 로고
    • In vivo structure of the human cdc2 promoter: Release of a p130-E2F4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression
    • Tommasi S., Pfeifer G.P. In vivo structure of the human cdc2 promoter: release of a p130-E2F4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression. Mol. Cell. Biol. 15:1995;6901-6913.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6901-6913
    • Tommasi, S.1    Pfeifer, G.P.2
  • 66
    • 0029992819 scopus 로고    scopus 로고
    • Cyclin A expression is under negative transcriptional control during the cell cycle
    • Huet X., Rech J., Plet A., Vie A., Blanchard J.M. Cyclin A expression is under negative transcriptional control during the cell cycle. Mol. Cell. Biol. 16:1996;3789-3798.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3789-3798
    • Huet, X.1    Rech, J.2    Plet, A.3    Vie, A.4    Blanchard, J.M.5
  • 68
    • 0033783177 scopus 로고    scopus 로고
    • Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators
    • Morris L., Allen K.E., La Thangue N.B. Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators. Nat. Cell Biol. 2:2000;232-239.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 232-239
    • Morris, L.1    Allen, K.E.2    La Thangue, N.B.3
  • 69
    • 0037067653 scopus 로고    scopus 로고
    • E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression
    • Chen C., Kang Y., Siegel P.M., Massague J. E2F4/5 and p107 as Smad cofactors linking the TGFβ receptor to c-myc repression. Cell. 110:2002;19-32.
    • (2002) Cell , vol.110 , pp. 19-32
    • Chen, C.1    Kang, Y.2    Siegel, P.M.3    Massague, J.4
  • 70
    • 0035852632 scopus 로고    scopus 로고
    • The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
    • Trimarchi J.M., Fairchild B., Wen J., Lees J.A. The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc. Natl. Acad. Sci. USA. 98:2001;1519-1524.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1519-1524
    • Trimarchi, J.M.1    Fairchild, B.2    Wen, J.3    Lees, J.A.4
  • 71
    • 0037052539 scopus 로고    scopus 로고
    • A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in Go cells
    • Ogawa H., Ishiguro K., Gaubatz S., Livingston D., Nakatani Y. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in Go cells. Science. 296:2002;1132-1136.
    • (2002) Science , vol.296 , pp. 1132-1136
    • Ogawa, H.1    Ishiguro, K.2    Gaubatz, S.3    Livingston, D.4    Nakatani, Y.5
  • 72
    • 0035833726 scopus 로고    scopus 로고
    • General transcription factors bind promoters repressed by Polycomb group proteins
    • Breiling A., Turner B.M., Bianchi M.E., Orlando V. General transcription factors bind promoters repressed by Polycomb group proteins. Nature. 412:2001;651-655.
    • (2001) Nature , vol.412 , pp. 651-655
    • Breiling, A.1    Turner, B.M.2    Bianchi, M.E.3    Orlando, V.4
  • 73
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclinA-dependent protein kinase
    • Krek W., Ewen M.E., Shirodkar S., Arany Z., Kaelin W.G., Livingston D.M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclinA-dependent protein kinase. Cell. 78:1994;161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin, W.G.5    Livingston, D.M.6
  • 74
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
    • Xu M., Sheppard K.A., Peng C.Y., Yee A.S., Piwnica-Worms H Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell. Biol. 14:1994;8420-8431.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8420-8431
    • Xu, M.1    Sheppard, K.A.2    Peng, C.Y.3    Yee, A.S.4    Piwnica-Worms, H.5
  • 75
    • 0029559027 scopus 로고
    • Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
    • Krek W, Xu G., Livingston D.M. Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell. 83:1995;1149-1158.
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 76
    • 0032540498 scopus 로고    scopus 로고
    • The role of protein stability in the cell cycle and cancer
    • Elledge S.J., Harper J.W. The role of protein stability in the cell cycle and cancer. Biochem. Biophys. Acta. 1377:1998;M61-M70.
    • (1998) Biochem. Biophys. Acta , vol.1377
    • Elledge, S.J.1    Harper, J.W.2
  • 77
    • 0029797841 scopus 로고    scopus 로고
    • Deregulation of E2F by the ubiquitin-proteasome pathway: Regulation by retinoblastoma family proteins and adenovirus transforming proteins
    • Hateboer G., Kerkhoven R.M., Shvarts A., Bernards R., Beijerbergen R.L. Deregulation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins. Genes Dev. 10:1996;2960-2970.
    • (1996) Genes Dev. , vol.10 , pp. 2960-2970
    • Hateboer, G.1    Kerkhoven, R.M.2    Shvarts, A.3    Bernards, R.4    Beijerbergen, R.L.5
  • 78
    • 0029820095 scopus 로고    scopus 로고
    • The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
    • Hofmann F., Martelli F., Livingston D.M., Wang Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10:1996;2949-2959.
    • (1996) Genes Dev. , vol.10 , pp. 2949-2959
    • Hofmann, F.1    Martelli, F.2    Livingston, D.M.3    Wang, Z.4
  • 80
    • 0033998439 scopus 로고    scopus 로고
    • Apoptotic and growth-promoting activity of E2F modulated by MDM2
    • Loughran O., La Thangue N.B. Apoptotic and growth-promoting activity of E2F modulated by MDM2. Mol. Cell. Biol. 20:2000;2186-2197.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2186-2197
    • Loughran, O.1    La Thangue, N.B.2
  • 81
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase for tumour suppressor p53
    • Honda R., Tanaka H., Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase for tumour suppressor p53. FEBS Lett. 420:1997;25-27.
    • (1997) FEBS Lett. , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 84
    • 0029997146 scopus 로고    scopus 로고
    • The CBP co-activator stimulates E2F1/DP1 activity
    • Trouche D., Cook A., Kouzarides T. The CBP co-activator stimulates E2F1/DP1 activity. Nucleic Acids Res. 24:1996;4139-4145.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4139-4145
    • Trouche, D.1    Cook, A.2    Kouzarides, T.3
  • 85
    • 0034916613 scopus 로고    scopus 로고
    • P300/CBP proteins: HATs for transcriptional bridges and scaffolds
    • Chan H.M., La Thangue N.B. P300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell. Sci. 114:2001;2363-2373.
    • (2001) J. Cell. Sci. , vol.114 , pp. 2363-2373
    • Chan, H.M.1    La Thangue, N.B.2
  • 88
    • 0028296414 scopus 로고
    • Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor
    • Eckner R., Ewen M.E., Newsome D., Gerdes M., DeCaprio J.A., Lawrence J.B., Livingston D.M. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8:1994;869-884.
    • (1994) Genes Dev. , vol.8 , pp. 869-884
    • Eckner, R.1    Ewen, M.E.2    Newsome, D.3    Gerdes, M.4    DeCaprio, J.A.5    Lawrence, J.B.6    Livingston, D.M.7
  • 92
    • 0032528027 scopus 로고    scopus 로고
    • E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
    • Leone G., Degregori J., Yan Z., Jakoi L., Ishida S., Williams R.S., Nevins J.R. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 12:1998;2120-2130.
    • (1998) Genes Dev. , vol.12 , pp. 2120-2130
    • Leone, G.1    Degregori, J.2    Yan, Z.3    Jakoi, L.4    Ishida, S.5    Williams, R.S.6    Nevins, J.R.7
  • 98
    • 15444353328 scopus 로고    scopus 로고
    • PRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes
    • Hurford R.K., Cobrinik D., Lee M.H., Dyson N. pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 11:1997;1447-1463.
    • (1997) Genes Dev. , vol.11 , pp. 1447-1463
    • Hurford, R.K.1    Cobrinik, D.2    Lee, M.H.3    Dyson, N.4
  • 99
    • 0033592688 scopus 로고    scopus 로고
    • Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
    • Lukas C., Sorensen C.S., Kramer E., Santoni-Rugiu E., Lindeneg C., Peters J., Bartek J., Lukas J. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. Nature. 401:1999;815-818.
    • (1999) Nature , vol.401 , pp. 815-818
    • Lukas, C.1    Sorensen, C.S.2    Kramer, E.3    Santoni-Rugiu, E.4    Lindeneg, C.5    Peters, J.6    Bartek, J.7    Lukas, J.8
  • 100
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases and cdk inhibitors in human cancer
    • Hall M., Peters G. Genetic alterations of cyclins, cyclin-dependent kinases and cdk inhibitors in human cancer. Adv. Cancer Res. 68:1996;67-108.
    • (1996) Adv. Cancer Res. , vol.68 , pp. 67-108
    • Hall, M.1    Peters, G.2
  • 101
    • 0029808234 scopus 로고    scopus 로고
    • Enhanced protein stability: A novel mechanism of D-type cyclin overabundance identified in human sarcoma cells
    • Welcker M., Lukas J., Strauss M., Bartek J. Enhanced protein stability: a novel mechanism of D-type cyclin overabundance identified in human sarcoma cells. Oncogene. 13:1996;419-425.
    • (1996) Oncogene , vol.13 , pp. 419-425
    • Welcker, M.1    Lukas, J.2    Strauss, M.3    Bartek, J.4
  • 102
    • 0029052951 scopus 로고
    • Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition
    • Koh J., Enders G.H., Dynlacht B.D., Harlow E. Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature. 375:1995;506-510.
    • (1995) Nature , vol.375 , pp. 506-510
    • Koh, J.1    Enders, G.H.2    Dynlacht, B.D.3    Harlow, E.4
  • 104
    • 0033602410 scopus 로고    scopus 로고
    • Balancing proliferation and apoptosis in vivo: The Goldilocks theory of E2F/DP action
    • Yamasaki L. Balancing proliferation and apoptosis in vivo: the Goldilocks theory of E2F/DP action. Biochem. Biopohys. Acta. 1423:1999;M9-M15.
    • (1999) Biochem. Biopohys. Acta , vol.1423
    • Yamasaki, L.1
  • 108
    • 0030850752 scopus 로고    scopus 로고
    • E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh J.K., Fredersdorf S., Kouzarides T., Martin K., Lu X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev. 11:1997;1840-1852.
    • (1997) Genes Dev. , vol.11 , pp. 1840-1852
    • Hsieh, J.K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 109
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F1
    • Phillips A.C., Bates S., Ryan K.M., Helin K., Vousden K.H. Induction of DNA synthesis and apoptosis are separable functions of E2F1. Genes Dev. 11:1997;1853-1863.
    • (1997) Genes Dev. , vol.11 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 110
    • 0033231615 scopus 로고    scopus 로고
    • E2F1 potentiates cell death by blocking anti-apoptotic signalling pathways
    • Phillips A.C., Ernst M.K., Bates S., Rice N.R., Vousden K.H. E2F1 potentiates cell death by blocking anti-apoptotic signalling pathways. Mol. Cell. 4:1999;771-781.
    • (1999) Mol. Cell , vol.4 , pp. 771-781
    • Phillips, A.C.1    Ernst, M.K.2    Bates, S.3    Rice, N.R.4    Vousden, K.H.5
  • 111
    • 0036133649 scopus 로고    scopus 로고
    • ARF is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo
    • ARF is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo Mol. Cell. Biol. 22:2002;370-377.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 370-377
    • Tolbert, D.1    Lu, X.2    Yin, C.3    Tantama, M.4    Van Dyke, T.5
  • 112
    • 0032939925 scopus 로고    scopus 로고
    • Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
    • Blattner C., Sparks A., Lane D. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol. Cell. Biol. 19:1999;3704-3713.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3704-3713
    • Blattner, C.1    Sparks, A.2    Lane, D.3
  • 113
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • Lin W.C., Lin F.T., Nevins J.R. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev. 15:2001;1833-1844.
    • (2001) Genes Dev. , vol.15 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 118
    • 0035092886 scopus 로고    scopus 로고
    • DNA replication control through interaction of E2F-RB and the origin recognition complex
    • Bosco G., Du W., Orr-Weaver T.L. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat. Cell Biol. 3:2001;289-295.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 289-295
    • Bosco, G.1    Du, W.2    Orr-Weaver, T.L.3
  • 120
    • 0028784499 scopus 로고
    • Inhibition of in vitro myogenic differentiation by cellular transcription factor E2F-1
    • Wang J., Helin K., Jin P., Nadal-Ginard B. Inhibition of in vitro myogenic differentiation by cellular transcription factor E2F-1. Cell Growth Differ. 6:1995;1299-1306.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1299-1306
    • Wang, J.1    Helin, K.2    Jin, P.3    Nadal-Ginard, B.4
  • 121
    • 0034622103 scopus 로고    scopus 로고
    • E2F-1 induces proliferation-specific genes and suppresses squamous differentiation-specific genes in human epidermal keratinocytes
    • Dicker A.J., Popa C., Dahler A.L., Serewko M.M., Hilditch-Maguire P.A., Frazer I.H., Saunders N.A. E2F-1 induces proliferation-specific genes and suppresses squamous differentiation-specific genes in human epidermal keratinocytes. Oncogene. 19:2000;2887-2894.
    • (2000) Oncogene , vol.19 , pp. 2887-2894
    • Dicker, A.J.1    Popa, C.2    Dahler, A.L.3    Serewko, M.M.4    Hilditch-Maguire, P.A.5    Frazer, I.H.6    Saunders, N.A.7
  • 123
    • 0026744563 scopus 로고
    • Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
    • Lee E.Y., Chang C.Y., Hu N., Wang Y.C., Lai C.C., Herrup K., Lee W.H., Bradley A. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature. 359:1992;288-294.
    • (1992) Nature , vol.359 , pp. 288-294
    • Lee, E.Y.1    Chang, C.Y.2    Hu, N.3    Wang, Y.C.4    Lai, C.C.5    Herrup, K.6    Lee, W.H.7    Bradley, A.8
  • 124
    • 0033624014 scopus 로고    scopus 로고
    • C/EBPα inhibits cell growth via direct repression of E2F-DP-mediated transcription
    • Slomiany B.A., D'Arigo K.L., Kelly M.M., Kurtz D.T. C/EBPα inhibits cell growth via direct repression of E2F-DP-mediated transcription. Mol. Cell. Biol. 20:2000;5986-5997.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5986-5997
    • Slomiany, B.A.1    D'Arigo, K.L.2    Kelly, M.M.3    Kurtz, D.T.4
  • 126
    • 0033568578 scopus 로고    scopus 로고
    • Involvement of the retinoblastoma protein in monocytic and neutrophilic lineage commitment of human bone marrow progenitor cells
    • Bergh G., Ehinger M., Olsson I., Jacobsen S.E., Gullberg U. Involvement of the retinoblastoma protein in monocytic and neutrophilic lineage commitment of human bone marrow progenitor cells. Blood. 94:1999;1971-1978.
    • (1999) Blood , vol.94 , pp. 1971-1978
    • Bergh, G.1    Ehinger, M.2    Olsson, I.3    Jacobsen, S.E.4    Gullberg, U.5
  • 127
    • 0033523881 scopus 로고    scopus 로고
    • Granulocytic differentiation of myeloid progenitor cells by p130, the retinoblastoma tumour suppressor homologue
    • Mori A., Higashi H., Hoshikawa Y., Imamura M., Asaka M., Hatakeyama M. Granulocytic differentiation of myeloid progenitor cells by p130, the retinoblastoma tumour suppressor homologue. Oncogene. 18:1999;6209-6221.
    • (1999) Oncogene , vol.18 , pp. 6209-6221
    • Mori, A.1    Higashi, H.2    Hoshikawa, Y.3    Imamura, M.4    Asaka, M.5    Hatakeyama, M.6
  • 129


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