Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: A new series of selective COX-2 inhibitors

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 7, 2003, Pages 1153-1160

  Hu, Wenhui ^a   Guo, Zongru ^a   Chu, Fengming ^a   Bai, Aiping ^a   Yi, Xiang ^a   Cheng, Guifang ^b   Li, Jing ^b  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 AMINOSULFONYLPHENYL) 3 (2 CHLOROPHENYL) 5 CHLOROINDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (3 CHLOROPHENYL) 5 CHLOROINDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (3,4 DIMETHYLPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (4 BROMOPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (4 CHLOROPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (4 FLUOROPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (4 HYDROXYPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (4 METHOXYPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 (4 METHYLPHENYL)INDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 PHENYL 5 CHLOROINDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 PHENYL 5 FLUOROINDOLE; 2 (4 AMINOSULFONYLPHENYL) 3 PHENYLINDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (2 CHLOROPHENYL) 5 CHLOROINDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (3 CHLOROPHENYL) 5 CHLOROINDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (3,4 DIMETHYLPHENYL)INDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (4 CHLOROPHENYL) 5 CHLOROINDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (4 CHLOROPHENYL)INDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (4 FLUOROPHENYL)INDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (4 METHOXYPHENYL)INDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 (4 METHYLPHENYL)INDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 PHENYL 5 CHLOROINDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 PHENYL 5 METHYLINDOLE; 2 (4 METHYLSULFONYLPHENYL) 3 PHENYLINDOLE; 2 (N ACETAMIDE SULFONYLPHENYL) 3 PHENYLINDOLE; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN;

EID: 0037375844     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00046-4     Document Type: Article

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