Synthesis and biological evaluation of 5,6-diarylimidazo[2.1-b]thiazole as selective COX-2 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 1, 1997, Pages 47-52

  Thérien, Michel ^a   Brideau, Christine ^a   Chan, Chi Chung ^a   Cromlish, Wanda A ^a   Gauthier, Jacques Yves ^a   Gordon, Robert ^a   Greig, Gillian ^a   Kargman, Stacia ^a   Lau, Cheuk Kun ^a   Leblanc, Yves ^a   Li, Chun Sing ^a   O'Neill, Gary P ^a   Riendeau, Denis ^a   Roy, Patrick ^a   Wang, Zhaoyin ^a   Xu, Lijing ^a   Prasit, Petpiboon ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 METHYLSULFONYLPHENYL) 6 PHENYLIMIDAZO[2,1 B]THIAZOLE; 5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; IMIDAZO[2,1 B]THIAZOLE DERIVATIVE; ISOENZYME; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; NONHUMAN; REACTION ANALYSIS;

EID: 0343052956     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00580-X     Document Type: Article

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