4-[5-Methyl-3-phenylisoxazol-4-yl]-benzenesulfonamide, Valdecoxib: A potent and selective inhibitor of COX-2 [4]

Journal of Medicinal Chemistry

Volumn 43, Issue 5, 2000, Pages 775-777

  Talley, John J ^a   Brown, David L ^a   Carter, Jeffery S ^a   Graneto, Matthew J ^a   Koboldt, Carol M ^a   Masferrer, Jaime L ^a   Perkins, William E ^a   Rogers, Roland S ^a   Shaffer, Alexander F ^a   Zhang, Yan Y ^a   Zweifel, Ben S ^a   Seibert, Karen ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG; VALDECOXIB;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; LETTER; NONHUMAN; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; CYCLOOXYGENASE 2; EDEMA; ENZYME INHIBITORS; HUMANS; ISOENZYMES; ISOXAZOLES; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RECOMBINANT PROTEINS; SULFONAMIDES;

EID: 0034624748     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990577v     Document Type: Letter

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