-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr, J. F., Wyllie, A. H. & Currie, A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257 (1972).
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
2
-
-
0034641980
-
Apoptosis in development
-
Meier, P., Finch, A. & Evan, G. I. Apoptosis in development. Nature 407, 796-801 (2000).
-
(2000)
Nature
, vol.407
, pp. 796-801
-
-
Meier, P.1
Finch, A.2
Evan, G.I.3
-
3
-
-
0035937420
-
Cell death inhibition: Keeping caspases in check
-
Goyal, L. Cell death inhibition: keeping caspases in check. Cell 104, 805-808 (2001).
-
(2001)
Cell
, vol.104
, pp. 805-808
-
-
Goyal, L.1
-
4
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer, P. H. CD95's deadly mission in the immune system. Nature 407, 789-795 (2000).
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
5
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang, X. The expanding role of mitochondria in apoptosis. Genes Dev. 15, 2922-2933 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
6
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P. et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489 (1997).
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
-
7
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du, C., Fang, M., Li, Y., Li, L. & Wang, X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102, 33-42 (2000).
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
8
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory, S. & Adams, J. M. The Bcl2 family: regulators of the cellular life-or-death switch. Nature Rev. Cancer 2, 647-656 (2002).
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
9
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong, W. X., Lindsten, T., Ross, A. J., MacGregor, G. R. & Thompson, C. B. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15, 1481-1486 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
11
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi, Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell 9, 459-470 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
12
-
-
0035854738
-
X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-β signaling
-
Birkey Reffey, S., Wurthner, J. U., Parks, W. T., Roberts, A. B. & Duckett, C. S. X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-β signaling. J. Biol. Chem. 276, 26542-26549 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26542-26549
-
-
Birkey Reffey, S.1
Wurthner, J.U.2
Parks, W.T.3
Roberts, A.B.4
Duckett, C.S.5
-
13
-
-
0036178047
-
IAP suppression of apoptosis involves distinct mechanisms: The TAK1/JNK1 signaling cascade and caspase inhibition
-
Sanna, M. G. et al. IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition. Mol. Cell. Biol. 22, 1754-1766 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1754-1766
-
-
Sanna, M.G.1
-
14
-
-
0033621107
-
Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division
-
Uren, A. G. et al. Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division. Proc. Natl Acad. Sci. USA 96, 10170-10175 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10170-10175
-
-
Uren, A.G.1
-
15
-
-
0034629466
-
Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast
-
Li, F., Flanary, P. L., Altieri, D. C. & Dohlman, H. G. Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J. Biol. Chem. 275, 6707-6711 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6707-6711
-
-
Li, F.1
Flanary, P.L.2
Altieri, D.C.3
Dohlman, H.G.4
-
16
-
-
0034820448
-
Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair
-
Morishita, J. et al. Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair. Genes Cells 6, 743-763 (2001).
-
(2001)
Genes Cells
, vol.6
, pp. 743-763
-
-
Morishita, J.1
-
17
-
-
0033637849
-
The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone
-
Speliotes, E. K., Uren, A., Vaux, D. & Horvitz, H. R. The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone. Mol. Cell 6, 211-223 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 211-223
-
-
Speliotes, E.K.1
Uren, A.2
Vaux, D.3
Horvitz, H.R.4
-
18
-
-
0033602489
-
Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis
-
Fraser, A. G., James, C., Evan, G. I. & Hengartner, M. O. Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis. Curr. Biol. 9, 292-301 (1999). First demonstration that ablation of an IAP gene in the nematode results in lethal defects of cell division without affecting programmed cell death.
-
(1999)
Curr. Biol.
, vol.9
, pp. 292-301
-
-
Fraser, A.G.1
James, C.2
Evan, G.I.3
Hengartner, M.O.4
-
19
-
-
0035037802
-
Characterization of XIAP-deficient mice
-
Harlin, H., Reffey, S. B., Duckett, C. S., Lindsten, T. & Thompson, C. B. Characterization of XIAP-deficient mice. Mol. Cell. Biol. 21, 3604-3608 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3604-3608
-
-
Harlin, H.1
Reffey, S.B.2
Duckett, C.S.3
Lindsten, T.4
Thompson, C.B.5
-
20
-
-
0034282432
-
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang, H. et al. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J. Biol. Chem. 275, 26661-26664 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
-
21
-
-
0034607655
-
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
-
Yang, Y., Fang, S., Jensen, J. P. Weissman, A. M. & Ashwell, J. D. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 288, 874-877 (2000).
-
(2000)
Science
, vol.288
, pp. 874-877
-
-
Yang, Y.1
Fang, S.2
Jensen, J.P.3
Weissman, A.M.4
Ashwell, J.D.5
-
22
-
-
0037188903
-
Destabilizing influences in apoptosis: Sowing the seeds of IAP destruction
-
Martin, S. J. Destabilizing influences in apoptosis: sowing the seeds of IAP destruction. Cell 109, 807-809 (2002).
-
(2002)
Cell
, vol.109
, pp. 807-809
-
-
Martin, S.J.1
-
23
-
-
0035902601
-
Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death
-
Suzuki, Y., Nakabayashi, Y. & Takahashi, R. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc. Natl Acad. Sci. USA 98, 8662-8667 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
24
-
-
0030746636
-
A novel antiapoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini, G., Adida, C. & Altieri, D. C. A novel antiapoptosis gene, survivin, expressed in cancer and lymphoma. Nature Med. 3, 917-921 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
25
-
-
0032506524
-
Control of apoptosis and mitotic spindle checkpoint by survivin
-
Li, F. et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396, 580-584 (1998). Demonstration that survivin interfaces between the microtubule control of cell division and the preservation of an anti-apoptotic environment in dividing cells.
-
(1998)
Nature
, vol.396
, pp. 580-584
-
-
Li, F.1
-
26
-
-
0033168929
-
The cancer antiapoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression
-
Li, F. & Altieri, D. C. The cancer antiapoptosis mouse survivin gene: characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression. Cancer Res. 59, 3143-3151 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 3143-3151
-
-
Li, F.1
Altieri, D.C.2
-
27
-
-
0033571983
-
Survivin-ΔEx3 and survivin-2B: Two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties
-
Mahotka, C., Wenzel, M., Springer, E., Gabbert, H. E. & Gerharz, C. D. Survivin-ΔEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties. Cancer Res. 59, 6097-6102 (1999). Identification of two alternatively spliced forms of survivin that are potentially divergent from the wild-type protein for subcellular localization and the ability to counteract apoptosis.
-
(1999)
Cancer Res.
, vol.59
, pp. 6097-6102
-
-
Mahotka, C.1
Wenzel, M.2
Springer, E.3
Gabbert, H.E.4
Gerharz, C.D.5
-
28
-
-
0036343736
-
CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin
-
Rodriguez, J. A., Span, S. W., Ferreira, C. G., Kruyt, F. A. & Giaccone, G. CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin. Exp. Cell Res. 275, 44-53 (2002).
-
(2002)
Exp. Cell Res.
, vol.275
, pp. 44-53
-
-
Rodriguez, J.A.1
Span, S.W.2
Ferreira, C.G.3
Kruyt, F.A.4
Giaccone, G.5
-
29
-
-
0037013894
-
Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
-
Wang, H. W., Sharp, T. V., Koumi, A., Koentges, G. & Boshoff, C. Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin. EMBO J. 21, 2602-2615 (2002). A new twist in the survivin cytoprotection pathway: localization of a herpes simplex virus homologue of alternatively spliced survivin-AEx3 to mitochondria and physical interaction with caspase-3.
-
(2002)
EMBO J.
, vol.21
, pp. 2602-2615
-
-
Wang, H.W.1
Sharp, T.V.2
Koumi, A.3
Koentges, G.4
Boshoff, C.5
-
30
-
-
0033923368
-
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
-
Verdecia, M. A. et al. Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement. Nature Struct. Biol. 7, 602-608 (2000).
-
(2000)
Nature Struct. Biol.
, vol.7
, pp. 602-608
-
-
Verdecia, M.A.1
-
31
-
-
0033635270
-
Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions
-
Chantalat, L. et al. Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions. Mol. Cell 6, 183-189 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 183-189
-
-
Chantalat, L.1
-
32
-
-
0033635269
-
Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin
-
Muchmore, S. W. et al. Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin. Mol. Cell 6, 173-182 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 173-182
-
-
Muchmore, S.W.1
-
33
-
-
0034019111
-
Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells
-
Badie, C., Itzhaki, J. E., Sullivan, M. J., Carpenter, A. J. & Porter, A. C. Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells. Mol. Cell. Biol. 20, 2358-2366 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2358-2366
-
-
Badie, C.1
Itzhaki, J.E.2
Sullivan, M.J.3
Carpenter, A.J.4
Porter, A.C.5
-
34
-
-
0033573905
-
Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation
-
Kobayashi, K., Hatano, M., Otaki, M., Ogasawara, T. & Tokuhisa, T. Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc. Natl Acad. Sci. USA 96, 1457-1462 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1457-1462
-
-
Kobayashi, K.1
Hatano, M.2
Otaki, M.3
Ogasawara, T.4
Tokuhisa, T.5
-
35
-
-
0033436285
-
Transcriptional analysis of human survivin gene expression
-
Li, F. & Altieri, D. C. Transcriptional analysis of human survivin gene expression. Biochem. J. 344, 305-311 (1999).
-
(1999)
Biochem. J.
, vol.344
, pp. 305-311
-
-
Li, F.1
Altieri, D.C.2
-
36
-
-
0034532701
-
The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner
-
Zhao, J., Tenev, T., Martins, L. M., Downward, J. & Lemoine, N. R. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner. J. Cell Sci. 113, 4363-4371 (2000).
-
(2000)
J. Cell Sci.
, vol.113
, pp. 4363-4371
-
-
Zhao, J.1
Tenev, T.2
Martins, L.M.3
Downward, J.4
Lemoine, N.R.5
-
37
-
-
0036655052
-
A p34(cdc2) survival checkpoint in cancer
-
O'Connor, D. S., Wall, N. R., Porter, A. C. & Altieri, D. C. A p34(cdc2) survival checkpoint in cancer. Cancer Cell 2, 43-54 (2002). Rational targeting of survivin to maximize the antitumour effect of taxane-based chemotherapy in cancer treatment.
-
(2002)
Cancer Cell
, vol.2
, pp. 43-54
-
-
O'Connor, D.S.1
Wall, N.R.2
Porter, A.C.3
Altieri, D.C.4
-
38
-
-
0033258543
-
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
-
Li, F. et al. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nature Cell Biol. 1, 461-466 (1999).
-
(1999)
Nature Cell Biol.
, vol.1
, pp. 461-466
-
-
Li, F.1
-
39
-
-
0034822324
-
Participation of Survivin in mitotic and apoptotic activities of normal and tumor-derived cells
-
Jiang, X. et al. Participation of Survivin in mitotic and apoptotic activities of normal and tumor-derived cells. J. Cell Biochem. 83, 342-354 (2001).
-
(2001)
J. Cell Biochem.
, vol.83
, pp. 342-354
-
-
Jiang, X.1
-
40
-
-
0034739857
-
Human survivin is a kinetochore-associated passenger protein
-
Skoufias, D. A., Mollinari, C., Lacroix, F. B. & Margolis, R. L. Human survivin is a kinetochore-associated passenger protein. J. Cell Biol. 151, 1575-1582 (2000).
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1575-1582
-
-
Skoufias, D.A.1
Mollinari, C.2
Lacroix, F.B.3
Margolis, R.L.4
-
41
-
-
0036472994
-
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function
-
Fortugno, P. et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J. Cell Sci. 115, 575-585 (2002). Reconciles earlier discrepant findings on the subcellular localization of survivin to multiple compartments of the mitotic apparatus.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 575-585
-
-
Fortugno, P.1
-
42
-
-
0035810919
-
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis
-
Wheatley, S. P., Carvalho, A., Vagnarelli, P. & Earnshaw, W. C. INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis. Curr. Biol. 11, 886-890 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 886-890
-
-
Wheatley, S.P.1
Carvalho, A.2
Vagnarelli, P.3
Earnshaw, W.C.4
-
43
-
-
0034597594
-
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
-
Uren, A. G. et al. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr. Biol. 10, 1319-1328 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1319-1328
-
-
Uren, A.G.1
-
44
-
-
0035496913
-
Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: Implication of survivin expression in normal hematopoiesis
-
Fukuda, S. & Pelus, L. M. Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis. Blood 98, 2091-2100 (2001).
-
(2001)
Blood
, vol.98
, pp. 2091-2100
-
-
Fukuda, S.1
Pelus, L.M.2
-
45
-
-
0036785405
-
The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34(+) cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells
-
Fukuda, S., Foster, R. G., Porter, S. B. & Pelus, L. M. The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34(+) cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells. Blood 100, 2463-2471 (2002). Demonstration that survivin gene expression can occur independently of mitotic progression in interphase bone-marrow progenitor cells.
-
(2002)
Blood
, vol.100
, pp. 2463-2471
-
-
Fukuda, S.1
Foster, R.G.2
Porter, S.B.3
Pelus, L.M.4
-
46
-
-
0035076453
-
Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway
-
Mahboubi, K. et al. Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway. Lab. Invest. 81, 327-334 (2001).
-
(2001)
Lab. Invest.
, vol.81
, pp. 327-334
-
-
Mahboubi, K.1
-
47
-
-
0034737422
-
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
-
Papapetropoulos, A. et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J. Biol. Chem. 275, 9102-9105 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9102-9105
-
-
Papapetropoulos, A.1
-
48
-
-
0142237285
-
Inhibition of STAT3 signaling induces apoptosis and decreases Survivin expression in primary effusion lymphoma
-
3 Oct, [epub ahead of print]
-
Aoki, Y., Feldman, G. M. & Tosato, G. Inhibition of STAT3 signaling induces apoptosis and decreases Survivin expression in primary effusion lymphoma. Blood 3 Oct 2002 [epub ahead of print].
-
(2002)
Blood
-
-
Aoki, Y.1
Feldman, G.M.2
Tosato, G.3
-
49
-
-
0034993758
-
Two kinds of BIR-containing protein-inhibitors of apoptosis, or required for mitosis
-
Silke, J. & Vaux, D. L. Two kinds of BIR-containing protein-inhibitors of apoptosis, or required for mitosis. J. Cell Sci. 114, 1821-1827 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1821-1827
-
-
Silke, J.1
Vaux, D.L.2
-
50
-
-
0035252654
-
Chromosomal passengers and the (aurora) ABCs of mitosis
-
Adams, R. R., Carmena, M. & Earnshaw, W. C. Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol. 11, 49-54 (2001).
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 49-54
-
-
Adams, R.R.1
Carmena, M.2
Earnshaw, W.C.3
-
51
-
-
0032403126
-
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
-
Tamm, I. et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58, 5315-5320 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 5315-5320
-
-
Tamm, I.1
-
52
-
-
0034594915
-
Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death
-
Suzuki, A. et al. Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death. Oncogene 19, 1346-1353 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 1346-1353
-
-
Suzuki, A.1
-
53
-
-
0034598797
-
High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma
-
Islam, A. et al. High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma. Oncogene 19, 617-623 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 617-623
-
-
Islam, A.1
-
54
-
-
0035793557
-
Livin, a novel inhibitor-of-apoptosis (IAP) family member
-
Kasof, G. M. & Gomes, B. C. Livin, a novel inhibitor-of-apoptosis (IAP) family member. J. Biol. Chem. 276, 3238-3246 (2000).
-
(2000)
J. Biol. Chem.
, vol.276
, pp. 3238-3246
-
-
Kasof, G.M.1
Gomes, B.C.2
-
55
-
-
18344369169
-
Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway
-
Mirza, A. et al. Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway. Oncogene 21, 2613-2622 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 2613-2622
-
-
Mirza, A.1
-
56
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
Hoffman, W. H., Biade, S., Zilfou, J. T., Chen, J. & Murphy, M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J. Biol. Chem. 277, 3247-3257 (2001). A potential molecular basis for the widespread differential expression of survivin in embryologically disparate tumours following loss of wild-type p53.
-
(2001)
J. Biol. Chem.
, vol.277
, pp. 3247-3257
-
-
Hoffman, W.H.1
Biade, S.2
Zilfou, J.T.3
Chen, J.4
Murphy, M.5
-
57
-
-
0036693488
-
Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer
-
Zaffaroni, N. et al. Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer. Cell Mol. Life Sci. 59, 1406-1412 (2002).
-
(2002)
Cell Mol. Life Sci.
, vol.59
, pp. 1406-1412
-
-
Zaffaroni, N.1
-
58
-
-
0034795822
-
Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53
-
Grossman, D. et al. Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J. Clin. Invest. 108, 991-999 (2001). A functional link between survivin and loss of p53 in ablating apoptosis in a transgenic mouse model.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 991-999
-
-
Grossman, D.1
-
59
-
-
0036320354
-
Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways
-
Conway, E. M. et al. Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways. Gastroenterology 123, 619-631 (2002).
-
(2002)
Gastroenterology
, vol.123
, pp. 619-631
-
-
Conway, E.M.1
-
60
-
-
0036773347
-
Overexpression of TIAP/m-survivin in thymocytes enhances cell proliferation
-
Hikita, S. et al. Overexpression of TIAP/m-survivin in thymocytes enhances cell proliferation. Mol. Immunol. 39, 289-298 (2002).
-
(2002)
Mol. Immunol.
, vol.39
, pp. 289-298
-
-
Hikita, S.1
-
61
-
-
0032080335
-
Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting
-
Ambrosini, G., Adida, C., Sirugo, G. & Altieri, D. C. Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting. J. Biol. Chem. 273, 11177-11182 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11177-11182
-
-
Ambrosini, G.1
Adida, C.2
Sirugo, G.3
Altieri, D.C.4
-
62
-
-
0033397882
-
Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma
-
Grossman, D., McNiff, J. M., Li, F. & Altieri, D. C. Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma. Invest. Dermatol. 113, 1076-1081 (1999).
-
(1999)
Invest. Dermatol.
, vol.113
, pp. 1076-1081
-
-
Grossman, D.1
McNiff, J.M.2
Li, F.3
Altieri, D.C.4
-
63
-
-
9144247196
-
Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth
-
Chen, J. et al. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia 2, 235-241 (2000).
-
(2000)
Neoplasia
, vol.2
, pp. 235-241
-
-
Chen, J.1
-
64
-
-
0342657718
-
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
-
Olie, R. A. et al. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res. 60, 2805-2809 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 2805-2809
-
-
Olie, R.A.1
-
65
-
-
0034779647
-
Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways
-
Shankar, S. L. et al. Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways. J. Neurochem. 79, 426-436 (2001).
-
(2001)
J. Neurochem.
, vol.79
, pp. 426-436
-
-
Shankar, S.L.1
-
66
-
-
0035904376
-
Effects of survivin antagonists on growth of established tumors and b7-1 immunogene therapy
-
Kanwar, J. R., Shen, W. P., Kanwar, R. K., Berg, R. W. & Krissansen, G. W. Effects of survivin antagonists on growth of established tumors and b7-1 immunogene therapy. J. Natl Cancer Inst. 93, 1541-1552 (2001). Establishes proof of concept that targeting survivin in vivo cooperates with anticancer regimens and facilitates tumour eradication.
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 1541-1552
-
-
Kanwar, J.R.1
Shen, W.P.2
Kanwar, R.K.3
Berg, R.W.4
Krissansen, G.W.5
-
67
-
-
0036155862
-
Ribozyme-mediated attenuation of survivin expression sensitizes human melanoma cells to cisplatin-induced apoptosis
-
Pennati, M. et al. Ribozyme-mediated attenuation of survivin expression sensitizes human melanoma cells to cisplatin-induced apoptosis. J. Clin. Invest. 109, 285-286 (2002).
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 285-286
-
-
Pennati, M.1
-
68
-
-
0036785525
-
DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells
-
Zhou, M. et al. DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells. J. Pharmacol. Exp. Ther. 303, 124-131 (2002).
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.303
, pp. 124-131
-
-
Zhou, M.1
-
69
-
-
0034698097
-
Deterin, a new inhibitor of apoptosis from Drosophila melanogaster
-
Jones, G., Jones, D., Zhou, L., Steller, H. & Chu, Y. Deterin, a new inhibitor of apoptosis from Drosophila melanogaster. J. Biol. Chem. 275, 22157-22165 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22157-22165
-
-
Jones, G.1
Jones, D.2
Zhou, L.3
Steller, H.4
Chu, Y.5
-
70
-
-
0034651927
-
Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions
-
Conway, E. M. et al. Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions. Blood 95, 1435-1442 (2000).
-
(2000)
Blood
, vol.95
, pp. 1435-1442
-
-
Conway, E.M.1
-
71
-
-
0035969963
-
An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7
-
Shin, S. et al. An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7. Biochemistry 40, 1117-1123 (2001).
-
(2001)
Biochemistry
, vol.40
, pp. 1117-1123
-
-
Shin, S.1
-
73
-
-
0034789355
-
Cancer gene therapy using a survivin mutant adenovirus
-
Mesri, M., Wall, N. R., Li, J., Kim, R. W. & Altieri, D. C. Cancer gene therapy using a survivin mutant adenovirus. J. Clin. Invest. 108, 981-990 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 981-990
-
-
Mesri, M.1
Wall, N.R.2
Li, J.3
Kim, R.W.4
Altieri, D.C.5
-
74
-
-
0035650709
-
Human inhibitor of apoptosis protein (IAP) survivin participates in regulation of chromosome segregation and mitotic exit
-
Kallio, M. J., Nieminen, M. & Eriksson, J. E. Human inhibitor of apoptosis protein (IAP) survivin participates in regulation of chromosome segregation and mitotic exit. FASEB J. 15, 2721-2723 (2001).
-
(2001)
FASEB J.
, vol.15
, pp. 2721-2723
-
-
Kallio, M.J.1
Nieminen, M.2
Eriksson, J.E.3
-
75
-
-
0036732808
-
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation
-
Bolton, M. A. et al. Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol. Biol. Cell 13, 3064-3077 (2002). A survivin homologue in Xenopus laevis controls the enzymatic activity of Aurora kinase, a multifunctional regulator of mitosis.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3064-3077
-
-
Bolton, M.A.1
-
76
-
-
0036570207
-
Regulation of microtubule stability and mitotic progression by survivin
-
Giodini, A. et al. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res. 62, 2462-2467 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 2462-2467
-
-
Giodini, A.1
-
77
-
-
0037007037
-
A role for survivin in chemoresistance of endothelial cells mediated by VEGF
-
Tran, J. et al. A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proc. Natl Acad. Sci. USA 99, 4349-4354 (2002). Demonstration that survivin can reduce the effectiveness of anti-angiogenic therapy in cancer treatment.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4349-4354
-
-
Tran, J.1
-
78
-
-
0031984247
-
Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation
-
Adida, C. et al. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am. J. Pathol. 152, 43-49 (1998).
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 43-49
-
-
Adida, C.1
-
79
-
-
0035353163
-
Cytokine-regulated expression of survivin in myeloid leukemia
-
Carter, B. Z., Milella, M., Altieri, D. C. & Andreeff, M. Cytokine-regulated expression of survivin in myeloid leukemia. Blood 97, 2784-2790 (2001).
-
(2001)
Blood
, vol.97
, pp. 2784-2790
-
-
Carter, B.Z.1
Milella, M.2
Altieri, D.C.3
Andreeff, M.4
-
80
-
-
0035126561
-
Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa
-
Gianani, R. et al. Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa. Hum. Pathol. 32, 119-125 (2001).
-
(2001)
Hum. Pathol.
, vol.32
, pp. 119-125
-
-
Gianani, R.1
-
81
-
-
0035893568
-
Evidence that APC regulates survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer
-
Zhang, T. et al. Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res. 61, 8664-8667 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 8664-8667
-
-
Zhang, T.1
-
82
-
-
0032986544
-
A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers
-
Monzo, M. et al. A novel anti-apoptosis gene: re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers. J. Clin. Oncol. 17, 2100-2104 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2100-2104
-
-
Monzo, M.1
-
83
-
-
0033980409
-
Expression of survivin and its relationship to loss of apoptosis in breast carcinomas
-
Tanaka, K. et al. Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin. Cancer Res. 6, 127-134 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 127-134
-
-
Tanaka, K.1
-
84
-
-
0032533494
-
Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer
-
Kawasaki, H. et al. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 58, 5071-5074 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 5071-5074
-
-
Kawasaki, H.1
-
85
-
-
0032080378
-
Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas
-
Lu, C. D., Altieri, D. C. & Tanigawa, N. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res. 58, 1808-1812 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 1808-1812
-
-
Lu, C.D.1
Altieri, D.C.2
Tanigawa, N.3
-
86
-
-
0035916997
-
Expression of survivin in esophageal cancer: Correlation with the prognosis and response to chemotherapy
-
Kato, J. et al. Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy. Int. J. Cancer 95, 92-95 (2001).
-
(2001)
Int. J. Cancer
, vol.95
, pp. 92-95
-
-
Kato, J.1
-
87
-
-
0035878930
-
Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors
-
Satoh, K. et al. Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors. Cancer 92, 271-278 (2001).
-
(2001)
Cancer
, vol.92
, pp. 271-278
-
-
Satoh, K.1
-
88
-
-
0036793871
-
Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma
-
Ikeguchi, M., Ueta, T., Yamane, Y., Hirooka, Y. & Kaibara, N. Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma. Clin. Cancer Res. 8, 3131-3136 (2002).
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3131-3136
-
-
Ikeguchi, M.1
Ueta, T.2
Yamane, Y.3
Hirooka, Y.4
Kaibara, N.5
-
89
-
-
0033158714
-
Analysis of Bcl-2, Bax and Survivin genes in uterine cancer
-
Saitoh, Y., Yaginuma, Y. & Ishikawa, M. Analysis of Bcl-2, Bax and Survivin genes in uterine cancer. Int. J. Oncol. 15, 137-141 (1999).
-
(1999)
Int. J. Oncol.
, vol.15
, pp. 137-141
-
-
Saitoh, Y.1
Yaginuma, Y.2
Ishikawa, M.3
-
90
-
-
0035464197
-
Survivin, Bcl-2 and matrix metalloproteinase-2 enhance progression of clear cell- and serous-type ovanan carcinomas
-
Yoshida, H., Ishiko, O., Sumi, T., Matsumoto, Y. & Ogita, S. Survivin, Bcl-2 and matrix metalloproteinase-2 enhance progression of clear cell- and serous-type ovanan carcinomas. Int. J. Oncol. 19, 537-542 (2001).
-
(2001)
Int. J. Oncol.
, vol.19
, pp. 537-542
-
-
Yoshida, H.1
Ishiko, O.2
Sumi, T.3
Matsumoto, Y.4
Ogita, S.5
-
91
-
-
0037665014
-
Hodgkin's and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: Analyses using tissue-microarrays
-
12 Sept, [epub ahead of print]
-
Garcia, J. F. et al. Hodgkin's and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: analyses using tissue-microarrays. Blood 12 Sept 2002 [epub ahead of print].
-
(2002)
Blood
-
-
Garcia, J.F.1
-
92
-
-
0034284050
-
Prognostic significance of survivin expression in diffuse large B-cell lymphomas
-
Adida, C. et al. Prognostic significance of survivin expression in diffuse large B-cell lymphomas. Blood 96, 1921-1925 (2000).
-
(2000)
Blood
, vol.96
, pp. 1921-1925
-
-
Adida, C.1
-
93
-
-
85014269563
-
Relationship between expression of genes involved in cell cycle control and apoptosis in diffuse large B cell lymphoma: A preferential survivin-cyclin B link
-
Kuttler, F. et al. Relationship between expression of genes involved in cell cycle control and apoptosis in diffuse large B cell lymphoma: a preferential survivin-cyclin B link. Leukemia 16, 726-735 (2002).
-
(2002)
Leukemia
, vol.16
, pp. 726-735
-
-
Kuttler, F.1
-
94
-
-
0033768666
-
Expression and prognostic significance of survivin in de novo acute myeloid leukaemia
-
Adida, C. et al. Expression and prognostic significance of survivin in de novo acute myeloid leukaemia. Br. J. Haematol. 111, 196-203 (2000).
-
(2000)
Br. J. Haematol.
, vol.111
, pp. 196-203
-
-
Adida, C.1
-
95
-
-
0034933717
-
Aberrant expression of caspase cascade regulatory genes in adult T-cell leukaemia: Survivin is an important determinant for prognosis
-
Kamihira, S. et al. Aberrant expression of caspase cascade regulatory genes in adult T-cell leukaemia: survivin is an important determinant for prognosis. Br. J. Haematol. 114, 63-69 (2001).
-
(2001)
Br. J. Haematol.
, vol.114
, pp. 63-69
-
-
Kamihira, S.1
-
96
-
-
0032554527
-
Anti-apoptosis gene, survivin, and prognosis of neuroblastoma
-
Adida, C., Berrebi, D., Peuchmaur, M., Reyes-Mugica, M. & Altieri, D. C. Anti-apoptosis gene, survivin, and prognosis of neuroblastoma. Lancet 351, 882-883 (1998).
-
(1998)
Lancet
, vol.351
, pp. 882-883
-
-
Adida, C.1
Berrebi, D.2
Peuchmaur, M.3
Reyes-Mugica, M.4
Altieri, D.C.5
-
97
-
-
0036207949
-
Survivin: A novel neuroendocrine marker for pheochromocytoma
-
Koch, C. A. et al. Survivin: a novel neuroendocrine marker for pheochromocytoma. Eur. J. Endocrinol. 146, 381-388 (2002).
-
(2002)
Eur. J. Endocrinol.
, vol.146
, pp. 381-388
-
-
Koch, C.A.1
-
98
-
-
0037117121
-
Co-expression of survivin and TERT and risk of tumour-related death in patients with soft-tissue sarcoma
-
Wurl, P. et al. Co-expression of survivin and TERT and risk of tumour-related death in patients with soft-tissue sarcoma. Lancet 359, 943-945 (2002).
-
(2002)
Lancet
, vol.359
, pp. 943-945
-
-
Wurl, P.1
-
99
-
-
0037083317
-
Quantitatively determined survivin expression levels are of prognostic value in human gliomas
-
Chakravarti, A. et al. Quantitatively determined survivin expression levels are of prognostic value in human gliomas. J. Clin. Oncol. 20, 1063-1068 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1063-1068
-
-
Chakravarti, A.1
-
100
-
-
0036281671
-
An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin
-
Hirohashi, Y. et al. An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin. Clin. Cancer Res. 8, 1731-1739 (2002).
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1731-1739
-
-
Hirohashi, Y.1
-
101
-
-
0037012343
-
Activation of cancer-specific gene expression by the survivin promoter
-
Bao, R. et al. Activation of cancer-specific gene expression by the survivin promoter. J. Natl Cancer Inst. 94, 522-528 (2002). Strong evidence that the differential expression of survivin in cancer versus normal tissues is largely controlled at the level of gene transcription.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 522-528
-
-
Bao, R.1
-
102
-
-
0035964487
-
DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes
-
Hattori, M., Sakamoto, H., Satoh, K. & Yamamoto, T. DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes. Cancer Lett. 169, 155-164 (2001).
-
(2001)
Cancer Lett.
, vol.169
, pp. 155-164
-
-
Hattori, M.1
Sakamoto, H.2
Satoh, K.3
Yamamoto, T.4
-
103
-
-
20244376287
-
Increased survivin transcript levels: An independent negative predictor of survival in soft tissue sarcoma patients
-
Kappler, M. et al. Increased survivin transcript levels: an independent negative predictor of survival in soft tissue sarcoma patients. Int. J. Cancer 95, 360-363 (2001).
-
(2001)
Int. J. Cancer
, vol.95
, pp. 360-363
-
-
Kappler, M.1
-
104
-
-
0034021068
-
Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma
-
Sarela, A. I., Macadam, R. C., Farmery, S. M., Markham, A. F. & Guillou, P. J. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. Gut 46, 645-650 (2000).
-
(2000)
Gut
, vol.46
, pp. 645-650
-
-
Sarela, A.I.1
Macadam, R.C.2
Farmery, S.M.3
Markham, A.F.4
Guillou, P.J.5
-
105
-
-
0037037331
-
Survivin messenger RNA expression is a good prognostic biomarker for oesophageal carcinoma
-
Ikeguchi, M. & Kaibara, N. Survivin messenger RNA expression is a good prognostic biomarker for oesophageal carcinoma. Br. J. Cancer 87, 883-887 (2002).
-
(2002)
Br. J. Cancer
, vol.87
, pp. 883-887
-
-
Ikeguchi, M.1
Kaibara, N.2
-
106
-
-
0033527054
-
Tumor content of the antiapoptosis molecule survivin and recurrence of bladder cancer
-
Swana, H. S., Grossman, D., Anthony, J. N., Weiss, R. M. & Altieri, D. C. Tumor content of the antiapoptosis molecule survivin and recurrence of bladder cancer. N. Engl. J. Med. 341, 452-453 (1999).
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 452-453
-
-
Swana, H.S.1
Grossman, D.2
Anthony, J.N.3
Weiss, R.M.4
Altieri, D.C.5
-
107
-
-
0036105153
-
Survivin: A universal tumor antigen
-
Andersen, M. H. & thor, S. P. Survivin: a universal tumor antigen. Histol. Histopathol. 17, 669-675 (2002).
-
(2002)
Histol. Histopathol.
, vol.17
, pp. 669-675
-
-
Andersen, M.H.1
Thor, S.P.2
-
108
-
-
0034074562
-
Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients
-
Rohayem, J. et al. Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients. Cancer Res. 60, 1815-1817 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 1815-1817
-
-
Rohayem, J.1
-
109
-
-
0034859470
-
Detection of anti-survivin antibody in gastrointestinal cancer patients
-
Yagihashi, A. et al. Detection of anti-survivin antibody in gastrointestinal cancer patients. Clin. Chem. 47, 1729-1731 (2001).
-
(2001)
Clin. Chem.
, vol.47
, pp. 1729-1731
-
-
Yagihashi, A.1
-
110
-
-
0034282551
-
+ T effector cells by dendritic cells pulsed with protein or selected peptides
-
+ T effector cells by dendritic cells pulsed with protein or selected peptides. Cancer Res. 60, 4845-4849 (2000). First demonstration that survivin can elicit a tumour-specific immune response of potential therapeutic significance for cancer vaccination strategies.
-
(2000)
Cancer Res.
, vol.60
, pp. 4845-4849
-
-
Schmitz, M.1
-
111
-
-
0035107985
-
Identification of a cytotoxic T lymphocyte response to the apoptosis inhibitor protein survivin in cancer patients
-
Andersen, M. H., Pedersen, L. O., Becker, J. C. & Straten, P. T. Identification of a cytotoxic T lymphocyte response to the apoptosis inhibitor protein survivin in cancer patients. Cancer Res. 61, 869-872 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 869-872
-
-
Andersen, M.H.1
Pedersen, L.O.2
Becker, J.C.3
Straten, P.T.4
-
112
-
-
0036848113
-
Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer
-
Yamamoto, T., Manome, Y., Nakamura, M. & Tanigawa, N. Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer. Eur. J. Cancer 38, 2316-2324 (2002).
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 2316-2324
-
-
Yamamoto, T.1
Manome, Y.2
Nakamura, M.3
Tanigawa, N.4
-
113
-
-
0035895282
-
Inhibition of melanoma tumor growth in vivo by survivin targeting
-
Grossman, D., Kim, P. J., Schechner, J. S. & Altieri, D. C. Inhibition of melanoma tumor growth in vivo by survivin targeting. Proc. Natl Acad. Sci. USA 98, 635-640 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 635-640
-
-
Grossman, D.1
Kim, P.J.2
Schechner, J.S.3
Altieri, D.C.4
-
114
-
-
0036220822
-
Complexities in the development of cyclin-dependent kinase inhibitor drugs
-
Sausville, E. A. Complexities in the development of cyclin-dependent kinase inhibitor drugs. Trends Mol. Med. 8, S32-S37 (2002).
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Sausville, E.A.1
-
115
-
-
0037089691
-
Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors
-
Schwartz, G. K. et al. Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors. J. Clin. Oncol. 20, 2157-2170 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2157-2170
-
-
Schwartz, G.K.1
-
116
-
-
0032954260
-
Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
-
Tao, W. et al. Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nature Genet. 21, 177-181 (1999).
-
(1999)
Nature Genet.
, vol.21
, pp. 177-181
-
-
Tao, W.1
-
117
-
-
9544220641
-
A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer
-
Theile, M. et al. A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer. Oncogene 13, 677-685 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 677-685
-
-
Theile, M.1
-
118
-
-
85047699404
-
LATS1 tumor suppressor regulates G2/M transition and apoptosis
-
Xia, H. et al. LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene 21, 1233-1241 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 1233-1241
-
-
Xia, H.1
-
119
-
-
0031037222
-
Construction by gene targeting in human cells of a 'conditional' CDC2 mutant that rereplicates its DNA
-
Itzhaki, J. E., Gilbert, C. S. & Porter, A. C. G. Construction by gene targeting in human cells of a 'conditional' CDC2 mutant that rereplicates its DNA. Nature Genet. 15, 258-265 (1997).
-
(1997)
Nature Genet.
, vol.15
, pp. 258-265
-
-
Itzhaki, J.E.1
Gilbert, C.S.2
Porter, A.C.G.3
-
120
-
-
0029116545
-
Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage
-
Ongkeko, W., Ferguson, D. J. P., Harris, A. L. & Norbury, C. Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage. J. Cell Sci. 108, 2897-2904 (1995).
-
(1995)
J. Cell Sci.
, vol.108
, pp. 2897-2904
-
-
Ongkeko, W.1
Ferguson, D.J.P.2
Harris, A.L.3
Norbury, C.4
-
121
-
-
0032563315
-
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
-
Gray N. S. et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281, 533-538 (1998).
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.S.1
-
122
-
-
0032214980
-
Cdc2 kinase
-
Cdc2 kinase. Mol. Cell 2, 581-591 (1998).
-
(1998)
Mol. Cell
, vol.2
, pp. 581-591
-
-
Yu, D.1
-
123
-
-
0033870417
-
Control of apoptosis during angiogenesis by survivin expression in endothelial cells
-
O'Connor, D. S. et al. Control of apoptosis during angiogenesis by survivin expression in endothelial cells. Am. J. Pathol. 156, 393-398 (2000).
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 393-398
-
-
O'Connor, D.S.1
-
124
-
-
0033517840
-
Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells
-
Tran, J. et al. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochem. Biophys. Res. Commun. 264, 781-788 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 781-788
-
-
Tran, J.1
-
125
-
-
0035024053
-
Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting
-
Mesri, M. et al. Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting. Am. J. Pathol. 158, 1757-1765 (2001).
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1757-1765
-
-
Mesri, M.1
-
126
-
-
0034641932
-
From bench to clinic with apoptosis-based therapeutic agents
-
Nicholson, D. W. From bench to clinic with apoptosis-based therapeutic agents. Nature 407, 810-816 (2000).
-
(2000)
Nature
, vol.407
, pp. 810-816
-
-
Nicholson, D.W.1
|