메뉴 건너뛰기




Volumn 3, Issue 1, 2003, Pages 37-52

Genetic variation of human UDP-glucuronosyltransferase: Implications in disease and drug glucuronidation

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; ATAZANAVIR; BILE ACID; BILIRUBIN; CARCINOGEN; CLOFIBRATE; CLOMIPRAMINE; CYTARABINE; DEXTRORPHAN; DIPHENHYDRAMINE; DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; FENOFIBRATE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; IRINOTECAN; LORAZEPAM; MERCAPTOPURINE; PARACETAMOL; PESTICIDE; PIRARUBICIN; PREDNISOLONE; RIFAMPICIN; SAQUINAVIR; STEROID; TOLBUTAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCRISTINE; XENOBIOTIC AGENT; ZIDOVUDINE;

EID: 0037223551     PISSN: 11752203     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129785-200303010-00006     Document Type: Review
Times cited : (92)

References (144)
  • 2
    • 0001177611 scopus 로고
    • The uridine diphosphate glucuronosyltransferase multigene family: Function and regulation
    • Clarke DJ, Burchell B. The uridine diphosphate glucuronosyltransferase multigene family: function and regulation. Handb Exper Pharmcol 1994; 112: 3-43
    • (1994) Handb Exper Pharmcol , vol.112 , pp. 3-43
    • Clarke, D.J.1    Burchell, B.2
  • 3
    • 0001643397 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferases
    • Sipes IG, Gandolfi AJ, Mcqueen CA, editors. Amsterdam: Pergamon Elsevier Science
    • Burchell B, McGurk K, Brierley CH, et al. UDP-glucuronosyltransferases. In: Sipes IG, Gandolfi AJ, Mcqueen CA, editors. Comprehensive toxicology. Vol. 3. Amsterdam: Pergamon Elsevier Science, 1997: 401-35
    • (1997) Comprehensive Toxicology , vol.3 , pp. 401-435
    • Burchell, B.1    McGurk, K.2    Brierley, C.H.3
  • 4
    • 0027692685 scopus 로고
    • Human UDP-glucuronosyltransferases: Chemical defence, jaundice and gene therapy
    • Brierley CH, Burchell B. Human UDP-glucuronosyltransferases: chemical defence, jaundice and gene therapy. Bioessays 1993; 15: 749-54
    • (1993) Bioessays , vol.15 , pp. 749-754
    • Brierley, C.H.1    Burchell, B.2
  • 5
    • 0026532030 scopus 로고
    • Acyl glucuronides revisited: Is the glucuronidation process a toxification as well as detoxification mechanism?
    • Spahn-Langguth H, Benet LZ. Acyl glucuronides revisited: is the glucuronidation process a toxification as well as detoxification mechanism? Drug Metab Rev 1992; 24: 5-48
    • (1992) Drug Metab Rev , vol.24 , pp. 5-48
    • Spahn-Langguth, H.1    Benet, L.Z.2
  • 6
    • 0028875109 scopus 로고
    • Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
    • Burchell B, Brierley CH, Rance D. Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation. Life Sci 1995; 57: 1819-31
    • (1995) Life Sci , vol.57 , pp. 1819-1831
    • Burchell, B.1    Brierley, C.H.2    Rance, D.3
  • 7
    • 0027242397 scopus 로고
    • Validation and use of cloned, expressed human drug metabolising enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions
    • Remmel RP, Burchell B. Validation and use of cloned, expressed human drug metabolising enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions. Biochem Pharmacol 1993; 46: 559-66
    • (1993) Biochem Pharmacol , vol.46 , pp. 559-566
    • Remmel, R.P.1    Burchell, B.2
  • 8
    • 0035115599 scopus 로고    scopus 로고
    • Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract
    • Tukey RH, Strassburg CP. Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract. Mol Pharmacol 2001; 59: 405-14
    • (2001) Mol Pharmacol , vol.59 , pp. 405-414
    • Tukey, R.H.1    Strassburg, C.P.2
  • 9
    • 0032707765 scopus 로고    scopus 로고
    • Structural and functional studies of UDP-Glucuronosyltransferases
    • Radominska-Pandya A, Czernik PJ, Little JM, et al. Structural and functional studies of UDP-Glucuronosyltransferases. Drug Metab Rev 1999; 31: 817-99
    • (1999) Drug Metab Rev , vol.31 , pp. 817-899
    • Radominska-Pandya, A.1    Czernik, P.J.2    Little, J.M.3
  • 10
    • 0025773294 scopus 로고
    • The UDP glucuronosyltransferase gene superfamily: Suggested nomenclature based on evolutionary divergence
    • Burchell B, Nebert DW, Nelson DR, et al. The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence. DNA Cell Biol 1991; 10: 487-94
    • (1991) DNA Cell Biol , vol.10 , pp. 487-494
    • Burchell, B.1    Nebert, D.W.2    Nelson, D.R.3
  • 11
    • 8544224973 scopus 로고    scopus 로고
    • The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
    • Mackenzie P, Owens IS, Burchell B, et al. The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 1997; 7: 255-69
    • (1997) Pharmacogenetics , vol.7 , pp. 255-269
    • Mackenzie, P.1    Owens, I.S.2    Burchell, B.3
  • 12
    • 0026665547 scopus 로고
    • Chromosomal assignment of human phenol and bilirubin UDP-glucuronosyltransferase genes (UGT1A Subfamily)
    • Moghrabi N, Sutherland L, Wooster R, et al. Chromosomal assignment of human phenol and bilirubin UDP-glucuronosyltransferase genes (UGT1A Subfamily). Ann Hum Genet 1992; 56: 83-93
    • (1992) Ann Hum Genet , vol.56 , pp. 83-93
    • Moghrabi, N.1    Sutherland, L.2    Wooster, R.3
  • 13
    • 0026879233 scopus 로고
    • The novel bilirubin/phenol UDP-glucuronosyltransferase UGT 1 gene locus: Implications for multiple nonhemolytic familial hyperbilirubinaemia phenotypes
    • Owens IS, Ritter JK. The novel bilirubin/phenol UDP-glucuronosyltransferase UGT 1 gene locus: implications for multiple nonhemolytic familial hyperbilirubinaemia phenotypes. Pharmacogenetics 1992; 2: 93-108
    • (1992) Pharmacogenetics , vol.2 , pp. 93-108
    • Owens, I.S.1    Ritter, J.K.2
  • 14
    • 0025861217 scopus 로고
    • Cloning and stable expression of a new member of the human liver phenol/bilirubin UDP-glucuronosyltransferase cDNA family
    • Wooster R, Sutherland L, Ebner T, et al. Cloning and stable expression of a new member of the human liver phenol/bilirubin UDP-glucuronosyltransferase cDNA family. Biochem J 1991; 278: 465-9
    • (1991) Biochem J , vol.278 , pp. 465-469
    • Wooster, R.1    Sutherland, L.2    Ebner, T.3
  • 15
    • 0034966656 scopus 로고    scopus 로고
    • Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus
    • Gong Q-H, Cho JW, Huang T, et al. Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. Pharmacogenetics 2001; 11: 357-68
    • (2001) Pharmacogenetics , vol.11 , pp. 357-368
    • Gong, Q.-H.1    Cho, J.W.2    Huang, T.3
  • 17
    • 0026736260 scopus 로고
    • Localization of a bile acid UDP-glucuronosyltransferase gene UGT2B to chromosome 4 using the polymerase chain reaction
    • Monaghan G, Povey S, Burchell B, et al. Localization of a bile acid UDP-glucuronosyltransferase gene UGT2B to chromosome 4 using the polymerase chain reaction. Genomics 1992; 13: 908-9
    • (1992) Genomics , vol.13 , pp. 908-909
    • Monaghan, G.1    Povey, S.2    Burchell, B.3
  • 18
    • 0028136583 scopus 로고
    • Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13
    • Monaghan G, Clarke DJ, Povey S, et al. Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13. Genomics 1994; 23: 496-9
    • (1994) Genomics , vol.23 , pp. 496-499
    • Monaghan, G.1    Clarke, D.J.2    Povey, S.3
  • 19
    • 0034050743 scopus 로고    scopus 로고
    • Genomic organisation of the UGT2B gene cluster on human chromosome 4q13
    • Reidy M, Wang J-Y, Miller AP, et al. Genomic organisation of the UGT2B gene cluster on human chromosome 4q13. Pharmacogenetics 2000; 10: 251-60
    • (2000) Pharmacogenetics , vol.10 , pp. 251-260
    • Reidy, M.1    Wang, J.-Y.2    Miller, A.P.3
  • 20
    • 0035103197 scopus 로고    scopus 로고
    • Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members
    • Turgeon D, Carrier J-S, Levesque E, et al. Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members. Endocrinology 2001; 142: 778-87
    • (2001) Endocrinology , vol.142 , pp. 778-787
    • Turgeon, D.1    Carrier, J.-S.2    Levesque, E.3
  • 21
    • 0033564554 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human olfactory UGT
    • Jedlitschky G, Cassidy AJ, Sales M, et al. Cloning and characterization of a novel human olfactory UGT. Biochem J 1999; 340: 837-43
    • (1999) Biochem J , vol.340 , pp. 837-843
    • Jedlitschky, G.1    Cassidy, A.J.2    Sales, M.3
  • 22
    • 0025284207 scopus 로고
    • The UDP-glucuronosyltransferases: A family of detoxifying enzymes
    • Tephly TR, Burchell B. The UDP-glucuronosyltransferases: a family of detoxifying enzymes. Trends Pharmacol Sci 1990; 11: 276-9
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 276-279
    • Tephly, T.R.1    Burchell, B.2
  • 23
    • 0027991904 scopus 로고
    • Investigation of the substrate-specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation
    • Senafi SB, Clarke DJ, Burchell B. Investigation of the substrate-specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. Biochem J 1994; 303: 233-40
    • (1994) Biochem J , vol.303 , pp. 233-240
    • Senafi, S.B.1    Clarke, D.J.2    Burchell, B.3
  • 24
    • 0025831505 scopus 로고
    • Interindividual variability in the glucuronidation and sulphation of ethinyloestradiol in human liver
    • Temellini A, Giuliani L, Pacifici GM. Interindividual variability in the glucuronidation and sulphation of ethinyloestradiol in human liver. Br J Clin Pharmacol 1991; 31: 661-4
    • (1991) Br J Clin Pharmacol , vol.31 , pp. 661-664
    • Temellini, A.1    Giuliani, L.2    Pacifici, G.M.3
  • 25
    • 0035154231 scopus 로고    scopus 로고
    • Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney
    • Soars MG, Riley RJ, Findlay KAB, et al. Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney. Drug Metab Dispos 2001; 29: 121-6
    • (2001) Drug Metab Dispos , vol.29 , pp. 121-126
    • Soars, M.G.1    Riley, R.J.2    Findlay, K.A.B.3
  • 26
    • 0024390969 scopus 로고
    • UDP-glucuronyltransferases in "genetic factors influencing the metabolism of foreign compounds"
    • Burchell B, Coughtrie MWH. UDP-glucuronyltransferases in "genetic factors influencing the metabolism of foreign compounds". Pharmacol Ther 1989; 43: 261-89
    • (1989) Pharmacol Ther , vol.43 , pp. 261-289
    • Burchell, B.1    Coughtrie, M.W.H.2
  • 27
    • 0003144221 scopus 로고
    • Expression and co-induction of CYP1A1 and UGT1*6 in human lungs
    • Vainio H, Elovaara E, Luukkanen L, et al. Expression and co-induction of CYP1A1 and UGT1*6 in human lungs. Eur J Drug Metab Pharmacokinet 1995; Special Issue: 47-8
    • (1995) Eur J Drug Metab Pharmacokinet , Issue.SPEC. ISSUE , pp. 47-48
    • Vainio, H.1    Elovaara, E.2    Luukkanen, L.3
  • 28
    • 0032705773 scopus 로고    scopus 로고
    • Ethnic differences in N-glucuronidation of nicotine and cotinine
    • Benowitz NL, Perez-Stable E, Fong I, et al. Ethnic differences in N-glucuronidation of nicotine and cotinine. J Pharmacol Exp Ther 1999; 291: 1196-203
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 1196-1203
    • Benowitz, N.L.1    Perez-Stable, E.2    Fong, I.3
  • 29
    • 0029092399 scopus 로고
    • Metabolism of clomipramine in a Japanese psychiatric population: Hydroxylation, desmethylation, and glucuronidation
    • Shimoda K, Noguchi T, Ozeki Y, et al. Metabolism of clomipramine in a Japanese psychiatric population: hydroxylation, desmethylation, and glucuronidation. Neuropsychopharmacology 1995; 12: 323-33
    • (1995) Neuropsychopharmacology , vol.12 , pp. 323-333
    • Shimoda, K.1    Noguchi, T.2    Ozeki, Y.3
  • 30
    • 0028018821 scopus 로고
    • The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes
    • Bock KW, Schrenk D, Forster A, et al. The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes. Pharmacogenetics 1994; 4: 209-18
    • (1994) Pharmacogenetics , vol.4 , pp. 209-218
    • Bock, K.W.1    Schrenk, D.2    Forster, A.3
  • 31
    • 0025873406 scopus 로고
    • Urinary glucuronide excretion of fenofibric and clofibric acid glucuronides in man: Is it polymorphic
    • Liu HF, Vincentviry M, Galteau MM, et al. Urinary glucuronide excretion of fenofibric and clofibric acid glucuronides in man: is it polymorphic. Eur J Clin Pharmacol 1991; 41: 153-9
    • (1991) Eur J Clin Pharmacol , vol.41 , pp. 153-159
    • Liu, H.F.1    Vincentviry, M.2    Galteau, M.M.3
  • 32
    • 0028821440 scopus 로고
    • Lack of a genetic polymorphism in the glucuronidation of fenofibric acid
    • Vincent-Viry M, Cossy C, Galteau MM, et al. Lack of a genetic polymorphism in the glucuronidation of fenofibric acid. Pharmacogenetics 1995; 5: 50-2
    • (1995) Pharmacogenetics , vol.5 , pp. 50-52
    • Vincent-Viry, M.1    Cossy, C.2    Galteau, M.M.3
  • 33
    • 0027234212 scopus 로고
    • Dextromethorphan O-demethylation and dextrorphan glucuronidation in a French population
    • Duche JC, Querol-Ferrer V, Barre J, et al. Dextromethorphan O-demethylation and dextrorphan glucuronidation in a French population. Int J Clin Pharmacol Ther Toxicol 1993; 31: 392-8
    • (1993) Int J Clin Pharmacol Ther Toxicol , vol.31 , pp. 392-398
    • Duche, J.C.1    Querol-Ferrer, V.2    Barre, J.3
  • 34
    • 0030838552 scopus 로고    scopus 로고
    • Variability of diphenhydramine N-glucuronidation in healthy subjects
    • Fischer D, Breyer-Pfaff U. Variability of diphenhydramine N-glucuronidation in healthy subjects. Eur J Drug Metab Pharmacokinet 1997; 22: 151-4
    • (1997) Eur J Drug Metab Pharmacokinet , vol.22 , pp. 151-154
    • Fischer, D.1    Breyer-Pfaff, U.2
  • 35
    • 0030847925 scopus 로고    scopus 로고
    • Intra-individual variation in serum AZT is not related to intestinal absorption or small intestinal inflammatory changes in human HIV-infected subjects
    • Sherwood RA, Marsden JT, Stein CA, et al. Intra-individual variation in serum AZT is not related to intestinal absorption or small intestinal inflammatory changes in human HIV-infected subjects. Antivir Chem Chemother 1997; 8: 327-32
    • (1997) Antivir Chem Chemother , vol.8 , pp. 327-332
    • Sherwood, R.A.1    Marsden, J.T.2    Stein, C.A.3
  • 36
    • 0001517022 scopus 로고    scopus 로고
    • Interindividual variation in the levels of certain urinary polycyclic aromatic hydrocarbon metabolites following medicinal exposure to coal tar ointment
    • Bowman ED, Rothman N, Hackl C, et al. Interindividual variation in the levels of certain urinary polycyclic aromatic hydrocarbon metabolites following medicinal exposure to coal tar ointment. Biomarkers 1997; 2: 321-7
    • (1997) Biomarkers , vol.2 , pp. 321-327
    • Bowman, E.D.1    Rothman, N.2    Hackl, C.3
  • 37
    • 0035197725 scopus 로고    scopus 로고
    • Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms
    • Court MH, Duan SX, Van Moltke LL, et al. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. J Pharmacol Exp Ther 2001; 299: 988-1006
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 988-1006
    • Court, M.H.1    Duan, S.X.2    Van Moltke, L.L.3
  • 38
    • 0036266930 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-1α is a causal factor responsible for interindividual differences in the expression of UDP-Glucuronosyltransferase 2B7 mRNA in human livers
    • Toide K, Takahashi Y, Yamazaki H, et al. Hepatocyte nuclear factor-1α is a causal factor responsible for interindividual differences in the expression of UDP-Glucuronosyltransferase 2B7 mRNA in human livers. Drug Metab Dispos 2002; 30: 613-5
    • (2002) Drug Metab Dispos , vol.30 , pp. 613-615
    • Toide, K.1    Takahashi, Y.2    Yamazaki, H.3
  • 39
    • 0343924387 scopus 로고    scopus 로고
    • Regulation of the human bilirubin UDP-Glucuronosyltransferase gene
    • Brierley CH, Senafi SB, Clarke D, et al. Regulation of the human bilirubin UDP-Glucuronosyltransferase gene. Adv Enzyme Regul 1996; 36: 85-97
    • (1996) Adv Enzyme Regul , vol.36 , pp. 85-97
    • Brierley, C.H.1    Senafi, S.B.2    Clarke, D.3
  • 40
    • 0030765649 scopus 로고    scopus 로고
    • Disruption of the c/ebpα gene in adult mouse liver
    • Lee Y-H, Sauer B, Johnson PF, et al. Disruption of the c/ebpα gene in adult mouse liver. Mol Cell Biol 1997; 17: 6014-22
    • (1997) Mol Cell Biol , vol.17 , pp. 6014-6022
    • Lee, Y.-H.1    Sauer, B.2    Johnson, P.F.3
  • 41
    • 0028867826 scopus 로고
    • The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
    • Bosma PJ, Roy Chowdhury J, Bakker C, et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333: 1171-218
    • (1995) N Engl J Med , vol.333 , pp. 1171-1218
    • Bosma, P.J.1    Roy Chowdhury, J.2    Bakker, C.3
  • 42
    • 0030030762 scopus 로고    scopus 로고
    • Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
    • Monaghan G, Ryan MF, et al. Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet 1996; 347: 578-81
    • (1996) Lancet , vol.347 , pp. 578-581
    • Monaghan, G.1    Ryan, M.F.2
  • 43
    • 18444399926 scopus 로고    scopus 로고
    • Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinaemia
    • Sugatani J, Yamakawa K, Yoshinari K, et al. Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinaemia, Biochem Biophys Res Commun 2002; 292: 492-7
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 492-497
    • Sugatani, J.1    Yamakawa, K.2    Yoshinari, K.3
  • 44
    • 12244271026 scopus 로고    scopus 로고
    • Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups
    • Innocenti F, Grimsley C, Das S, et al. Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics 2002; 12: 725-33
    • (2002) Pharmacogenetics , vol.12 , pp. 725-733
    • Innocenti, F.1    Grimsley, C.2    Das, S.3
  • 45
    • 0028811175 scopus 로고
    • Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam
    • Patel M, Tang BK, Grant DM, et al. Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam. Pharmacogenetics 1995; 5: 287-97
    • (1995) Pharmacogenetics , vol.5 , pp. 287-297
    • Patel, M.1    Tang, B.K.2    Grant, D.M.3
  • 46
    • 0033645752 scopus 로고    scopus 로고
    • Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: Ethnic diversity of alleles and potential clinical significance
    • Bhasker CR, McKinnon W, Stone A, et al. Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance. Pharmacogenetics 2000; 10: 679-85
    • (2000) Pharmacogenetics , vol.10 , pp. 679-685
    • Bhasker, C.R.1    McKinnon, W.2    Stone, A.3
  • 47
    • 0029015847 scopus 로고
    • Gilbert's syndrome is caused by heterozygous missense mutation in the gene for bilirubin UDP-glucuronosyltransferase
    • Koiwai O, Nishizawa M, Hasada K, et al. Gilbert's syndrome is caused by heterozygous missense mutation in the gene for bilirubin UDP-glucuronosyltransferase. Hum Mol Genet 1995; 4: 1183-6
    • (1995) Hum Mol Genet , vol.4 , pp. 1183-1186
    • Koiwai, O.1    Nishizawa, M.2    Hasada, K.3
  • 48
    • 0030699360 scopus 로고    scopus 로고
    • Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: Pharmacological implications
    • Ciotti M, Marrone A, Potter C, et al. Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications. Pharmacogenetics 1997; 7: 485-95
    • (1997) Pharmacogenetics , vol.7 , pp. 485-495
    • Ciotti, M.1    Marrone, A.2    Potter, C.3
  • 49
    • 0033789766 scopus 로고    scopus 로고
    • Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: Functional consequences of three novel missense mutations in the human UGT1A7 gene
    • Guillemette C, Ritter JK, Auyeung DJ, et al. Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene. Pharmacogenetics 2000; 10: 629-44
    • (2000) Pharmacogenetics , vol.10 , pp. 629-644
    • Guillemette, C.1    Ritter, J.K.2    Auyeung, D.J.3
  • 50
    • 0034765595 scopus 로고    scopus 로고
    • Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene
    • Vogel A, Kneip S, Barut A, et al. Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology 2001; 121: 1136-44
    • (2001) Gastroenterology , vol.121 , pp. 1136-1144
    • Vogel, A.1    Kneip, S.2    Barut, A.3
  • 51
    • 0012356560 scopus 로고    scopus 로고
    • The tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with oralaryngeal cancer risk in Caucasian and African Americans
    • Zheng Z, Guillemette C, Park JY, et al. The tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with oralaryngeal cancer risk in Caucasian and African Americans. J Natl Cancer Inst 2001; 29: 1343-8
    • (2001) J Natl Cancer Inst , vol.29 , pp. 1343-1348
    • Zheng, Z.1    Guillemette, C.2    Park, J.Y.3
  • 52
    • 0036016310 scopus 로고    scopus 로고
    • Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3
    • Huang Y-H, Galijatovic A, Nguyen N, et al. Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1. UGT1A8*2 and UGT1A8*3. Pharmacogenetics 2002; 12: 287-97
    • (2002) Pharmacogenetics , vol.12 , pp. 287-297
    • Huang, Y.-H.1    Galijatovic, A.2    Nguyen, N.3
  • 53
    • 0032812606 scopus 로고    scopus 로고
    • Characterization and substrate specificity of UGT2B4 (E458), a UDP-Glucuronosyltransferase encoded by a polymorphic gene
    • Levesque E, Beaulieu M, Hum D, et al. Characterization and substrate specificity of UGT2B4 (E458), a UDP-Glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics 1999; 9: 207-16
    • (1999) Pharmacogenetics , vol.9 , pp. 207-216
    • Levesque, E.1    Beaulieu, M.2    Hum, D.3
  • 54
    • 0036842042 scopus 로고    scopus 로고
    • Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9
    • Court MH, Duan SX, Guillemette C, et al. Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9. Drug Metab Dispos 2002; 30: 1257-65
    • (2002) Drug Metab Dispos , vol.30 , pp. 1257-1265
    • Court, M.H.1    Duan, S.X.2    Guillemette, C.3
  • 55
    • 0030795936 scopus 로고    scopus 로고
    • T1: Islation and characterization of UGT2B15(Y-85): A UDP-glucuronosyltransferase encoded by a polymorphic gene
    • Levesque E, Beaulieu M, Green MD, et al. T1: islation and characterization of UGT2B15(Y-85): A UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics 1997; 7: 317-25
    • (1997) Pharmacogenetics , vol.7 , pp. 317-325
    • Levesque, E.1    Beaulieu, M.2    Green, M.D.3
  • 56
    • 0030728222 scopus 로고    scopus 로고
    • Genetic defects of the UDP-glucuronosyltransferase-1 (UGT1) gene that cause familial non-haemolytic unconjugated hyperbilirubinaemias
    • Clarke DJ, Moghrabi N, Monaghan G, et al. Genetic defects of the UDP-glucuronosyltransferase-1 (UGT1) gene that cause familial non-haemolytic unconjugated hyperbilirubinaemias. Clin Chim Acta 1997; 266: 63-74
    • (1997) Clin Chim Acta , vol.266 , pp. 63-74
    • Clarke, D.J.1    Moghrabi, N.2    Monaghan, G.3
  • 57
    • 0001400656 scopus 로고
    • Chronic unconjugated hyperbilirubinaemia without overt signs of hemolysis in adolescents and adults
    • Arias IM. Chronic unconjugated hyperbilirubinaemia without overt signs of hemolysis in adolescents and adults. J Clin Invest 1962; 41: 2233-45
    • (1962) J Clin Invest , vol.41 , pp. 2233-2245
    • Arias, I.M.1
  • 58
    • 0012343828 scopus 로고
    • Studies on the inheritance of Crigler-Najjar syndrome by the menthol test
    • Szabo L, Ebrey P. Studies on the inheritance of Crigler-Najjar syndrome by the menthol test. Acta Paediatr Scand 1963; 4: 153-8
    • (1963) Acta Paediatr Scand , vol.4 , pp. 153-158
    • Szabo, L.1    Ebrey, P.2
  • 59
    • 0014579106 scopus 로고
    • Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyltransferase deficiency: Clinical, biochemical, pharmacologic and genetic evidence for heterogeneity
    • Arias IM, Gartner LM, Cohen M, et al. Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyltransferase deficiency: clinical, biochemical, pharmacologic and genetic evidence for heterogeneity. Am J Med 1969; 47: 395-409
    • (1969) Am J Med , vol.47 , pp. 395-409
    • Arias, I.M.1    Gartner, L.M.2    Cohen, M.3
  • 60
    • 0012355291 scopus 로고
    • Bilirubin metabolism in congenital nonhemolytic jaundice
    • Bloomer JR, Berk PD, Howe RB, et al. Bilirubin metabolism in congenital nonhemolytic jaundice. Pediatr Res 1971; 5: 256-64
    • (1971) Pediatr Res , vol.5 , pp. 256-264
    • Bloomer, J.R.1    Berk, P.D.2    Howe, R.B.3
  • 61
    • 0034458006 scopus 로고    scopus 로고
    • Characterization of the UGTs catalysing thyroid hormone glucuronidation in man
    • Findlay K, Burchell B. Characterization of the UGTs catalysing thyroid hormone glucuronidation in man. J Clin Endocrinol 2000; 85: 2879-83
    • (2000) J Clin Endocrinol , vol.85 , pp. 2879-2883
    • Findlay, K.1    Burchell, B.2
  • 62
    • 0030221217 scopus 로고    scopus 로고
    • The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1
    • King CD, Green MD, Rios GR, et al. The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. Arch Biochem Biophys 1996; 332: 92-100
    • (1996) Arch Biochem Biophys , vol.332 , pp. 92-100
    • King, C.D.1    Green, M.D.2    Rios, G.R.3
  • 63
    • 0027521059 scopus 로고
    • Human bilirubin UDP-glucuronosyltransferase catalyses the glucuronidation of ethinylestradiol
    • Ebner T, Burchell B, Remmel RP. Human bilirubin UDP-glucuronosyltransferase catalyses the glucuronidation of ethinylestradiol. Mol Pharmacol 1993; 43: 649-54
    • (1993) Mol Pharmacol , vol.43 , pp. 649-654
    • Ebner, T.1    Burchell, B.2    Remmel, R.P.3
  • 64
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan (CPT11)
    • Iyer L, King CD, Whitington PF, et al. Genetic predisposition to the metabolism of irinotecan (CPT11). J Clin Invest 1998; 101: 847-54
    • (1998) J Clin Invest , vol.101 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3
  • 65
    • 0027422955 scopus 로고
    • Cosegration of intragenic markers with a novel mutation that causes Crigler-Najjar Syndrome type 1: Implications for carrier detection and prenatal diagnosis
    • Moghrabi N, Clarke DJ, Burchell B, et al. Cosegration of intragenic markers with a novel mutation that causes Crigler-Najjar Syndrome type 1: implications for carrier detection and prenatal diagnosis. Am J Hum Genet 1993; 53: 722-9
    • (1993) Am J Hum Genet , vol.53 , pp. 722-729
    • Moghrabi, N.1    Clarke, D.J.2    Burchell, B.3
  • 66
    • 0019846078 scopus 로고
    • Pathogenesis of Gilbert's syndrome
    • Fevery J. Pathogenesis of Gilbert's syndrome. Eur J Clin Invest 1981; 11: 417-8
    • (1981) Eur J Clin Invest , vol.11 , pp. 417-418
    • Fevery, J.1
  • 68
    • 0023187951 scopus 로고
    • Normal pathways for glucuronidation, sulphation and oxidation of paracetamol in Gilbert's syndrome
    • Ullrich D, Sieg A, Blume R, et al. Normal pathways for glucuronidation, sulphation and oxidation of paracetamol in Gilbert's syndrome. Eur J Clin Invest 1987; 17: 237-40
    • (1987) Eur J Clin Invest , vol.17 , pp. 237-240
    • Ullrich, D.1    Sieg, A.2    Blume, R.3
  • 69
    • 0026545451 scopus 로고
    • Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome
    • De Morais SMF, Uetrecht JP, Wells PG. Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome. Gastroenterology 1992; 102: 577-86
    • (1992) Gastroenterology , vol.102 , pp. 577-586
    • De Morais, S.M.F.1    Uetrecht, J.P.2    Wells, P.G.3
  • 70
    • 0033841077 scopus 로고    scopus 로고
    • Association of human liver bilirubin UDP-glucuronosyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene
    • Raijmakers MT, Jansen PL, Steegers EA, et al. Association of human liver bilirubin UDP-glucuronosyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene. J Hepatol 2000; 33: 348-51
    • (2000) J Hepatol , vol.33 , pp. 348-351
    • Raijmakers, M.T.1    Jansen, P.L.2    Steegers, E.A.3
  • 71
  • 72
    • 0036157862 scopus 로고    scopus 로고
    • Genetic polymorphisms of UDP-glucuronosyltransferase in Asians: UGT1A1*28 is a common allele in Indians
    • Balram C, Sabapathy K, Fei G, et al. Genetic polymorphisms of UDP-glucuronosyltransferase in Asians: UGT1A1*28 is a common allele in Indians. Pharmacogenetics 2002; 12: 81-3
    • (2002) Pharmacogenetics , vol.12 , pp. 81-83
    • Balram, C.1    Sabapathy, K.2    Fei, G.3
  • 73
    • 0031850241 scopus 로고    scopus 로고
    • TATA-box promoter mutant in the promoter of UDP-glucuronosyltransferase gene in Italian patients with Gilbert's syndrome
    • Sampietro M, Lupica L, Perrero L, et al. TATA-box promoter mutant in the promoter of UDP-glucuronosyltransferase gene in Italian patients with Gilbert's syndrome. Ital J Gastroenterol Hepatol 1998; 30: 194-8
    • (1998) Ital J Gastroenterol Hepatol , vol.30 , pp. 194-198
    • Sampietro, M.1    Lupica, L.2    Perrero, L.3
  • 74
    • 0033054393 scopus 로고    scopus 로고
    • Contribution of the TATA-Box genotype (Gilbert's syndrome) to serum bilirubin concentrations in the Italian population
    • Biondi ML, Turri O, Dilillo E, et al. Contribution of the TATA-Box genotype (Gilbert's syndrome) to serum bilirubin concentrations in the Italian population. Clin Chem 1999; 45: 897-8
    • (1999) Clin Chem , vol.45 , pp. 897-898
    • Biondi, M.L.1    Turri, O.2    Dilillo, E.3
  • 75
    • 0032493441 scopus 로고    scopus 로고
    • Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism
    • Beutler E, Gelbert T, Demina A, et al. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism. Proc Natl Acad Sci U S A 1998; 95: 8170-4
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8170-8174
    • Beutler, E.1    Gelbert, T.2    Demina, A.3
  • 76
    • 17744374081 scopus 로고    scopus 로고
    • Polymorphism in the promoter region of the bilirubin UDP-glucuronosyltransferase (Gilbert's syndrome) in healthy Dutch subjects [letter]
    • te Morsche RHM, Zusterzeel PLM, Raijmakers MTM, et al. Polymorphism in the promoter region of the bilirubin UDP-glucuronosyltransferase (Gilbert's syndrome) in healthy Dutch subjects [letter]. Hepatology 2001; 33: 765
    • (2001) Hepatology , vol.33 , pp. 765
    • Te Morsche, R.H.M.1    Zusterzeel, P.L.M.2    Raijmakers, M.T.M.3
  • 77
    • 0033802568 scopus 로고    scopus 로고
    • Molecular diagnosis of a familial nonhemolytic hyperbilirubinaemia (Gilbert healthy subjects)
    • Borlak J, Thum T, Landt O, et al. Molecular diagnosis of a familial nonhemolytic hyperbilirubinaemia (Gilbert healthy subjects). Hepatology 2000; 32: 792-5
    • (2000) Hepatology , vol.32 , pp. 792-795
    • Borlak, J.1    Thum, T.2    Landt, O.3
  • 78
    • 0031595660 scopus 로고    scopus 로고
    • The UGT1A1*28 allele is relatively rare in a Japanese population
    • Ando Y, Chida M, Nakayama K, et al. The UGT1A1*28 allele is relatively rare in a Japanese population. Pharmacogenet 1998; 8: 357-60
    • (1998) Pharmacogenet , vol.8 , pp. 357-360
    • Ando, Y.1    Chida, M.2    Nakayama, K.3
  • 79
    • 0030053274 scopus 로고    scopus 로고
    • The genetic basis of Gilbert's syndrome
    • Sato H, Adachi Y, Koiwai O. The genetic basis of Gilbert's syndrome. Lancet 1996; 347: 557-8
    • (1996) Lancet , vol.347 , pp. 557-558
    • Sato, H.1    Adachi, Y.2    Koiwai, O.3
  • 80
    • 0031719562 scopus 로고    scopus 로고
    • Neonatal hyperbilirubinaemia and mutation of bilirubin UDP-glucuronosyltransferase gene: A common missense mutation among Japanese, Koreans and Chinese
    • Akaba K, Kimura T, Sasaki A, et al. Neonatal hyperbilirubinaemia and mutation of bilirubin UDP-glucuronosyltransferase gene: a common missense mutation among Japanese, Koreans and Chinese. Biochem Mol Biol Int 1998; 46: 21-6
    • (1998) Biochem Mol Biol Int , vol.46 , pp. 21-26
    • Akaba, K.1    Kimura, T.2    Sasaki, A.3
  • 81
    • 0031864410 scopus 로고    scopus 로고
    • Contribution of two missense mutation (G71R and Y486D) of the bilirubin UDP-glucuronosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II
    • Yamamoto K, Sato H, Fujiyama Y, et al. Contribution of two missense mutation (G71R and Y486D) of the bilirubin UDP-glucuronosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II. Biochim Biophys Acta 1998; 1406: 267-73
    • (1998) Biochim Biophys Acta , vol.1406 , pp. 267-273
    • Yamamoto, K.1    Sato, H.2    Fujiyama, Y.3
  • 82
    • 0028904620 scopus 로고
    • Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome
    • Aono S, Adachi Y, Uyama E, et al. Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome. Lancet 1995; 345: 958-9
    • (1995) Lancet , vol.345 , pp. 958-959
    • Aono, S.1    Adachi, Y.2    Uyama, E.3
  • 83
    • 0033816138 scopus 로고    scopus 로고
    • Variations of the bilirubin in uridine-diphosphoglucuronosyltransferase 1A1 gene in healthy Taiwanese
    • Huang C-S, Luo G-A, Huang M-H, et al. Variations of the bilirubin in uridine-diphosphoglucuronosyltransferase 1A1 gene in healthy Taiwanese. Pharmacogenetics 2000; 10: 539-44
    • (2000) Pharmacogenetics , vol.10 , pp. 539-544
    • Huang, C.-S.1    Luo, G.-A.2    Huang, M.-H.3
  • 84
    • 0029774577 scopus 로고    scopus 로고
    • Evidence for overlapping active sites for 17α-Ethinylestradiol and bilirubin in the human major bilirubin UDPglucuronosyltransferase
    • Ciotti M, Owens IS. Evidence for overlapping active sites for 17α-Ethinylestradiol and bilirubin in the human major bilirubin UDPglucuronosyltransferase. Biochem 1996; 35: 10119-24
    • (1996) Biochem , vol.35 , pp. 10119-10124
    • Ciotti, M.1    Owens, I.S.2
  • 85
    • 0033661491 scopus 로고    scopus 로고
    • Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: Relationship between UGT1A1 promoter genotype and variability in a liver bank
    • Fisher MB, Vanden Branden M, Findlay K, et al. Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank. Pharmacogenetics 2000; 10: 727-39
    • (2000) Pharmacogenetics , vol.10 , pp. 727-739
    • Fisher, M.B.1    Vanden Branden, M.2    Findlay, K.3
  • 86
    • 0030716924 scopus 로고    scopus 로고
    • Severe CPT-11 toxicity in patients with Gilbert's syndrome: Two case reports
    • Wasserman E, Myara A, Lokiec F, et al. Severe CPT-11 toxicity in patients with Gilbert's syndrome: two case reports. Ann Oncol 1997; 810: 1049-51
    • (1997) Ann Oncol , vol.810 , pp. 1049-1051
    • Wasserman, E.1    Myara, A.2    Lokiec, F.3
  • 87
    • 0030958098 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic evaluation of the topoisomerase inhibitor irinotecan in cancer patients
    • Gupta E, Mick R, Ramirez J, et al. Pharmacokinetic and pharmacodynamic evaluation of the topoisomerase inhibitor irinotecan in cancer patients. J Clin Oncol 1997; 15: 1502-10
    • (1997) J Clin Oncol , vol.15 , pp. 1502-1510
    • Gupta, E.1    Mick, R.2    Ramirez, J.3
  • 88
    • 0031926749 scopus 로고    scopus 로고
    • Pathophysiology and therapy of irinotecan-induced onset diarrhoea in patients with advanced colorectal cancer
    • Saliba F, Higipantelli R, Misset JL, et al. Pathophysiology and therapy of irinotecan-induced onset diarrhoea in patients with advanced colorectal cancer. J Clin Oncol 1998; 16: 2745-51
    • (1998) J Clin Oncol , vol.16 , pp. 2745-2751
    • Saliba, F.1    Higipantelli, R.2    Misset, J.L.3
  • 89
    • 0031661579 scopus 로고    scopus 로고
    • UGT1A1 genotypes and glucuronidation of SN-38, the active metabolite of irinotecan
    • Ando Y, Saka H, Asai G, et al. UGT1A1 genotypes and glucuronidation of SN-38, the active metabolite of irinotecan. Ann Oncol 1998; 9: 845-7
    • (1998) Ann Oncol , vol.9 , pp. 845-847
    • Ando, Y.1    Saka, H.2    Asai, G.3
  • 90
    • 0032934383 scopus 로고    scopus 로고
    • Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism
    • Iyer L, Hall D, Das S, et al. Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism. Clin Pharmacol Ther 1999; 65: 576-82
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 576-582
    • Iyer, L.1    Hall, D.2    Das, S.3
  • 91
    • 0036025450 scopus 로고    scopus 로고
    • UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
    • Iyer L, Das S, Janisch L, et al. UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J 2002; 2: 43-7
    • (2002) Pharmacogenomics J , vol.2 , pp. 43-47
    • Iyer, L.1    Das, S.2    Janisch, L.3
  • 92
    • 0036148810 scopus 로고    scopus 로고
    • Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan
    • Ando Y, Ueoka H, Sugiyama T, et al. Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan. Ther Drug Monit 2002; 24: 111-6
    • (2002) Ther Drug Monit , vol.24 , pp. 111-116
    • Ando, Y.1    Ueoka, H.2    Sugiyama, T.3
  • 93
    • 0033600191 scopus 로고    scopus 로고
    • Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus
    • Ciotti M, Basu N, Brangi M, et al. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus. Biochem Biophys Res Commun 1999; 260: 199-202
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 199-202
    • Ciotti, M.1    Basu, N.2    Brangi, M.3
  • 94
    • 0034778246 scopus 로고    scopus 로고
    • Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidfation of 7-ethyl-10-hydroxycamptothecin
    • Hanioka N, Ozawa S, Jinno H, et al. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidfation of 7-ethyl-10-hydroxycamptothecin. Xenobiotica 2001; 31: 687-99
    • (2001) Xenobiotica , vol.31 , pp. 687-699
    • Hanioka, N.1    Ozawa, S.2    Jinno, H.3
  • 95
    • 0031827877 scopus 로고    scopus 로고
    • Inhibition of intestinal microflora beta-glucuronidase modifes the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats
    • Takasuna K, Hagiwara T, Hirohashi M, et al. Inhibition of intestinal microflora beta-glucuronidase modifes the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats. Cancer Chemother Pharmacol 1998; 42: 280-6
    • (1998) Cancer Chemother Pharmacol , vol.42 , pp. 280-286
    • Takasuna, K.1    Hagiwara, T.2    Hirohashi, M.3
  • 96
    • 0035147198 scopus 로고    scopus 로고
    • Chemotherapy-induced unconjugated hyperbilirubinaemia caused by a mutation of the bilirubin uridine-5′-diphosphate glucuronosyltransferase gene
    • Maruo Y, Sata H, Bamba N, et al. Chemotherapy-induced unconjugated hyperbilirubinaemia caused by a mutation of the bilirubin uridine-5′-diphosphate glucuronosyltransferase gene. J Pediatr Hematol Oncol 2001; 23: 45-7
    • (2001) J Pediatr Hematol Oncol , vol.23 , pp. 45-47
    • Maruo, Y.1    Sata, H.2    Bamba, N.3
  • 97
    • 0037986926 scopus 로고    scopus 로고
    • Relationship between UDP-glucuronosyltransferase 1A1 genotype and total bilirubin elevation in healthy subjects receiving BMS-232632 and saquinavir
    • Sep 17-21. Toronto, Canada
    • O'Mara EM, Mummanemi V, Burchell B, et al. Relationship between UDP-glucuronosyltransferase 1A1 genotype and total bilirubin elevation in healthy subjects receiving BMS-232632 and saquinavir [abstract]. 40th ICAAC Meeting; 2000 Sep 17-21. Toronto, Canada
    • (2000) 40th ICAAC Meeting
    • O'Mara, E.M.1    Mummanemi, V.2    Burchell, B.3
  • 98
    • 0035940414 scopus 로고    scopus 로고
    • Mechanism of indinavir-induced hyperbilirubinaemia
    • Zucker SD, Qin X, Rouster SD, et al. Mechanism of indinavir-induced hyperbilirubinaemia. Proc Natl Acad Sci (USA) 2001; 98: 12671-6
    • (2001) Proc Natl Acad Sci (USA) , vol.98 , pp. 12671-12676
    • Zucker, S.D.1    Qin, X.2    Rouster, S.D.3
  • 99
    • 0028567847 scopus 로고
    • Disposition of Lorazepam in Gilbert's Syndrome: Effects of fasting, feeding, and enterohepatic circulation
    • Herman RJ, Chaudhary A, Szakacs CB. Disposition of Lorazepam in Gilbert's Syndrome: effects of fasting, feeding, and enterohepatic circulation. J Clin Pharmacol 1994; 34: 978-84
    • (1994) J Clin Pharmacol , vol.34 , pp. 978-984
    • Herman, R.J.1    Chaudhary, A.2    Szakacs, C.B.3
  • 100
    • 0001747399 scopus 로고
    • Hereditary jaundice and disorders of bilirubin metabolism
    • Scriver CR, Beaudet A, Sly W, et al., editors. New York: McGraw-Hill
    • Chowdhury RJ, Wolkoff A, Chowdhury RN, et al. Hereditary jaundice and disorders of bilirubin metabolism. In: Scriver CR, Beaudet A, Sly W, et al., editors. The metabolic basis of inherited disease. New York: McGraw-Hill, 1995; 2161-208
    • (1995) The Metabolic Basis of Inherited Disease , pp. 2161-2208
    • Chowdhury, R.J.1    Wolkoff, A.2    Chowdhury, R.N.3
  • 101
    • 0018574014 scopus 로고
    • Postnatal development of uridine, diphosphate glucuronosyltransferase activity towads bilirubin and 2-aminophenol in human liver
    • Onishi S, Kawade N, Itoh S, et al. Postnatal development of uridine, diphosphate glucuronosyltransferase activity towads bilirubin and 2-aminophenol in human liver. Biochem J 1979; 184: 705-7
    • (1979) Biochem J , vol.184 , pp. 705-707
    • Onishi, S.1    Kawade, N.2    Itoh, S.3
  • 102
    • 0000621679 scopus 로고
    • Prolonged neonatal unconjugated hyperbilirubinaemia associated with breast-feeding and a steroid, pregnane-3α,20β-diol in maternal milk that inhibits glucuronide formation in vitro
    • Arias IM, Gartner LM, Seifter S, et al. Prolonged neonatal unconjugated hyperbilirubinaemia associated with breast-feeding and a steroid, pregnane-3α,20β-diol in maternal milk that inhibits glucuronide formation in vitro. J Clin Invest 1964; 43: 2037-47
    • (1964) J Clin Invest , vol.43 , pp. 2037-2047
    • Arias, I.M.1    Gartner, L.M.2    Seifter, S.3
  • 103
    • 0017861029 scopus 로고
    • Clinical study of prolonged jaundice in breast and bottle-fed babies
    • Winfield CR, MacFaul R. Clinical study of prolonged jaundice in breast and bottle-fed babies. Arch Dis Child 1978; 54: 506-7
    • (1978) Arch Dis Child , vol.54 , pp. 506-507
    • Winfield, C.R.1    MacFaul, R.2
  • 104
    • 0021238953 scopus 로고
    • Jaundice in the full-term neonate
    • Osborn LM, Reiff M, Bolus R. Jaundice in the full-term neonate. Pediatrics 1984; 73: 520-5
    • (1984) Pediatrics , vol.73 , pp. 520-525
    • Osborn, L.M.1    Reiff, M.2    Bolus, R.3
  • 105
    • 0023936363 scopus 로고
    • Jaundice in the healthy newborn infant: A new approach to an old problem
    • Maisels MK, Gifford K, Antle CE, et al. Jaundice in the healthy newborn infant: a new approach to an old problem. Pediatrics 1988; 81: 505-11
    • (1988) Pediatrics , vol.81 , pp. 505-511
    • Maisels, M.K.1    Gifford, K.2    Antle, C.E.3
  • 106
    • 0020639259 scopus 로고
    • Neonatal jaundice in full-term infants: Role of breast-feeding and other causes
    • Maisels MJ, Gifford K. Neonatal jaundice in full-term infants: role of breast-feeding and other causes. Am J Dis Child 1983; 137: 561-2
    • (1983) Am J Dis Child , vol.137 , pp. 561-562
    • Maisels, M.J.1    Gifford, K.2
  • 107
    • 0031949264 scopus 로고    scopus 로고
    • Gilbert's syndrome accelerates development of neonatal jaundice
    • Bancroft JD, Kreamer B, Gourley GR. Gilbert's syndrome accelerates development of neonatal jaundice. J Paediatr 1998; 132: 656-60
    • (1998) J Paediatr , vol.132 , pp. 656-660
    • Bancroft, J.D.1    Kreamer, B.2    Gourley, G.R.3
  • 108
    • 0033510908 scopus 로고    scopus 로고
    • Gilbert's syndrome is a contributory factor in very prolonged unconjugated hyperbilirubinaema of the newborn
    • Monaghan G, McLellan A, McGeechan A, et al. Gilbert's syndrome is a contributory factor in very prolonged unconjugated hyperbilirubinaema of the newborn. J Pediatr 1999; 134: 441-6
    • (1999) J Pediatr , vol.134 , pp. 441-446
    • Monaghan, G.1    McLellan, A.2    McGeechan, A.3
  • 109
    • 0016242097 scopus 로고
    • Navajo jaundice: A variant of neonatal hyperbilirubinaemia associated with breast-feeding
    • Saland J, McNamara H, Cohen MI. Navajo jaundice: a variant of neonatal hyperbilirubinaemia associated with breast-feeding. J Pediatr 1974; 85: 271-5
    • (1974) J Pediatr , vol.85 , pp. 271-275
    • Saland, J.1    McNamara, H.2    Cohen, M.I.3
  • 110
    • 0018216093 scopus 로고
    • Jaundice and breast-feeding among Alaska Eskimo newborns
    • Fisher Q, Cohen MI, Curda L. Jaundice and breast-feeding among Alaska Eskimo newborns. Am J Dis Child 1978; 132: 859-63
    • (1978) Am J Dis Child , vol.132 , pp. 859-863
    • Fisher, Q.1    Cohen, M.I.2    Curda, L.3
  • 111
    • 0027085807 scopus 로고
    • Jaundice in Navajo neonates
    • Johnson JD. Jaundice in Navajo neonates. Clin Paediatr (Phila) 1992; 12: 716-8
    • (1992) Clin Paediatr (Phila) , vol.12 , pp. 716-718
    • Johnson, J.D.1
  • 112
    • 0031705604 scopus 로고    scopus 로고
    • Severe neonatal hyperbilirubinaemia: A potential complication of glucose-6-phosphate dehydrogenase deficiency
    • Kaplan M, Hammerman C. Severe neonatal hyperbilirubinaemia: a potential complication of glucose-6-phosphate dehydrogenase deficiency. Clin Perinatol 1998; 25: 575-92
    • (1998) Clin Perinatol , vol.25 , pp. 575-592
    • Kaplan, M.1    Hammerman, C.2
  • 113
    • 0030691028 scopus 로고    scopus 로고
    • Gilbert's syndrome and glucose-6-phosphate dehydrogenase deficiency: A dose-dependent genetic interaction crucial to neonatal hyperbilirubinaemia
    • Kaplan M, Renbaum P, Levy-Lahad E, et al. Gilbert's syndrome and glucose-6-phosphate dehydrogenase deficiency: a dose-dependent genetic interaction crucial to neonatal hyperbilirubinaemia. Proc Natl Acad Sci U S A 1997; 94: 12128-32
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12128-12132
    • Kaplan, M.1    Renbaum, P.2    Levy-Lahad, E.3
  • 114
    • 0030663191 scopus 로고    scopus 로고
    • The expression of UDP-glucuronosyltransferase is a major determinant ofbilirubin level in heterozygous β-thalassaemia and in glucose-6-phosphate dehydrogenase deficiency
    • Sanpietro M, Lupica L, Perrero L, et al. The expression of UDP-glucuronosyltransferase is a major determinant ofbilirubin level in heterozygous β-thalassaemia and in glucose-6-phosphate dehydrogenase deficiency. Br J Haematol 1997; 99: 437-9
    • (1997) Br J Haematol , vol.99 , pp. 437-439
    • Sanpietro, M.1    Lupica, L.2    Perrero, L.3
  • 115
    • 0032845453 scopus 로고    scopus 로고
    • Hyperbilirubinaemia, glucose-6-phosphate dehydrogenase deficiency and Gilbert's syndrome
    • Gollanello R, Cipollino MD, Carboni G, et al. Hyperbilirubinaemia, glucose-6-phosphate dehydrogenase deficiency and Gilbert's syndrome. Eur J Pediatr 1999; 158: 914-6
    • (1999) Eur J Pediatr , vol.158 , pp. 914-916
    • Gollanello, R.1    Cipollino, M.D.2    Carboni, G.3
  • 116
    • 0034686969 scopus 로고    scopus 로고
    • Gilbert's syndrome and hyperbilirubinaemia in ABO-incompatible neonates
    • Kaplan M, Hammerman C, Renbaum P, et al. Gilbert's syndrome and hyperbilirubinaemia in ABO-incompatible neonates. Lancet 2000; 356: 652-3
    • (2000) Lancet , vol.356 , pp. 652-653
    • Kaplan, M.1    Hammerman, C.2    Renbaum, P.3
  • 117
    • 0008435402 scopus 로고    scopus 로고
    • Coinheritance of Gilbert's syndrome increases the risk of developing gallstones in patients with hereditary spherocytosis
    • del Guidice EM, Perotta S, Nobili B, et al. Coinheritance of Gilbert's syndrome increases the risk of developing gallstones in patients with hereditary spherocytosis. Blood 1999; 94: 2259-62
    • (1999) Blood , vol.94 , pp. 2259-2262
    • Del Guidice, E.M.1    Perotta, S.2    Nobili, B.3
  • 118
    • 0033943506 scopus 로고    scopus 로고
    • Gilbert's syndrome accounts for the phenotypic variability of congenital dyserthropoietic anaemia type II
    • Perrotta S, del Giudice EM, Carbane R, et al. Gilbert's syndrome accounts for the phenotypic variability of congenital dyserthropoietic anaemia type II. J Pediatr 2000; 136: 556-9
    • (2000) J Pediatr , vol.136 , pp. 556-559
    • Perrotta, S.1    Del Giudice, E.M.2    Carbane, R.3
  • 119
    • 0036204931 scopus 로고    scopus 로고
    • Hemolysis and bilirubin conjugation in association with UDP-glucuronosyltransferase 1A1 promoter polymorphism
    • Kaplan M, Hammerman C, Rubaltelli FF, et al. Hemolysis and bilirubin conjugation in association with UDP-glucuronosyltransferase 1A1 promoter polymorphism. Hepatology 2002; 35: 905-11
    • (2002) Hepatology , vol.35 , pp. 905-911
    • Kaplan, M.1    Hammerman, C.2    Rubaltelli, F.F.3
  • 120
    • 0032884336 scopus 로고    scopus 로고
    • Jaundice with hypertrophic pyloric stenosis as an early manifestation of Gilbert's Syndrome
    • Trioche P, Chalas J, Francoual J, et al. Jaundice with hypertrophic pyloric stenosis as an early manifestation of Gilbert's Syndrome. Arch Dis Child 1999; 81: 301-3
    • (1999) Arch Dis Child , vol.81 , pp. 301-303
    • Trioche, P.1    Chalas, J.2    Francoual, J.3
  • 121
    • 0032852420 scopus 로고    scopus 로고
    • Co-inherited Gilbert's syndrome: A factor determining hyperbilirubinaemia in homozygous beta-thalassemia
    • Galanello R, Cipollina MD, Dessi C, et al. Co-inherited Gilbert's syndrome: a factor determining hyperbilirubinaemia in homozygous beta-thalassemia. Haematologica 1999; 84: 103-5
    • (1999) Haematologica , vol.84 , pp. 103-105
    • Galanello, R.1    Cipollina, M.D.2    Dessi, C.3
  • 122
    • 4243464375 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferase (UGT1A1) promoter polymorphism and bilirubin levels in patients with sickle cell disease [abstract 861]
    • McKie K, Kutlar F, Sromek S, et al. UDP-glucuronosyltransferase (UGT1A1) promoter polymorphism and bilirubin levels in patients with sickle cell disease [abstract 861]. Blood 1999; 94: P197a
    • (1999) Blood , vol.94
    • McKie, K.1    Kutlar, F.2    Sromek, S.3
  • 123
    • 4244134019 scopus 로고    scopus 로고
    • The effect of UDP-glucuronosyltransferase (UGT1A1) promoter polymorphisms on serum bilirubin levels and cholelthiasis in patients with sickle cell anaemia [abstract 2865]
    • Passon RG, Howard TA, Zimmerman SA, et al. The effect of UDP-glucuronosyltransferase (UGT1A1) promoter polymorphisms on serum bilirubin levels and cholelthiasis in patients with sickle cell anaemia [abstract 2865]. Blood 1999; 94: P645a
    • (1999) Blood , vol.94
    • Passon, R.G.1    Howard, T.A.2    Zimmerman, S.A.3
  • 124
    • 0033849474 scopus 로고    scopus 로고
    • Effect of bilirubin UDP-glucuronosyltransferase 1 gene TATA box genotypes on serum bilirubin concentrations in chronic liver injuries
    • Doyama H, Okada T, Kobayashi T, et al. Effect of bilirubin UDP-glucuronosyltransferase 1 gene TATA box genotypes on serum bilirubin concentrations in chronic liver injuries. Hepatology 2000; 32: 563-8
    • (2000) Hepatology , vol.32 , pp. 563-568
    • Doyama, H.1    Okada, T.2    Kobayashi, T.3
  • 125
    • 0034652640 scopus 로고    scopus 로고
    • Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans
    • Guillemette C, Millikan RC, Newman B, et al. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res 2000; 60: 950-6
    • (2000) Cancer Res , vol.60 , pp. 950-956
    • Guillemette, C.1    Millikan, R.C.2    Newman, B.3
  • 126
    • 0027256828 scopus 로고
    • Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferase
    • Bock KW, Forster A, Gschaidmeier H, et al. Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferase. Biochem Pharmacol 1993; 45: 1809-14
    • (1993) Biochem Pharmacol , vol.45 , pp. 1809-1814
    • Bock, K.W.1    Forster, A.2    Gschaidmeier, H.3
  • 127
    • 0025840257 scopus 로고
    • Interethnic differences in drug glucuronidation: A comparison of paracetamol metabolism in Caucasians and Chinese
    • Osborne NJ, Tonkin AL, Miners JO. Interethnic differences in drug glucuronidation: a comparison of paracetamol metabolism in Caucasians and Chinese. Br J Clin Pharmacol 1991; 32: 765-7
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 765-767
    • Osborne, N.J.1    Tonkin, A.L.2    Miners, J.O.3
  • 128
    • 0027530118 scopus 로고
    • Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family
    • Ebner T, Burchell B. Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family. Drug Metab Dispos 1993; 21: 50-5
    • (1993) Drug Metab Dispos , vol.21 , pp. 50-55
    • Ebner, T.1    Burchell, B.2
  • 129
    • 0032529231 scopus 로고    scopus 로고
    • Cloning and expression of human UDP-glucuronosyltransferase 1A8
    • Cheng Z, Radominska-Paydya A, Tephly TR. Cloning and expression of human UDP-glucuronosyltransferase 1A8. Arch Biophys Biochem 1998; 356: 301-5
    • (1998) Arch Biophys Biochem , vol.356 , pp. 301-305
    • Cheng, Z.1    Radominska-Paydya, A.2    Tephly, T.R.3
  • 130
    • 0033786733 scopus 로고    scopus 로고
    • The COMT inhibitors and entacapone and tolcapone are good substrates for UGT1A4 and UGT1A9
    • Lautala P, Ethell B, Burchell B, et al. The COMT inhibitors and entacapone and tolcapone are good substrates for UGT1A4 and UGT1A9. Drug Metab Dispos 2000; 28: 1385-9
    • (2000) Drug Metab Dispos , vol.28 , pp. 1385-1389
    • Lautala, P.1    Ethell, B.2    Burchell, B.3
  • 131
    • 0032502764 scopus 로고    scopus 로고
    • Expression of the UDP-glucuronosyltransferase 1A locus in human colon
    • Strassburg CP, Mann MP, Tukey RH. Expression of the UDP-glucuronosyltransferase 1A locus in human colon. J Biol Chem 1998; 273: 8719-26
    • (1998) J Biol Chem , vol.273 , pp. 8719-8726
    • Strassburg, C.P.1    Mann, M.P.2    Tukey, R.H.3
  • 132
    • 0024579299 scopus 로고
    • Expression of a human liver cDNA encoding hydeoxycholic acid UDP-glucuronosyltransferase in cell culture
    • Fournel-Gigleux S, Jackson MR, Wooster R, et al. Expression of a human liver cDNA encoding hydeoxycholic acid UDP-glucuronosyltransferase in cell culture. FEBS Lett 1989; 243: 119-22
    • (1989) FEBS Lett , vol.243 , pp. 119-122
    • Fournel-Gigleux, S.1    Jackson, M.R.2    Wooster, R.3
  • 133
    • 0027431814 scopus 로고
    • Glucuronidation of hyodeoxycholic acid in human liver: Evidence for a selective role of UGT2B4
    • Pillot T, Ouzzine M, Fournel-Gigleux S, et al. Glucuronidation of hyodeoxycholic acid in human liver: evidence for a selective role of UGT2B4. J Biol Chem 1993; 268: 25636-42
    • (1993) J Biol Chem , vol.268 , pp. 25636-25642
    • Pillot, T.1    Ouzzine, M.2    Fournel-Gigleux, S.3
  • 134
    • 0027433317 scopus 로고
    • Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltranferase glucuronidating carboxylic acid-containing drugs
    • Jin CJ, Miners JO, Lillywhite KJ, et al. Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltranferase glucuronidating carboxylic acid-containing drugs. J Pharmacol Exp Ther 1993; 264: 475-9
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 475-479
    • Jin, C.J.1    Miners, J.O.2    Lillywhite, K.J.3
  • 135
    • 0026591504 scopus 로고
    • Two human liver cDNAs encode UDP-glucuronosyltransferase with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives
    • Ritter JK, Chen F, Sheen YY, et al. Two human liver cDNAs encode UDP-glucuronosyltransferase with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives. Biochem 1992; 31: 3409-14
    • (1992) Biochem , vol.31 , pp. 3409-3414
    • Ritter, J.K.1    Chen, F.2    Sheen, Y.Y.3
  • 136
    • 0031570313 scopus 로고    scopus 로고
    • The regio- and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11
    • Jin CJ, Mackenzie PI, Miners JO. The regio- and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11. Arch Biochem Biophys 1997; 341: 207-11
    • (1997) Arch Biochem Biophys , vol.341 , pp. 207-211
    • Jin, C.J.1    Mackenzie, P.I.2    Miners, J.O.3
  • 137
    • 0031022419 scopus 로고    scopus 로고
    • Human UGT2B7 catalyses morphine glucuronidation
    • Coffman BL, Rios GR, King CD, et al. Human UGT2B7 catalyses morphine glucuronidation. Drug Metab Dispos 1997; 25: 1-4
    • (1997) Drug Metab Dispos , vol.25 , pp. 1-4
    • Coffman, B.L.1    Rios, G.R.2    King, C.D.3
  • 138
    • 0028837971 scopus 로고
    • (S) Oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT 2B7
    • Patel M, Tang BK, Kalow W, (S) Oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT 2B7. Pharmacogentics 1995; 5: 43-29
    • (1995) Pharmacogentics , vol.5 , pp. 43-29
    • Patel, M.1    Tang, B.K.2    Kalow, W.3
  • 139
    • 0031894377 scopus 로고    scopus 로고
    • The glucuronidation of opioids, other xenobiotics and androgens by human UGT2B7Y(268) and UGT2B7H(268)
    • Coffman BL, King CD, Rios GR, et al. The glucuronidation of opioids, other xenobiotics and androgens by human UGT2B7Y(268) and UGT2B7H(268). Drug Metab Dispos 1998; 26: 73-7
    • (1998) Drug Metab Dispos , vol.26 , pp. 73-77
    • Coffman, B.L.1    King, C.D.2    Rios, G.R.3
  • 140
    • 0024355675 scopus 로고
    • Interindividual and interethnic differences in the demethylation and glucuronidation of codeine
    • Yue QY, Svensson JO, Alm C, et al. Interindividual and interethnic differences in the demethylation and glucuronidation of codeine. Br J Clin Pharmacol 1989; 28: 629-37
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 629-637
    • Yue, Q.Y.1    Svensson, J.O.2    Alm, C.3
  • 141
    • 0029003283 scopus 로고
    • Codeine metabolism in three oriental populations: A pilot study in Chinese, Japanese and Koreans
    • Yue Q-Y, Svensson J-O, Sawe J, et al. Codeine metabolism in three oriental populations: a pilot study in Chinese. Japanese and Koreans. Pharmacogenetics 1995; 5: 173-7
    • (1995) Pharmacogenetics , vol.5 , pp. 173-177
    • Yue, Q.-Y.1    Svensson, J.-O.2    Sawe, J.3
  • 142
    • 0028031001 scopus 로고
    • Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates
    • Green MD, Oturu EM, Tephly TR. Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug Metab Dispos 1994; 22: 799-805
    • (1994) Drug Metab Dispos , vol.22 , pp. 799-805
    • Green, M.D.1    Oturu, E.M.2    Tephly, T.R.3
  • 143
    • 0033637811 scopus 로고    scopus 로고
    • Determination of genetic polymorphisms in UGT2B15 by allele-specific PCR
    • MacLeod SL, Nowell SA, Lang NP. Determination of genetic polymorphisms in UGT2B15 by allele-specific PCR. Ann Surg Oncol 2000; 7: 777-82
    • (2000) Ann Surg Oncol , vol.7 , pp. 777-782
    • MacLeod, S.L.1    Nowell, S.A.2    Lang, N.P.3
  • 144
    • 0034118356 scopus 로고    scopus 로고
    • Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4 ((DE)-E-458), UGT2B7 ((HY)-Y-268), and UGT2B15((DY)-Y-85)
    • Lampe JW, Bigler J, Bush AC, et al. Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4 ((DE)-E-458), UGT2B7 ((HY)-Y-268), and UGT2B15((DY)-Y-85). Cancer Epidemiol Biomarkers Prev 2000; 9: 329-33
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 329-333
    • Lampe, J.W.1    Bigler, J.2    Bush, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.