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Volumn 16, Issue 8, 1998, Pages 2745-2751

Pathophysiology and therapy of irinotecan-induced delayed-onset diarrhea in patients with advanced colorectal cancer: A prospective assessment

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ACETORPHAN; ALPHA 1 ANTITRYPSIN; CAMPTOTHECIN DERIVATIVE; CARBOXYLESTERASE; DNA TOPOISOMERASE; ENKEPHALINASE INHIBITOR; FECES LIPID; FLUOROURACIL; FOLINIC ACID; GASTRIN; GLUCAGON; IRINOTECAN; LEVAMISOLE; LOPERAMIDE; OXALIPLATIN; PROSTAGLANDIN E2; SOMATOSTATIN; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE; XYLOSE;

EID: 0031926749     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.8.2745     Document Type: Article
Times cited : (141)

References (40)
  • 1
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • Hsiang YH, Liu LF: Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 48:1722-1726, 1988
    • (1988) Cancer Res , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 2
    • 0023552964 scopus 로고
    • Antitumor activity of 7-ethyl-10-{4-(1-piperidino)-1-piperidino} carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
    • Kunimoto T, Nitta K, Tanaka T, et al: Antitumor activity of 7-ethyl-10-{4-(1-piperidino)-1-piperidino} carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res 47:5944-5947, 1987
    • (1987) Cancer Res , vol.47 , pp. 5944-5947
    • Kunimoto, T.1    Nitta, K.2    Tanaka, T.3
  • 3
    • 0026680292 scopus 로고
    • CPT-11: A new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer
    • Masuda N, Fufuoka M, Kusunoki Y, et al: CPT-11: A new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer. J Clin Oncol 10:1225-1229, 1992
    • (1992) J Clin Oncol , vol.10 , pp. 1225-1229
    • Masuda, N.1    Fufuoka, M.2    Kusunoki, Y.3
  • 4
    • 0026531753 scopus 로고
    • A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer
    • Fukuoka M, Niitani H, Suzuki A, et al: A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer. J Clin Oncol 10:16-20, 1992
    • (1992) J Clin Oncol , vol.10 , pp. 16-20
    • Fukuoka, M.1    Niitani, H.2    Suzuki, A.3
  • 5
    • 0028276113 scopus 로고
    • Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer
    • Futatsuki K, Wakui A, Nakao I, et al: Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer. Jpn J Cancer Chemother 21:1033-1038, 1994
    • (1994) Jpn J Cancer Chemother , vol.21 , pp. 1033-1038
    • Futatsuki, K.1    Wakui, A.2    Nakao, I.3
  • 6
    • 0028839053 scopus 로고
    • Phase II trial of CPT-11 in patients with advanced pancreatic cancer, an EORTC early clinical trials group study
    • Wagener DJT, Verdonk HER, Dirix LY, et al: Phase II trial of CPT-11 in patients with advanced pancreatic cancer, an EORTC early clinical trials group study. Ann Oncol 6:129-132, 1995
    • (1995) Ann Oncol , vol.6 , pp. 129-132
    • Wagener, D.J.T.1    Verdonk, H.E.R.2    Dirix, L.Y.3
  • 7
    • 0031014627 scopus 로고    scopus 로고
    • Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy
    • Rougier P, Bugat R, Douillard JY, et al: Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy. J Clin Oncol 15:251-260, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 251-260
    • Rougier, P.1    Bugat, R.2    Douillard, J.Y.3
  • 8
    • 0025899042 scopus 로고
    • A late phase II study of CPT-11 on uterine cervical cancer and ovarian cancer
    • Takeuchi S, Dobashi K, Fujimoto S, et al: A late phase II study of CPT-11 on uterine cervical cancer and ovarian cancer. Jpn J Cancer Chemother 18:1681-1689, 1991
    • (1991) Jpn J Cancer Chemother , vol.18 , pp. 1681-1689
    • Takeuchi, S.1    Dobashi, K.2    Fujimoto, S.3
  • 9
    • 0025129894 scopus 로고
    • An early phase II study of CPT-11: A new derivative camptothecin, for the treatment of leukemia and lymphoma
    • Ohno R, Okada K, Masaoka T, et al: An early phase II study of CPT-11: A new derivative camptothecin, for the treatment of leukemia and lymphoma. J Clin Oncol 8:1907-1912, 1990
    • (1990) J Clin Oncol , vol.8 , pp. 1907-1912
    • Ohno, R.1    Okada, K.2    Masaoka, T.3
  • 10
    • 0027194943 scopus 로고
    • Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
    • Shimada Y, Yoshino M, Wakui A, et al: Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. J Clin Oncol 11:909-913, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 909-913
    • Shimada, Y.1    Yoshino, M.2    Wakui, A.3
  • 11
    • 0029966672 scopus 로고    scopus 로고
    • Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer
    • Rothenberg BM, Eckardt J, Kuhn J, et al: Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer. J Clin Oncol 14:1128-1135, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 1128-1135
    • Rothenberg, B.M.1    Eckardt, J.2    Kuhn, J.3
  • 12
    • 0029919598 scopus 로고    scopus 로고
    • Irinotecan is an active agent in untreated patients with metastatic colorectal cancer
    • Conti BJ, Kemeny N, Saltz L, et al: Irinotecan is an active agent in untreated patients with metastatic colorectal cancer. J Clin Oncol 14:709-715, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 709-715
    • Conti, B.J.1    Kemeny, N.2    Saltz, L.3
  • 13
    • 0030818926 scopus 로고    scopus 로고
    • Phase II trial of irinotecan in patients with metastatic colorectal carcinoma
    • Pitot HC, Wender DB, O'Connell MJ, et al: Phase II trial of irinotecan in patients with metastatic colorectal carcinoma. J Clin Oncol 15:2910-2919, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 2910-2919
    • Pitot, H.C.1    Wender, D.B.2    O'Connell, M.J.3
  • 14
    • 0027140524 scopus 로고
    • Phase I and pharmacokinetic trial of weekly CPT-11
    • Rothenberg ML, Kuhn JG, Burris HA III, et al: Phase I and pharmacokinetic trial of weekly CPT-11. J Clin Oncol 11:2194-2204, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 2194-2204
    • Rothenberg, M.L.1    Kuhn, J.G.2    Burris H.A. III3
  • 15
    • 13144253215 scopus 로고
    • French phase I studies of CPT-11 using 3 different schedules of administration
    • suppl 5; abstr
    • Clavel M, Extra JM, Abigerges D, et al: French phase I studies of CPT-11 using 3 different schedules of administration. Ann Oncol 3:197, 1992 (suppl 5; abstr)
    • (1992) Ann Oncol , vol.3 , pp. 197
    • Clavel, M.1    Extra, J.M.2    Abigerges, D.3
  • 16
    • 0028854897 scopus 로고
    • Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients
    • Abigerges D, Chabot G, Armand JP, et al: Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients. J Clin Oncol 13:210-221, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 210-221
    • Abigerges, D.1    Chabot, G.2    Armand, J.P.3
  • 17
    • 0028346901 scopus 로고
    • Irinotecan (CPT-11) high-dose escalation using intensive high-dose loperamide to control diarrhea
    • Abigerges D, Armand JP, Chabot GG, et al: Irinotecan (CPT-11) high-dose escalation using intensive high-dose loperamide to control diarrhea. J Natl Cancer Inst 86:446-449, 1994
    • (1994) J Natl Cancer Inst , vol.86 , pp. 446-449
    • Abigerges, D.1    Armand, J.P.2    Chabot, G.G.3
  • 18
    • 0028050008 scopus 로고
    • Preventive effect of TJ-14, a kampo (chinese herb) medicine, on diarrhea induced by irinotecan hydrochloride (CPT-11)
    • Sakata Y, Suzuki H, Kamataki T: Preventive effect of TJ-14, a kampo (chinese herb) medicine, on diarrhea induced by irinotecan hydrochloride (CPT-11). Jpn J Cancer Chemother 21:1241-1244, 1994
    • (1994) Jpn J Cancer Chemother , vol.21 , pp. 1241-1244
    • Sakata, Y.1    Suzuki, H.2    Kamataki, T.3
  • 19
    • 0027534590 scopus 로고
    • CPT-11-induced cholinergic effects in cancer patients
    • Gandia D, Abigerges D, Armand JP, et al: CPT-11-induced cholinergic effects in cancer patients. J Clin Oncol 11:196-197, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 196-197
    • Gandia, D.1    Abigerges, D.2    Armand, J.P.3
  • 20
    • 0000055806 scopus 로고
    • A phase I trial of CPT-11 in solid tumors with G-CSF and antidiarrheal support
    • abstr
    • Lestingi TM, Yokes EE, Gray W, et al: A phase I trial of CPT-11 in solid tumors with G-CSF and antidiarrheal support. Proc Am Soc Clin Oncol 14:1563, 1995 (abstr).
    • (1995) Proc am Soc Clin Oncol , vol.14 , pp. 1563
    • Lestingi, T.M.1    Yokes, E.E.2    Gray, W.3
  • 21
    • 0027189946 scopus 로고
    • Loperamide: Survey of studies on mechanism of its antidiarrheal activity
    • Awouters F, Megens A, Verlinden M, et al: Loperamide: Survey of studies on mechanism of its antidiarrheal activity. Dig Dis Sci 38:977-995, 1993
    • (1993) Dig Dis Sci , vol.38 , pp. 977-995
    • Awouters, F.1    Megens, A.2    Verlinden, M.3
  • 22
    • 0019159355 scopus 로고
    • Rational design of enkephalinase inhibitors: Substrate specficity of enkephalinase studied from inhibitory potency of various dipeptides
    • Llorens C, Gacel G, Swerts JP, et al: Rational design of enkephalinase inhibitors: Substrate specficity of enkephalinase studied from inhibitory potency of various dipeptides. Biochem Biophys Res Commun 96:1710-1716, 1980
    • (1980) Biochem Biophys Res Commun , vol.96 , pp. 1710-1716
    • Llorens, C.1    Gacel, G.2    Swerts, J.P.3
  • 23
    • 0022500375 scopus 로고
    • Pharmacological properties of acetorphan, a parenterally active enkephalinase inhibitor
    • Lecomte JM, Costentin J, Vlaiculescu A, et al: Pharmacological properties of acetorphan, a parenterally active enkephalinase inhibitor. J Pharmacol Exp Ther 237:937-944, 1986
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 937-944
    • Lecomte, J.M.1    Costentin, J.2    Vlaiculescu, A.3
  • 24
    • 0026530238 scopus 로고
    • Effects of acetorphan, an enkephalinase inhibitor, on experimental and acute diarrhea
    • Baumer Ph, Danquechin-Dorval E, Bertrand J, et al: Effects of acetorphan, an enkephalinase inhibitor, on experimental and acute diarrhea. Gut 33:753-758, 1992
    • (1992) Gut , vol.33 , pp. 753-758
    • Baumer, Ph.1    Danquechin-Dorval, E.2    Bertrand, J.3
  • 25
    • 0027584322 scopus 로고
    • The enkephalinase inhibitor, acetorphan, in acute diarrhea: A double-blind, controlled clinical trial versus loperamide
    • Roge J, Baumer P, Berard H, et al: The enkephalinase inhibitor, acetorphan, in acute diarrhea: A double-blind, controlled clinical trial versus loperamide. Scand J Gastroenterol 28:352-354, 1993
    • (1993) Scand J Gastroenterol , vol.28 , pp. 352-354
    • Roge, J.1    Baumer, P.2    Berard, H.3
  • 26
    • 0029089939 scopus 로고
    • Micropharm, a microcomputer interactive program for the analysis and simulation of pharmacokinetic processes
    • Urien S: Micropharm, a microcomputer interactive program for the analysis and simulation of pharmacokinetic processes. Pharm Res 12:1225-1230, 1995
    • (1995) Pharm Res , vol.12 , pp. 1225-1230
    • Urien, S.1
  • 27
    • 0026663423 scopus 로고
    • Fecal osmotic gap and pH in experimental diarrhea of various causes
    • Eherer A, Fordtran J: Fecal osmotic gap and pH in experimental diarrhea of various causes. Gastroenterology 103:545-551, 1992
    • (1992) Gastroenterology , vol.103 , pp. 545-551
    • Eherer, A.1    Fordtran, J.2
  • 28
    • 0021833669 scopus 로고
    • Stool electrolytes and osmolality measurements in the evaluation of diarrheal disorders
    • Shiau YF, Feldman G, Resnick M, et al: Stool electrolytes and osmolality measurements in the evaluation of diarrheal disorders. Ann Intern Med 102:773-775, 1985
    • (1985) Ann Intern Med , vol.102 , pp. 773-775
    • Shiau, Y.F.1    Feldman, G.2    Resnick, M.3
  • 29
    • 0010917253 scopus 로고    scopus 로고
    • For the pharmacology and molecular mechanisms group of the European organization for research and treatment of cancer. Pharmacokinetics and Pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer
    • Canal P, Gay C, Dezuze A, et al: For the pharmacology and molecular mechanisms group of the European organization for research and treatment of cancer. Pharmacokinetics and Pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer. J Clin Oncol 14:2688-2695, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 2688-2695
    • Canal, P.1    Gay, C.2    Dezuze, A.3
  • 30
    • 0028796944 scopus 로고
    • Drug therapy in diarrheal diseases in oncology/hematology patients
    • Cascinu S: Drug therapy in diarrheal diseases in oncology/hematology patients. Crit Rev Oncol Hematol 18:37-50, 1995
    • (1995) Crit Rev Oncol Hematol , vol.18 , pp. 37-50
    • Cascinu, S.1
  • 31
    • 84871473515 scopus 로고    scopus 로고
    • Toxicité intestinale des médicaments (estomac et duodénum exclus)
    • Elsevier, Paris, Gastroenterologie 9-100-A-15
    • Beaugerie L: Toxicité intestinale des médicaments (estomac et duodénum exclus). Encycl Méd Chir (Elsevier, Paris), Gastroenterologie 9-100-A-15:1-11, 1996
    • (1996) Encycl Méd Chir , pp. 1-11
    • Beaugerie, L.1
  • 32
    • 0029065590 scopus 로고
    • Study on the mechanisms of diarrhea induced by a new anticancer camptothecin derivative, irinotecan hydrochloride (CPT-11), in rats
    • Takasuna K, Kasai Y, Kitano Y, et al: Study on the mechanisms of diarrhea induced by a new anticancer camptothecin derivative, irinotecan hydrochloride (CPT-11), in rats. Nippon Yakurigaku Zasshi 105:447-460, 1995
    • (1995) Nippon Yakurigaku Zasshi , vol.105 , pp. 447-460
    • Takasuna, K.1    Kasai, Y.2    Kitano, Y.3
  • 33
    • 0028832819 scopus 로고
    • Irinotecan (CPT-11) and characteristic mucosal changes in the mouse ileum and cecum
    • Ikuno N, Soda H, Watanabe M, et al: Irinotecan (CPT-11) and characteristic mucosal changes in the mouse ileum and cecum. J Natl Cancer Inst 87:1876-1883, 1995
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1876-1883
    • Ikuno, N.1    Soda, H.2    Watanabe, M.3
  • 34
    • 0021216485 scopus 로고
    • Loperamide has antisecretory activity in the human jejunum in vivo
    • Hughes S, Higgs NB, Turnberg LA: Loperamide has antisecretory activity in the human jejunum in vivo. Gut 25:931-935, 1984
    • (1984) Gut , vol.25 , pp. 931-935
    • Hughes, S.1    Higgs, N.B.2    Turnberg, L.A.3
  • 35
    • 0025773538 scopus 로고
    • Loperamide but not morphine has anti-secretory effects in human colon, in vitro
    • Burleigh D: Loperamide but not morphine has anti-secretory effects in human colon, in vitro. Eur J Pharmacol 202:277-280, 1991
    • (1991) Eur J Pharmacol , vol.202 , pp. 277-280
    • Burleigh, D.1
  • 36
    • 0028840093 scopus 로고
    • Phase I pharmacokinetic study of irinotecan (CPT-11) administered daily for three consecutive days every three weeks in patients with advanced solid tumors
    • Catimel G, Chabot GG, Guastalla JP, et al: Phase I pharmacokinetic study of irinotecan (CPT-11) administered daily for three consecutive days every three weeks in patients with advanced solid tumors. Ann Oncol 6:133-140, 1995
    • (1995) Ann Oncol , vol.6 , pp. 133-140
    • Catimel, G.1    Chabot, G.G.2    Guastalla, J.P.3
  • 37
    • 0029825344 scopus 로고    scopus 로고
    • Silencing and selective methylation of the normal topoisomerase I gene in camptothecin-resistant CEM/C2 human leukemia cells
    • Fujimori A, Hoki Y, Popescu NC, et al: Silencing and selective methylation of the normal topoisomerase I gene in camptothecin-resistant CEM/C2 human leukemia cells. Oncol Res 8:295-301, 1996
    • (1996) Oncol Res , vol.8 , pp. 295-301
    • Fujimori, A.1    Hoki, Y.2    Popescu, N.C.3
  • 38
    • 0026631164 scopus 로고
    • Phase I study and pharmacokinetics of CPT-11 with 5-day continuous infusion
    • Ohe Y, Sasaki Y, Shinkai T, et al: Phase I study and pharmacokinetics of CPT-11 with 5-day continuous infusion. J Natl Cancer Inst 84:972-974, 1992
    • (1992) J Natl Cancer Inst , vol.84 , pp. 972-974
    • Ohe, Y.1    Sasaki, Y.2    Shinkai, T.3
  • 39
    • 0028947192 scopus 로고
    • Relationship between the pharmacokinetics of irinitecan and diarrhea during combination chemotherapy with cisplatin
    • Kudoh S, Fukuoka M, Masuda N, et al: Relationship between the pharmacokinetics of irinitecan and diarrhea during combination chemotherapy with cisplatin. Jpn J Cancer 86:406-413, 1995
    • (1995) Jpn J Cancer , vol.86 , pp. 406-413
    • Kudoh, S.1    Fukuoka, M.2    Masuda, N.3
  • 40
    • 0028853410 scopus 로고
    • Population pharmacokinetics and pharmacodynamics of irinotecan (CPT-11) and active metabolite SN-38 during phase I trials
    • Chabot GG, Abigerges D, Catimel G, et al: Population pharmacokinetics and pharmacodynamics of irinotecan (CPT-11) and active metabolite SN-38 during phase I trials. Ann Oncol 6:141-151, 1995
    • (1995) Ann Oncol , vol.6 , pp. 141-151
    • Chabot, G.G.1    Abigerges, D.2    Catimel, G.3


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