Genetic polymorphisms of UDP-glucuronosyltransferase in asians: UGT1A1*28 is a common allele in indians

Pharmacogenetics

Volumn 12, Issue 1, 2002, Pages 81-83

  Balram, Chowbay ^a   Sabapathy, Kanaga ^a   Fei, Gao ^a   Khoo, Kei S ^a   Lee, Edmund J D ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Asian population; Polymorphism; Serum bilirubin; UGT1A1 gene

Indexed keywords

BILIRUBIN; GLUCURONOSYLTRANSFERASE;

ALLELISM; ARTICLE; ASIAN; BILIRUBIN BLOOD LEVEL; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; HUMAN; INDIAN; MALE; PRIORITY JOURNAL;

BASE SEQUENCE; BILIRUBIN; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENOTYPE; GLUCURONOSYLTRANSFERASE; HUMANS; MALE; POLYMORPHISM, GENETIC;

EID: 0036157862     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200201000-00012     Document Type: Article

References (11)

1. Gene structure at the human UGT1 locus creates diversity in isozyme structure, structure specificity, and regulation
2. Mechanism of inherited deficiencies of multiple glucuronosyltransferase isoforms in two patients with Crigler-Najjar syndrome, type I
3. Identification of defect in the genes for bilirubin UDP glucuronosyltransferase in a patient with Crigler-Najjar syndrome type II
4. Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
5. Racial variability in the UDP-glucuronosyltransferase I (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
6. UGT1*1 genotyping in a Canadian Inuit population
7. The UGT1A1*28 allele is relatively rare in a Japanese population
8. UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: Relationships to serum bilirubin concentrations
9. Variations of the bilirubin uridine-diphosphoglucuronosyltransferase 1A1 gene in healthy Taiwanese
10. Ethnic differences in neonatal jaundice: Comparison of Japanese and Caucasian newborn infants
11. Population studies on Gilbert's syndrome