Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: A dose-dependent genetic interaction crucial to neonatal hyperbilirubinemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 22, 1997, Pages 12128-12132

  Kaplan, Michael ^a,c   Renbaum, Paul ^a   Levy Lahad, Ephrat ^a,c   Hammerman, Cathy ^a,c   Lahad, Amnon ^b,c   Beutler, Ernest ^d  

^a SHAARE ZEDEK MEDICAL CENTER   (Israel)

^b Kupat Holim Clallit Health Fund ^*  (Israel)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Bilirubin conjugation; Gene interaction; Hemolysis; Neonatal jaundice; UDP glucurosyltransferase 1

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCURONOSYLTRANSFERASE;

ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; FEMALE; GENOTYPE; GILBERT DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; JAUNDICE; KERNICTERUS; MALE; NEWBORN; NEWBORN JAUNDICE; PRIORITY JOURNAL; PROMOTER REGION;

COHORT STUDIES; FEMALE; GENE DOSAGE; GILBERT DISEASE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; GLUCURONOSYLTRANSFERASE; HUMANS; HYPERBILIRUBINEMIA; INFANT, NEWBORN; ISRAEL; JAUNDICE; JEWS; MALE; MODELS, GENETIC; MUTATION; PROMOTER REGIONS (GENETICS); RISK FACTORS; SYNDROME;

ARUNDINARIA;

EID: 0030691028     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.22.12128     Document Type: Article

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