Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 3, 2001, Pages 998-1006

  Court, Michael H ^a,d   Duan, Su X ^a   Von Moltke, Lisa L ^a   Greenblatt, David J ^a   Patten, Christopher J ^b   Miners, John O ^c   Mackenzie, Peter I ^c  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Gentest Corporation   (United States)

^c FLINDERS UNIVERSITY   (Australia)

^d TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONOSYLTRANSFERASE; PARACETAMOL;

ADOLESCENT; ADULT; AGED; ARTICLE; BINDING KINETICS; CHILD; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG GLUCURONIDATION; ENZYME ACTIVITY; ENZYME KINETICS; FEMALE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTOXICATION; LIVER MICROSOME; MAJOR CLINICAL STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN CONTENT; SEX DIFFERENCE; STATISTICAL ANALYSIS; STATISTICAL MODEL;

ACETAMINOPHEN; GLUCURONOSYLTRANSFERASE; HUMANS; ISOENZYMES; KINETICS; MICROSOMES, LIVER; SEX FACTORS; STATISTICS;

EID: 0035197725     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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