-
1
-
-
0023701349
-
Morphine-6-glucuronide. Analgesic effects and receptor binding profile in rats
-
F. V. Abbot and R. M. Palmour, Morphine-6-glucuronide. Analgesic effects and receptor binding profile in rats, Life Sci., 43, 1685 (1988).
-
(1988)
Life Sci.
, vol.43
, pp. 1685
-
-
Abbot, F.V.1
Palmour, R.M.2
-
2
-
-
0021091051
-
Steroid D-ring glucuronides: Characterization of a new class of cholestatic agents
-
M. Vore, C. Montgomery, and M. Meyers, Steroid D-ring glucuronides: Characterization of a new class of cholestatic agents, Drug Metab. Rev., 14, 1005 (1983).
-
(1983)
Drug Metab. Rev.
, vol.14
, pp. 1005
-
-
Vore, M.1
Montgomery, C.2
Meyers, M.3
-
3
-
-
0001570065
-
Steroid D-ring glucuronides: A new class of cholestatic agents
-
M. Vore and W. Slikker, Steroid D-ring glucuronides: A new class of cholestatic agents Trends Pharmacol. Sci., 6, 256 (1985).
-
(1985)
Trends Pharmacol. Sci.
, vol.6
, pp. 256
-
-
Vore, M.1
Slikker, W.2
-
4
-
-
0021238312
-
Lithocholate glucuronide is a cholestatic agent
-
D. G. Oelberg, M. V. Chari, J. M. Little, E. W. Adcock, and R. Lester, Lithocholate glucuronide is a cholestatic agent, J. Clin. Invest., 73, 1507 (1984).
-
(1984)
J. Clin. Invest.
, vol.73
, pp. 1507
-
-
Oelberg, D.G.1
Chari, M.V.2
Little, J.M.3
Adcock, E.W.4
Lester, R.5
-
5
-
-
0026605427
-
Enhancement of biological activity by conjugation reactions
-
J. A. Olson, R. C. Moon, M. W. Anders, C. Fenselau, and B. Shane, Enhancement of biological activity by conjugation reactions, J. Nutr., 122, 615 (1992).
-
(1992)
J. Nutr.
, vol.122
, pp. 615
-
-
Olson, J.A.1
Moon, R.C.2
Anders, M.W.3
Fenselau, C.4
Shane, B.5
-
6
-
-
0030296437
-
Tissue-specific 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of human UDP-glucuronosyltransferase UGT1A6
-
P. A. Munzel, G. Bookjans, G. Mehner, T. Lehmkoster, and K. W. Bock, Tissue-specific 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of human UDP-glucuronosyltransferase UGT1A6, Arch. Biochem. Biophys., 335, 205 (1996).
-
(1996)
Arch. Biochem. Biophys.
, vol.335
, pp. 205
-
-
Munzel, P.A.1
Bookjans, G.2
Mehner, G.3
Lehmkoster, T.4
Bock, K.W.5
-
7
-
-
0031873379
-
Ah receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms
-
K. W. Bock, H. Gschaidmeier, H. Heel, T. Lehmköster, P. J. Münzel, F. Raschko, and B. Bock-Henning, Ah receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms, Adv. Enzyme Regul., 38, 207 (1998).
-
(1998)
Adv. Enzyme Regul.
, vol.38
, pp. 207
-
-
Bock, K.W.1
Gschaidmeier, H.2
Heel, H.3
Lehmköster, T.4
Münzel, P.J.5
Raschko, F.6
Bock-Henning, B.7
-
9
-
-
0028295681
-
2.2Mb of contiguous nucleotide sequence from chromosome III of C. Elegans
-
R. Wilson, R. Ainscough, K. Anderson, C. Baynes, M. Berks, J. Bonfield, J. Burton, M. Connell, T. Copsey, J. Cooper, et al., 2.2Mb of contiguous nucleotide sequence from chromosome III of C. elegans, Nature, 368, 32 (1994).
-
(1994)
Nature
, vol.368
, pp. 32
-
-
Wilson, R.1
Ainscough, R.2
Anderson, K.3
Baynes, C.4
Berks, M.5
Bonfield, J.6
Burton, J.7
Connell, M.8
Copsey, T.9
Cooper, J.10
-
10
-
-
0033538021
-
Preferential expression of biotransformation enzymes in the olfactory organs of Drosophila melanogaster, the antennae
-
Q. Wang, G. Hasan, and C. W. Pikielny, Preferential expression of biotransformation enzymes in the olfactory organs of Drosophila melanogaster, the antennae, J. Biol. Chem., 274, 10,309 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10309
-
-
Wang, Q.1
Hasan, G.2
Pikielny, C.W.3
-
11
-
-
0031732138
-
UDP-Glucuronosyltransferases in human intestinal mucosa
-
A. Radominska-Pandya, J. M. Little, J. T. Pandya, T. R. Tephly, C. D. King, G. W. Barone, and J.-P. Raufman, UDP-Glucuronosyltransferases in human intestinal mucosa, Biochim. Biophys. Acta, 1394, 199 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1394
, pp. 199
-
-
Radominska-Pandya, A.1
Little, J.M.2
Pandya, J.T.3
Tephly, T.R.4
King, C.D.5
Barone, G.W.6
Raufman, J.-P.7
-
12
-
-
0030028130
-
Identification of bilirubin UDP-GTs in the human alimentary tract in accordance with the gut as a putative metabolic organ
-
W. M. McDonnell, E. Hitomi, and F. K. Askari, Identification of bilirubin UDP-GTs in the human alimentary tract in accordance with the gut as a putative metabolic organ, Biochem. Pharmacol., 51, 483 (1996).
-
(1996)
Biochem. Pharmacol.
, vol.51
, pp. 483
-
-
McDonnell, W.M.1
Hitomi, E.2
Askari, F.K.3
-
13
-
-
85034892163
-
Glutathione S-transferase, cytochrome P450, and uridine 5′-diphosphate-glucuronosyltransferase in human small intestine and liver
-
W. H. M. Peters, F. M. Nagengast, and J. H. M. van Tongeren, Glutathione S-transferase, cytochrome P450, and uridine 5′-diphosphate-glucuronosyltransferase in human small intestine and liver, Gastroenterology, 96, 783 (1989).
-
(1989)
Gastroenterology
, vol.96
, pp. 783
-
-
Peters, W.H.M.1
Nagengast, F.M.2
Van Tongeren, J.H.M.3
-
14
-
-
0023858335
-
Immunocharacterization of UDP-glucuronyltransferase isoenzymes in human liver, intestine and kidney
-
W. H. Peters and P. L. Jansen, Immunocharacterization of UDP-glucuronyltransferase isoenzymes in human liver, intestine and kidney, Biochem. Pharmacol., 37, 564 (1988).
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 564
-
-
Peters, W.H.1
Jansen, P.L.2
-
15
-
-
0021961432
-
Infante, glucuronidation of bile acids in human liver, intestine and kidney. An in vitro study on hyodeoxycholic acid
-
M. Parquet, M. Pessah, E. Sacquet, C. Salvat, A. Raizman, and R. Infante, Glucuronidation of bile acids in human liver, intestine and kidney. An in vitro study on hyodeoxycholic acid, FEBS Lett., 189, 183 (1985).
-
(1985)
FEBS Lett.
, vol.189
, pp. 183
-
-
Parquet, M.1
Pessah, M.2
Sacquet, E.3
Salvat, C.4
Raizman, A.5
-
16
-
-
0021134465
-
Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5′-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes
-
S. Matern, H. Matern, E. H. Farthmann, and W. Gerok, Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5′-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes, J. Clin. Invest., 74, 402 (1984).
-
(1984)
J. Clin. Invest.
, vol.74
, pp. 402
-
-
Matern, S.1
Matern, H.2
Farthmann, E.H.3
Gerok, W.4
-
17
-
-
0032055273
-
Drug glucuronidation by human renal UDP-glucuronosyltransferases
-
K. A. McGurk, C. H. Brierly, and B. Burchell, Drug glucuronidation by human renal UDP-glucuronosyltransferases, Biochem. Pharmacol., 55, 1005 (1998).
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 1005
-
-
McGurk, K.A.1
Brierly, C.H.2
Burchell, B.3
-
18
-
-
0022620186
-
Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and glutathione conjugation
-
G. J. Mulder, Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and glutathione conjugation, Chem. Biol. Interact., 57, 1 (1986).
-
(1986)
Chem. Biol. Interact.
, vol.57
, pp. 1
-
-
Mulder, G.J.1
-
19
-
-
0029859993
-
Hormonal regulation of hepatic enzymes involved in foreign compound metabolism
-
R. A. Prough, M. W. Linder, J. A. Pinaire, G.-H. Xiao, and K. C. Falkner, Hormonal regulation of hepatic enzymes involved in foreign compound metabolism, FASEB J., 10, 1369 (1996).
-
(1996)
FASEB J.
, vol.10
, pp. 1369
-
-
Prough, R.A.1
Linder, M.W.2
Pinaire, J.A.3
Xiao, G.-H.4
Falkner, K.C.5
-
20
-
-
0030867709
-
Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation
-
B. Burchell and M. W. H. Coughtrie, Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation, Environ. Health Persp., 105, 739 (1997).
-
(1997)
Environ. Health Persp.
, vol.105
, pp. 739
-
-
Burchell, B.1
Coughtrie, M.W.H.2
-
21
-
-
0026090495
-
Odorant signal termination by olfactory UDP glucuronosyl transferase
-
D. Lazard, K. Zupko, Y. Poria, P. Nef, J. Lazarovits, S. Horn, M. Khen, and D. Lancet, Odorant signal termination by olfactory UDP glucuronosyl transferase, Nature, 349, 790 (1991).
-
(1991)
Nature
, vol.349
, pp. 790
-
-
Lazard, D.1
Zupko, K.2
Poria, Y.3
Nef, P.4
Lazarovits, J.5
Horn, S.6
Khen, M.7
Lancet, D.8
-
22
-
-
0026376260
-
Proposed role of drug-metabolizing enzymes: Regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions
-
D. W. Nebert, Proposed role of drug-metabolizing enzymes: Regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions, Mol. Endocrinol., 5, 1203 (1991).
-
(1991)
Mol. Endocrinol.
, vol.5
, pp. 1203
-
-
Nebert, D.W.1
-
23
-
-
0028040226
-
Drug-metabolizing enzymes in ligand-modulated transcription
-
D. W. Nebert, Drug-metabolizing enzymes in ligand-modulated transcription, Biochem. Pharmacol., 47, 25 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 25
-
-
Nebert, D.W.1
-
24
-
-
0030868851
-
Cytochromes P450 and uridine triphosphate (sic)-glucuronosyltransferases: Model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease
-
M. P. Manns and P. Obermayer-Straub, Cytochromes P450 and uridine triphosphate (sic)-glucuronosyltransferases: Model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease, Hepatology, 26, 1054 (1997).
-
(1997)
Hepatology
, vol.26
, pp. 1054
-
-
Manns, M.P.1
Obermayer-Straub, P.2
-
25
-
-
0032483045
-
Required buried alphahelical structure in the bilirubin UDP-glucuronosyltransferase, UGT1A1, contains a nonreplaceable phenylalanine
-
M. Ciotti, J. W. Cho, J. George, and I. S. Owens, Required buried alphahelical structure in the bilirubin UDP-glucuronosyltransferase, UGT1A1, contains a nonreplaceable phenylalanine, Biochemistry, 37, 11018 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 11018
-
-
Ciotti, M.1
Cho, J.W.2
George, J.3
Owens, I.S.4
-
26
-
-
0345368209
-
-
IXth International Workshop on Glucuronidation and the UDP-Glucuronosyltransferases, Brisbane, Australia
-
B. L. Coffman, B. Knosp, W. R. Kearney, and T. R. Tephly, A computer designed model for the tertiary structure and opioid binding site of UGT2B7, IXth International Workshop on Glucuronidation and the UDP-Glucuronosyltransferases, Brisbane, Australia, 1998.
-
(1998)
A Computer Designed Model for the Tertiary Structure and Opioid Binding Site of UGT2B7
-
-
Coffman, B.L.1
Knosp, B.2
Kearney, W.R.3
Tephly, T.R.4
-
27
-
-
0030889553
-
Arginine 52 and Histidine 54 located in a conserved N-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6
-
C. Senay, M. Ouzzine, E. Battaglia, D. Pless, V. Cano, B. Burchell, A. Radominska, J. Magdalou, and S. Fournel-Gigleux, Arginine 52 and Histidine 54 located in a conserved N-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6, Mol. Pharmacol., 51, 406 (1997).
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 406
-
-
Senay, C.1
Ouzzine, M.2
Battaglia, E.3
Pless, D.4
Cano, V.5
Burchell, B.6
Radominska, A.7
Magdalou, J.8
Fournel-Gigleux, S.9
-
28
-
-
0030879658
-
A critical amino acid residue, asp446, in UDP-glucuronosyltransferase
-
H. Iwano, H. Yokota, S. Ohgiya, N. Yotumoto, and A. Yuasa, A critical amino acid residue, asp446, in UDP-glucuronosyltransferase, Biochem. J., 325, 587 (1997).
-
(1997)
Biochem. J.
, vol.325
, pp. 587
-
-
Iwano, H.1
Yokota, H.2
Ohgiya, S.3
Yotumoto, N.4
Yuasa, A.5
-
29
-
-
0033102535
-
The significance of amino acid residue Asp446 for enzymatic stability of rat UDP-glucuronosyltransferase UGT1A6
-
H. Iwano, H. Yokota, S. Ohgiya, and A. Yuasa, The significance of amino acid residue Asp446 for enzymatic stability of rat UDP-glucuronosyltransferase UGT1A6, Arch. Biochem. Biophys., 363, 116 (1999).
-
(1999)
Arch. Biochem. Biophys.
, vol.363
, pp. 116
-
-
Iwano, H.1
Yokota, H.2
Ohgiya, S.3
Yuasa, A.4
-
30
-
-
0030778114
-
Structure and function of uridine diphosphate glucuronosyltransferases
-
R. Meech and P. I. Mackenzie, Structure and function of uridine diphosphate glucuronosyltransferases, Clin. Exp. Pharmacol. Physiol., 24, 907 (1997).
-
(1997)
Clin. Exp. Pharmacol. Physiol.
, vol.24
, pp. 907
-
-
Meech, R.1
Mackenzie, P.I.2
-
31
-
-
0008690963
-
Bilirubin metabolism and the pathophysiology of jaundice
-
(E. R. Schiff, M. F. Sorell, and W. C. Maddrey, eds.), Lippincott-Raven, Philadelphia
-
C. L. Berg, J. M. Crawford, and J. L. Gollan, Bilirubin metabolism and the pathophysiology of jaundice, in Diseases of the Liver (E. R. Schiff, M. F. Sorell, and W. C. Maddrey, eds.), Lippincott-Raven, Philadelphia, 1999.
-
(1999)
Diseases of the Liver
-
-
Berg, C.L.1
Crawford, J.M.2
Gollan, J.L.3
-
32
-
-
0032413678
-
Biochemical and molecular aspects of genetic disorders of bilirubin metabolism
-
T. Iyanagi, Y. Emi, and S. Ikushiro, Biochemical and molecular aspects of genetic disorders of bilirubin metabolism, Biochim. Biophys. Acta, 1407, 173 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1407
, pp. 173
-
-
Iyanagi, T.1
Emi, Y.2
Ikushiro, S.3
-
33
-
-
0031706608
-
Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins
-
M. D. Green and T. R. Tephly, Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins, Drug Metab. Disp., 26, 860 (1998).
-
(1998)
Drug Metab. Disp.
, vol.26
, pp. 860
-
-
Green, M.D.1
Tephly, T.R.2
-
34
-
-
0028875109
-
Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
-
B. Burchell, C. H. Brierly, and D. Rance, Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation, Life Sci., 57, 1819 (1995).
-
(1995)
Life Sci.
, vol.57
, pp. 1819
-
-
Burchell, B.1
Brierly, C.H.2
Rance, D.3
-
35
-
-
0344936870
-
Molecular biology of the uridine diphosphate glucuronosyltransferases
-
(N. Tavaloni and P. D. Berk, eds.), Raven Press, New York
-
B. Burchell, Molecular biology of the uridine diphosphate glucuronosyltransferases, in Hepatic Transport and Bile Secretion: Physiology and Pathophysiology (N. Tavaloni and P. D. Berk, eds.), Raven Press, New York, 1993, p. 489.
-
(1993)
Hepatic Transport and Bile Secretion: Physiology and Pathophysiology
, pp. 489
-
-
Burchell, B.1
-
36
-
-
0028044817
-
A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, penols, and carboxylic acids
-
M. Pritchard, S. Fournel-Gigleux, G. Siest, P. Mackenzie, and J. Magdalou, A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, penols, and carboxylic acids, Mol. Pharmacol., 45, 42 (1994).
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 42
-
-
Pritchard, M.1
Fournel-Gigleux, S.2
Siest, G.3
Mackenzie, P.4
Magdalou, J.5
-
37
-
-
85102663705
-
4-hydroxyretinoic acid, a novel substrate for human liver UDP-glucuronosyltransferases and recombinant UGT2B7
-
submitted
-
V. M. Samokyszyn, W. E. Gall, G. Zawada, M. A. Freyaldenhoven, G. Chen, and A. Radominska-Pandya, 4-Hydroxyretinoic acid, a novel substrate for human liver UDP-glucuronosyltransferases and recombinant UGT2B7, J. Biol. Chem. (submitted).
-
J. Biol. Chem.
-
-
Samokyszyn, V.M.1
Gall, W.E.2
Zawada, G.3
Freyaldenhoven, M.A.4
Chen, G.5
Radominska-Pandya, A.6
-
38
-
-
0026010397
-
Quantitative structure-activity relationships of the metabolism of drugs by uridine diphosphate glucuronosyltransferase
-
K. H. Kim, Quantitative structure-activity relationships of the metabolism of drugs by uridine diphosphate glucuronosyltransferase, J. Pharm. Sci., 80, 966 (1991).
-
(1991)
J. Pharm. Sci.
, vol.80
, pp. 966
-
-
Kim, K.H.1
-
39
-
-
0028331320
-
Mechanistic studies of uridine diphosphate glucuronosyltransferase
-
H. Yin, G. Bennett, and J. P. Jones, Mechanistic studies of uridine diphosphate glucuronosyltransferase, Chem.-Biol, Interact., 90, 47 (1994).
-
(1994)
Chem.-biol, Interact.
, vol.90
, pp. 47
-
-
Yin, H.1
Bennett, G.2
Jones, J.P.3
-
40
-
-
0025871397
-
Glucuronidation of 3′-azido-3′-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase. Significance of nucleoside hydrophobicity and inhibition by xenobiotics
-
A. Resetar, D. Minick, and T. Spector, Glucuronidation of 3′-azido-3′-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase. Significance of nucleoside hydrophobicity and inhibition by xenobiotics, Biochem. Pharmacol., 42, 559 (1991).
-
(1991)
Biochem. Pharmacol.
, vol.42
, pp. 559
-
-
Resetar, A.1
Minick, D.2
Spector, T.3
-
41
-
-
0024241217
-
Examination of the substrate specificity of cloned rat kidney phenol UDP-glucuronyltransferase expressed in COS-7 cells
-
M.R. Jackson, S. Fournel-Gigleux, D. Harding, and B. Burchell, Examination of the substrate specificity of cloned rat kidney phenol UDP-glucuronyltransferase expressed in COS-7 cells, Mol. Pharmacol., 34, 638 (1988).
-
(1988)
Mol. Pharmacol.
, vol.34
, pp. 638
-
-
Jackson, M.R.1
Fournel-Gigleux, S.2
Harding, D.3
Burchell, B.4
-
42
-
-
0025265006
-
Inhibition of UDP glucuronosyltransferase activity by possible transition state analogues in rat liver microsomes
-
D. Noort, M. W. H. Coughtrie, B. Burchell, G. A. van der Marel, J. H. Van Boom, and G. J. Mulder, Inhibition of UDP glucuronosyltransferase activity by possible transition state analogues in rat liver microsomes, Eur. J. Biochem, 188, 309 (1990).
-
(1990)
Eur. J. Biochem
, vol.188
, pp. 309
-
-
Noort, D.1
Coughtrie, M.W.H.2
Burchell, B.3
Van Der Marel, G.A.4
Van Boom, J.H.5
Mulder, G.J.6
-
43
-
-
0028870462
-
Characterization of a new class of inhibitors of the recombinant human liver UDP-glucuronosyltransferase, UGT1*6
-
E. Battaglia, A. Elass, R. R. Drake, P. Paul, S. Treat, J. Magdalou, S. Fournel-Gigleux, G. Siest, G. Vergoten, R. Lester, and A. Radominska, Characterization of a new class of inhibitors of the recombinant human liver UDP-glucuronosyltransferase, UGT1*6, Biochim. Biophys. Acta, 1243, 9 (1995).
-
(1995)
Biochim. Biophys. Acta
, vol.1243
, pp. 9
-
-
Battaglia, E.1
Elass, A.2
Drake, R.R.3
Paul, P.4
Treat, S.5
Magdalou, J.6
Fournel-Gigleux, S.7
Siest, G.8
Vergoten, G.9
Lester, R.10
Radominska, A.11
-
44
-
-
0028303560
-
Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: Possible involvement of a histidine residue in the catalytic process
-
E. Battaglia, M. Pritchard, M. Ouzzine, S. Fournel-Gigleux, A. Radominska, G. Siest, and J. Magdalou, Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process, Arch. Biochem. Biophys., 309, 266 (1994).
-
(1994)
Arch. Biochem. Biophys.
, vol.309
, pp. 266
-
-
Battaglia, E.1
Pritchard, M.2
Ouzzine, M.3
Fournel-Gigleux, S.4
Radominska, A.5
Siest, G.6
Magdalou, J.7
-
45
-
-
0028360401
-
The chemical modification of human liver UDP-glucuronosyltransferase UGT1*6 reveals the involvement of a carboxyl group in catalysis
-
E. Battaglia, C. Senay, S. Fournel-Gigleux, R. Herber, G. Siest, and J. Magdalou, The chemical modification of human liver UDP-glucuronosyltransferase UGT1*6 reveals the involvement of a carboxyl group in catalysis, FEBS Lett., 309, 266 (1994).
-
(1994)
FEBS Lett.
, vol.309
, pp. 266
-
-
Battaglia, E.1
Senay, C.2
Fournel-Gigleux, S.3
Herber, R.4
Siest, G.5
Magdalou, J.6
-
46
-
-
0030800075
-
Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: Identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue
-
C. P. Strassburg, K. Oldhaffer, M. P. Manns, and R. H. Tukey, Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: Identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue, Mol. Pharmacol., 52, 212 (1997).
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 212
-
-
Strassburg, C.P.1
Oldhaffer, K.2
Manns, M.P.3
Tukey, R.H.4
-
47
-
-
0032502764
-
Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic 1A8
-
C. P. Strassburg, M. P. Manns, and R. H. Tukey, Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic 1A8, J. Biol. Chem., 273, 8719 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8719
-
-
Strassburg, C.P.1
Manns, M.P.2
Tukey, R.H.3
-
48
-
-
0013588037
-
CDNA cloning and characterization of the human UDP glucuronosyltransferase, UGT1A3
-
B. Mojarrabi, R. Butler, and P. I. Mackenzie, cDNA cloning and characterization of the human UDP glucuronosyltransferase, UGT1A3, Biochem. Biophys. Res. Commun., 225, 785 (1996).
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 785
-
-
Mojarrabi, B.1
Butler, R.2
Mackenzie, P.I.3
-
49
-
-
0032529231
-
Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8
-
Z. Cheng, A. Radominska-Pandya, and T. R. Tephly, Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8, Arch. Biochem. Biophys., 356, 301 (1998).
-
(1998)
Arch. Biochem. Biophys.
, vol.356
, pp. 301
-
-
Cheng, Z.1
Radominska-Pandya, A.2
Tephly, T.R.3
-
51
-
-
0027235464
-
Glucuronidation of thyroid hormone by human bilirubin and phenol UDP-glucuronyltransferase isoenzymes
-
T. J. Visser, E. Kaptein, A. L. Gijzel, W. W. de Herder, T. Ebner, and B. Burchell, Glucuronidation of thyroid hormone by human bilirubin and phenol UDP-glucuronyltransferase isoenzymes, FEBS Lett., 324, 358 (1993).
-
(1993)
FEBS Lett.
, vol.324
, pp. 358
-
-
Visser, T.J.1
Kaptein, E.2
Gijzel, A.L.3
De Herder, W.W.4
Ebner, T.5
Burchell, B.6
-
52
-
-
0345368207
-
Glucuronidation of estrogens and retinoic acid by human intestinal microsomes
-
submitted
-
P. Czernik, J. M. Little, G. W. Barone, J.-P. Raufman, and A. Radominska-Pandya, Glucuronidation of estrogens and retinoic acid by human intestinal microsomes, Arch. Biochem. Biophys. (submitted).
-
Arch. Biochem. Biophys.
-
-
Czernik, P.1
Little, J.M.2
Barone, G.W.3
Raufman, J.-P.4
Radominska-Pandya, A.5
-
53
-
-
0344936869
-
-
7th European ISSX Meeting, Budapest
-
A. Radominska-Pandya, A. R. Jude, J. M. Little, A. W. Bull, J. E. Evans, and D. F. Grant, Mono-and di-hydroxylated fatty acid derivatives are novel substrates for human microsomal and recombinant UDP-glucuronosyltransferases, 7th European ISSX Meeting, Budapest, 1999.
-
(1999)
Mono-and Di-hydroxylated Fatty Acid Derivatives Are Novel Substrates for Human Microsomal and Recombinant UDP-glucuronosyltransferases
-
-
Radominska-Pandya, A.1
Jude, A.R.2
Little, J.M.3
Bull, A.W.4
Evans, J.E.5
Grant, D.F.6
-
54
-
-
0027433317
-
Complementary deoxyribonucleic acid cloning and expression of human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs
-
C. Jin, J. O. Miners, K. J. Lillywhite, and P. I. Mackenzie, Complementary deoxyribonucleic acid cloning and expression of human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs, J. Pharm. Exp. Ther., 264, 475 (1993).
-
(1993)
J. Pharm. Exp. Ther.
, vol.264
, pp. 475
-
-
C, J.1
Miners, J.O.2
Lillywhite, K.J.3
Mackenzie, P.I.4
-
55
-
-
0031894377
-
The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)
-
B. L. Coffman, C. D. King, G. R. Rios, and T. R. Tephly, The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268), Drug Metab. Disp., 26, 73 (1998).
-
(1998)
Drug Metab. Disp.
, vol.26
, pp. 73
-
-
Coffman, B.L.1
King, C.D.2
Rios, G.R.3
Tephly, T.R.4
-
56
-
-
0344505984
-
Differential glucuronidation of bile acids, androgens and estrogens by the human recombinant UDP-glucuronosyltransferases UGT1A3 and 2B7
-
in press
-
W. E. Gall, G. Zawada, B. Mojarrabi, T. R. Tephly, M. D. Green, B. L. Coffman, P. I. Mackenzie, and A. Radominska-Pandya, Differential glucuronidation of bile acids, androgens and estrogens by the human recombinant UDP-glucuronosyltransferases UGT1A3 and 2B7, J. Steroid Biochem. Mol. Biol. (in press).
-
J. Steroid Biochem. Mol. Biol.
-
-
Gall, W.E.1
Zawada, G.2
Mojarrabi, B.3
Tephly, T.R.4
Green, M.D.5
Coffman, B.L.6
Mackenzie, P.I.7
Radominska-Pandya, A.8
-
57
-
-
0027267719
-
CDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily
-
C. Jin, J. O. Miners, K. J. Lillywhite, and P. I. Mackenzie, cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily, Biochem. Biophys. Res. Commun., 194, 496 (1993).
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.194
, pp. 496
-
-
Jin, C.1
Miners, J.O.2
Lillywhite, K.J.3
Mackenzie, P.I.4
-
58
-
-
0029809062
-
19 steroids
-
19 steroids, J. Biol. Chem., 271, 22,855 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22855
-
-
Beaulieu, M.1
Levesque, E.2
Hum, D.W.3
Belanger, A.4
-
59
-
-
0020586942
-
Ethynylestradiol-17β D-ring glucuronide conjugates are potent cholestatic agents in the rat
-
M. Vore, H. Hadd, and W. Slikker, Jr., Ethynylestradiol-17β D-ring glucuronide conjugates are potent cholestatic agents in the rat, Life. Sci., 32, 2989 (1983).
-
(1983)
Life. Sci.
, vol.32
, pp. 2989
-
-
Vore, M.1
Hadd, H.2
Slikker W., Jr.3
-
60
-
-
0027242397
-
Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions
-
R. P. Remmel and B. Burchell, Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions, Biochem. Pharmacol., 46, 559 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 559
-
-
Remmel, R.P.1
Burchell, B.2
-
61
-
-
0344505983
-
The effect of carboxyl-linked glucuronides on human microsomal and recombinant UDP-glucuronosyltransferases
-
in press
-
N. Terrier, S. Fournel-Gigleux, J. Magdalou, G. Chen, W. E. Gall, and A. Radominska-Pandya, The effect of carboxyl-linked glucuronides on human microsomal and recombinant UDP-glucuronosyltransferases, Arch. Biochem. Biophys. (in press).
-
Arch. Biochem. Biophys.
-
-
Terrier, N.1
Fournel-Gigleux, S.2
Magdalou, J.3
Chen, G.4
Gall, W.E.5
Radominska-Pandya, A.6
-
62
-
-
0015523047
-
Regulation of microsomal enzymes by phospholipids. V. Kinetic studies of hepatic uridine diphosphate-glucuronyltransferase
-
D. A. Vessey and D. Zakim, Regulation of microsomal enzymes by phospholipids. V. Kinetic studies of hepatic uridine diphosphate-glucuronyltransferase, J. Biol. Chem., 247, 3023 (1972).
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 3023
-
-
Vessey, D.A.1
Zakim, D.2
-
63
-
-
0023146762
-
The enzymatic mechanism of glucuronidation catalyzed by two purified rat liver steroid UDP-glucuronosyltransferases
-
C. N. Falany, M. D. Green, and T. R. Tephly, The enzymatic mechanism of glucuronidation catalyzed by two purified rat liver steroid UDP-glucuronosyltransferases, J. Biol. Chem., 262, 1218 (1987).
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 1218
-
-
Falany, C.N.1
Green, M.D.2
Tephly, T.R.3
-
64
-
-
0021061756
-
Kinetic properties of the rat intestinal microsomal 1-naphthol:UDP-glucuronosyl transferase. Inhibition by UDP and UDP-N-acetylglucosamine
-
A. S. Koster and J. Noordhoek, Kinetic properties of the rat intestinal microsomal 1-naphthol:UDP-glucuronosyl transferase. Inhibition by UDP and UDP-N-acetylglucosamine, Biochim. Biophys. Acta, 761, 76 (1983).
-
(1983)
Biochim. Biophys. Acta
, vol.761
, pp. 76
-
-
Koster, A.S.1
Noordhoek, J.2
-
65
-
-
0015523747
-
A study on the enzymatic mechanism of guinea-pig hepatic-microsomal bilirubin glucuronyl transferase
-
R. F. Potrepka and J. L. Spratt, A study on the enzymatic mechanism of guinea-pig hepatic-microsomal bilirubin glucuronyl transferase, Eur. J. Biochem., 29, 433 (1972).
-
(1972)
Eur. J. Biochem.
, vol.29
, pp. 433
-
-
Potrepka, R.F.1
Spratt, J.L.2
-
66
-
-
0016554213
-
Morphine metabolism. IV. Studies on the mechanism of morphine: Uridine diphosphoglucuronyltransferase and its activation by bilirubin
-
E. Sanchez and T. R. Tephly, Morphine metabolism. IV. Studies on the mechanism of morphine: Uridine diphosphoglucuronyltransferase and its activation by bilirubin, Mol. Pharmacol., 11, 613 (1975).
-
(1975)
Mol. Pharmacol.
, vol.11
, pp. 613
-
-
Sanchez, E.1
Tephly, T.R.2
-
67
-
-
0017106709
-
Kinetics of steroid transport through cell membranes: Comparison of the uptake of cortisol by isolated rat liver cells with binding of cortisol to rat liver cytosol
-
M. L. Rao, G. S. Rao, and H. Breuer, Kinetics of steroid transport through cell membranes: Comparison of the uptake of cortisol by isolated rat liver cells with binding of cortisol to rat liver cytosol, Biochim. Biophys. Acta, 452, 89 (1976).
-
(1976)
Biochim. Biophys. Acta
, vol.452
, pp. 89
-
-
Rao, M.L.1
Rao, G.S.2
Breuer, H.3
-
68
-
-
0020491333
-
Factors modulating the catalytic specificity of a pure form of UDP-glucuronyltransferase
-
J. Magdalou, Y. Hochman, and D. Zakim, Factors modulating the catalytic specificity of a pure form of UDP-glucuronyltransferase, J. Biol. Chem., 257, 13,624 (1982).
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13624
-
-
Magdalou, J.1
Hochman, Y.2
Zakim, D.3
-
69
-
-
0021338808
-
Studies of the catalytic mechanism of microsomal UDP-glucuronyltransferase. Alpha-glucuronidase activity and its stimulation by phospholipids
-
Y. Hochman and D. Zakim, Studies of the catalytic mechanism of microsomal UDP-glucuronyltransferase. Alpha-glucuronidase activity and its stimulation by phospholipids, J. Biol. Chem., 259, 5521 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 5521
-
-
Hochman, Y.1
Zakim, D.2
-
70
-
-
0021112015
-
Evidence for an active site arginine in UDP-glucuronyltransferase
-
D. Zakim, Y. Hochman, and W. C. Kenney, Evidence for an active site arginine in UDP-glucuronyltransferase, J. Biol. Chem., 258, 6430 (1983).
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 6430
-
-
Zakim, D.1
Hochman, Y.2
Kenney, W.C.3
-
71
-
-
0030989680
-
Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid
-
E. Battaglia, S. Nowell, R. R. Drake, J. Magdalou, S. Fournel-Gigleux, C. Senay, and A. Radominska, Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid., Drug Metab. Disp., 25, 406 (1997).
-
(1997)
Drug Metab. Disp.
, vol.25
, pp. 406
-
-
Battaglia, E.1
Nowell, S.2
Drake, R.R.3
Magdalou, J.4
Fournel-Gigleux, S.5
Senay, C.6
Radominska, A.7
-
72
-
-
0027991904
-
Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltrans-ferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation
-
S. B. Senafi, D. J. Clarke, and B. Burchell, Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltrans-ferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation, Biochem. J., 303, 233 (1994).
-
(1994)
Biochem. J.
, vol.303
, pp. 233
-
-
Senafi, S.B.1
Clarke, D.J.2
Burchell, B.3
-
73
-
-
0016853644
-
Commentary: Control of UDP-glucuronyltransferase activity
-
G. J. Dutton, Commentary: Control of UDP-glucuronyltransferase activity, Biochem. Pharmacol., 24, 1835 (1975).
-
(1975)
Biochem. Pharmacol.
, vol.24
, pp. 1835
-
-
Dutton, G.J.1
-
74
-
-
0013958571
-
The competitive inhibition of p-nitrophenyl-beta-D-glucopyranosiduronic acid synthesis by aliphatic alcohols in vitro
-
O. Hanninen and K. Alanen, The competitive inhibition of p-nitrophenyl-beta-D-glucopyranosiduronic acid synthesis by aliphatic alcohols in vitro, Biochem. Pharmacol., 15, 1465 (1966).
-
(1966)
Biochem. Pharmacol.
, vol.15
, pp. 1465
-
-
Hanninen, O.1
Alanen, K.2
-
75
-
-
0018865574
-
Lipophilicity of acceptor substrate as a factor in "late foetal" microsomal UDP-glucuronosyltransferase activity
-
H. P. A. Illing, Lipophilicity of acceptor substrate as a factor in "late foetal" microsomal UDP-glucuronosyltransferase activity, Biochem. Pharmacol., 29, 99 (1980).
-
(1980)
Biochem. Pharmacol.
, vol.29
, pp. 99
-
-
Illing, H.P.A.1
-
76
-
-
0016187530
-
"Coupled transglucuronidation": A new tool for studying the latency of UDP-glucuronyl transferase
-
C. Berry and T. Hallinan, "Coupled transglucuronidation": A new tool for studying the latency of UDP-glucuronyl transferase., FEBS Lett., 42, 73 (1974).
-
(1974)
FEBS Lett.
, vol.42
, pp. 73
-
-
Berry, C.1
Hallinan, T.2
-
77
-
-
0016817805
-
Guinea pig liver microsomal UDP-glucuronyltransferase: Compartmented or phospholipid-constrained
-
C. Berry, A. Stellon, and T. Hallinan, Guinea pig liver microsomal UDP-glucuronyltransferase: Compartmented or phospholipid-constrained, Biochim. Biophys. Acta, 403, 335 (1975).
-
(1975)
Biochim. Biophys. Acta
, vol.403
, pp. 335
-
-
Berry, C.1
Stellon, A.2
Hallinan, T.3
-
78
-
-
0017142383
-
Summary of a novel, three-component regulatory model for uridine diphosphate glucuronyltransferase
-
C. Berry and T. Hallinan, Summary of a novel, three-component regulatory model for uridine diphosphate glucuronyltransferase, Biochem. Soc. Trans., 4, 650 (1976).
-
(1976)
Biochem. Soc. Trans.
, vol.4
, pp. 650
-
-
Berry, C.1
Hallinan, T.2
-
79
-
-
0023923099
-
Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships
-
D. Zakim, M. Cantor, and H. Eibl, Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships, J. Biol. Chem., 263, 5164 (1988).
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5164
-
-
Zakim, D.1
Cantor, M.2
Eibl, H.3
-
80
-
-
84886639236
-
Cloning of cDNAs coding for rat hepatic microsomal UDP-glucuronyltransferases
-
M. R. Jackson, L. R. McCarthy, R. B. Corser, G. C. Barr, and B. Burchell, Cloning of cDNAs coding for rat hepatic microsomal UDP-glucuronyltransferases, Gene, 34, 147 (1985).
-
(1985)
Gene
, vol.34
, pp. 147
-
-
Jackson, M.R.1
McCarthy, L.R.2
Corser, R.B.3
Barr, G.C.4
Burchell, B.5
-
81
-
-
0021205484
-
Cloning and characterization of DNA complementary to rat liver UDP-glucuronosyltransferase mRNA
-
P. I. Mackenzie, F. J. Gonzalez, and I. S. Owens, Cloning and characterization of DNA complementary to rat liver UDP-glucuronosyltransferase mRNA, J. Biol. Chem., 259, 12,153 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 12153
-
-
Mackenzie, P.I.1
Gonzalez, F.J.2
Owens, I.S.3
-
82
-
-
0021765496
-
Cleavage of nascent UDP-glucuronosyltransferase from rat liver by dog pancreatic microsomes
-
P. I. Mackenzie and I. S. Owens, Cleavage of nascent UDP-glucuronosyltransferase from rat liver by dog pancreatic microsomes, Biochem. Biophys. Res. Commun., 122, 1441 (1984).
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 1441
-
-
Mackenzie, P.I.1
Owens, I.S.2
-
83
-
-
0344936868
-
-
IXth International Workshop on Glucuronidation and the UDP-Glucuronosyltransferases
-
M. Ouzzine, J. Magdalou, B. Burchell, and S. Fournel-Gigleux, Targeting and retention of UDP-glucuronosyltransferase into the endoplasmic reticulum, IXth International Workshop on Glucuronidation and the UDP-Glucuronosyltransferases, 1998.
-
(1998)
Targeting and Retention of UDP-glucuronosyltransferase Into the Endoplasmic Reticulum
-
-
Ouzzine, M.1
Magdalou, J.2
Burchell, B.3
Fournel-Gigleux, S.4
-
84
-
-
0023035858
-
Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form
-
P. I. Mackenzie, Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form, J. Biol. Chem., 267, 6119 (1986).
-
(1986)
J. Biol. Chem.
, vol.267
, pp. 6119
-
-
Mackenzie, P.I.1
-
85
-
-
0023655381
-
Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and β-estradiol
-
P. I. Mackenzie, Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and β-estradiol, J. Biol. Chem., 262, 9744 (1987).
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9744
-
-
Mackenzie, P.I.1
-
86
-
-
0023019287
-
Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase
-
T. Iyanagi, M. Haniu, K. Sogawa, Y. Fujii-Kuriyama, S. Watanabe, J. E. Shively, and K. F. Anan, Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase, J. Biol. Chem., 261, 15,607 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 15607
-
-
Iyanagi, T.1
Haniu, M.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
Watanabe, S.5
Shively, J.E.6
Anan, K.F.7
-
87
-
-
0030846868
-
UDP-Glucuronosyltransferase, the role of the amino terminus in dimerization
-
R. Meech and P. I. Mackenzie, UDP-Glucuronosyltransferase, the role of the amino terminus in dimerization, J. Biol. Chem., 272, 26,913 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26913
-
-
Meech, R.1
Mackenzie, P.I.2
-
88
-
-
0029956992
-
Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1
-
R. Meech, G. Yogalingam, and P. Mackenzie, Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1, DNA Cell Biol., 15, 489 (1996).
-
(1996)
DNA Cell Biol.
, vol.15
, pp. 489
-
-
Meech, R.1
Yogalingam, G.2
Mackenzie, P.3
-
89
-
-
0024566868
-
An investigation of the transverse topology of bilirubin UDP-glucuronosyltransferase in rat hepatic endoplasmic reticulum
-
S. R. P. Shepherd, S. J. Baird, T. Hallinan, and B. Burchell, An investigation of the transverse topology of bilirubin UDP-glucuronosyltransferase in rat hepatic endoplasmic reticulum, Biochem. J., 259, 617 (1989).
-
(1989)
Biochem. J.
, vol.259
, pp. 617
-
-
Shepherd, S.R.P.1
Baird, S.J.2
Hallinan, T.3
Burchell, B.4
-
90
-
-
0023909231
-
Topology and regulation of bilirubin UDP-glucuronosyltransferase in sealed native microsomes from rat liver
-
F. Vanstapel and N. Blanckaert, Topology and regulation of bilirubin UDP-glucuronosyltransferase in sealed native microsomes from rat liver, Arch. Biochem. Biophys., 263, 216 (1988).
-
(1988)
Arch. Biochem. Biophys.
, vol.263
, pp. 216
-
-
Vanstapel, F.1
Blanckaert, N.2
-
91
-
-
0026699309
-
Topological disposition of UDP-glucuronyltransferase in rat liver microsomes
-
H. Yokota, A. Yuasa, and R. Sato, Topological disposition of UDP-glucuronyltransferase in rat liver microsomes, J. Biochem., 112, 192 (1992).
-
(1992)
J. Biochem.
, vol.112
, pp. 192
-
-
Yokota, H.1
Yuasa, A.2
Sato, R.3
-
92
-
-
0021430832
-
Cell-free translation of mouse liver mRNA coding for two forms of UDP glucuronosyltransferase
-
P. I. Mackenzie, F. J. Gonzalez, and I. S. Owens, Cell-free translation of mouse liver mRNA coding for two forms of UDP glucuronosyltransferase, Arch. Biochem. Biophys., 230, 676 (1984).
-
(1984)
Arch. Biochem. Biophys.
, vol.230
, pp. 676
-
-
Mackenzie, P.I.1
Gonzalez, F.J.2
Owens, I.S.3
-
93
-
-
0031010059
-
Protein-protein interactions between UDP-glucuronosyltransferase isozymes in rat hepatic microsomes
-
S. Ikushiro, Y. Emi, and T. Iyanagi, Protein-protein interactions between UDP-glucuronosyltransferase isozymes in rat hepatic microsomes, Biochemistry, 36, 7154 (1997).
-
(1997)
Biochemistry
, vol.36
, pp. 7154
-
-
Ikushiro, S.1
Emi, Y.2
Iyanagi, T.3
-
94
-
-
0345368206
-
-
IXth International Workshop on Glucuronidation and UDP-Glucuronosyltransferases
-
S. Ikushiro, Y. Emi, S. Kimura, and T. Iyanagi, Complex formation between UDP-glucuronosyltransferase isozymes in rat hepatic microsomes, IXth International Workshop on Glucuronidation and UDP-Glucuronosyltransferases, 1998.
-
(1998)
Complex Formation between UDP-glucuronosyltransferase Isozymes in Rat Hepatic Microsomes
-
-
Ikushiro, S.1
Emi, Y.2
Kimura, S.3
Iyanagi, T.4
-
95
-
-
0028116221
-
Radiation inactivation analysis of microsomal UDP-glucuronosyltransferases catalysing mono-and diglucuronide formation of 3,6-dihydroxybenzo(a)pyrene and 3,6-dihydroxychrysene
-
H. Gschaidmeier and K. W. Bock, Radiation inactivation analysis of microsomal UDP-glucuronosyltransferases catalysing mono-and diglucuronide formation of 3,6-dihydroxybenzo(a)pyrene and 3,6-dihydroxychrysene, Biochem. Pharmacol., 48, 545 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 545
-
-
Gschaidmeier, H.1
Bock, K.W.2
-
96
-
-
0021133988
-
The molecular weights of UDP-glucuronyltransferase determined with radiation-inactivation analysis. A molecular model of bilirubin UDP-glucuronyltransferase
-
W. H. Peters, P. L. Jansen, and H. Nauta, The molecular weights of UDP-glucuronyltransferase determined with radiation-inactivation analysis. A molecular model of bilirubin UDP-glucuronyltransferase, J. Biol. Chem., 259, 11,701 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 11701
-
-
Peters, W.H.1
Jansen, P.L.2
Nauta, H.3
-
97
-
-
0024521003
-
In situ structural analysis of microsomal UDP-glucuronyltransferases by radiation inactivation
-
D. A. Vessey and E. S. Kempner, In situ structural analysis of microsomal UDP-glucuronyltransferases by radiation inactivation, J. Biol. Chem., 264, 6334 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 6334
-
-
Vessey, D.A.1
Kempner, E.S.2
-
98
-
-
0028873814
-
Mechanism of stimulation of microsomal UDP-glucuronosyltransferase by UDP-N-acetylglucusamine
-
X. Bossuyt and N. Blanckaert, Mechanism of stimulation of microsomal UDP-glucuronosyltransferase by UDP-N-acetylglucusamine, Biochem. J., 305, 321 (1995).
-
(1995)
Biochem. J.
, vol.305
, pp. 321
-
-
Bossuyt, X.1
Blanckaert, N.2
-
99
-
-
0029913593
-
Uridine diphosphoxylose enhances hepatic microsomal UDP-glucuronic glucuronosyltransferase activity by stimulating transport of UDP-glucuronic acid across the endoplasmic reticulum membrane
-
X. Bossuyt and N. Blanckaert, Uridine diphosphoxylose enhances hepatic microsomal UDP-glucuronic glucuronosyltransferase activity by stimulating transport of UDP-glucuronic acid across the endoplasmic reticulum membrane, Biochem. J., 315, 189 (1996).
-
(1996)
Biochem. J.
, vol.315
, pp. 189
-
-
Bossuyt, X.1
Blanckaert, N.2
-
100
-
-
0027935783
-
Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent ATP-dependent transport across the canlicular membrane
-
G. Jedlitschky, I. Leier, M. Bohme, U. Buchholz, J. Bar-Tana, and D. Keppler, Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent ATP-dependent transport across the canlicular membrane, Biochem. Pharmacol., 48, 1113 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1113
-
-
Jedlitschky, G.1
Leier, I.2
Bohme, M.3
Buchholz, U.4
Bar-Tana, J.5
Keppler, D.6
-
101
-
-
0030668526
-
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2
-
G. Jedlitschky, I. Leier, U. Buchholz, J. Hummel-Eisenbeiss, B. Burchell, and D. Keppler, ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2, Biochem. J., 327, 305 (1997).
-
(1997)
Biochem. J.
, vol.327
, pp. 305
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Hummel-Eisenbeiss, J.4
Burchell, B.5
Keppler, D.6
-
102
-
-
0030063480
-
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
-
G. Jedlitschky, I. Leier, U. Buchholz, K. Barnouin, G. Kurz, and D. Keppler, Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump, Cancer Res., 56, 988 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 988
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Barnouin, K.4
Kurz, G.5
Keppler, D.6
-
103
-
-
0029986408
-
Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome
-
J. Kartenbeck, U. Leuschner, R. Mayer, and D. Keppler, Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome, Hepatology, 23, 1061 (1996).
-
(1996)
Hepatology
, vol.23
, pp. 1061
-
-
Kartenbeck, J.1
Leuschner, U.2
Mayer, R.3
Keppler, D.4
-
104
-
-
0031715907
-
Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump
-
G. Bartosz, J. Konig, D. Keppler, and W. Hagmann, Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump, Biol. Chem., 379, 1121 (1998).
-
(1998)
Biol. Chem.
, vol.379
, pp. 1121
-
-
Bartosz, G.1
Konig, J.2
Keppler, D.3
Hagmann, W.4
-
105
-
-
0031758818
-
Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B
-
A. T. Nies, T. Cantz, M. Brom, I. Leier, and D. Keppler, Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B, Hepatology, 28, 1332 (1998).
-
(1998)
Hepatology
, vol.28
, pp. 1332
-
-
Nies, A.T.1
Cantz, T.2
Brom, M.3
Leier, I.4
Keppler, D.5
-
106
-
-
0029862844
-
Evidence for an UDP-glucuronic acid/phenol glucuronide antiport in rat liver microsomal vesicles
-
G. Banhegyi, L. Braun, P. Marcolongo, M. Csala, R. Fulceri, J. Mandl, and A. Benedetti, Evidence for an UDP-glucuronic acid/phenol glucuronide antiport in rat liver microsomal vesicles, Biochem. J., 315, 171 (1996).
-
(1996)
Biochem. J.
, vol.315
, pp. 171
-
-
Banhegyi, G.1
Braun, L.2
Marcolongo, P.3
Csala, M.4
Fulceri, R.5
Mandl, J.6
Benedetti, A.7
-
107
-
-
0344074794
-
-
IXth International Workshop on Glucuronidation and UDP-Glucuronosyltransferases
-
A. Miyoshi, K. Tsuruda, M. Tsuda, Y. Nagamatsu, S. Marsuoka, K. Yoshisue, M. Shimizudani-Tanaka, Y. Ishii, S. Ohgiya, and K. Oguri, cDNA cloning of UGT2B21 and UGT2B22 in guinea pig liver, and an active UGT for morphine 6-glucuronidation express by the hereo-oligomer, IXth International Workshop on Glucuronidation and UDP-Glucuronosyltransferases, 1998.
-
(1998)
CDNA Cloning of UGT2B21 and UGT2B22 in Guinea Pig Liver, and An Active UGT for Morphine 6-glucuronidation Express by the Hereo-oligomer
-
-
Miyoshi, A.1
Tsuruda, K.2
Tsuda, M.3
Nagamatsu, Y.4
Marsuoka, S.5
Yoshisue, K.6
Shimizudani-Tanaka, M.7
Ishii, Y.8
Ohgiya, S.9
Oguri, K.10
-
108
-
-
0344505981
-
-
Halstead Press, New York
-
S. Bazaes, E. Cardemil, J. Churchich, H. Cid, J. Eyzaguirre, R. Kemp, T. Nowak, H. J. Schaffer, E. Silva, and J. Wilson, Chemical Modification of Enzymes: Active-Site Studies, Halstead Press, New York, 1987.
-
(1987)
Chemical Modification of Enzymes: Active-site Studies
-
-
Bazaes, S.1
Cardemil, E.2
Churchich, J.3
Cid, H.4
Eyzaguirre, J.5
Kemp, R.6
Nowak, T.7
Schaffer, H.J.8
Silva, E.9
Wilson, J.10
-
109
-
-
0019879365
-
Modification of functional arginine residues in purified bovine testicular hyaluronidase with butane-2,3-dione
-
P. Gacesa, M. J. Savitsky, K. S. Dodgson, and A. H. Olavesen, Modification of functional arginine residues in purified bovine testicular hyaluronidase with butane-2,3-dione, Biochim. Biophys. Acta, 661, 205 (1981).
-
(1981)
Biochim. Biophys. Acta
, vol.661
, pp. 205
-
-
Gacesa, P.1
Savitsky, M.J.2
Dodgson, K.S.3
Olavesen, A.H.4
-
110
-
-
0021262685
-
Specific inactivation of the phosphohydrolase component of the hepatic microsomal glucose-6-phosphatase system by diethyl pyrocarbonate
-
W. J. Arion, B. Burchell, and A. Burchell, Specific inactivation of the phosphohydrolase component of the hepatic microsomal glucose-6-phosphatase system by diethyl pyrocarbonate, Biochem. J., 220, 342 (1984).
-
(1984)
Biochem. J.
, vol.220
, pp. 342
-
-
Arion, W.J.1
Burchell, B.2
Burchell, A.3
-
111
-
-
0032522255
-
Bilirubin is an effective antioxidant of peroxynitrite-mediated protein oxidation in human blood plasma
-
M. Minetti, C. Mallozzi, A. M. Di Stasi, and D. Pietraforte, Bilirubin is an effective antioxidant of peroxynitrite-mediated protein oxidation in human blood plasma, Arch. Biochem. Biophys., 352, 165 (1998).
-
(1998)
Arch. Biochem. Biophys.
, vol.352
, pp. 165
-
-
Minetti, M.1
Mallozzi, C.2
Di Stasi, A.M.3
Pietraforte, D.4
-
112
-
-
0022922683
-
Inhibition of bilirubin UDP glucuronosyltransferase activity by triphenylacetic acid and related compounds
-
S. Fournel, B. Gregoire, J. Magdalou, M. C. Carre, C. Lafaurie, G. Siest, and P. Caubere, Inhibition of bilirubin UDP glucuronosyltransferase activity by triphenylacetic acid and related compounds, Biochim. Biophys. Acta, 883, 190 (1986).
-
(1986)
Biochim. Biophys. Acta
, vol.883
, pp. 190
-
-
Fournel, S.1
Gregoire, B.2
Magdalou, J.3
Carre, M.C.4
Lafaurie, C.5
Siest, G.6
Caubere, P.7
-
113
-
-
0024418428
-
Novel inhibitors and substrates of bilirubin UDP-glucuronosyltransferase: Arylalkylcarboxylic acids
-
S. Fournel-Gigleux, S. R. P. Shepherd, M. C. Carre, B. Burchell, G. Siest, and P. Caubere, Novel inhibitors and substrates of bilirubin UDP-glucuronosyltransferase: arylalkylcarboxylic acids, Eur. J. Biochem., 183, 653 (1989).
-
(1989)
Eur. J. Biochem.
, vol.183
, pp. 653
-
-
Fournel-Gigleux, S.1
Shepherd, S.R.P.2
Carre, M.C.3
Burchell, B.4
Siest, G.5
Caubere, P.6
-
114
-
-
0344074793
-
Design of inhibitors of UDP-glucuronosyltransferase chemically related to arylcarboxylic acids
-
(K. W. Bock, W. Gerok, S. Matern, and R. Schmid, eds.), Kluwer Academic, Dordrecht
-
T. Pillot, E. Battaglia, M. Said, J. C. Ziegler, S. Fournel-Gigleux, A. Cartier, J. Magdalou, and G. Siest, Design of inhibitors of UDP-glucuronosyltransferase chemically related to arylcarboxylic acids., in Hepatic Metabolism and Disposition of Endo-and Xenobiotics (K. W. Bock, W. Gerok, S. Matern, and R. Schmid, eds.), Kluwer Academic, Dordrecht, 1991, p. 161.
-
(1991)
Hepatic Metabolism and Disposition of Endo-and Xenobiotics
, pp. 161
-
-
Pillot, T.1
Battaglia, E.2
Said, M.3
Ziegler, J.C.4
Fournel-Gigleux, S.5
Cartier, A.6
Magdalou, J.7
Siest, G.8
-
115
-
-
0031606456
-
Mechanism of inhibition of rat liver bilirubin UDP-glucuronosyltransferase by triphenylalkyl derivatives
-
M. Said, E. Battaglia, E. Abdelaziz, V. Cano, J. C. Ziegler, A. Cartier, M. H. Livertoux, G. Vergoten, S. Fournel-Gigleux, and J. Magdalou, Mechanism of inhibition of rat liver bilirubin UDP-glucuronosyltransferase by triphenylalkyl derivatives, J. Biochem. Mol. Toxicol, 12, 19 (1998).
-
(1998)
J. Biochem. Mol. Toxicol
, vol.12
, pp. 19
-
-
Said, M.1
Battaglia, E.2
Abdelaziz, E.3
Cano, V.4
Ziegler, J.C.5
Cartier, A.6
Livertoux, M.H.7
Vergoten, G.8
Fournel-Gigleux, S.9
Magdalou, J.10
-
116
-
-
0029853289
-
Inhibition of bilirubin UDP-glucuronosyltransferase: A comparative molecular field analysis (CoMFA)
-
M. Said, A. Elass, J. C. Ziegler, B. Vergoten, and J. Magdalou, Inhibition of bilirubin UDP-glucuronosyltransferase: A comparative molecular field analysis (CoMFA), Quant. Structure Activity Relation, 15, 382 (1996).
-
(1996)
Quant. Structure Activity Relation
, vol.15
, pp. 382
-
-
Said, M.1
Elass, A.2
Ziegler, J.C.3
Vergoten, B.4
Magdalou, J.5
-
117
-
-
0030957158
-
Synthesis and inhibitory effect of a trisubstrate transition state analog for UDP-glucuronosyltransferases
-
C. M. Timmers, M. Dekker, R. C. Buijman, G. A. van der Marel, B. Ethell, G. Anderson, B. Burchell, G. J. Mulder, and J. H. van Boom, Synthesis and inhibitory effect of a trisubstrate transition state analog for UDP-glucuronosyltransferases, Bioorg. Med. Chem. Lett., 7, 1501 (1997).
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 1501
-
-
Timmers, C.M.1
Dekker, M.2
Buijman, R.C.3
Van Der Marel, G.A.4
Ethell, B.5
Anderson, G.6
Burchell, B.7
Mulder, G.J.8
Van Boom, J.H.9
-
118
-
-
0026009190
-
Selective inhibition of glucuronidation by 2,2,2-triphenylethyl UDP in isolated rat hepatocytes
-
D. Noort, E. A. Meijer, T. J. Visser, J. H. N. Meerman, G. A. van der Marel, J. H. van Boom, and G. J. Mulder, Selective inhibition of glucuronidation by 2,2,2-triphenylethyl UDP in isolated rat hepatocytes, Mol. Pharmacol., 40, 316 (1991).
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 316
-
-
Noort, D.1
Meijer, E.A.2
Visser, T.J.3
Meerman, J.H.N.4
Van Der Marel, G.A.5
Van Boom, J.H.6
Mulder, G.J.7
-
119
-
-
0026705819
-
Selective and potent inhibition of different hepatic UDP-glucuronosyltransferase activities by ω,ω,ω-triphenylalcohols and UDP derivatives
-
M. Said, D. Noort, J. Magdalou, J. C. Ziegler, G. A. van der Marel, J. H. van Boom, G. J. Mulder, and G. Siest, Selective and potent inhibition of different hepatic UDP-glucuronosyltransferase activities by ω,ω,ω-triphenylalcohols and UDP derivatives, Biochem. Biophys. Res. Commun., 187, 140 (1992).
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.187
, pp. 140
-
-
Said, M.1
Noort, D.2
Magdalou, J.3
Ziegler, J.C.4
Van Der Marel, G.A.5
Van Boom, J.H.6
Mulder, G.J.7
Siest, G.8
-
120
-
-
0028349889
-
Photoaffinity labeling for evaluation of uridinyl analogs as specific inhibitors of rat liver microsomal UDP-glucuronosyltransferases
-
A. Radominska, P. Paul, S. Treat, H. Towbin, C. Pratt, J. Little, J. Magdalou, R. Lester, and R. R. Drake, Photoaffinity labeling for evaluation of uridinyl analogs as specific inhibitors of rat liver microsomal UDP-glucuronosyltransferases, Biochim. Biophys. Acta, 1205, 336 (1994).
-
(1994)
Biochim. Biophys. Acta
, vol.1205
, pp. 336
-
-
Radominska, A.1
Paul, P.2
Treat, S.3
Towbin, H.4
Pratt, C.5
Little, J.6
Magdalou, J.7
Lester, R.8
Drake, R.R.9
-
121
-
-
0029000317
-
Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs
-
J. M. Little, R. R. Drake, R. Vonk, F. Kuipers, R. Lester, and A. Radominska, Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs, J. Pharmacol. Exp. Ther., 273, 1551 (1995).
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.273
, pp. 1551
-
-
Little, J.M.1
Drake, R.R.2
Vonk, R.3
Kuipers, F.4
Lester, R.5
Radominska, A.6
-
122
-
-
0032031994
-
Inhibition of UDP-glucuronosyltransferase by 5′-O-amino acid and oligopeptide derivatives of uridine: Structure-activity relationships
-
Z. G. Naydenova, K. C. Grancharov, D. K. Alargov, E. V. Golovinsky, I. M. Stanoeva, L. D. Shalamanova, and I. K. Pajeva, Inhibition of UDP-glucuronosyltransferase by 5′-O-amino acid and oligopeptide derivatives of uridine: Structure-activity relationships, Z. Naturforsch., 53, 173 (1998).
-
(1998)
Z. Naturforsch.
, vol.53
, pp. 173
-
-
Naydenova, Z.G.1
Grancharov, K.C.2
Alargov, D.K.3
Golovinsky, E.V.4
Stanoeva, I.M.5
Shalamanova, L.D.6
Pajeva, I.K.7
-
123
-
-
0029593658
-
Inhibition of UDP-glucuronyltransferase activity in rat liver microsomes by pyrimidine derivatives
-
Z. Naydenova, K. Grancharov, M. Shopova, and E. Golovinsky, Inhibition of UDP-glucuronyltransferase activity in rat liver microsomes by pyrimidine derivatives, Compar. Biochem. Physiol., 112C, 321 (1995).
-
(1995)
Compar. Biochem. Physiol.
, vol.112 C
, pp. 321
-
-
Naydenova, Z.1
Grancharov, K.2
Shopova, M.3
Golovinsky, E.4
-
124
-
-
0343488688
-
Monometoxytrityl derivatives of uridine as inhibitors of a human recombinant UDP-glucuronosyltransferase: UGT*6
-
V. Cano, C. Lorentz, J. Magdalou, V. Loppinet, G. Siest, and J. C. Ziegler, Monometoxytrityl derivatives of uridine as inhibitors of a human recombinant UDP-glucuronosyltransferase: UGT*6, Life Sci., 6, PL1 (1997).
-
(1997)
Life Sci.
, vol.6 PL1
-
-
Cano, V.1
Lorentz, C.2
Magdalou, J.3
Loppinet, V.4
Siest, G.5
Ziegler, J.C.6
-
125
-
-
0032476086
-
Inhibitory effects of uridine diphosphate on UDP-glucuronosyltransferase
-
H. Yokota, F. Ando, H. Iwano, and A. Yuasa, Inhibitory effects of uridine diphosphate on UDP-glucuronosyltransferase, Life Sci., 63, 1693 (1998).
-
(1998)
Life Sci.
, vol.63
, pp. 1693
-
-
Yokota, H.1
Ando, F.2
Iwano, H.3
Yuasa, A.4
-
126
-
-
0029981211
-
Enzyme inhibition in open systems. Superiority of uncompetitive agents
-
A. M. Westley and J. Westley, Enzyme inhibition in open systems. Superiority of uncompetitive agents, J. Biol. Chem., 271, 5347 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5347
-
-
Westley, A.M.1
Westley, J.2
-
127
-
-
0031688282
-
Enzymatic transition states and transition state analog design
-
V. L. Schramm, Enzymatic transition states and transition state analog design, Annu. Rev. Biochem., 67, 693 (1998).
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 693
-
-
Schramm, V.L.1
-
128
-
-
0028287938
-
Transition state analysis and inhibitor design for enzymatic reactions
-
V. L. Schramm, Transition state analysis and inhibitor design for enzymatic reactions, J. Biol. Chem., 269, 18,259 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18259
-
-
Schramm, V.L.1
-
129
-
-
0023137126
-
Isolation and purification of two human liver UDP-glucuronosyltransferases
-
Y. M. Irshaid and T. R. Tephly, Isolation and purification of two human liver UDP-glucuronosyltransferases, Mol. Pharmacol., 31, 21 (1987).
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 21
-
-
Irshaid, Y.M.1
Tephly, T.R.2
-
130
-
-
0025824215
-
Isolation and characterization of hyodeoxycholic acid:UDP-glucuronosyltransferase from human liver
-
H. Matern, N. Lappas, and S. Matern, Isolation and characterization of hyodeoxycholic acid:UDP-glucuronosyltransferase from human liver, Eur. J. Biochem., 200, 393 (1991).
-
(1991)
Eur. J. Biochem.
, vol.200
, pp. 393
-
-
Matern, H.1
Lappas, N.2
Matern, S.3
-
131
-
-
0026756613
-
Photoaffinity labeling of glycosyltransferases
-
R. R. Drake and A. D. Elbein, Photoaffinity labeling of glycosyltransferases, Glycobiology, 2, 279 (1992).
-
(1992)
Glycobiology
, vol.2
, pp. 279
-
-
Drake, R.R.1
Elbein, A.D.2
-
132
-
-
0028203281
-
Synthesis and uses of azido-nucleoside diphosphate sugar photoaffinity analogs
-
A. Radominska and R. Drake, Synthesis and uses of azido-nucleoside diphosphate sugar photoaffinity analogs, Methods Enzymol., 230, 330 (1994).
-
(1994)
Methods Enzymol.
, vol.230
, pp. 330
-
-
Radominska, A.1
Drake, R.2
-
133
-
-
0022400351
-
Furosemide 1-o-acyl glucuronide. In vitro biosynthesis and pH-dependent isomerization to β-glucuronidase-resistant forms
-
A. Rachmel, G. A. Hazelton, A. L. Yergey, and D. J. Liberate, Furosemide 1-O-acyl glucuronide. In vitro biosynthesis and pH-dependent isomerization to β-glucuronidase-resistant forms, Drug Metab. Disp., 13, 705 (1985).
-
(1985)
Drug Metab. Disp.
, vol.13
, pp. 705
-
-
Rachmel, A.1
Hazelton, G.A.2
Yergey, A.L.3
Liberate, D.J.4
-
134
-
-
0026327990
-
Radominska, synthesis and characterization of 5-azido-UDP-glucuronic acid. A new photoaffinity probe for UDP-glucuronic acid-utilizing proteins
-
R. R. Drake, P. Zimniak, B. E. Haley, R. Lester, A. D. Elbein, and A. Radominska, Synthesis and characterization of 5-azido-UDP-glucuronic acid. A new photoaffinity probe for UDP-glucuronic acid-utilizing proteins, J. Biol. Chem., 266, 23,257 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 23257
-
-
Drake, R.R.1
Zimniak, P.2
Haley, B.E.3
Lester, R.4
Elbein, A.D.5
-
135
-
-
0000811210
-
Purification, photoaffinity labeling and properties of plant UDP-glucose: Phosphoryldolichol glucosyltransferase
-
R. R. Drake, G. P. Kaushal, I. Pastuszak, and A. D. Elbein, Purification, photoaffinity labeling and properties of plant UDP-glucose: Phosphoryldolichol glucosyltransferase, Plant Physiol., 97, 396 (1991).
-
(1991)
Plant Physiol.
, vol.97
, pp. 396
-
-
Drake, R.R.1
Kaushal, G.P.2
Pastuszak, I.3
Elbein, A.D.4
-
136
-
-
0028314103
-
Bile acid glucuronidation by rat liver microsomes and cDNA-expressed UDP-glucuronosyltransferases
-
A. Radominska, J. M. Little, R. Lester, and P. I. Mackenzie, Bile acid glucuronidation by rat liver microsomes and cDNA-expressed UDP-glucuronosyltransferases, Biochim. Biophys. Acta, 1205, 75 (1994).
-
(1994)
Biochim. Biophys. Acta
, vol.1205
, pp. 75
-
-
Radominska, A.1
Little, J.M.2
Lester, R.3
Mackenzie, P.I.4
-
137
-
-
0028036952
-
Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs
-
A. Radominska, C. Berg, S. Treat, J. M. Little, J. Gollan, R. Lester, and R. Drake, Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs, Biochim. Biophys. Acta, 1195, 63 (1994).
-
(1994)
Biochim. Biophys. Acta
, vol.1195
, pp. 63
-
-
Radominska, A.1
Berg, C.2
Treat, S.3
Little, J.M.4
Gollan, J.5
Lester, R.6
Drake, R.7
-
138
-
-
0024381187
-
Synthesis and properties of 5-azido-UDP-glucose: Development of photoaffinity probes for nucleotide diphospate sugar binding sites
-
R. R. Drake, R. K. Evans, M. J. Wolf, and B. E. Haley, Synthesis and properties of 5-azido-UDP-glucose: Development of photoaffinity probes for nucleotide diphospate sugar binding sites, J. Biol. Chem., 264, 11,928 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 11928
-
-
Drake, R.R.1
Evans, R.K.2
Wolf, M.J.3
Haley, B.E.4
-
139
-
-
0027451740
-
Purification and characterization of a catalytically active human liver UDP-glucuronosyltransferase expressed as a fusion protein
-
E. coli
-
T. Pillot, M. Ouzzine, S. Fournel-Gigleux, C. LaFaurie, A. Radominska, R. Lester, R. Drake, S. Treat, G. Siest, and J. Magdalou, Purification and characterization of a catalytically active human liver UDP-glucuronosyltransferase expressed as a fusion protein in E. coli, Biochem. Biophys. Res. Commun., 196, 473 (1993).
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.196
, pp. 473
-
-
Pillot, T.1
Ouzzine, M.2
Fournel-Gigleux, S.3
Lafaurie, C.4
Radominska, A.5
Lester, R.6
Drake, R.7
Treat, S.8
Siest, G.9
Magdalou, J.10
-
140
-
-
0026349175
-
Nucleotide photoaffinity labeling of protein kinase subunits
-
B. E. Haley, Nucleotide photoaffinity labeling of protein kinase subunits, Methods Emzymol., 200, 477 (1991).
-
(1991)
Methods Emzymol.
, vol.200
, pp. 477
-
-
Haley, B.E.1
-
141
-
-
0026667310
-
Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucuronosyltransferases
-
R. Drake, I. Igari, R. Lester, A. Elbein, and A. Radominska, Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucuronosyltransferases, J. Biol. Chem., 267, 11,360 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11360
-
-
Drake, R.1
Igari, I.2
Lester, R.3
Elbein, A.4
Radominska, A.5
-
142
-
-
0031843966
-
Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase UGT1A6
-
E. Battaglia, N. Terrier, M. Mizeracka, C. Senay, J. Magdalou, S. Fournel-Gigleux, and A. Radominska, Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase UGT1A6., Drug Metab. Disp., 26, 812 (1998).
-
(1998)
Drug Metab. Disp.
, vol.26
, pp. 812
-
-
Battaglia, E.1
Terrier, N.2
Mizeracka, M.3
Senay, C.4
Magdalou, J.5
Fournel-Gigleux, S.6
Radominska, A.7
-
143
-
-
0031021739
-
Glucuronidation of all trans-retinoic acid and 5,6-epoxy-all trans-retinoic acid: Activation of rat liver microsomal UDP-glucuronosyltranferase activity by alamethicin
-
J. M. Little, P. A. Lehman, S. Nowell, V. Samokyszyn, and A. Radominska, Glucuronidation of all trans-retinoic acid and 5,6-epoxy-all trans-retinoic acid: Activation of rat liver microsomal UDP-glucuronosyltranferase activity by alamethicin, Drug Metab. Disp., 25, 5 (1997).
-
(1997)
Drug Metab. Disp.
, vol.25
, pp. 5
-
-
Little, J.M.1
Lehman, P.A.2
Nowell, S.3
Samokyszyn, V.4
Radominska, A.5
-
144
-
-
0030872541
-
Glucuronidation of retinoids by rat recombinant UDP-glucuronosyltransferase 1.1 (bilirubin UGT1)
-
A. Radominska, J. M. Little, P. A. Lehman, V. Samokyszyn, G. R. Rios, C. D. King, M. D. Green, and T. R. Tephly, Glucuronidation of retinoids by rat recombinant UDP-glucuronosyltransferase 1.1 (bilirubin UGT1), Drug Metab. Disp., 25, 889 (1997).
-
(1997)
Drug Metab. Disp.
, vol.25
, pp. 889
-
-
Radominska, A.1
Little, J.M.2
Lehman, P.A.3
Samokyszyn, V.4
Rios, G.R.5
King, C.D.6
Green, M.D.7
Tephly, T.R.8
-
145
-
-
0344505956
-
Synthesis and characterization of a new fluorescent photoaffinity probe, 7-azido-4-methylcoumarin. Application to labeling the aglycon binding site of human liver recombinant UGT1A6
-
in press
-
C. Senay, E. Battaglia, S. Fournel-Gigleux, J. Magdalou, and A. Radominska-Pandya, Synthesis and characterization of a new fluorescent photoaffinity probe, 7-azido-4-methylcoumarin. Application to labeling the aglycon binding site of human liver recombinant UGT1A6, Arch. Biochem. Biophys. (in press).
-
Arch. Biochem. Biophys.
-
-
Senay, C.1
Battaglia, E.2
Fournel-Gigleux, S.3
Magdalou, J.4
Radominska-Pandya, A.5
-
146
-
-
0015164611
-
Excretion in dog bile of glucose and xylose conjugates of bilirubin
-
Fevery, G. P. Van Hees, P. Leroy, F. Compernolle, and K. P. M. Heirwegh, Excretion in dog bile of glucose and xylose conjugates of bilirubin, Biochem. J., 125, 929 (1971).
-
(1971)
Biochem. J.
, vol.125
, pp. 929
-
-
Fevery1
Van Hees, G.P.2
Leroy, P.3
Compernolle, F.4
Heirwegh, K.P.M.5
-
147
-
-
0015171336
-
Formation of bilirubin glucoside
-
K. P. Wong, Formation of bilirubin glucoside, Biochem. J., 125, 929 (1971).
-
(1971)
Biochem. J.
, vol.125
, pp. 929
-
-
Wong, K.P.1
-
148
-
-
0021225545
-
Bilirubin mono-and di-glucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronyltransferase
-
B. Burchell and N. Blanckaert, Bilirubin mono-and di-glucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronyltransferase, Biochem. J., 223, 461 (1984).
-
(1984)
Biochem. J.
, vol.223
, pp. 461
-
-
Burchell, B.1
Blanckaert, N.2
-
149
-
-
0027292087
-
A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-0-glucosides of bile acids in human liver microsomes
-
A. Radominska, J. M. Little, R. Drake, Y. Igari, S. Fournel-Gigleux, J. Magdalou, B. Burchell, A. Elbein, G. Siest, and R. Lester, A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-0-glucosides of bile acids in human liver microsomes, J. Biol. Chem., 268, 15,127 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15127
-
-
Radominska, A.1
Little, J.M.2
Drake, R.3
Igari, Y.4
Fournel-Gigleux, S.5
Magdalou, J.6
Burchell, B.7
Elbein, A.8
Siest, G.9
Lester, R.10
-
150
-
-
0015584212
-
Studies of mammalian glucoside conjugation
-
T. Gessner, A. Jacknowitz, and C. A. Vollmer, Studies of mammalian glucoside conjugation, Biochem. J., 132, 249 (1973).
-
(1973)
Biochem. J.
, vol.132
, pp. 249
-
-
Gessner, T.1
Jacknowitz, A.2
Vollmer, C.A.3
-
151
-
-
0020094818
-
Bile acid and bile salt disrupt gastric mucosal barrier in the dog by different mechanisms
-
W. C. Duane, D. M. Wiegand, and C. E. Sievert, Bile acid and bile salt disrupt gastric mucosal barrier in the dog by different mechanisms, Am. J. Physiol., 242, G95 (1982).
-
(1982)
Am. J. Physiol.
, vol.242
-
-
Duane, W.C.1
Wiegand, D.M.2
Sievert, C.E.3
-
152
-
-
0022529717
-
Induction of UDP-glucuronyl transferase mRNA in embryonic chick livers by phenobarbital
-
M. R. Jackson, S. M. Kennedy, G. Lown, and B. Burchell, Induction of UDP-glucuronyl transferase mRNA in embryonic chick livers by phenobarbital, Biochem. Pharmacol., 35, 1191 (1986).
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 1191
-
-
Jackson, M.R.1
Kennedy, S.M.2
Lown, G.3
Burchell, B.4
-
153
-
-
0023031991
-
Rat liver UDP-glucuronosyltransferase. CDNA sequence and expression of a form glucuronidating 3-hydroxyandrogens
-
P. I. Mackenzie, Rat liver UDP-glucuronosyltransferase. cDNA sequence and expression of a form glucuronidating 3-hydroxyandrogens, J. Biol. Chem., 261, 14,112 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 14112
-
-
Mackenzie, P.I.1
-
154
-
-
0000614010
-
Enzymatic oxidation of undine diphosphate glucose to uridine diphosphate glucuronic acid
-
J. L. Strominger, H. M. Kalckar, J. Axelrod, and E. S. Maxwell, Enzymatic oxidation of undine diphosphate glucose to uridine diphosphate glucuronic acid, J. Am. Chem. Soc., 76, 6411 (1954).
-
(1954)
J. Am. Chem. Soc.
, vol.76
, pp. 6411
-
-
Strominger, J.L.1
Kalckar, H.M.2
Axelrod, J.3
Maxwell, E.S.4
-
155
-
-
0023763078
-
A membrane transporter mediates access of uridine 5′-diphosphoglucuronic acid from the cytosol into the endoplasmic reticulum of rat hepatocytes: Implications for glucuronidation reaction
-
S. C. Hauser, J. C. Ziurys, and J. L. Gollan, A membrane transporter mediates access of uridine 5′-diphosphoglucuronic acid from the cytosol into the endoplasmic reticulum of rat hepatocytes: Implications for glucuronidation reaction, Biochim. Biophys. Acta, 967, 149 (1988).
-
(1988)
Biochim. Biophys. Acta
, vol.967
, pp. 149
-
-
Hauser, S.C.1
Ziurys, J.C.2
Gollan, J.L.3
-
156
-
-
0026517062
-
New developments in glucuronidation research: Report of a workshop on "glucuronidation, its role in health and disease,"
-
P. L. M. Jansen, G. J. Mulder, and B. Burchell, New developments in glucuronidation research: Report of a workshop on "Glucuronidation, Its Role in Health and Disease," Hepatology, 15, 532 (1992).
-
(1992)
Hepatology
, vol.15
, pp. 532
-
-
Jansen, P.L.M.1
Mulder, G.J.2
Burchell, B.3
-
157
-
-
0028796027
-
Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles
-
C. Berg, A. Radominska, R. Lester, and J. Gollan, Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles, Gastroenterology, 108, 183-192 (1995).
-
(1995)
Gastroenterology
, vol.108
, pp. 183192
-
-
Berg, C.1
Radominska, A.2
Lester, R.3
Gollan, J.4
-
158
-
-
0030568864
-
Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum
-
E. Battaglia, S. Nowell, R. R. Drake, M. Mizeracka, C. L. Berg, J. Magdalou, S. Fournel-Gigleux, J. L. Gollan, R. Lester, and A. Radominska, Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum, Biochim. Biophys. Acta, 1283, 223 (1996).
-
(1996)
Biochim. Biophys. Acta
, vol.1283
, pp. 223
-
-
Battaglia, E.1
Nowell, S.2
Drake, R.R.3
Mizeracka, M.4
Berg, C.L.5
Magdalou, J.6
Fournel-Gigleux, S.7
Gollan, J.L.8
Lester, R.9
Radominska, A.10
-
159
-
-
0027216130
-
Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases
-
P. Paul, T. Lutz, C. Osborn, S. Kyosseva, A. Elbein, H. Towbin. A. Radominska, and R. Drake, Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases, J. Biol. Chem., 268, 12,933 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12933
-
-
Paul, P.1
Lutz, T.2
Osborn, C.3
Kyosseva, S.4
Elbein, A.5
Towbin, H.6
Radominska, A.7
Drake, R.8
-
160
-
-
0023904909
-
Biosynthesis of hydroxyl-linked glucuronides of short-chain bile acids by rat liver 3-hydroxysteroid UDP-glucuronosyltransferase
-
A. Radominska, M. D. Green, P. Zimniak, and R. Lester, Biosynthesis of hydroxyl-linked glucuronides of short-chain bile acids by rat liver 3-hydroxysteroid UDP-glucuronosyltransferase, J. Lipid Res., 29, 501 (1988).
-
(1988)
J. Lipid Res.
, vol.29
, pp. 501
-
-
Radominska, A.1
Green, M.D.2
Zimniak, P.3
Lester, R.4
-
161
-
-
0032488649
-
A functional role for histidyl residues of the UDP-glucuronic acid carrier in rat endoplasmic reticulum membranes
-
E. Battaglia and A. Radominska-Pandya, A functional role for histidyl residues of the UDP-glucuronic acid carrier in rat endoplasmic reticulum
-
(1998)
Biochemistry
, vol.37
, pp. 258
-
-
Battaglia, E.1
Radominska-Pandya, A.2
-
162
-
-
8544224973
-
The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
P. I. Mackenzie, I. S. Owens, B. Burchell, K. W. Bock, A. Bairoch, A. Belanger, S. Fournel-Gigleux, M. Green, D. W. Hum, T. Iyanagi, et al., The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence, Pharmacogenetics, 7, 255 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255
-
-
Mackenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
Fournel-Gigleux, S.7
Green, M.8
Hum, D.W.9
Iyanagi, T.10
-
163
-
-
0026644417
-
Functional expression of zeaxanthin glucosyltransferase from Erwinia herbicola and a proposed uridine diphosphate binding site
-
B. S. Bundle, D. A. O'Brien, M. Alberti, P. Beyer, and J. E. Hearst, Functional expression of zeaxanthin glucosyltransferase from Erwinia herbicola and a proposed uridine diphosphate binding site, Proc. Natl. Acad. Sci. USA, 89, 9321 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9321
-
-
Bundle, B.S.1
O'Brien, D.A.2
Alberti, M.3
Beyer, P.4
Hearst, J.E.5
-
164
-
-
0025236448
-
Expression of chimeric cDNAs in cell culture defines a region of UDP, glucuronosyltransferase involved in substrate selection
-
P. I. Mackenzie, Expression of chimeric cDNAs in cell culture defines a region of UDP, glucuronosyltransferase involved in substrate selection, J. Biol. Chem., 265, 3432 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 3432
-
-
Mackenzie, P.I.1
-
165
-
-
0027749498
-
Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaftinity labeling of fusion proteins
-
T. Pillot, M. Ouzzine, S. Fournel-Gigleux, C. LaFaurie, D. Tebbi, S. Treat, A. Radominska, R. Lester, G. Siest, and J. Magdalou, Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaftinity labeling of fusion proteins, Biochem. Biophys. Res. Commun, 197, 785 (1993).
-
(1993)
Biochem. Biophys. Res. Commun
, vol.197
, pp. 785
-
-
Pillot, T.1
Ouzzine, M.2
Fournel-Gigleux, S.3
LaFaurie, C.4
D Tebbi, S.T.5
Radominska, A.6
Lester, R.7
Siest, G.8
Magdalou, J.9
-
166
-
-
0029884743
-
Proteolytic mapping of the thymidine/thymidylate binding site of herpes simplex virus type 1 thymidine kinase: A general photoaffinity labeling method for identifying active-site peptides
-
T. M. Rechtin, M. E. Black, and R. R. Drake, Proteolytic mapping of the thymidine/thymidylate binding site of herpes simplex virus type 1 thymidine kinase: A general photoaffinity labeling method for identifying active-site peptides, Anal. Biochem., 237, 135 (1996).
-
(1996)
Anal. Biochem.
, vol.237
, pp. 135
-
-
Rechtin, T.M.1
Black, M.E.2
Drake, R.R.3
-
167
-
-
0020696906
-
Affinity labeling of purine nucleotide sites in proteins
-
R. F. Colman, Affinity labeling of purine nucleotide sites in proteins, Anna. Rev. Biochem., 52, 67 (1983).
-
(1983)
Anna. Rev. Biochem.
, vol.52
, pp. 67
-
-
Colman, R.F.1
-
168
-
-
0020485888
-
Interactions between the mitochondrial adenosinetriphosphatase and periodate-oxidized adenosine 5′-triphosphate, an affinity label for adenosine 5′-triphosphate binding sites
-
P. N. Lowe and R. B. Beechey, Interactions between the mitochondrial adenosinetriphosphatase and periodate-oxidized adenosine 5′-triphosphate, an affinity label for adenosine 5′-triphosphate binding sites, Biochemistry, 21, 4073 (1982).
-
(1982)
Biochemistry
, vol.21
, pp. 4073
-
-
Lowe, P.N.1
Beechey, R.B.2
-
169
-
-
0028805697
-
Identification of the active sites of human and schistosomal hypoxanthine-guanine phosphoribosyltransferases by GMP-2′,3′-dialdehyde affinity labeling
-
J. Kanaani, D. Maltby, P. Focia, and C. C. Wang, Identification of the active sites of human and schistosomal hypoxanthine-guanine phosphoribosyltransferases by GMP-2′,3′-dialdehyde affinity labeling, Biochemistry, 34, 14,987 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 14987
-
-
Kanaani, J.1
Maltby, D.2
Focia, P.3
Wang, C.C.4
-
170
-
-
0022005917
-
Inhibition of hyaluronate synthesis
-
P. Prehm, Inhibition of hyaluronate synthesis, Biochem. J., 225, 699 (1985).
-
(1985)
Biochem. J.
, vol.225
, pp. 699
-
-
Prehm, P.1
-
171
-
-
0026051566
-
Modification of the ATP inhibitory site of the Ascaris suun phosphofructokinase results in the stabilization of an inactive T state
-
G. S. J. Rao, P. F. Cook, and B. G. Harris, Modification of the ATP inhibitory site of the Ascaris suun phosphofructokinase results in the stabilization of an inactive T state, Biochemistry, 30, 9998 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 9998
-
-
Rao, G.S.J.1
Cook, P.F.2
Harris, B.G.3
-
172
-
-
0029132172
-
Inactivation of escherichia coli phosphoribosylpyrophosphate synthetase by the 2′,3′-dialdehyde derivative of ATP
-
I. Hilden, B. Hove-Jensen, and K. W. Harlow, Inactivation of Escherichia coli phosphoribosylpyrophosphate synthetase by the 2′,3′-dialdehyde derivative of ATP, J. Biol. Chem., 270, 20,730 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20730
-
-
Hilden, I.1
Hove-Jensen, B.2
Harlow, K.W.3
-
173
-
-
0001036382
-
Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells
-
D. Harding, S. Fournel-Gigleux, M. R. Jackson, and B. Burchell, Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells, Proc. Natl. Acad. Sci. USA, 85, 8381 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8381
-
-
Harding, D.1
Fournel-Gigleux, S.2
Jackson, M.R.3
Burchell, B.4
-
174
-
-
0027530118
-
Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family
-
T. Ebner and B. Burchell, Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family, Drug Metab. Disp., 21, 50 (1993).
-
(1993)
Drug Metab. Disp.
, vol.21
, pp. 50
-
-
Ebner, T.1
Burchell, B.2
-
175
-
-
0028888943
-
Photoaffinity labeling of retinoic acid-binding proteins
-
P. S. Bernstein, S.-Y. Choi, Y.-C. Ho, and R. R. Rando, Photoaffinity labeling of retinoic acid-binding proteins, Proc. Natl. Acad. Sci. USA, 92, 654 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 654
-
-
Bernstein, P.S.1
Choi, S.-Y.2
Ho, Y.-C.3
Rando, R.R.4
-
176
-
-
0031584094
-
3H]all trans-retenoic acid to characterization of rat liver microsomal UP-glucuronosyltransferase(s) with activity toward retinoic acid
-
3H]all trans-retenoic acid to characterization of rat liver microsomal UP-glucuronosyltransferase(s) with activity toward retinoic acid, Biochem. Biophys. Res. Commun., 230, 497 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.230
, pp. 497
-
-
Little, J.M.1
Radominska, A.2
-
178
-
-
0029113143
-
Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A
-
J. E. Wedekind, P. A. Frey, and I. Rayment, Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A. Biochemistry, 34, 11,049 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 11049
-
-
Wedekind, J.E.1
Frey, P.A.2
Rayment, I.3
-
179
-
-
0029895408
-
The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): Cloning, characterization, and assignment to human chromosome 4, band q26
-
A. Bosio, E. Binczek, M. M. Lebeau, A. A. Fernald, and W. Stoffel, The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): Cloning, characterization, and assignment to human chromosome 4, band q26, Genomics, 34, 69 (1996).
-
(1996)
Genomics
, vol.34
, pp. 69
-
-
Bosio, A.1
Binczek, E.2
Lebeau, M.M.3
Fernald, A.A.4
Stoffel, W.5
-
180
-
-
0024003767
-
Sequence of three bronze alleles of maize and correlation with the genetic fine structure
-
E. J. Ralston, J. J. English, and H. K. Dooner, Sequence of three bronze alleles of maize and correlation with the genetic fine structure, Genetics, 119, 55 (1988).
-
(1988)
Genetics
, vol.119
, pp. 55
-
-
Ralston, E.J.1
English, J.J.2
Dooner, H.K.3
-
181
-
-
0028086144
-
The complete DNA sequence of Autographa californica nuclear polyhedrosis virus
-
M. D. Ayres, S. C. Howard, J. Kuzio, M. Lopez-Ferber, and R. D. Possee, The complete DNA sequence of Autographa californica nuclear polyhedrosis virus, Virology, 202, 586 (1994).
-
(1994)
Virology
, vol.202
, pp. 586
-
-
Ayres, M.D.1
Howard, S.C.2
Kuzio, J.3
Lopez-Ferber, M.4
Possee, R.D.5
-
182
-
-
0025719224
-
Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics
-
G. Jenkins and E. Cundliffe, Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics, Gene, 108, 55 (1991).
-
(1991)
Gene
, vol.108
, pp. 55
-
-
Jenkins, G.1
Cundliffe, E.2
-
183
-
-
0344505955
-
-
12th International Symposium on Microsomes and Drug Oxidations, Montpellier
-
S. Dubois, M. Beaulieu, É. Lévesque, C. Albert, D. W. Hum, and A. Bélanger, Residue 121 is involved in the specificity of the UGT2B17 steroid metabolizing enzyme, 12th International Symposium on Microsomes and Drug Oxidations, Montpellier, 1998.
-
(1998)
Residue 121 Is Involved in the Specificity of the UGT2B17 Steroid Metabolizing Enzyme
-
-
Dubois, S.1
Beaulieu, M.2
Lévesque, E.3
Albert, C.4
Hum, D.W.5
Bélanger, A.6
-
184
-
-
0032513046
-
Localization and functional analysis of the substrate specificity/catalytic domains of human M-form and P-form phenol sulfotransferases
-
Y. Sakakibara, Y. Takami, T. Nakayama, M. Suiko, and M. C. Liu, Localization and functional analysis of the substrate specificity/catalytic domains of human M-form and P-form phenol sulfotransferases, J. Biol. Chem., 273, 6242 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6242
-
-
Sakakibara, Y.1
Takami, Y.2
Nakayama, T.3
Suiko, M.4
Liu, M.C.5
-
185
-
-
0032437886
-
A single amino acid, glu 146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3
-
R. Dajani, A. M. Hood, and M. W. H. Coughtrie, A single amino acid, glu 146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3, Mol. Pharmacol., 54, 942 (1998).
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 942
-
-
Dajani, R.1
Hood, A.M.2
Coughtrie, M.W.H.3
-
186
-
-
0027326717
-
Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's
-
K. G. Ravichandran, S. S. Boddupalli, C. A. Hasermann, J. A. Peterson, and J. Deisenhofer, Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's, Science, 261, 731 (1993).
-
(1993)
Science
, vol.261
, pp. 731
-
-
Ravichandran, K.G.1
Boddupalli, S.S.2
Hasermann, C.A.3
Peterson, J.A.4
Deisenhofer, J.5
-
187
-
-
0030443993
-
Computer modeling of 3D structures of cytochrome P450s
-
Y. Chang, O. Stiffelman, and G. Loew, Computer modeling of 3D structures of cytochrome P450s, Biochimie, 78, 771 (1996).
-
(1996)
Biochimie
, vol.78
, pp. 771
-
-
Chang, Y.1
Stiffelman, O.2
Loew, G.3
-
188
-
-
0028774713
-
Crystal structure of cellular retinoic acid binding proteins I and II in complex with all-trans-retinoic acid and a synthetic retinoid
-
G. J. Kleywegt, T. Bergfors, H. Senn, P. LeMotte, B. Gsell, K. Shudo, and T. A. Jone, Crystal structure of cellular retinoic acid binding proteins I and II in complex with all-trans-retinoic acid and a synthetic retinoid, Structure, 2, 1241 (1994).
-
(1994)
Structure
, vol.2
, pp. 1241
-
-
Kleywegt, G.J.1
Bergfors, T.2
Senn, H.3
LeMotte, P.4
Gsell, B.5
Shudo, K.6
Jone, T.A.7
-
189
-
-
44949272730
-
A time-efficient, linear-space local similarity algorithm
-
X. Huang and W. Miller, A time-efficient, linear-space local similarity algorithm, Adv. Appl. Math., 12, 337 (1991).
-
(1991)
Adv. Appl. Math.
, vol.12
, pp. 337
-
-
Huang, X.1
Miller, W.2
-
190
-
-
0025861217
-
Cloning and stable expression of a new member of the human liver phenol/bilirubin:UDP-glucuronosyltransferase cDNA family
-
R. Wooster, L. Sutherland, T. Ebner, D. Clarke, O. da Cruz e Silva, and B. Burchell, Cloning and stable expression of a new member of the human liver phenol/bilirubin:UDP-glucuronosyltransferase cDNA family, Biochem. J., 278, 465 (1991).
-
(1991)
Biochem. J.
, vol.278
, pp. 465
-
-
Wooster, R.1
Sutherland, L.2
Ebner, T.3
Clarke, D.4
Da Cruz E Silva, O.5
Burchell, B.6
-
191
-
-
0027469416
-
Sequence analysis and expression of the cDNA for the phenol-sulfating form of human liver phenol sulfotransferase
-
T. W. Wilborn, K. A. Comer, T. P. Dooley, I. M. Reardon, R. L. Heinrikson, and C. N. Falany, Sequence analysis and expression of the cDNA for the phenol-sulfating form of human liver phenol sulfotransferase, Mol. Pharmacol., 43, 70 (1993).
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 70
-
-
Wilborn, T.W.1
Comer, K.A.2
Dooley, T.P.3
Reardon, I.M.4
Heinrikson, R.L.5
Falany, C.N.6
-
194
-
-
0026775534
-
Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluoreneinduced hepatocarcinogenesis
-
T. Yerokun, J. L. Etheredge, T. R. Norton, H. A. Carter, K. H. Chung, P. J. Birckbichler, and D. P. Ringer, Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluoreneinduced hepatocarcinogenesis, Cancer Res., 52, 4779 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 4779
-
-
Yerokun, T.1
Etheredge, J.L.2
Norton, T.R.3
Carter, H.A.4
Chung, K.H.5
Birckbichler, P.J.6
Ringer, D.P.7
-
195
-
-
0029122101
-
Characterization and prevalence of a polymorphism in the 3′ untranslated region of cytochrome P4501Al in cancer-prone Atlantic tomcod
-
N. K. Roy, G. L. Kreamer, B. Konkle, C. Grunwald, and I. Wirgin, Characterization and prevalence of a polymorphism in the 3′ untranslated region of cytochrome P4501Al in cancer-prone Atlantic tomcod, Arch. Biochem. Biophys., 322, 204 (1995).
-
(1995)
Arch. Biochem. Biophys.
, vol.322
, pp. 204
-
-
Roy, N.K.1
Kreamer, G.L.2
Konkle, B.3
Grunwald, C.4
Wirgin, I.5
-
196
-
-
0031752608
-
Molecular cloning and functional analysis of cynomolgus monkey CYP1a2
-
Sakuma, M. Hieda, T. Igarashi, S. Ohgiya, R. Nagata, N. Nemoto, and T. Kamataki, Molecular cloning and functional analysis of cynomolgus monkey CYP1A2, Biochem. Pharmacol., 56, 131 (1998).
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 131
-
-
Hieda, M.1
Igarashi, T.2
Ohgiya, S.3
Nagata, R.4
Nemoto, N.5
Kamataki, T.6
-
197
-
-
0025022689
-
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
-
S. Yamano, J. Tatsuno, and F. J. Gonzalez, The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes, Biochemistry, 29, 1322 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 1322
-
-
Yamano, S.1
Tatsuno, J.2
Gonzalez, F.J.3
-
198
-
-
0025763625
-
Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily
-
J. A. Goldstein, J. L. Raucy, J. A. Blaisdell, M. B. Faletto, and M. Romkes, Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily, Biochemistry, 30, 3247 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 3247
-
-
Goldstein, J.A.1
Raucy, J.L.2
Blaisdell, J.A.3
Faletto, M.B.4
Romkes, M.5
-
199
-
-
0019775835
-
The sequence of human serum albumin cDNA and its expression in
-
R. M. Lawn, J. Adelman, S. C. Bock, A. E. Franke, C. M. Houck, R. C. Najarian, P. H. Seeburg, and K. L. Wion, The sequence of human serum albumin cDNA and its expression in E. coli., Nucleic Acids Res., 9, 6103 (1981).
-
(1981)
E. Coli., Nucleic Acids Res.
, vol.9
, pp. 6103
-
-
Lawn, R.M.1
Adelman, J.2
Bock, S.C.3
Franke, A.E.4
Houck, C.M.5
Najarian, R.C.6
Seeburg, P.H.7
Wion, K.L.8
-
200
-
-
0041725049
-
The structure and function of the UDP-glucuronosyltransferase gene family
-
B. Burchell, C. H. Brierley, G. Managhan, and D. J. Clarke, The structure and function of the UDP-glucuronosyltransferase gene family, Adv. Pharmacol., 42, 335-338 (1998).
-
(1998)
Adv. Pharmacol.
, vol.42
, pp. 335-338
-
-
Burchell, B.1
Brierley, C.H.2
Managhan, G.3
Clarke, D.J.4
-
201
-
-
0031784886
-
Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7
-
Z. Cheng, G. R. Rios, C. D. King, B. L. Coffman, M. D. Green, B. Mojarrabi, P. I. Mackenzie, and T. R. Tephly, Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7, Toxicol. Sci., 45, 52 (1998).
-
(1998)
Toxicol. Sci.
, vol.45
, pp. 52
-
-
Cheng, Z.1
Rios, G.R.2
King, C.D.3
Coffman, B.L.4
Green, M.D.5
Mojarrabi, B.6
Mackenzie, P.I.7
Tephly, T.R.8
-
202
-
-
0029962074
-
Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein
-
M. D. Green and T. R. Tephly, Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein, Drug Metab. Disp., 24, 356 (1996).
-
(1996)
Drug Metab. Disp.
, vol.24
, pp. 356
-
-
Green, M.D.1
Tephly, T.R.2
-
203
-
-
0026058319
-
Stable expression of two human UDP-glucuronosyltransferases cDNAs in V79 cell cultures
-
S. Fournel-Gigleux, L. Sutherland, N. Sabolovic, B. Burchell, and G. Siest, Stable expression of two human UDP-glucuronosyltransferases cDNAs in V79 cell cultures, Mol. Pharmacol., 39, 177 (1991).
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 177
-
-
Fournel-Gigleux, S.1
Sutherland, L.2
Sabolovic, N.3
Burchell, B.4
Siest, G.5
-
204
-
-
0031570313
-
The regio-and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11
-
C.-J. Jin, P. I. Mackenzie, and J. O. Miners, The regio-and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11, Arch. Biochem. Biophy., 341, 207 (1997).
-
(1997)
Arch. Biochem. Biophy.
, vol.341
, pp. 207
-
-
Jin, C.-J.1
Mackenzie, P.I.2
Miners, J.O.3
-
205
-
-
0025321169
-
Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells
-
J. K. Ritter, Y. Y. Sheen, and I. S. Owens, Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells, J. Biol. Chem., 265, 7900 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 7900
-
-
Ritter, J.K.1
Sheen, Y.Y.2
Owens, I.S.3
-
206
-
-
0344784391
-
Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11
-
M. Beaulieu, E. Lévesque, D. W. Hum, and A. Belanger, Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11, Biochem. Biophys. Res. Commun., 248, 44 (1998).
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 44
-
-
Beaulieu, M.1
Lévesque, E.2
Hum, D.W.3
A Belanger4
-
207
-
-
0028031001
-
Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates
-
M. D. Green, E. M. Oturu, and T. R. Tephly, Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates, Drug Metab. Disp., 22, 799 (1994).
-
(1994)
Drug Metab. Disp.
, vol.22
, pp. 799
-
-
Green, M.D.1
Oturu, E.M.2
Tephly, T.R.3
-
208
-
-
0030795936
-
85): A UDP-glucuronosyltransferase encoded by a polymorphic gene
-
85): A UDP-glucuronosyltransferase encoded by a polymorphic gene, Pharmacogeneticv, 7, 317 (1997).
-
(1997)
Pharmacogeneticv
, vol.7
, pp. 317
-
-
Lévesque, E.1
Beaulieu, M.2
Green, M.D.3
Tephly, T.R.4
Bélanger, A.5
Hum, D.W.6
-
209
-
-
0031765698
-
Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3
-
M. D. Green, C. D. King, B. Mojarrabi, P. I. Mackenzie, and T. R. Tephly, Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3, Drug Metab. Disp., 26, 507 (1998).
-
(1998)
Drug Metab. Disp.
, vol.26
, pp. 507
-
-
Green, M.D.1
King, C.D.2
Mojarrabi, B.3
Mackenzie, P.I.4
Tephly, T.R.5
-
210
-
-
0030699360
-
Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: Pharmacological implications
-
M. Ciotti, A. Marrone, C. Potter, and I. S. Owens, Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: Pharmacological implications, Pharmacogenetics, 7, 485 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 485
-
-
Ciotti, M.1
Marrone, A.2
Potter, C.3
Owens, I.S.4
-
211
-
-
0001019366
-
Glucuronidation of 2-amino-1-methyl-6-phenylimidazo|4,5-b|pyridine (PhIP) by human microsomal proteins: Identification of the UGT1A isoforms involved
-
S. Nowell, J. Massengill, S. Williams, A. Radominska-Pandya, T. R. Tephly, Z. Cheng, C. P. Strassburg, R. H. Tukey, S. L. MacLeod, N. P. Lang, and F. F. Kadlubar, Glucuronidation of 2-amino-1-methyl-6-phenylimidazo|4,5-b|pyridine (PhIP) by human microsomal proteins: Identification of the UGT1A isoforms involved, Carcinogenesis, 20, 101 (1999).
-
(1999)
Carcinogenesis
, vol.20
, pp. 101
-
-
Nowell, S.1
Massengill, J.2
Williams, S.3
Radominska-Pandya, A.4
Tephly, T.R.5
Cheng, Z.6
Strassburg, C.P.7
Tukey, R.H.8
MacLeod, S.L.9
Lang, N.P.10
Kadlubar, F.F.11
-
212
-
-
0027484631
-
Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-glucuronosyltransferases stably expressed in tissue culture cell lines
-
R. Wooster, T. Ebner, L. Sutherland, D. Clarke, and B. Burchell, Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-glucuronosyltransferases stably expressed in tissue culture cell lines, Toxicology, 82, 119 (1993).
-
(1993)
Toxicology
, vol.82
, pp. 119
-
-
Wooster, R.1
Ebner, T.2
Sutherland, L.3
Clarke, D.4
Burchell, B.5
-
213
-
-
0031590285
-
The human UDP glucuronosyltransferase, UGT1A10, glucuronidates mycophenolic acid
-
B. Mojarrabi and P. I. Mackenzie, The human UDP glucuronosyltransferase, UGT1A10, glucuronidates mycophenolic acid, Biochem. Biophys. Res. Commun., 238, 775 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 775
-
-
Mojarrabi, B.1
Mackenzie, P.I.2
|