Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia

Biochemical and Biophysical Research Communications

Volumn 292, Issue 2, 2002, Pages 492-497

  Sugatani, Junko ^a   Yamakawa, Kasumi ^a   Yoshinari, Kouich ^a   Miwa, Masao ^a   Machida, Takashi ^b   Takagi, Hitoshi ^b   Mori, Masatomo ^b   Kakizaki, Satoru ^c   Sueyoshi, Tatsuya ^c   Negishi, Masahiko ^c  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Bilirubin; Constitutive active receptor (CAR); Gilbert s syndrome; Hyperbilirubinemia; Phenobarbital responsive enhancer module (PBREM); Single nucleotide polymorphism (SNP); UDP glucuronosyltransferase; UGT1A1

Indexed keywords

BILIRUBIN; GLUCURONOSYLTRANSFERASE; GUANINE; LUCIFERASE; NUCLEOTIDE; THYMINE;

ADOLESCENT; ADULT; AGED; ARTICLE; BILIRUBIN BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ENHANCER REGION; ENZYMATIC ASSAY; ENZYME ACTIVITY; EXON; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GILBERT DISEASE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERBILIRUBINEMIA; MALE; MUTATIONAL ANALYSIS; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TATA BOX; TRANSCRIPTION REGULATION;

EID: 18444399926     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6683     Document Type: Article

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