Neuropeptide Y receptors as targets for anti-obesity drug development: Perspective and current status

European Journal of Pharmacology

Volumn 440, Issue 2-3, 2002, Pages 173-187

  Parker, Eric ^a,b   Van Heek, Margaret ^a   Stamford, Andrew ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Schering Plough Research Institute 2015 Galloping Hill Road ^*  (United States)

Author keywords

Anti obesity agent; Neuropeptide receptor; Neuropeptide Y; Obesity

Indexed keywords

1 NAPHTHALENESULFONIC ACID [4 [(4 AMINO 2 QUINAZOLINYLAMINO)METHYL]CYCLOHEXYLMETHYL]AMIDE; 2 [1 (3 CHLORO 5 ISOPROPOXYCARBONYLAMINOPHENYL)ETHYLAMINO] 6 [2 (5 ETHYL 4 METHYL 2 THIAZOLYL)ETHYL] 4 MORPHOLINOPYRIDINE; AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; ANTIOBESITY AGENT; CP 671906; J 104870; L 152804; LEPTIN; LY 357897; MELANOCORTIN RECEPTOR; N [2 [1,2 DIHYDRO 3,5(4H) DIOXO 1,2 DIPHENYL 1,2,4 TRIAZOL 4 YL]ETHYL] N2 [[1 [2 [4 [5,11 DIHYDRO 6(6H) OXODIBENZ[B,E]AZEPIN 11 YL] 1 PIPERAZINYL] 2 OXOETHYL]CYCLOPENTYL]ACETYL]ARGININAMIDE; N2 DIPHENYLACETYL N (4 UREIDOMETHYLBENZYL)ARGININAMIDE; NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR AGONIST; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR; NEUROPEPTIDE Y2 RECEPTOR; NEUROPEPTIDE Y3 RECEPTOR; NEUROPEPTIDE Y4 RECEPTOR; NEUROPEPTIDE Y5 RECEPTOR; NEUROPEPTIDE Y6 RECEPTOR; PEPTIDE YY; UNCLASSIFIED DRUG;

ARCUATE NUCLEUS; ARTICLE; BRAIN REGION; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENERGY EXPENDITURE; FOOD INTAKE; HOMEOSTASIS; HUMAN; NERVE CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-OBESITY AGENTS; ARGININE; BODY WEIGHT; ENERGY METABOLISM; HUMANS; NEUROPEPTIDE Y; OBESITY; PHARMACEUTICAL PREPARATIONS; RECEPTORS, NEUROPEPTIDE Y; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037066612     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01427-9     Document Type: Article

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