Design, synthesis and SAR of a series of 2-substituted 4-amino-quinazoline neuropeptide Y Y5 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 11, 2000, Pages 1175-1179

  Rueeger, Heinrich ^a   Rigollier, Pascal ^a   Yamaguchi, Yasuchika ^a   Schmidlin, Tibur ^a   Schilling, Walter ^a   Criscione, Leoluca ^a   Whitebread, Steven ^a   Chiesi, Michele ^a   Walker, Mary W ^b   Dhanoa, Dale ^b   Islam, Imadul ^b   Zhang, Jack ^b   Gluchowski, Charles ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y5 RECEPTOR; QUINAZOLINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CHEMISTRY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; FOOD INTAKE; MINING; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; MODELS, MOLECULAR; QUINAZOLINES; RECEPTORS, NEUROPEPTIDE Y; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034608473     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00177-3     Document Type: Article

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