The novel neuropeptide YY1 receptor antagonist J-104870: A potent feeding suppressant with oral bioavailability

Biochemical and Biophysical Research Communications

Volumn 266, Issue 1, 1999, Pages 88-91

  Kanatani, Akio ^a   Kanno, Tetsuya ^a   Ishihara, Akane ^a   Hata, Mikiko ^a   Sakuraba, Aya ^a   Tanaka, Takeshi ^a   Tsuchiya, Yoshimi ^a   Mase, Toshiaki ^a   Fukuroda, Takahiro ^a   Fukami, Takehiro ^a   Ihara, Masaki ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANOREXIGENIC AGENT; BRAIN RECEPTOR; CALCIUM ION; J 104870; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; CARBAMIC ACID DERIVATIVE; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y Y1 RECEPTOR; NEUROPEPTIDE Y-Y1 RECEPTOR; THIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN MEMBRANE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG PENETRATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; FEEDING BEHAVIOR; FOOD INTAKE; HYPOTHALAMUS; ISOTOPE LABELING; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; ANIMAL; BINDING COMPETITION; BIOAVAILABILITY; BRAIN; CELL MEMBRANE; CHO CELL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; HAMSTER; HIPPOCAMPUS; HUMAN; IC 50; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; ORAL DRUG ADMINISTRATION; SPRAGUE DAWLEY RAT; TIME; ZUCKER RAT;

ANIMALIA;

ADMINISTRATION, ORAL; ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL AVAILABILITY; BRAIN; CARBAMATES; CELL MEMBRANE; CHO CELLS; CRICETINAE; FEEDING BEHAVIOR; HIPPOCAMPUS; HUMANS; INHIBITORY CONCENTRATION 50; INJECTIONS, INTRAVENTRICULAR; MALE; NEUROPEPTIDE Y; RATS; RATS, SPRAGUE-DAWLEY; RATS, ZUCKER; RECEPTORS, NEUROPEPTIDE Y; THIAZOLES; TIME FACTORS;

EID: 17544393094     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.1750     Document Type: Article

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