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Volumn 868, Issue 1, 2000, Pages 79-87

Behavioral characterization of neuropeptide Y knockout mice

Author keywords

Acoustic startle; Anxiety; Fasting; Knockout; Nociception; NPY

Indexed keywords

1 (3 METHOXYPHENYL) 1 (4 PHENYLPIPERAZIN 1 YL) 4 METHYL CYCLOHEXANE; [4 [(4 AMINO QUINAZOLIN 2 YLAMINO) METHYL] CYCLOHEXYLMETHYL] AMIDE; AMG 68; CGP 7163A; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR; NEUROPEPTIDE Y5 RECEPTOR; UNCLASSIFIED DRUG;

EID: 0034674684     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02285-X     Document Type: Article
Times cited : (256)

References (35)
  • 1
    • 0026562952 scopus 로고
    • Chronic and continuous intracerebroventricular infusion of neuropeptide Y in Long-Evans rats mimics the feeding behavior of obese Zucker rats
    • Beck B., Stricker K.A., Nicolas J.P., Burlet C. Chronic and continuous intracerebroventricular infusion of neuropeptide Y in Long-Evans rats mimics the feeding behavior of obese Zucker rats. Int. J. Obes. 16:1992;295-302.
    • (1992) Int. J. Obes. , vol.16 , pp. 295-302
    • Beck, B.1    Stricker, K.A.2    Nicolas, J.P.3    Burlet, C.4
  • 2
    • 0025038674 scopus 로고
    • Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats
    • Brady L.S., Smith M.A., Gold P.W., Herkenham M. Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats. Neuroendocrinology. 52:1990;441-447.
    • (1990) Neuroendocrinology , vol.52 , pp. 441-447
    • Brady, L.S.1    Smith, M.A.2    Gold, P.W.3    Herkenham, M.4
  • 3
    • 0028922476 scopus 로고
    • Behavioral effects of neuropeptide Y receptor agonists in the elevated plus maze and fear-potentiated startle procedures
    • Broqua P., Wettstein J.G., Rocher M.N., Gauthier-Martin B., Junien J.L. Behavioral effects of neuropeptide Y receptor agonists in the elevated plus maze and fear-potentiated startle procedures. Behav. Pharmacol. 6:1995;215-222.
    • (1995) Behav. Pharmacol. , vol.6 , pp. 215-222
    • Broqua, P.1    Wettstein, J.G.2    Rocher, M.N.3    Gauthier-Martin, B.4    Junien, J.L.5
  • 6
    • 0026535166 scopus 로고
    • The role of the amygdala in fear and anxiety
    • Davis M. The role of the amygdala in fear and anxiety. Annu. Rev. Neurosci. 15:1992;353-375.
    • (1992) Annu. Rev. Neurosci. , vol.15 , pp. 353-375
    • Davis, M.1
  • 7
    • 0028335412 scopus 로고
    • Evidence that neuropeptide Y is a physiological signal for normal food intake
    • Dube M.G., Xu B., Crowley W.R., Kalra P.S., Kalra S.P. Evidence that neuropeptide Y is a physiological signal for normal food intake. Brain Res. 646:1994;341-344.
    • (1994) Brain Res. , vol.646 , pp. 341-344
    • Dube, M.G.1    Xu, B.2    Crowley, W.R.3    Kalra, P.S.4    Kalra, S.P.5
  • 8
    • 0001768913 scopus 로고    scopus 로고
    • Neuropeptide Y receptor types in the mammalian brain: Species differences and status in the human central nervous system
    • L. Grundemar, & S.R. Bloom. San Diego: Academic Press
    • Dumont Y., Jacques D., St-Pierre J.-A., Quirion R. Neuropeptide Y receptor types in the mammalian brain: species differences and status in the human central nervous system. Grundemar L., Bloom S.R. Neuropeptide Y and Drug Development. 1997;57-86 Academic Press, San Diego.
    • (1997) Neuropeptide Y and Drug Development , pp. 57-86
    • Dumont, Y.1    Jacques, D.2    St-Pierre, J.-A.3    Quirion, R.4
  • 9
    • 0029946644 scopus 로고    scopus 로고
    • Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
    • Erickson J.C., Clegg K.E., Palmiter R.D. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature. 381:1996;415-418.
    • (1996) Nature , vol.381 , pp. 415-418
    • Erickson, J.C.1    Clegg, K.E.2    Palmiter, R.D.3
  • 11
    • 0023621228 scopus 로고
    • Modulation of memory processing by neuropeptide Y
    • Flood J.F., Hernandez E.N., Morley J.E. Modulation of memory processing by neuropeptide Y. Brain Res. 421:1987;280-290.
    • (1987) Brain Res. , vol.421 , pp. 280-290
    • Flood, J.F.1    Hernandez, E.N.2    Morley, J.E.3
  • 12
    • 0031957139 scopus 로고    scopus 로고
    • Multiple receptors for the pancreatic polypeptide (PP-fold) family: Physiological implications
    • Gehlert D.R. Multiple receptors for the pancreatic polypeptide (PP-fold) family: physiological implications. P.S.E.B.M. 218:1998;7-22.
    • (1998) P.S.E.B.M. , vol.218 , pp. 7-22
    • Gehlert, D.R.1
  • 13
    • 0017709125 scopus 로고
    • Paraventricular area: Critical focus of a longitudinal neurocircuitry mediating food intake
    • Gold R.M., Jones A.P., Sawchenko P.E. Paraventricular area: critical focus of a longitudinal neurocircuitry mediating food intake. Physiol. Behav. 18:1977;1111-1119.
    • (1977) Physiol. Behav. , vol.18 , pp. 1111-1119
    • Gold, R.M.1    Jones, A.P.2    Sawchenko, P.E.3
  • 14
    • 0025773411 scopus 로고
    • The antinociceptive effects of spinally administered neuropeptide Y the rat: Systematic studies on structure-activity relationship
    • Hau X.-Y., Boublik J.H., Spicer M.A., Rivier J.E., Brown M.R., Yaksh T.L. The antinociceptive effects of spinally administered neuropeptide Y the rat: systematic studies on structure-activity relationship. J. Pharmacol. Exp. Ther. 258:1991;243-248.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 243-248
    • Hau, X.-Y.1    Boublik, J.H.2    Spicer, M.A.3    Rivier, J.E.4    Brown, M.R.5    Yaksh, T.L.6
  • 15
    • 0024310089 scopus 로고
    • Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models
    • Heilig M., Soderpalm B., Engel J.A., Widerlov E. Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models. Psychopharmacology. 98:1989;524-529.
    • (1989) Psychopharmacology , vol.98 , pp. 524-529
    • Heilig, M.1    Soderpalm, B.2    Engel, J.A.3    Widerlov, E.4
  • 16
    • 0033083323 scopus 로고    scopus 로고
    • Neuropeptide Y feeding receptors: Are multiple subtypes involved
    • Inui A. Neuropeptide Y feeding receptors: are multiple subtypes involved. Trends Pharmaceut. Sci. 20:1999;43-46.
    • (1999) Trends Pharmaceut. Sci. , vol.20 , pp. 43-46
    • Inui, A.1
  • 18
    • 0025721025 scopus 로고
    • Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food
    • Kalra S.P., Dube M.G., Sahu A., Phelps C.P., Karlra P.S. Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food. Proc. Natl. Acad. Sci. 88:1991;10931-10935.
    • (1991) Proc. Natl. Acad. Sci. , vol.88 , pp. 10931-10935
    • Kalra, S.P.1    Dube, M.G.2    Sahu, A.3    Phelps, C.P.4    Karlra, P.S.5
  • 19
    • 0345055310 scopus 로고    scopus 로고
    • Anxiolytic-like effect of neuropeptide (NPY) and NPY 13-36 microinjected into vacinity of locus coeruleus in rats
    • Kask A., Rago L., Harro J. Anxiolytic-like effect of neuropeptide (NPY) and NPY 13-36 microinjected into vacinity of locus coeruleus in rats. Brain Res. 788:1998;345-348.
    • (1998) Brain Res. , vol.788 , pp. 345-348
    • Kask, A.1    Rago, L.2    Harro, J.3
  • 20
    • 84991428449 scopus 로고
    • Kelly D.D
    • Stress-induced analgesia. Kelly D.D. Ann. N.Y. Acad. Sci. 467:1986.
    • (1986) Ann. N.Y. Acad. Sci. , vol.467
  • 21
    • 0024162617 scopus 로고
    • Hypothalamic paraventricular nucleus: Interaction between alpha 2-noradrenergic system and circulating hormones and nutrients in relation to energy balance
    • Leibowitz S.F. Hypothalamic paraventricular nucleus: Interaction between alpha 2-noradrenergic system and circulating hormones and nutrients in relation to energy balance. Neurosci., Biobehav. Rev. 12:1988;101-109.
    • (1988) Neurosci., Biobehav. Rev. , vol.12 , pp. 101-109
    • Leibowitz, S.F.1
  • 22
    • 0021732102 scopus 로고
    • Neuropeptide Y: A potent inducer of consummatory behavior in rats
    • Levine A.S., Morley J.E. Neuropeptide Y: A potent inducer of consummatory behavior in rats. Peptides. 5:1984;1025-1029.
    • (1984) Peptides , vol.5 , pp. 1025-1029
    • Levine, A.S.1    Morley, J.E.2
  • 23
    • 0032908877 scopus 로고    scopus 로고
    • Neuropeptide Y receptor antagonsits
    • Ling A.L. Neuropeptide Y receptor antagonsits. Exp. Opin. Ther. Patents. 9:1999;375-384.
    • (1999) Exp. Opin. Ther. Patents , vol.9 , pp. 375-384
    • Ling, A.L.1
  • 25
    • 0030000156 scopus 로고    scopus 로고
    • Effect on nociception of intracerebroventricular administration of low doses of neuropeptide Y in mice
    • Mellado M.L., Givert-Rahola J., Lagares R., Chover A.J., Mico J.A. Effect on nociception of intracerebroventricular administration of low doses of neuropeptide Y in mice. Life Sci. 58:1996;2409-2414.
    • (1996) Life Sci. , vol.58 , pp. 2409-2414
    • Mellado, M.L.1    Givert-Rahola, J.2    Lagares, R.3    Chover, A.J.4    Mico, J.A.5
  • 26
    • 58149446368 scopus 로고
    • The relation between fear induced by novel stimulation and exploratory behavior
    • Montgomery K.C. The relation between fear induced by novel stimulation and exploratory behavior. J. Comp. Physiol. Psychol. 48:1958;254-260.
    • (1958) J. Comp. Physiol. Psychol. , vol.48 , pp. 254-260
    • Montgomery, K.C.1
  • 29
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • Pellow S., Chopin P., File S.E., Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods. 14:1985;149-167.
    • (1985) J. Neurosci. Methods , vol.14 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 31
    • 0033137356 scopus 로고    scopus 로고
    • The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice
    • Ralph R.J., Varty G.B., Kelly M.A., Wang Y., Caron M.G., Rubinstein M., Grandy D.K., Low M.J., Geyer M.A. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. J. Neurosci. 19:1999;4627-4633.
    • (1999) J. Neurosci. , vol.19 , pp. 4627-4633
    • Ralph, R.J.1    Varty, G.B.2    Kelly, M.A.3    Wang, Y.4    Caron, M.G.5    Rubinstein, M.6    Grandy, D.K.7    Low, M.J.8    Geyer, M.A.9
  • 32
    • 0028299741 scopus 로고
    • Thigmotaxis as an index of anxiety in mice: Influence of dopaminergic transmission
    • Simon P., Dupuis R., Constentin J. Thigmotaxis as an index of anxiety in mice: influence of dopaminergic transmission. Behav. Brain Res. 61:1994;59-64.
    • (1994) Behav. Brain Res. , vol.61 , pp. 59-64
    • Simon, P.1    Dupuis, R.2    Constentin, J.3
  • 33
    • 0022873040 scopus 로고
    • Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity
    • Stanley B.G., Kyrkouli S.E., Lampert S., Leibowitz S.F. Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity. Peptides. 7:1986;1189-1192.
    • (1986) Peptides , vol.7 , pp. 1189-1192
    • Stanley, B.G.1    Kyrkouli, S.E.2    Lampert, S.3    Leibowitz, S.F.4
  • 34
    • 0033615251 scopus 로고    scopus 로고
    • Behavioral and endocrine adaptation, and upregulation of NPY expression in rat amygdala following repeated restraint stress
    • Thorsell A., Carlsson K., Ekman R., Heilig M. Behavioral and endocrine adaptation, and upregulation of NPY expression in rat amygdala following repeated restraint stress. Neuroreport. 10:1999;3003-3007.
    • (1999) Neuroreport , vol.10 , pp. 3003-3007
    • Thorsell, A.1    Carlsson, K.2    Ekman, R.3    Heilig, M.4
  • 35
    • 0024158498 scopus 로고
    • Thigmotaxis as a test for anxiolytic activity in rats
    • Treit D., Fundytus M. Thigmotaxis as a test for anxiolytic activity in rats. Pharmacol. Biochem. Behav. 31:1988;958-962.
    • (1988) Pharmacol. Biochem. Behav. , vol.31 , pp. 958-962
    • Treit, D.1    Fundytus, M.2


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