메뉴 건너뛰기




Volumn 851, Issue 1-2, 1999, Pages 198-203

Resistance to diet-induced obesity is associated with increased proopiomelanocortin mRNA and decreased neuropeptide Y mRNA in the hypothalamus

Author keywords

Diet induced obesity; High fat diet; Hypothalamus; Neuropeptide Y; Proopiomelanocortin

Indexed keywords

GLUCOSE; INSULIN; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN;

EID: 0033401863     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02186-1     Document Type: Article
Times cited : (86)

References (24)
  • 1
    • 0030058547 scopus 로고    scopus 로고
    • Ventromedial hypothalamic lesions produced by gold thioglucose do not impair induction of NPY mRNA in the arcuate nucleus by fasting
    • Bergen H.T., Mobbs C.V. Ventromedial hypothalamic lesions produced by gold thioglucose do not impair induction of NPY mRNA in the arcuate nucleus by fasting. Brain Res. 707:1996;266-271.
    • (1996) Brain Res. , vol.707 , pp. 266-271
    • Bergen, H.T.1    Mobbs, C.V.2
  • 2
    • 0031756060 scopus 로고    scopus 로고
    • Differential effects of fat and sucrose on body composition in A/J and C57Bl/6 mice
    • Black B.L., Croom J., Eisen E.J., Petro A.E., Edwards C.L., Surwit R.S. Differential effects of fat and sucrose on body composition in A/J and C57Bl/6 mice. Metabolism. 47:1998;1354-1359.
    • (1998) Metabolism , vol.47 , pp. 1354-1359
    • Black, B.L.1    Croom, J.2    Eisen, E.J.3    Petro, A.E.4    Edwards, C.L.5    Surwit, R.S.6
  • 4
    • 0021248888 scopus 로고
    • Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
    • Clark J.T., Kalra P.S., Crowley W., Kalra S.P. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology. 115:1984;427-429.
    • (1984) Endocrinology , vol.115 , pp. 427-429
    • Clark, J.T.1    Kalra, P.S.2    Crowley, W.3    Kalra, S.P.4
  • 5
    • 0029804743 scopus 로고    scopus 로고
    • Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
    • Erickson J.C., Holopeter G., Palmiter R.D. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science. 274:1996;1704-1707.
    • (1996) Science , vol.274 , pp. 1704-1707
    • Erickson, J.C.1    Holopeter, G.2    Palmiter, R.D.3
  • 6
    • 0032548825 scopus 로고    scopus 로고
    • Obesity and the hypothalamus: Novel peptides for new pathways
    • Flier J.S., Maratos-Flier E. Obesity and the hypothalamus: novel peptides for new pathways. Cell. 92:1998;437-440.
    • (1998) Cell , vol.92 , pp. 437-440
    • Flier, J.S.1    Maratos-Flier, E.2
  • 9
    • 0030894709 scopus 로고    scopus 로고
    • Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome
    • Kesterson R., Huszar D., Lynch C., Simerly R., Cone R. Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome. Mol. Endocrinol. 11:1997;630-637.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 630-637
    • Kesterson, R.1    Huszar, D.2    Lynch, C.3    Simerly, R.4    Cone, R.5
  • 10
    • 0031838353 scopus 로고    scopus 로고
    • Severe early onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
    • Krude H., Biebermann H., Luck W., Horn R., Brabant G., Grüters A. Severe early onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nature Genet. 19:1998;155-157.
    • (1998) Nature Genet. , vol.19 , pp. 155-157
    • Krude, H.1    Biebermann, H.2    Luck, W.3    Horn, R.4    Brabant, G.5    Grüters, A.6
  • 11
    • 0030938684 scopus 로고    scopus 로고
    • Dysregulation of arcuate nucleus preproneuropeptide Y mRNA in diet-induced obese rats
    • Levin B.E., Dunnmeynell A.A. Dysregulation of arcuate nucleus preproneuropeptide Y mRNA in diet-induced obese rats. Am. J. Physiol. 272:1997;R1365-R1370.
    • (1997) Am. J. Physiol. , vol.272
    • Levin, B.E.1    Dunnmeynell, A.A.2
  • 12
    • 0029983180 scopus 로고    scopus 로고
    • Obese gene expression: Reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity
    • Mizuno T.M., Bergen H.T., Funabashi T., Kleopoulos S.P., Zhong Y., Bauman W.A., Mobbs C.V. Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity. Proc. Natl. Acad. Sci. (USA). 93:1996;3434-3438.
    • (1996) Proc. Natl. Acad. Sci. (USA) , vol.93 , pp. 3434-3438
    • Mizuno, T.M.1    Bergen, H.T.2    Funabashi, T.3    Kleopoulos, S.P.4    Zhong, Y.5    Bauman, W.A.6    Mobbs, C.V.7
  • 13
    • 0031888157 scopus 로고    scopus 로고
    • Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin
    • Mizuno T., Kleopoulos S., Bergen H., Roberts J., Priest C., Mobbs C. Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin. Diabetes. 47:1998;294-297.
    • (1998) Diabetes , vol.47 , pp. 294-297
    • Mizuno, T.1    Kleopoulos, S.2    Bergen, H.3    Roberts, J.4    Priest, C.5    Mobbs, C.6
  • 15
    • 0025072899 scopus 로고
    • Increased hypothalamic content of NPY mRNA in genetically obese Zucker rats and in its regulation by food deprivation
    • Sanacora G., Kershaw M., Finkelstein J.A., White J.D. Increased hypothalamic content of NPY mRNA in genetically obese Zucker rats and in its regulation by food deprivation. Endocrinology. 127:1990;730-737.
    • (1990) Endocrinology , vol.127 , pp. 730-737
    • Sanacora, G.1    Kershaw, M.2    Finkelstein, J.A.3    White, J.D.4
  • 16
    • 0030775971 scopus 로고    scopus 로고
    • Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus
    • Schwartz M., Seeley R., Woods S., Weigle D., Campfield L., Burn P., Baskin D. Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes. 46:1997;2119-2123.
    • (1997) Diabetes , vol.46 , pp. 2119-2123
    • Schwartz, M.1    Seeley, R.2    Woods, S.3    Weigle, D.4    Campfield, L.5    Burn, P.6    Baskin, D.7
  • 17
    • 0022873040 scopus 로고
    • Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity
    • Stanley B.G., Kyrkouli S.E., Lampert S., Leibowitz S.F. Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity. Peptides. 7:1986;1189-1192.
    • (1986) Peptides , vol.7 , pp. 1189-1192
    • Stanley, B.G.1    Kyrkouli, S.E.2    Lampert, S.3    Leibowitz, S.F.4
  • 20
    • 0030804112 scopus 로고    scopus 로고
    • Low plasma leptin in response to dietary fat in diabetes- And obesity-prone mice
    • Surwit R.S., Petro A.E., Parekh P., Collins S. Low plasma leptin in response to dietary fat in diabetes- and obesity-prone mice. Diabetes. 46:1997;1516-1520.
    • (1997) Diabetes , vol.46 , pp. 1516-1520
    • Surwit, R.S.1    Petro, A.E.2    Parekh, P.3    Collins, S.4
  • 21
    • 0026025628 scopus 로고
    • Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice
    • Surwit R.S., Seldin M.F., Kuhn C.M., Cochrane C., Feinglos M.N. Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice. Diabetes. 40:1991;82-87.
    • (1991) Diabetes , vol.40 , pp. 82-87
    • Surwit, R.S.1    Seldin, M.F.2    Kuhn, C.M.3    Cochrane, C.4    Feinglos, M.N.5
  • 22
    • 0030729210 scopus 로고    scopus 로고
    • Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
    • Thornton J., Cheung C., Clifton D., Steiner R. Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice. Endocrinology. 138:1997;5063-5066.
    • (1997) Endocrinology , vol.138 , pp. 5063-5066
    • Thornton, J.1    Cheung, C.2    Clifton, D.3    Steiner, R.4
  • 23
    • 0027362079 scopus 로고
    • Chronic intracerebroventricular neuropeptide Y administration to normal rats mimics hormonal and metabolic changes of obesity
    • Zarjevski N., Cusin I., Vettor R., Rohner-Jeanrenaud F., Jeanrenaud B. Chronic intracerebroventricular neuropeptide Y administration to normal rats mimics hormonal and metabolic changes of obesity. Endocrinology. 133:1993;1753-1758.
    • (1993) Endocrinology , vol.133 , pp. 1753-1758
    • Zarjevski, N.1    Cusin, I.2    Vettor, R.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 24
    • 0028263609 scopus 로고
    • Intracerebroventricular administration of neuropeptide Y to normal rats has divergent effects on glucose utilization by adipose tissue and skeletal muscle
    • Zarjevski N., Cusin I., Vettor R., Rohner-Jeanrenaud F., Jeanrenaud B. Intracerebroventricular administration of neuropeptide Y to normal rats has divergent effects on glucose utilization by adipose tissue and skeletal muscle. Diabetes. 43:1994;764-769.
    • (1994) Diabetes , vol.43 , pp. 764-769
    • Zarjevski, N.1    Cusin, I.2    Vettor, R.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.