-
1
-
-
0024485697
-
Promoting effect of bile acids on gastric carcinogenesis induced by MNNG in rats
-
Takebayashi,M. (1989) Promoting effect of bile acids on gastric carcinogenesis induced by MNNG in rats. Nippon Geka Gakkai Zasshi, 90, 49-58.
-
(1989)
Nippon Geka Gakkai Zasshi
, vol.90
, pp. 49-58
-
-
Takebayashi, M.1
-
2
-
-
0032958831
-
Administration of an unconjugated bile acid increases duodenal tumors in a murine model of familial adenomatous polyposis
-
Mahmoud,N.N., Dannenberg,A.J., Bilinski,R.T., Mestre,J.R., Chadburn,A., Churchill,M., Martucci,C. and Bertagnolli,M.M. (1999) Administration of an unconjugated bile acid increases duodenal tumors in a murine model of familial adenomatous polyposis. Carcinogenesis, 20, 299-303.
-
(1999)
Carcinogenesis
, vol.20
, pp. 299-303
-
-
Mahmoud, N.N.1
Dannenberg, A.J.2
Bilinski, R.T.3
Mestre, J.R.4
Chadburn, A.5
Churchill, M.6
Martucci, C.7
Bertagnolli, M.M.8
-
3
-
-
0033066625
-
Bile acids as components of the duodenogastric refluxate: Detection, relationship to bilirubin, mechanism of injury and clinical relevance
-
Stein,H.J., Kauer,W.K., Feussner,H. and Siewert,J.R. (1999) Bile acids as components of the duodenogastric refluxate: detection, relationship to bilirubin, mechanism of injury and clinical relevance. Hepatogastroenterology, 46, 66-73.
-
(1999)
Hepatogastroenterology
, vol.46
, pp. 66-73
-
-
Stein, H.J.1
Kauer, W.K.2
Feussner, H.3
Siewert, J.R.4
-
4
-
-
0035451350
-
The role of bile acids in carcinogenesis
-
Debruyne,P.R., Bruyneel,E.A., Li,X., Zimber,A., Gespach,C. and Mareel,M.M. (2001) The role of bile acids in carcinogenesis. Mutat. Res., 480-481, 359-369.
-
(2001)
Mutat. Res.
, vol.480-481
, pp. 359-369
-
-
Debruyne, P.R.1
Bruyneel, E.A.2
Li, X.3
Zimber, A.4
Gespach, C.5
Mareel, M.M.6
-
5
-
-
0016209908
-
Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats
-
Narisawa,T., Magadia,N.E., Weisburger,J.H. and Wynder,E.L. (1974) Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats. J. Natl Cancer Inst., 53, 1093-1097.
-
(1974)
J. Natl. Cancer Inst.
, vol.53
, pp. 1093-1097
-
-
Narisawa, T.1
Magadia, N.E.2
Weisburger, J.H.3
Wynder, E.L.4
-
6
-
-
0017714087
-
Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats
-
Reddy,B.S., Watanabe,K., Weisburger,J.H. and Wynder,E.L. (1977) Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats. Cancer Res., 37, 3238-3242.
-
(1977)
Cancer Res.
, vol.37
, pp. 3238-3242
-
-
Reddy, B.S.1
Watanabe, K.2
Weisburger, J.H.3
Wynder, E.L.4
-
7
-
-
0024419597
-
Shift from a mixed to a lactovegetarian diet: Influence on acidic lipids in fecal water-a potential risk factor for colon cancer
-
Allinger,U.G., Johansson,G.K., Gustafsson,J.-A. and Rafter,J.J. (1989) Shift from a mixed to a lactovegetarian diet: influence on acidic lipids in fecal water-a potential risk factor for colon cancer. Am. J. Clin. Nutr., 50, 992-996.
-
(1989)
Am. J. Clin. Nutr.
, vol.50
, pp. 992-996
-
-
Allinger, U.G.1
Johansson, G.K.2
Gustafsson, J.-A.3
Rafter, J.J.4
-
8
-
-
0029094616
-
Role of apoptosis in biology and pathology: Resistance to apoptosis in colon carcinogenesis
-
Payne,C.M., Bernstein,H., Bernstein,C. and Garewal,H. (1995) Role of apoptosis in biology and pathology: Resistance to apoptosis in colon carcinogenesis. Ultrastruct. Pathol., 19, 221-248.
-
(1995)
Ultrastruct. Pathol.
, vol.19
, pp. 221-248
-
-
Payne, C.M.1
Bernstein, H.2
Bernstein, C.3
Garewal, H.4
-
9
-
-
0030002903
-
Reduced bile acid-induced apoptosis in 'normal' colorectal mucosa: A potential biological marker for cancer risk
-
Garewal,H., Bernstein,H., Bernstein,C., Sampliner,R. and Payne,C. (1996) Reduced bile acid-induced apoptosis in 'normal' colorectal mucosa: A potential biological marker for cancer risk. Cancer Res., 56, 1480-1483.
-
(1996)
Cancer Res.
, vol.56
, pp. 1480-1483
-
-
Garewal, H.1
Bernstein, H.2
Bernstein, C.3
Sampliner, R.4
Payne, C.5
-
10
-
-
0033563140
-
A bile acid-induced apoptosis assay for colon cancer risk and associated quality control studies
-
Bernstein,C., Bernstein,H., Garewal,H., Dinning,P., Jabi,R., Sampliner,R.E., McCuskey,M.K., Panda,M., Roe,D.J., L'Heureux,L. and Payne,C. (1999) A bile acid-induced apoptosis assay for colon cancer risk and associated quality control studies. Cancer Res., 59, 2353-2357.
-
(1999)
Cancer Res.
, vol.59
, pp. 2353-2357
-
-
Bernstein, C.1
Bernstein, H.2
Garewal, H.3
Dinning, P.4
Jabi, R.5
Sampliner, R.E.6
McCuskey, M.K.7
Panda, M.8
Roe, D.J.9
L'Heureux, L.10
Payne, C.11
-
11
-
-
0036279724
-
Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients
-
Bernstein,H., Holubec,H., Warneke,J.A., Garewal,H., Earnest,D.L., Payne,C.M., Roe,D.J., Cui,H.C., Jacobson,E.L. and Bernstein,C. (2002) Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients. Annal. Surg. Oncol., 9, 505-517.
-
(2002)
Annal. Surg. Oncol.
, vol.9
, pp. 505-517
-
-
Bernstein, H.1
Holubec, H.2
Warneke, J.A.3
Garewal, H.4
Earnest, D.L.5
Payne, C.M.6
Roe, D.J.7
Cui, H.C.8
Jacobson, E.L.9
Bernstein, C.10
-
12
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed,J.C. (1999) Mechanisms of apoptosis avoidance in cancer. Curr. Opin. Oncol., 11, 68-75.
-
(1999)
Curr. Opin. Oncol.
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
13
-
-
0033301989
-
Reactive nitrogen species in colon carcinogenesis
-
Review
-
Payne,C.M., Bernstein,C., Bernstein,H., Gerner,E.W. and Garewal,H. (1999) Reactive nitrogen species in colon carcinogenesis. Review. Antiox. Redox Signaling, 1, 449-467.
-
(1999)
Antiox. Redox Signaling
, vol.1
, pp. 449-467
-
-
Payne, C.M.1
Bernstein, C.2
Bernstein, H.3
Gerner, E.W.4
Garewal, H.5
-
14
-
-
0035478953
-
Apoptosis regulators and their role in tumorigenesis
-
1551
-
Zornig,M., Hueber,A., Baum,W. and Evan,G. (2001) Apoptosis regulators and their role in tumorigenesis. Biochim. Biophys. Acta, 1551, F1-F37.
-
(2001)
Biochim. Biophys. Acta
-
-
Zornig, M.1
Hueber, A.2
Baum, W.3
Evan, G.4
-
15
-
-
0036467477
-
Apoptosis and tumourigenesis
-
Hickman,J.A. (2002) Apoptosis and tumourigenesis. Curr. Opin. Genet. Dev., 12, 67-72.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 67-72
-
-
Hickman, J.A.1
-
16
-
-
0036468550
-
Dysfunctional apoptosome activation in ovarian cancer: Implications for chemoresistance
-
Liu,J.R., Opipari,A.W., Tan,L., Jiang,Y., Zhang,Y., Tang,H. and Nunez,G. (2002) Dysfunctional apoptosome activation in ovarian cancer: implications for chemoresistance. Cancer Res., 62, 924-931.
-
(2002)
Cancer Res.
, vol.62
, pp. 924-931
-
-
Liu, J.R.1
Opipari, A.W.2
Tan, L.3
Jiang, Y.4
Zhang, Y.5
Tang, H.6
Nunez, G.7
-
17
-
-
0037169358
-
Apoptosis: A link between cancer and chemotherapy
-
Johnstone,R.W., Ruefli,A.A. and Lowe,S.W. (2002) Apoptosis: a link between cancer and chemotherapy. Cell, 108, 153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
18
-
-
0029808933
-
Suppression of apoptosis by Bcl-2 or Bcl-xL promotes susceptibility to mutagenesis
-
Cherbonnel-Lasserre,C., Gauny,S. and Kronenberg,A. (1996) Suppression of apoptosis by Bcl-2 or Bcl-xL promotes susceptibility to mutagenesis. Oncogene, 13, 1489-1497.
-
(1996)
Oncogene
, vol.13
, pp. 1489-1497
-
-
Cherbonnel-Lasserre, C.1
Gauny, S.2
Kronenberg, A.3
-
19
-
-
0031467933
-
Suppression of apoptosis by overexpression of Bcl-2 or Bcl-xL promotes survival and mutagenesis after oxidative damage
-
Cherbonnel-Lasserre,C. and Dosanjh,M.K. (1997) Suppression of apoptosis by overexpression of Bcl-2 or Bcl-xL promotes survival and mutagenesis after oxidative damage. Biochimie, 79, 613-617.
-
(1997)
Biochimie
, vol.79
, pp. 613-617
-
-
Cherbonnel-Lasserre, C.1
Dosanjh, M.K.2
-
20
-
-
0035873741
-
A novel role for the Bcl-2 protein family: Specific suppression of the Rad51 recombination pathway
-
Saintigny,Y., Dumay,A., Lambert,S. and Lopez,B.S. (2001) A novel role for the Bcl-2 protein family: specific suppression of the Rad51 recombination pathway. EMBO J., 20, 2596-2607.
-
(2001)
EMBO J.
, vol.20
, pp. 2596-2607
-
-
Saintigny, Y.1
Dumay, A.2
Lambert, S.3
Lopez, B.S.4
-
21
-
-
0033592960
-
The onset and extent of genomic instability in sporadic colorectal tumor progression
-
Stoler,D.L., Chen,N., Basik,M., Kahlenberg,M.S., Rodriguez-Bigas,M.A., Petrelli,N.J. and Anderson,G.R. (1999) The onset and extent of genomic instability in sporadic colorectal tumor progression. Proc. Natl Acad. Sci. USA, 96, 15121-15126.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 15121-15126
-
-
Stoler, D.L.1
Chen, N.2
Basik, M.3
Kahlenberg, M.S.4
Rodriguez-Bigas, M.A.5
Petrelli, N.J.6
Anderson, G.R.7
-
22
-
-
0028941441
-
Inhibition of apoptosis during development of colorectal cancer
-
Bedi,A., Pasricha,P.J., Akhtar,A.J., Barber,J.P., Bedi,G.C., Giardiello,F.M., Zehnbauer,B.A., Hamilton,S.R. and Jones,R.J. (1995) Inhibition of apoptosis during development of colorectal cancer. Cancer Res., 55, 1811-1816.
-
(1995)
Cancer Res.
, vol.55
, pp. 1811-1816
-
-
Bedi, A.1
Pasricha, P.J.2
Akhtar, A.J.3
Barber, J.P.4
Bedi, G.C.5
Giardiello, F.M.6
Zehnbauer, B.A.7
Hamilton, S.R.8
Jones, R.J.9
-
23
-
-
0030806077
-
Significance of apoptosis in the process of tumorigenesis in colorectal mucosa and adenomas in FAP patients
-
Weiss,H., Jacobasch,K.H., Haensch,W., Streller,B. and Hieke,B. (1997) Significance of apoptosis in the process of tumorigenesis in colorectal mucosa and adenomas in FAP patients. Anal. Cell. Pathol., 14, 61-73.
-
(1997)
Anal. Cell Pathol.
, vol.14
, pp. 61-73
-
-
Weiss, H.1
Jacobasch, K.H.2
Haensch, W.3
Streller, B.4
Hieke, B.5
-
24
-
-
0034881170
-
Fas ligand upregulation is an early event in colonic carcinogenesis
-
Bennett,M.W., O'Connell,J., Houston,A., Kelly,J., O'Sullivan,G.C., Collins,J.K. and Shanahan,F. (2001) Fas ligand upregulation is an early event in colonic carcinogenesis. J. Clin. Pathol., 54, 598-604.
-
(2001)
J. Clin. Pathol.
, vol.54
, pp. 598-604
-
-
Bennett, M.W.1
O'Connell, J.2
Houston, A.3
Kelly, J.4
O'Sullivan, G.C.5
Collins, J.K.6
Shanahan, F.7
-
25
-
-
0028333937
-
Programmed cell death of the normal human neutrophil: An in vitro model of senescence
-
Payne,C.M., Glasser,L., Tischler,M.E., Wyckoff,D., Cromey,D., Fiederlein,R. and Bohnert,O. (1994) Programmed cell death of the normal human neutrophil: an in vitro model of senescence. Microsc. Res. Tech., 28, 327-344.
-
(1994)
Microsc. Res. Tech.
, vol.28
, pp. 327-344
-
-
Payne, C.M.1
Glasser, L.2
Tischler, M.E.3
Wyckoff, D.4
Cromey, D.5
Fiederlein, R.6
Bohnert, O.7
-
26
-
-
0031874147
-
The stress-response proteins poly (ADP-ribose) polymerase and NF-κB protect against bile salt-induced apoptosis
-
Payne,C.M., Crowley,C., Washo-Stultz,D., Briehl,M., Bernstein,H., Bernstein,C., Beard,S., Holubec,H. and Warneke,J. (1998) The stress-response proteins poly (ADP-ribose) polymerase and NF-κB protect against bile salt-induced apoptosis. Cell Death Different., 5, 623-636.
-
(1998)
Cell Death Different.
, vol.5
, pp. 623-636
-
-
Payne, C.M.1
Crowley, C.2
Washo-Stultz, D.3
Briehl, M.4
Bernstein, H.5
Bernstein, C.6
Beard, S.7
Holubec, H.8
Warneke, J.9
-
27
-
-
0034108869
-
+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate
-
+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate. Cell Death Different., 7, 314-326.
-
(2000)
Cell Death Different.
, vol.7
, pp. 314-326
-
-
Crowley, C.L.1
Payne, C.M.2
Bernstein, H.3
Bernstein, C.4
Roe, D.5
-
28
-
-
0037187452
-
Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis
-
Washo-Stultz,D., Crowley-Weber,C.L., Dvorakova,K., Bernstein,C., Bernstein,H., Kunke,K., Waltmire,C.N., Garewal,H. and Payne,C.M. (2002) Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis. Cancer Lett., 177, 129-144.
-
(2002)
Cancer Lett.
, vol.177
, pp. 129-144
-
-
Washo-Stultz, D.1
Crowley-Weber, C.L.2
Dvorakova, K.3
Bernstein, C.4
Bernstein, H.5
Kunke, K.6
Waltmire, C.N.7
Garewal, H.8
Payne, C.M.9
-
29
-
-
0029966796
-
Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis
-
Macho,A., Decaudin,D., Castedo,M., Hirsch,T., Susin,S.A., Zamzami,N. and Kroemer,G. (1996) Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry, 25, 333-340.
-
(1996)
Cytometry
, vol.25
, pp. 333-340
-
-
Macho, A.1
Decaudin, D.2
Castedo, M.3
Hirsch, T.4
Susin, S.A.5
Zamzami, N.6
Kroemer, G.7
-
30
-
-
0035383778
-
Induction of mitochondrial changes in myeloma cells by imexon
-
Dvorakova,K., Waltmire,C.N., Payne,C.M., Tome,M.E., Briehl,M.M. and Dorr,R.T. (2001) Induction of mitochondrial changes in myeloma cells by imexon. Blood, 97, 3544-3551.
-
(2001)
Blood
, vol.97
, pp. 3544-3551
-
-
Dvorakova, K.1
Waltmire, C.N.2
Payne, C.M.3
Tome, M.E.4
Briehl, M.M.5
Dorr, R.T.6
-
31
-
-
0016711037
-
High resolution two-dimensional electrophoresis of proteins
-
O'Farrell,P.H. (1975) High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem., 250, 4007-4021.
-
(1975)
J. Biol. Chem.
, vol.250
, pp. 4007-4021
-
-
O'Farrell, P.H.1
-
32
-
-
0030898043
-
Identification of mouse liver proteins on two-dimensional electrophoresis gels by matrix-assisted laser desorption/ionization mass spectrometry of in situ enzymatic digests
-
O'Connell,K.L. and Stults,J.T. (1997) Identification of mouse liver proteins on two-dimensional electrophoresis gels by matrix-assisted laser desorption/ionization mass spectrometry of in situ enzymatic digests. Electrophoresis, 18, 349-359.
-
(1997)
Electrophoresis
, vol.18
, pp. 349-359
-
-
O'Connell, K.L.1
Stults, J.T.2
-
33
-
-
0025726646
-
Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-κB
-
Ruben,S.M., Dillon,P.J., Schreck,R., Henkel,T., Chen,C.-H., Maher,M., Baeuerle,P.A. and Rosen,C.A. (1991) Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-κB. Science, 251, 1490-1493.
-
(1991)
Science
, vol.251
, pp. 1490-1493
-
-
Ruben, S.M.1
Dillon, P.J.2
Schreck, R.3
Henkel, T.4
Chen, C.-H.5
Maher, M.6
Baeuerle, P.A.7
Rosen, C.A.8
-
34
-
-
0033500355
-
Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: Relevance to colon carcinogenesis
-
Washo-Stultz,D., Hoglen,N., Bernstein,H., Bernstein,C. and Payne,C.M. (1999) Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: relevance to colon carcinogenesis. Nutr. Cancer, 35, 180-188.
-
(1999)
Nutr. Cancer
, vol.35
, pp. 180-188
-
-
Washo-Stultz, D.1
Hoglen, N.2
Bernstein, H.3
Bernstein, C.4
Payne, C.M.5
-
35
-
-
0031428472
-
Genotoxic activity in human faecal water and the role of bile acids: A study using the alkaline comet assay
-
Venturi,M., Hambly,R.J., Glinghammer,B., Rafter,J.J. and Rowland,I.R. (1997) Genotoxic activity in human faecal water and the role of bile acids: a study using the alkaline comet assay. Carcinogenesis, 18, 2353-2359.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2353-2359
-
-
Venturi, M.1
Hambly, R.J.2
Glinghammer, B.3
Rafter, J.J.4
Rowland, I.R.5
-
36
-
-
0032951918
-
Free radical-induced megamitochondria formation and apoptosis
-
Karbowski,M., Kurono,C., Wozniak,M., Ostrowski,M., Teranishi,M., Nishizawa,Y., Usukura,J., Soji,T. and Wakabayashi,T. (1999) Free radical-induced megamitochondria formation and apoptosis. Free Rad. Biol. Med., 26, 396-409.
-
(1999)
Free Rad. Biol. Med.
, vol.26
, pp. 396-409
-
-
Karbowski, M.1
Kurono, C.2
Wozniak, M.3
Ostrowski, M.4
Teranishi, M.5
Nishizawa, Y.6
Usukura, J.7
Soji, T.8
Wakabayashi, T.9
-
37
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky,D.J. and Emr,S.D. (2000) Autophagy as a regulated pathway of cellular degradation. Science, 290, 1717-1721.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
38
-
-
0025772343
-
Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
-
Henderson,S., Rowe,M., Gregory,C., Croom-Carter,D., Wang,F., Longnecker,R., Kieff,E. and Rickinson,A. (1991) Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell, 65, 1107-1115.
-
(1991)
Cell
, vol.65
, pp. 1107-1115
-
-
Henderson, S.1
Rowe, M.2
Gregory, C.3
Croom-Carter, D.4
Wang, F.5
Longnecker, R.6
Kieff, E.7
Rickinson, A.8
-
39
-
-
0030765016
-
Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances and cell death in renal epithelial cells
-
Liu,H., Bowes III,R.C., van de Water,B., Sillence,C., Nagelkerke,J.F. and Stevens,J.L. (1997) Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances and cell death in renal epithelial cells. J. Biol. Chem., 272, 21751-21759.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21751-21759
-
-
Liu, H.1
Bowes R.C. III2
van de Water, B.3
Sillence, C.4
Nagelkerke, J.F.5
Stevens, J.L.6
-
40
-
-
0031682263
-
Expression of cell death regulatory genes and limited apoptosis induction in avian blastodermal cells
-
Muscarella,D.E., Rachlinski,M.K. and Bloom,S.E. (1998) Expression of cell death regulatory genes and limited apoptosis induction in avian blastodermal cells. Mol. Reprod. Dev., 51, 130-142.
-
(1998)
Mol. Reprod. Dev.
, vol.51
, pp. 130-142
-
-
Muscarella, D.E.1
Rachlinski, M.K.2
Bloom, S.E.3
-
41
-
-
0033618443
-
Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate
-
Bernstein,H., Payne,C.M., Bernstein,C., Schneider,J., Beard,S.E. and Crowley,C.L. (1999) Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate. Toxicol. Lett., 108, 37-46.
-
(1999)
Toxicol. Lett.
, vol.108
, pp. 37-46
-
-
Bernstein, H.1
Payne, C.M.2
Bernstein, C.3
Schneider, J.4
Beard, S.E.5
Crowley, C.L.6
-
42
-
-
0035914341
-
The bile acid glycochenodeoxycholate induces TRAIL-receptor 2/DR5 expression and apoptosis
-
Higuchi,H., Bronk,S.F., Yakikawa,Y., Werneburg,N., Takimoto,R., El-Deiry,W. and Gores,G.J. (2001) The bile acid glycochenodeoxycholate induces TRAIL-receptor 2/DR5 expression and apoptosis. J. Biol. Chem., 276, 38610-38618.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38610-38618
-
-
Higuchi, H.1
Bronk, S.F.2
Yakikawa, Y.3
Werneburg, N.4
Takimoto, R.5
El-Deiry, W.6
Gores, G.J.7
-
43
-
-
0035167269
-
Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: Inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis
-
Qiao,L., Studer,E., Leach,K., McKinstry,R., Gupta,S., Decker,R., Kukreja,R., Valerie,K., Nagarkatti,P., El Deiry,W., Molkentin,J., Schmidt-Ullrich,R., Fisher,P.B., Grant,S., Hylemon,P.B. and Dent,P. (2001) Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis. Mol. Biol. Cell, 12, 2629-2645.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2629-2645
-
-
Qiao, L.1
Studer, E.2
Leach, K.3
McKinstry, R.4
Gupta, S.5
Decker, R.6
Kukreja, R.7
Valerie, K.8
Nagarkatti, P.9
El Deiry, W.10
Molkentin, J.11
Schmidt-Ullrich, R.12
Fisher, P.B.13
Grant, S.14
Hylemon, P.B.15
Dent, P.16
-
44
-
-
0036241214
-
Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in s c-jun N-terminal kinase-dependent manner
-
Graf,D., Kurz,A.K., Fischer,R., Reinehr,R. and Haussinger,D. (2002) Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in s c-jun N-terminal kinase-dependent manner. Gastroenterology, 122, 1411-1427.
-
(2002)
Gastroenterology
, vol.122
, pp. 1411-1427
-
-
Graf, D.1
Kurz, A.K.2
Fischer, R.3
Reinehr, R.4
Haussinger, D.5
-
45
-
-
0036151709
-
Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
-
Rao,Y.P., Studer,E.J., Stravitz,R.T., Gupta,S., Qiao,L., Dent,P. and Hylemon,P.B. (2002) Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology, 35, 307-314.
-
(2002)
Hepatology
, vol.35
, pp. 307-314
-
-
Rao, Y.P.1
Studer, E.J.2
Stravitz, R.T.3
Gupta, S.4
Qiao, L.5
Dent, P.6
Hylemon, P.B.7
-
46
-
-
0036208350
-
Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line
-
Yoon,J.-H., Higuchi,H., Werneburg,N.W., Kaufmann,S.H. and Gores,G.J. (2002) Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. Gastroenterology, 122, 985-993.
-
(2002)
Gastroenterology
, vol.122
, pp. 985-993
-
-
Yoon, J.-H.1
Higuchi, H.2
Werneburg, N.W.3
Kaufmann, S.H.4
Gores, G.J.5
-
47
-
-
0028902762
-
Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids
-
Pongracz,J., Clark,P., Neoptolemos,J.P. and Lord,J.M. (1995) Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids. Int. J. Cancer, 61, 35-39.
-
(1995)
Int. J. Cancer
, vol.61
, pp. 35-39
-
-
Pongracz, J.1
Clark, P.2
Neoptolemos, J.P.3
Lord, J.M.4
-
48
-
-
0030906632
-
Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C
-
Jones,B.A., Rao,Y.P., Stravitz,R.T. and Gores,G.J. (1997) Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C. Am. J. Physiol., 272, G1109-G1115.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Jones, B.A.1
Rao, Y.P.2
Stravitz, R.T.3
Gores, G.J.4
-
49
-
-
0031459956
-
Activation of protein kinase C alpha and delta by bile acids: Correlation with bile acid structure and diacylglycerol formation
-
Rao,Y.P., Stravitz,R.T., Vlahcevic,Z.R., Gurley,E.C., Sando,J.J. and Hylemon,P.B. (1997) Activation of protein kinase C alpha and delta by bile acids: correlation with bile acid structure and diacylglycerol formation. J. Lipid Res., 38, 2446-2454.
-
(1997)
J. Lipid Res.
, vol.38
, pp. 2446-2454
-
-
Rao, Y.P.1
Stravitz, R.T.2
Vlahcevic, Z.R.3
Gurley, E.C.4
Sando, J.J.5
Hylemon, P.B.6
-
50
-
-
0032985843
-
Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes
-
Beuers,U., Probst,I., Soroka,C., Boyer,J.L., Kullak-Ublick,G.A. and Paumgartner,G. (1999) Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes. Hepatology, 29, 477-482.
-
(1999)
Hepatology
, vol.29
, pp. 477-482
-
-
Beuers, U.1
Probst, I.2
Soroka, C.3
Boyer, J.L.4
Kullak-Ublick, G.A.5
Paumgartner, G.6
-
51
-
-
0034130810
-
Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity
-
Gonzalez,B., Fisher,C. and Rosser,B.G. (2000) Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol. Cell. Biochem., 207, 19-27.
-
(2000)
Mol. Cell Biochem.
, vol.207
, pp. 19-27
-
-
Gonzalez, B.1
Fisher, C.2
Rosser, B.G.3
-
52
-
-
0034733547
-
The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade
-
Rust,C., Karnitz,L.M., Paya,C.V., Moscat,J., Simari,R.D. and Gores,G.J. (2000) The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. J. Biol. Chem., 275, 20210-20216.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20210-20216
-
-
Rust, C.1
Karnitz, L.M.2
Paya, C.V.3
Moscat, J.4
Simari, R.D.5
Gores, G.J.6
-
53
-
-
0035135599
-
Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis
-
Qiao,D., Stratagouleas,E.D. and Martinez,J.D. (2001) Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis. Carcinogenesis, 22, 35-41.
-
(2001)
Carcinogenesis
, vol.22
, pp. 35-41
-
-
Qiao, D.1
Stratagouleas, E.D.2
Martinez, J.D.3
-
54
-
-
0035014692
-
The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits fas apoptosis upstream of bid in rodent hepatocytes
-
Takikawa,Y., Miyoshi,H., Rust,C., Roberts,P., Siegel,R., Mandal,P.K., Millikan,R.E. and Gores,G.J. (2001) The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits fas apoptosis upstream of bid in rodent hepatocytes. Gastroenterology, 120, 1810-1817.
-
(2001)
Gastroenterology
, vol.120
, pp. 1810-1817
-
-
Takikawa, Y.1
Miyoshi, H.2
Rust, C.3
Roberts, P.4
Siegel, R.5
Mandal, P.K.6
Millikan, R.E.7
Gores, G.J.8
-
55
-
-
0035123848
-
Phosphoinositide 3-kinase, but not mitogen-activated protein kinase, pathway is involved in hepatocyte growth factor-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes
-
Webster,C.R. and Anwer,M.S. (2001) Phosphoinositide 3-kinase, but not mitogen-activated protein kinase, pathway is involved in hepatocyte growth factor-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes. Hepatology, 33, 608-615.
-
(2001)
Hepatology
, vol.33
, pp. 608-615
-
-
Webster, C.R.1
Anwer, M.S.2
-
56
-
-
0031436253
-
Increased activity of group II phospholipase A2 in plasma in rat sodium deoxycholate-induced acute pancreatitis
-
Furue,S., Hori,Y., Kuwabara,K., Ikeuchi,J., Onoyama,H., Yamamoto,M. and Tanaka,K. (1997) Increased activity of group II phospholipase A2 in plasma in rat sodium deoxycholate-induced acute pancreatitis. Gut, 41, 826-831.
-
(1997)
Gut
, vol.41
, pp. 826-831
-
-
Furue, S.1
Hori, Y.2
Kuwabara, K.3
Ikeuchi, J.4
Onoyama, H.5
Yamamoto, M.6
Tanaka, K.7
-
57
-
-
0021687474
-
Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products
-
DeRubertis,F.R., Craven,P.A. and Saito,R. (1984) Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products. J. Clin. Invest., 74, 1614-1624.
-
(1984)
J. Clin. Invest.
, vol.74
, pp. 1614-1624
-
-
De Rubertis, F.R.1
Craven, P.A.2
Saito, R.3
-
58
-
-
0023258585
-
Fatty acid composition of phospholipids in bile in man: Promoting effect of deoxycholate on arachidonate
-
Van Berge Henegouwen,G.P., van der Werf,S.D. and Ruben,A.T. (1987) Fatty acid composition of phospholipids in bile in man: promoting effect of deoxycholate on arachidonate. Clin. Chim. Acta, 165, 27-37.
-
(1987)
Clin. Chim. Acta
, vol.165
, pp. 27-37
-
-
Van Berge Henegouwen, G.P.1
van der Werf, S.D.2
Ruben, A.T.3
-
60
-
-
0028181166
-
Stimulation of prostaglandin E2 release from cultured rabbit gastric cells by sodium deoxycholate
-
Hata,Y., Ota,S., Terano,A., Kohmoto,O., Yoshiura,K., Okano,K., Ivey,K.J. and Sugimoto,T. (1994) Stimulation of prostaglandin E2 release from cultured rabbit gastric cells by sodium deoxycholate. Prostaglandins, 47, 423-436.
-
(1994)
Prostaglandins
, vol.47
, pp. 423-436
-
-
Hata, Y.1
Ota, S.2
Terano, A.3
Kohmoto, O.4
Yoshiura, K.5
Okano, K.6
Ivey, K.J.7
Sugimoto, T.8
-
61
-
-
0023221033
-
Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity
-
Craven,P.A., Pfanstiel,J., Saito,R. and DeRubertis,F.R. (1987) Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity. Gastroenterology, 92, 1998-2008.
-
(1987)
Gastroenterology
, vol.92
, pp. 1998-2008
-
-
Craven, P.A.1
Pfanstiel, J.2
Saito, R.3
DeRubertis, F.R.4
-
62
-
-
0031027992
-
Inhibition of bile salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E
-
Patel,T. and Gores,G.J. (1997) Inhibition of bile salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E. Tox. Appl. Pharmacol., 142, 116-122.
-
(1997)
Tox. Appl. Pharmacol.
, vol.142
, pp. 116-122
-
-
Patel, T.1
Gores, G.J.2
-
63
-
-
0032789526
-
Bile salt activation of stress response promoters in Escherichia coli
-
Bernstein,C., Bernstein,H., Payne,C.M., Beard,S.E. and Schneider,J. (1999) Bile salt activation of stress response promoters in Escherichia coli. Curr. Microbiol., 39, 68-72.
-
(1999)
Curr. Microbiol.
, vol.39
, pp. 68-72
-
-
Bernstein, C.1
Bernstein, H.2
Payne, C.M.3
Beard, S.E.4
Schneider, J.5
-
64
-
-
0035069055
-
Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids
-
Sokol,R.J., Straka,M.S., Dahl,R., Devereaux,M.W., Yerushalmi,B., Gumpricht,E., Elkins,N. and Everson,G. (2001) Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediat. Res., 49, 519-531.
-
(2001)
Pediat. Res.
, vol.49
, pp. 519-531
-
-
Sokol, R.J.1
Straka, M.S.2
Dahl, R.3
Devereaux, M.W.4
Yerushalmi, B.5
Gumpricht, E.6
Elkins, N.7
Everson, G.8
-
65
-
-
0035129976
-
Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
-
Yerushalmi,B., Dahl,R., Devereaux,M.W., Gumpricht,E. and Sokol,R.J. (2001) Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology, 33, 616-626.
-
(2001)
Hepatology
, vol.33
, pp. 616-626
-
-
Yerushalmi, B.1
Dahl, R.2
Devereaux, M.W.3
Gumpricht, E.4
Sokol, R.J.5
-
66
-
-
0022657003
-
Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids
-
Hayes,J.D. and Mantle,T.J. (1986) Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids. Biochem. J., 233, 407-415.
-
(1986)
Biochem. J.
, vol.233
, pp. 407-415
-
-
Hayes, J.D.1
Mantle, T.J.2
-
67
-
-
0027661435
-
Bile acid inhibition of xenobiotic-metabolizing enzymes is a factor in the mechanism of colon carcinogenesis: Tests of aspects of the concept with glucuronosyltransferase
-
Schneider,H., Fiander,H., Latta,R.K. and Ross,N.W. (1993) Bile acid inhibition of xenobiotic-metabolizing enzymes is a factor in the mechanism of colon carcinogenesis: tests of aspects of the concept with glucuronosyltransferase. Eur. J. Cancer Prevent., 2, 393-400.
-
(1993)
Eur. J. Cancer Prevent.
, vol.2
, pp. 393-400
-
-
Schneider, H.1
Fiander, H.2
Latta, R.K.3
Ross, N.W.4
-
68
-
-
0026327144
-
Bile salt/acid induction of DNA damage in bacterial and mammalian cells: Implications for colon cancer
-
Kandell,R.L. and Bernstein,C. (1991) Bile salt/acid induction of DNA damage in bacterial and mammalian cells: Implications for colon cancer. Nutr. Cancer, 16, 227-238.
-
(1991)
Nutr. Cancer
, vol.16
, pp. 227-238
-
-
Kandell, R.L.1
Bernstein, C.2
-
69
-
-
0026439241
-
Bile salt/acid induction of DNA damage in bacterial cells: Effect of taurine conjugation
-
Zheng,Z.-Y. and Bernstein,C. (1992) Bile salt/acid induction of DNA damage in bacterial cells: effect of taurine conjugation. Nutr. Cancer, 18, 157-164.
-
(1992)
Nutr. Cancer
, vol.18
, pp. 157-164
-
-
Zheng, Z.-Y.1
Bernstein, C.2
-
70
-
-
0012647014
-
-
Aruoma, O.I. and Halliwell, B. (eds)
-
Booth,L.A. and Bilton,R.F. (1998) In Aruoma, O.I. and Halliwell, B. (eds), Genotoxic Potential of the Secondary Bile Acids: a Role for Reactive Oxygen Species, pp. 161-177.
-
(1998)
Genotoxic Potential of the Secondary Bile Acids: A Role for Reactive Oxygen Species
, pp. 161-177
-
-
Booth, L.A.1
Bilton, R.F.2
-
71
-
-
0020566865
-
Early histopathologic events to evolution of colon cancer in C57BL/6 and CF1 mice treated with, 1,2-dimethylhydrazine
-
Wargovich,M.J., Medline,A. and Bruce,W.R. (1983) Early histopathologic events to evolution of colon cancer in C57BL/6 and CF1 mice treated with, 1,2-dimethylhydrazine. J. Natl Cancer Inst., 71, 125-131.
-
(1983)
J. Natl. Cancer Inst.
, vol.71
, pp. 125-131
-
-
Wargovich, M.J.1
Medline, A.2
Bruce, W.R.3
-
72
-
-
0036952927
-
Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA
-
Allgayer,H., Kolb,M., Stuber,V. and Kruis,W. (2002) Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA. Cancer Det. Prevent., 26, 85-89.
-
(2002)
Cancer Det. Prevent.
, vol.26
, pp. 85-89
-
-
Allgayer, H.1
Kolb, M.2
Stuber, V.3
Kruis, W.4
-
73
-
-
0029866680
-
Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids
-
Hirano,F., Tanaka,H., Makino,Y., Okamoto,K., Hiramoto,M., Handa,H. and Makino,I. (1996) Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. Carcinogenesis, 17, 427-433.
-
(1996)
Carcinogenesis
, vol.17
, pp. 427-433
-
-
Hirano, F.1
Tanaka, H.2
Makino, Y.3
Okamoto, K.4
Hiramoto, M.5
Handa, H.6
Makino, I.7
-
74
-
-
0033795966
-
Effects of specific bile acids on c-fos messenger RNA levels in human colon carcinoma Caco-2 cells
-
Di Toro,R., Campana,G., Murari,G. and Spampinato,S. (2000) Effects of specific bile acids on c-fos messenger RNA levels in human colon carcinoma Caco-2 cells. Eur. J. Pharm. Sci., 11, 291-298.
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
, pp. 291-298
-
-
Di Toro, R.1
Campana, G.2
Murari, G.3
Spampinato, S.4
-
75
-
-
0034685773
-
Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling
-
Qiao,D., Chen,W., Stratagouleas,E.D. and Martinez,J.D. (2000) Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling. J. Biol. Chem., 275, 15090-15098.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15090-15098
-
-
Qiao, D.1
Chen, W.2
Stratagouleas, E.D.3
Martinez, J.D.4
-
76
-
-
0036258704
-
Deoxycholic acid causes DNA damage in colonic cells with subsequent induction of caspases, COX-2 promoter activity and the transcription factors NF-κB and AP-1
-
Glinghammar,B., Inoue,H. and Rafter,J.J. (2002) Deoxycholic acid causes DNA damage in colonic cells with subsequent induction of caspases, COX-2 promoter activity and the transcription factors NF-κB and AP-1. Carcinogenesis, 23, 839-845.
-
(2002)
Carcinogenesis
, vol.23
, pp. 839-845
-
-
Glinghammar, B.1
Inoue, H.2
Rafter, J.J.3
-
77
-
-
0037071834
-
Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis
-
1583
-
Qiao,D., Im,E., Qi,W. and Martinez,J.D. (2002) Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis. Biochim. Biophys. Acta, 1583, 108-116.
-
(2002)
Biochim. Biophys. Acta
, pp. 108-116
-
-
Qiao, D.1
Im, E.2
Qi, W.3
Martinez, J.D.4
-
78
-
-
0028911047
-
Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes
-
Kwo,P., Patel,T., Bronk,S.F. and Gores,G.J. (1995) Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes. Am. J. Physiol., 268, G613-G621.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Kwo, P.1
Patel, T.2
Bronk, S.F.3
Gores, G.J.4
-
79
-
-
0028859161
-
Apoptosis in colorectal tumour cells: Induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate
-
Hague,A., Elder,D.J.E., Hicks,D.J. and Paraskeva,C. (1995) Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int. J. Cancer, 60, 400-406.
-
(1995)
Int. J. Cancer
, vol.60
, pp. 400-406
-
-
Hague, A.1
Elder, D.J.E.2
Hicks, D.J.3
Paraskeva, C.4
-
80
-
-
0029836555
-
Bile acid activation of the gadd153 promoter and of p53-independent apoptosis: Relevance to colon cancer
-
Zheng,Z.-Y., Bernstein,H., Bernstein,C., Payne,C.M., Martinez,J.D. and Gerner,E.W. (1996) Bile acid activation of the gadd153 promoter and of p53-independent apoptosis: relevance to colon cancer. Cell Death Differ., 3, 407-414.
-
(1996)
Cell Death Differ.
, vol.3
, pp. 407-414
-
-
Zheng, Z.-Y.1
Bernstein, H.2
Bernstein, C.3
Payne, C.M.4
Martinez, J.D.5
Gerner, E.W.6
-
81
-
-
0030934505
-
Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms
-
Marchetti,C., Migliorati,G., Moraca,R., Riccardi,C., Nicoletti,I., Fabiani,R., Mastrandrea,V. and Morozzi,G. (1997) Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms. Cancer Lett., 114, 97-99.
-
(1997)
Cancer Lett.
, vol.114
, pp. 97-99
-
-
Marchetti, C.1
Migliorati, G.2
Moraca, R.3
Riccardi, C.4
Nicoletti, I.5
Fabiani, R.6
Mastrandrea, V.7
Morozzi, G.8
-
82
-
-
0032919402
-
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
-
Faubion,W.A., Guicciardi,M.E., Miyoshi,H., Bronk,S.F., Roberts,P.J., Svingen,P.A., Kaufmann,S.H. and Gores,G.J. (1999) Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J. Clin. Invest., 103, 137-145.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 137-145
-
-
Faubion, W.A.1
Guicciardi, M.E.2
Miyoshi, H.3
Bronk, S.F.4
Roberts, P.J.5
Svingen, P.A.6
Kaufmann, S.H.7
Gores, G.J.8
-
83
-
-
0033895525
-
Characterization of bile salt-induced apoptosis in colon cancer cell lines
-
Schlottman,K., Wachs,F.P., Krieg,R.C., Kullman,E, Scholmerich,J. and Rogler,G. (2000) Characterization of bile salt-induced apoptosis in colon cancer cell lines. Cancer Res., 60, 4270-4276.
-
(2000)
Cancer Res.
, vol.60
, pp. 4270-4276
-
-
Schlottman, K.1
Wachs, F.P.2
Krieg, R.C.3
Kullman, E.4
Scholmerich, J.5
Rogler, G.6
-
84
-
-
0034674886
-
Increased susceptibility of cells to inducible apoptosis during growth from early to late log phase: An important caveat for in vitro apoptosis research
-
Washo-Stultz,D., Crowley,C., Payne,C.M., Bernstein,C., Marek,S., Gerner,E.W. and Bernstein,H. (2000) Increased susceptibility of cells to inducible apoptosis during growth from early to late log phase: an important caveat for in vitro apoptosis research. Toxicol. Lett., 116, 199-207.
-
(2000)
Toxicol. Lett.
, vol.116
, pp. 199-207
-
-
Washo-Stultz, D.1
Crowley, C.2
Payne, C.M.3
Bernstein, C.4
Marek, S.5
Gerner, E.W.6
Bernstein, H.7
-
85
-
-
0028091169
-
Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria
-
Krahenbuhl,S., Talos,C., Fischer,S. and Reichen,J. (1994) Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria. Hepatology, 19, 471-479.
-
(1994)
Hepatology
, vol.19
, pp. 471-479
-
-
Krahenbuhl, S.1
Talos, C.2
Fischer, S.3
Reichen, J.4
-
86
-
-
0032171253
-
The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria
-
Shivaram,K.N., Winklhofer-Roob,B.M., Straka,M.S., Devereaux,M.W., Everson,G., Mierau,G.W. and Sokol,R.J. (1998) The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria. Free Rad. Biol. Med., 25, 480-492.
-
(1998)
Free Rad. Biol. Med.
, vol.25
, pp. 480-492
-
-
Shivaram, K.N.1
Winklhofer-Roob, B.M.2
Straka, M.S.3
Devereaux, M.W.4
Everson, G.5
Mierau, G.W.6
Sokol, R.J.7
-
87
-
-
0029123537
-
Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids
-
Sokol,R.J., Winklhofer-Roob,B.M., Devereaux,M.W. and McKim Jr.,J.M. (1995) Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology, 109, 1249-1256.
-
(1995)
Gastroenterology
, vol.109
, pp. 1249-1256
-
-
Sokol, R.J.1
Winklhofer-Roob, B.M.2
Devereaux, M.W.3
McKim J.M., Jr.4
-
88
-
-
0026590541
-
Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells
-
Schreck,R., Meier,B., Mannel,D.N., Droge,W. and Baeuerle,P.A. (1992) Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med., 175, 1181-1194.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1181-1194
-
-
Schreck, R.1
Meier, B.2
Mannel, D.N.3
Droge, W.4
Baeuerle, P.A.5
-
89
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
-
Beg,A.A., Sha,W.C., Bronson,R.T., Ghosh,S. and Baltimore,D. (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature, 376, 167-170.
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Ghosh, S.4
Baltimore, D.5
-
91
-
-
0032559962
-
Epidermal growth factor activation of NF-kappaB is mediated through IkappaBalpha degradation and intracellular free calcium
-
Sun,L. and Carpenter,G. (1998) Epidermal growth factor activation of NF-kappaB is mediated through IkappaBalpha degradation and intracellular free calcium. Oncogene, 16, 2095-2102.
-
(1998)
Oncogene
, vol.16
, pp. 2095-2102
-
-
Sun, L.1
Carpenter, G.2
-
92
-
-
0034682527
-
Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells
-
Biswas,D.K., Cruz,A.P., Gansberger,E. and Pardee,A.B. (2000) Epidermal growth factor-induced nuclear factor kappa B activation: a major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc. Natl Acad. Sci. USA, 97, 8542-8547.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8542-8547
-
-
Biswas, D.K.1
Cruz, A.P.2
Gansberger, E.3
Pardee, A.B.4
-
93
-
-
0036605053
-
Effects of pharmacologic antagonist of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines
-
Bancroft,C.C., Chen,Z., Yeh,J., Sunwoo,J.B., Yeh,N.T., Jackson,S., Jackson,C. and Van Waes,C. (2002) Effects of pharmacologic antagonist of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. Int. J. Cancer, 99,538-548.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 538-548
-
-
Bancroft, C.C.1
Chen, Z.2
Yeh, J.3
Sunwoo, J.B.4
Yeh, N.T.5
Jackson, S.6
Jackson, C.7
Van Waes, C.8
-
94
-
-
0030882666
-
Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation
-
Finco,T.S., Westwick,J.K., Norris,J.L., Beg,A.A., Der,C.J. and Baldwin Jr.,A.S. (1997) Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation. J. Biol. Chem., 272, 24113-24116.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24113-24116
-
-
Finco, T.S.1
Westwick, J.K.2
Norris, J.L.3
Beg, A.A.4
Der, C.J.5
Baldwin A.S., Jr.6
-
95
-
-
0033553466
-
Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways
-
Norris,J.L. and Baldwin Jr.,A.S. (1999) Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways. J. Biol. Chem., 274, 13841-13846.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13841-13846
-
-
Norris, J.L.1
Baldwin A.S., Jr.2
-
97
-
-
0036084173
-
Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells
-
Wu,W., Jaspers,I., Zhang,W., Graves,L.M. and Samet,J.M. (2002) Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol., 282, L1040-L1048.
-
(2002)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.282
-
-
Wu, W.1
Jaspers, I.2
Zhang, W.3
Graves, L.M.4
Samet, J.M.5
-
98
-
-
0037089516
-
Inhibition of radiation-induced nuclear factor-kappaB activation by an anti-Ras single-chain antibody fragment: Lack of involvement in radiosensitization
-
Russell,J.S., Raju,U., Gumin,G.J., Lang,F.F., Wilson,D.R., Huet,T. and Tofilon,P.J. (2002) Inhibition of radiation-induced nuclear factor-kappaB activation by an anti-Ras single-chain antibody fragment: lack of involvement in radiosensitization. Cancer Res., 62, 2318-2326.
-
(2002)
Cancer Res.
, vol.62
, pp. 2318-2326
-
-
Russell, J.S.1
Raju, U.2
Gumin, G.J.3
Lang, F.F.4
Wilson, D.R.5
Huet, T.6
Tofilon, P.J.7
-
99
-
-
0035793566
-
Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway
-
Wang,D. and Richmond,A. (2001) Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway. J. Biol. Chem., 276, 3650-3659.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3650-3659
-
-
Wang, D.1
Richmond, A.2
-
100
-
-
0030695187
-
Phosphatidylinositol kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFκB and AP-1 activation
-
Reddy, S.A.G., Huang,J.H. and Liao,W.S.L. (1997) Phosphatidylinositol kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFκB and AP-1 activation. J. Biol. Chem., 272, 29167-29173.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29167-29173
-
-
Reddy, S.A.G.1
Huang, J.H.2
Liao, W.S.L.3
-
101
-
-
0036086234
-
A role for PKC-delta and PI 3-kinase in TNF-alpha-mediated antiapoptotic signaling in the human neutrophil
-
Kilpatrick,L.E., Lee,J.Y., Haines,K.M., Campbell,D.E., Sullivan,K.E. and Korchak,H.M. (2002) A role for PKC-delta and PI 3-kinase in TNF-alpha-mediated antiapoptotic signaling in the human neutrophil. Am. J. Physiol. Cell Physiol., 283, C48-C57.
-
(2002)
Am. J. Physiol. Cell Physiol.
, vol.283
-
-
Kilpatrick, L.E.1
Lee, J.Y.2
Haines, K.M.3
Campbell, D.E.4
Sullivan, K.E.5
Korchak, H.M.6
-
102
-
-
85047699031
-
Identification of signal transduction pathways involved in constitutive NF-kappaB activation in breast cancer cells
-
Bhat-Nakshatri,P., Sweeney,C.J. and Nakshatri,H. (2002) Identification of signal transduction pathways involved in constitutive NF-kappaB activation in breast cancer cells. Oncogene, 21, 2066-2078.
-
(2002)
Oncogene
, vol.21
, pp. 2066-2078
-
-
Bhat-Nakshatri, P.1
Sweeney, C.J.2
Nakshatri, H.3
-
103
-
-
0028176502
-
zeta PKC induces phosphorylation and inactivation of IκB-alpha in vitro
-
Diaz-Meco,M.T., Dominguez,I., Sanz,L., Dent,P., Lozano,J., Minicio,M.M., Berra,E., Hay,R.T., Sturgill,T.W. and Moscat,J. (1994) zeta PKC induces phosphorylation and inactivation of IκB-alpha in vitro. EMBO J., 13, 2842-2848.
-
(1994)
EMBO J.
, vol.13
, pp. 2842-2848
-
-
Diaz-Meco, M.T.1
Dominguez, I.2
Sanz, L.3
Dent, P.4
Lozano, J.5
Minicio, M.M.6
Berra, E.7
Hay, R.T.8
Sturgill, T.W.9
Moscat, J.10
-
104
-
-
0032588389
-
Activation of IkappaB kinase beta by protein kinase C isoforms
-
Lallena,M.J., Diaz-Meco,M.T., Bren,G., Paya,C.V. and Moscat,J. (1999) Activation of IkappaB kinase beta by protein kinase C isoforms. Mol. Cell. Biol., 19, 2180-2188.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 2180-2188
-
-
Lallena, M.J.1
Diaz-Meco, M.T.2
Bren, G.3
Paya, C.V.4
Moscat, J.5
-
105
-
-
0027965006
-
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase
-
Lozano,J., Berra,E., Municio,M.M., Diaz-Meco,M.T., Dominguez,I., Sanz,L. and Moscat,J. (1994) Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. J. Biol. Chem., 269, 19200-19202.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 19200-19202
-
-
Lozano, J.1
Berra, E.2
Municio, M.M.3
Diaz-Meco, M.T.4
Dominguez, I.5
Sanz, L.6
Moscat, J.7
-
106
-
-
0033153320
-
The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation
-
Sanz,L., Sanchez,P., Lallena,M.J., Diaz-Meco,M.T. and Moscat,J. (1999) The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. EMBO J., 18, 3044-3053.
-
(1999)
EMBO J.
, vol.18
, pp. 3044-3053
-
-
Sanz, L.1
Sanchez, P.2
Lallena, M.J.3
Diaz-Meco, M.T.4
Moscat, J.5
-
107
-
-
0034599476
-
The atypical PKC-interacting protein p62 channels NF-kappaB activation by the II-1-TRAF6 pathway
-
Sanz,L., Diaz-Meco,M.T., Nakano,H. and Moscat,J. (2000) The atypical PKC-interacting protein p62 channels NF-kappaB activation by the II-1-TRAF6 pathway. EMBO J., 19, 1576-1586.
-
(2000)
EMBO J.
, vol.19
, pp. 1576-1586
-
-
Sanz, L.1
Diaz-Meco, M.T.2
Nakano, H.3
Moscat, J.4
-
108
-
-
13944253118
-
Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway
-
Leitges,M., Sanz,L., Martin,P., Duran,A., Braun,U., Garcia,J.F., Camacho,F., Diaz-Meco,M.T., Rennert,P.D. and Moscat,J. (2001) Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway. Mol. Cell, 8, 771-780.
-
(2001)
Mol. Cell
, vol.8
, pp. 771-780
-
-
Leitges, M.1
Sanz, L.2
Martin, P.3
Duran, A.4
Braun, U.5
Garcia, J.F.6
Camacho, F.7
Diaz-Meco, M.T.8
Rennert, P.D.9
Moscat, J.10
-
109
-
-
0034602146
-
The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis
-
Foehr,E.D., Bohuslav,J., Chen,L.F., DeNoronha,C., Geleziunas,R., Lin,X., O'Mahony,A. and Greene,W.C. (2000) The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis. J. Biol. Chem., 275, 34021-34024.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34021-34024
-
-
Foehr, E.D.1
Bohuslav, J.2
Chen, L.F.3
DeNoronha, C.4
Geleziunas, R.5
Lin, X.6
O'Mahony, A.7
Greene, W.C.8
-
110
-
-
0035937845
-
The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome
-
Habib,A.A., Chatterjee,S., Park,S.K., Ratan,R.R., Lefebvre,S. and Vartanian,T. (2001) The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome. J. Biol. Chem., 276, 8865-8874.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8865-8874
-
-
Habib, A.A.1
Chatterjee, S.2
Park, S.K.3
Ratan, R.R.4
Lefebvre, S.5
Vartanian, T.6
-
111
-
-
0037040901
-
A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells
-
Dhawan,P. and Richmond,A. (2002) A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells. J. Biol. Chem., 277, 7920-7928.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7920-7928
-
-
Dhawan, P.1
Richmond, A.2
-
112
-
-
0037086155
-
Atypical protein kinase C zeta as a target for chemosensitization of tumor cells
-
Filomenko,R., Poirson-Buchat,F., Billerey,C., Belon,J.-P., Garrido,C., Solary,E. and Bettaieb,A. (2002) Atypical protein kinase C zeta as a target for chemosensitization of tumor cells. Cancer Res., 62, 1815-1821.
-
(2002)
Cancer Res.
, vol.62
, pp. 1815-1821
-
-
Filomenko, R.1
Poirson-Buchat, F.2
Billerey, C.3
Belon, J.-P.4
Garrido, C.5
Solary, E.6
Bettaieb, A.7
-
113
-
-
0033579569
-
Aminosalicylic acid inhibits IκB kinase a phosphorylation of IκBa in mouse intestinal epithelial cells
-
Yan,F. and Polk,D.B. (1999) Aminosalicylic acid inhibits IκB kinase a phosphorylation of IκBa in mouse intestinal epithelial cells. J. Biol. Chem., 274, 36631-36636.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36631-36636
-
-
Yan, F.1
Polk, D.B.2
-
114
-
-
0034190367
-
Recent advances towards understanding redox mechanisms in the activation of nuclear factor κB
-
Janssen-Heininger,Y.M.W., Poynter,M.E. and Baeuerle,P.A. (2000) Recent advances towards understanding redox mechanisms in the activation of nuclear factor κB. Free Rad. Biol. Med., 28, 1317-1327.
-
(2000)
Free Rad. Biol. Med.
, vol.28
, pp. 1317-1327
-
-
Janssen-Heininger, Y.M.W.1
Poynter, M.E.2
Baeuerle, P.A.3
-
115
-
-
1842295744
-
Regulatory role for a novel human thioredoxin peroxidase in NF-κB activation
-
Jin,D.-Y., Chae,H.Z., Rhee,S.G. and Jeang,K.-T. (1997) Regulatory role for a novel human thioredoxin peroxidase in NF-κB activation. J. Biol. Chem., 272, 30952-30961.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30952-30961
-
-
Jin, D.-Y.1
Chae, H.Z.2
Rhee, S.G.3
Jeang, K.-T.4
-
116
-
-
0033301995
-
From cytoprotection to tumor suppression: The mutlifactorial role of peroxiredoxins
-
Butterfield,L.H., Merino,A., Golub,S.H. and Shau,H. (1999) From cytoprotection to tumor suppression: the mutlifactorial role of peroxiredoxins. Antioxid. Redox Signal., 1, 385-402.
-
(1999)
Antioxid. Redox Signal.
, vol.1
, pp. 385-402
-
-
Butterfield, L.H.1
Merino, A.2
Golub, S.H.3
Shau, H.4
-
117
-
-
0030692005
-
Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2
-
Zhang,P., Liu,B., Kang,S.W., Seo,M.S., Rhee,S.G. and Obeid,L.M. (1997) Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2. J. Biol. Chem., 272, 30615-30618.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30615-30618
-
-
Zhang, P.1
Liu, B.2
Kang, S.W.3
Seo, M.S.4
Rhee, S.G.5
Obeid, L.M.6
-
118
-
-
0034708217
-
Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis
-
Zhou,Y., Kok,K.H., Chun,A.C., Wong,C.M., Wu,H.W., Lin,M.C., Fung,P.C., Kung,H. and Jin,D.Y. (2000) Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis. Biochem. Biophys. Res. Commun., 268, 921-927.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.268
, pp. 921-927
-
-
Zhou, Y.1
Kok, K.H.2
Chun, A.C.3
Wong, C.M.4
Wu, H.W.5
Lin, M.C.6
Fung, P.C.7
Kung, H.8
Jin, D.Y.9
-
119
-
-
0034674703
-
Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells
-
Kim,H., Lee,T.H., Park,E.S., Suh,J.M., Park,S.J., Chung,H.K., Kwon,O.Y., Kim,Y.K., Ro,H.K. and Shong,M. (2000) Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells. J. Biol. Chem., 275, 18266-18270.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18266-18270
-
-
Kim, H.1
Lee, T.H.2
Park, E.S.3
Suh, J.M.4
Park, S.J.5
Chung, H.K.6
Kwon, O.Y.7
Kim, Y.K.8
Ro, H.K.9
Shong, M.10
-
120
-
-
0035425182
-
Thioredoxin peroxidase-1 (peroxiredoxin-1) is increased in thioredoxin-1 transfected cells and results in enhanced protection against apoptosis caused by hydrogen peroxide but not by other agents including dexamethasone, etoposide and doxorubicin
-
Berggren,M.I., Husbeck,B., Samulitis,B., Baker,A.F., Gallegos,A. and Powis,G. (2001) Thioredoxin peroxidase-1 (peroxiredoxin-1) is increased in thioredoxin-1 transfected cells and results in enhanced protection against apoptosis caused by hydrogen peroxide but not by other agents including dexamethasone, etoposide and doxorubicin. Arch. Biochem. Biophys 392, 103-109.
-
(2001)
Arch. Biochem. Biophys.
, vol.392
, pp. 103-109
-
-
Berggren, M.I.1
Husbeck, B.2
Samulitis, B.3
Baker, A.F.4
Gallegos, A.5
Powis, G.6
-
121
-
-
0030885421
-
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control
-
Chu,Z.L., McKinsey,T.A., Liu,L., Gentry,J.J., Malim,M.H. and Ballard,D.W. (1997) Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. Proc. Natl Acad. Sci. USA, 94, 10057-10062.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10057-10062
-
-
Chu, Z.L.1
McKinsey, T.A.2
Liu, L.3
Gentry, J.J.4
Malim, M.H.5
Ballard, D.W.6
-
122
-
-
0032508414
-
NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang,C.Y., Mayo,M.W., Komeluk,R.G., Goeddel,D.V. and Baldwin Jr.,A.S. (1998) NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 281, 1680-1683.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Komeluk, R.G.3
Goeddel, D.V.4
Baldwin A.S., Jr.5
-
123
-
-
0035976997
-
NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene
-
Kurland,J.F., Kodym,R., Story,M.D., Spurgers,K.B., McDonnell,T.J. and Meyn,R.E. (2001) NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. J. Biol. Chem., 276, 45380-45386.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45380-45386
-
-
Kurland, J.F.1
Kodym, R.2
Story, M.D.3
Spurgers, K.B.4
McDonnell, T.J.5
Meyn, R.E.6
-
124
-
-
0035504081
-
Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer
-
Catz,S.D. and Johnson,J.L. (2001) Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer. Oncogene, 20, 7342-7351.
-
(2001)
Oncogene
, vol.20
, pp. 7342-7351
-
-
Catz, S.D.1
Johnson, J.L.2
-
125
-
-
0037198274
-
NF-kappaB activates Bcl-2 expression in t (14;18) lymphoma cells
-
Heckman,C.A., Mehew,J.W. and Boxer,L.M. (2002) NF-kappaB activates Bcl-2 expression in t (14;18) lymphoma cells. Oncogene, 21, 3898-3908.
-
(2002)
Oncogene
, vol.21
, pp. 3898-3908
-
-
Heckman, C.A.1
Mehew, J.W.2
Boxer, L.M.3
-
126
-
-
0035212795
-
The specific NOS2 inhibitor, 1400W, sensitizes HepG2 cells to genotoxic, oxidative, xenobiotic and endoplasmic reticulum stresses
-
Payne,C.M., Bernstein,H., Bernstein,C., Kunke,K. and Garewal,H. (2001) The specific NOS2 inhibitor, 1400W, sensitizes HepG2 cells to genotoxic, oxidative, xenobiotic and endoplasmic reticulum stresses. Antiox. Redox Signaling, 3, 931-936.
-
(2001)
Antiox. Redox Signaling
, vol.3
, pp. 931-936
-
-
Payne, C.M.1
Bernstein, H.2
Bernstein, C.3
Kunke, K.4
Garewal, H.5
-
127
-
-
0036223475
-
Tetrahydrobiopterin in nitric oxide synthesis: A novel biological role for pteridines
-
Gorren,A.C. and Mayer,B. (2002) Tetrahydrobiopterin in nitric oxide synthesis: a novel biological role for pteridines. Curr. Drug Metab., 3, 133-157.
-
(2002)
Curr. Drug Metab.
, vol.3
, pp. 133-157
-
-
Gorren, A.C.1
Mayer, B.2
-
128
-
-
0035891543
-
Thioredoxin reductase-its role in epidermal redox status
-
Schallreuter,K.U. and Wood,J.M. (2001) Thioredoxin reductase-its role in epidermal redox status. J. Photochem. Photobiol. B, 64, 179-184.
-
(2001)
J. Photochem. Photobiol. B
, vol.64
, pp. 179-184
-
-
Schallreuter, K.U.1
Wood, J.M.2
-
129
-
-
0036468241
-
Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate
-
Patel,K.B., Stratford,M.R., Wardman,P. and Everett,S.A. (2002) Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate. Free Rad. Biol. Med., 32, 203-211.
-
(2002)
Free Rad. Biol. Med.
, vol.32
, pp. 203-211
-
-
Patel, K.B.1
Stratford, M.R.2
Wardman, P.3
Everett, S.A.4
-
131
-
-
0037066710
-
Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO
-
Kroncke,K.-D., Klotz,L.-O., Suschek,C.V. and Sies,H. (2002) Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO. J. Biol. Chem., 277, 13294-13301.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13294-13301
-
-
Kroncke, K.-D.1
Klotz, L.-O.2
Suschek, C.V.3
Sies, H.4
-
132
-
-
0037013206
-
A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein NIP3, leading to cellular apoptosis
-
Mizutani,A., Furukawa,T., Adachi,Y., Ikehara,S. and Taketani,S. (2002) A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein NIP3, leading to cellular apoptosis. J. Biol. Chem., 277, 15851-15858.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15851-15858
-
-
Mizutani, A.1
Furukawa, T.2
Adachi, Y.3
Ikehara, S.4
Taketani, S.5
-
133
-
-
0030834975
-
Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase
-
Sies,H., Sharov,V.S., Klotz,L.O. and Briviba,K. (1997) Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase. J. Biol. Chem., 272, 27812-27817.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27812-27817
-
-
Sies, H.1
Sharov, V.S.2
Klotz, L.O.3
Briviba, K.4
-
134
-
-
0034488154
-
Selenoprotein P
-
Moschos,M.P. (2000) Selenoprotein P. Cell Mol. Life Sci., 57, 1836-1845.
-
(2000)
Cell Mol. Life Sci.
, vol.57
, pp. 1836-1845
-
-
Moschos, M.P.1
-
135
-
-
0034656845
-
Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics
-
Sies,H. and Arteel,G.E. (2000) Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics. Free Rad. Biol. Med., 28, 1451-1455.
-
(2000)
Free Rad. Biol. Med.
, vol.28
, pp. 1451-1455
-
-
Sies, H.1
Arteel, G.E.2
-
136
-
-
0036129525
-
Activation of the metallothionein IIA promoter and other key stress response elements by ursodeoxycholate in HepG2 cells: Relevance to the cytoprotective function of ursodeoxycholate
-
Bernstein,C., Payne,C.M., Bernstein,H. and Garewal,H. (2002) Activation of the metallothionein IIA promoter and other key stress response elements by ursodeoxycholate in HepG2 cells: relevance to the cytoprotective function of ursodeoxycholate. Pharmacol., 65, 2-9.
-
(2002)
Pharmacol.
, vol.65
, pp. 2-9
-
-
Bernstein, C.1
Payne, C.M.2
Bernstein, H.3
Garewal, H.4
-
137
-
-
0031950282
-
Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
-
Rodrigues,C.M.P., Fan,G., Wong,P.Y., Kren,B.T. and Steer,C.J. (1998) Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol. Med., 4, 165-178.
-
(1998)
Mol. Med.
, vol.4
, pp. 165-178
-
-
Rodrigues, C.M.P.1
Fan, G.2
Wong, P.Y.3
Kren, B.T.4
Steer, C.J.5
-
138
-
-
0034671886
-
Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage
-
Cai,L., Klein,J.B. and Kang,Y.J. (2000) Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage. J. Biol. Chem., 275, 38957-38960.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38957-38960
-
-
Cai, L.1
Klein, J.B.2
Kang, Y.J.3
-
139
-
-
0035956862
-
Zinc metallothionein imported into liver mitochondria modulates respiration
-
Ye,B., Maret,W. and Vallee,B.L. (2001) Zinc metallothionein imported into liver mitochondria modulates respiration. Proc. Natl Acad. Sci. USA, 98, 2317-2322.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2317-2322
-
-
Ye, B.1
Maret, W.2
Vallee, B.L.3
-
140
-
-
0034602705
-
Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein
-
Pearce,L.L., Gandley,R.E., Han,W., Wasserloos,K., Stitt,M., Kanai,A.J., McLaughlin,M.K., Pitt,B.R. and Levitan,E.S. (2000) Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein. Proc. Natl Acad. Sci. USA, 97, 477-482.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 477-482
-
-
Pearce, L.L.1
Gandley, R.E.2
Han, W.3
Wasserloos, K.4
Stitt, M.5
Kanai, A.J.6
McLaughlin, M.K.7
Pitt, B.R.8
Levitan, E.S.9
-
141
-
-
0021367846
-
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
-
Cohen,J.J. and Duke,R.C. (1984) Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J. Immunol., 132, 38-42.
-
(1984)
J. Immunol.
, vol.132
, pp. 38-42
-
-
Cohen, J.J.1
Duke, R.C.2
-
142
-
-
0030855488
-
Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis
-
Perry,D.K., Smyth,M.J., Stennicke,H.R., Salvesen,G.S., Duriez,P., Poirier,G.G. and Hannun,Y.A. (1997) Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis. J. Biol. Chem., 272, 18530-18533.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18530-18533
-
-
Perry, D.K.1
Smyth, M.J.2
Stennicke, H.R.3
Salvesen, G.S.4
Duriez, P.5
Poirier, G.G.6
Hannun, Y.A.7
-
143
-
-
0033984094
-
BNIP3 heterodimerizes with Bcl-2/Bcl-XL and induces cell death independent of a bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites
-
Ray,R., Chen,G., Vande Velde,C., Cizeau,J., Park,J.H., Reed,J.C., Gietz,R.D. and Greenberg,A.H. (2000) BNIP3 heterodimerizes with Bcl-2/Bcl-XL and induces cell death independent of a bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites. J. Biol. Chem., 275, 1439-1448.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1439-1448
-
-
Ray, R.1
Chen, G.2
Vande Velde, C.3
Cizeau, J.4
Park, J.H.5
Reed, J.C.6
Gietz, R.D.7
Greenberg, A.H.8
-
144
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis
-
Kluck,R.M., Bossy-Wetzel,E., Green,D.R. and Newmeyer,D.D. (1997) The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis. Science, 275, 1132-1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
145
-
-
0036478928
-
The Apaf-1 apoptosome: A large caspase-activating complex
-
Cain,K., Bratton,S.B. and Cohen,G.M. (2002) The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie, 84, 203-214.
-
(2002)
Biochimie
, vol.84
, pp. 203-214
-
-
Cain, K.1
Bratton, S.B.2
Cohen, G.M.3
-
146
-
-
0032885388
-
Mammalian caspases: Structure, activation, substrates and functions during apoptosis
-
Earnshaw,W.C., Martins,L.M. and Kaufmann,S.H. (1999) Mammalian caspases: structure, activation, substrates and functions during apoptosis. Annu. Rev. Biochem., 68, 383-424.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
147
-
-
0032785021
-
Caspase structure, proteolytic substrates and function during apoptotic cell death
-
Nicholson,D.W. (1999) Caspase structure, proteolytic substrates and function during apoptotic cell death. Cell Death Differ., 6, 1028-1042.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
148
-
-
0034615555
-
Caspases-controlling intracellular signals by protease zymogen activation
-
1477
-
Stennicke,H.R. and Salveson,G.S. (2000) Caspases-controlling intracellular signals by protease zymogen activation. Biochim. Biophys. Acta, 1477, 299-306.
-
(2000)
Biochim. Biophys. Acta
, pp. 299-306
-
-
Stennicke, H.R.1
Salveson, G.S.2
-
149
-
-
0034501628
-
The tumor microenvironment as a determinant of cancer cell survival: A possible mechanism for de novo drug resistance
-
Shain,K.H., Landowski,T.H. and Dalton,W.S. (2000) The tumor microenvironment as a determinant of cancer cell survival: a possible mechanism for de novo drug resistance. Curr. Opin. Oncol., 12, 557-563.
-
(2000)
Curr. Opin. Oncol.
, vol.12
, pp. 557-563
-
-
Shain, K.H.1
Landowski, T.H.2
Dalton, W.S.3
-
150
-
-
0032250184
-
Serpins and regulation of cell death
-
Bird,P.I. (1998) Serpins and regulation of cell death. Results Probl. Cell. Diff., 24, 63-89.
-
(1998)
Results Probl. Cell Diff.
, vol.24
, pp. 63-89
-
-
Bird, P.I.1
-
151
-
-
0034096190
-
p53 regulates the expression of the tumor suppressor gene maspin
-
Zou,Z., Gao,C., Nagaich,A.K., Connell,T., Saito,S., Moul,J.W., Seth,P., Appella,E. and Srivastava,S. (2000) p53 regulates the expression of the tumor suppressor gene maspin. J. Biol. Chem., 275, 6051-6054.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6051-6054
-
-
Zou, Z.1
Gao, C.2
Nagaich, A.K.3
Connell, T.4
Saito, S.5
Moul, J.W.6
Seth, P.7
Appella, E.8
Srivastava, S.9
-
152
-
-
0023871942
-
Oncogenes and tumor-suppressing genes
-
Friend,S.H., Dryja,T.P. and Weinberg,R.A. (1988) Oncogenes and tumor-suppressing genes. N. Engl. J. Med., 318, 618-622.
-
(1988)
N. Engl. J. Med.
, vol.318
, pp. 618-622
-
-
Friend, S.H.1
Dryja, T.P.2
Weinberg, R.A.3
-
153
-
-
0036270993
-
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: Fail-safe protection against carcinogenesis
-
Bernstein,C., Bernstein,H., Payne,C.M. and Garewal,H. (2002) DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat. Res., 511, 145-178.
-
(2002)
Mutat. Res.
, vol.511
, pp. 145-178
-
-
Bernstein, C.1
Bernstein, H.2
Payne, C.M.3
Garewal, H.4
-
154
-
-
85047699958
-
Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells
-
Katsuda,K., Kataoka,M., Uno,F., Murakami,T., Kondo,T., Roth,J.A., Tanaka,N. and Fujiwara,T. (2002) Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells. Oncogene, 21, 2108-2113.
-
(2002)
Oncogene
, vol.21
, pp. 2108-2113
-
-
Katsuda, K.1
Kataoka, M.2
Uno, F.3
Murakami, T.4
Kondo, T.5
Roth, J.A.6
Tanaka, N.7
Fujiwara, T.8
-
155
-
-
0036467582
-
The role of p53 and pRB in apoptosis and cancer
-
Hickman,E.S., Moroni,M.C. and Helin,K. (2002) The role of p53 and pRB in apoptosis and cancer. Curr. Opin. Genet. Dev., 12, 60-66.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 60-66
-
-
Hickman, E.S.1
Moroni, M.C.2
Helin, K.3
-
156
-
-
0025382820
-
Transport and assembly processes in the endoplasmic reticulum
-
Gething,M.J. and Sambrook,J. (1990) Transport and assembly processes in the endoplasmic reticulum. Semin. Cell Biol., 1, 65-72.
-
(1990)
Semin. Cell Biol.
, vol.1
, pp. 65-72
-
-
Gething, M.J.1
Sambrook, J.2
-
157
-
-
0033027714
-
Is the cell death pathway triggered by the mitochondrion or the endoplasmic reticulum?
-
Siesjo,B.K., Hu,B. and Kristian,T. (1999) Is the cell death pathway triggered by the mitochondrion or the endoplasmic reticulum? J. Cerebral Blood Flow Metab., 19, 19-26.
-
(1999)
J. Cerebral Blood Flow Metab.
, vol.19
, pp. 19-26
-
-
Siesjo, B.K.1
Hu, B.2
Kristian, T.3
-
158
-
-
0035736259
-
Organelle-specific inititation of cell death pathways
-
Ferri,K.F. and Kroemer,G. (2001) Organelle-specific inititation of cell death pathways. Nature Cell Biol., 3, E255-E263.
-
(2001)
Nature Cell Biol.
, vol.3
-
-
Ferri, K.F.1
Kroemer, G.2
-
159
-
-
0033956949
-
Mitochondria and cell death
-
Halestrap,A.P., Doran,E., Gillespie,J.P. and O'Toole,A. (2000) Mitochondria and cell death. Biochem. Soc. Trans., 28, 170-177.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 170-177
-
-
Halestrap, A.P.1
Doran, E.2
Gillespie, J.P.3
O'Toole, A.4
-
160
-
-
0034068601
-
Mitochondrial control of cell death
-
Kroemer,G. and Reed,J.C. (2000) Mitochondrial control of cell death. Nature Medicine, 6, 513-519.
-
(2000)
Nature Medicine
, vol.6
, pp. 513-519
-
-
Kroemer, G.1
Reed, J.C.2
-
161
-
-
0032440847
-
Heat shock proteins: Regulators of stress response and apoptosis
-
Samali,A. and Orrenius,S. (1998) Heat shock proteins: regulators of stress response and apoptosis. Cell Stress Chaperones, 3, 228-236.
-
(1998)
Cell Stress Chaperones
, vol.3
, pp. 228-236
-
-
Samali, A.1
Orrenius, S.2
-
162
-
-
0033862082
-
Bile acids increase intracellular Ca (2+) concentration and nitric oxide production in vascular endothelial cells
-
Nakajima,T., Okuda,Y., Chisaki,K., Shin,W.S., Iwasawa,K., Morita,T., Matsumoto,A., Suzuki,J.I., Suzuki,S., Yamada,N., Toyo-Oka,T., Nagai,R. and Omata,M. (2000) Bile acids increase intracellular Ca (2+) concentration and nitric oxide production in vascular endothelial cells. Br. J. Pharmacol., 130, 1457-1467.
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1457-1467
-
-
Nakajima, T.1
Okuda, Y.2
Chisaki, K.3
Shin, W.S.4
Iwasawa, K.5
Morita, T.6
Matsumoto, A.7
Suzuki, J.I.8
Suzuki, S.9
Yamada, N.10
Toyo-Oka, T.11
Nagai, R.12
Omata, M.13
-
163
-
-
0036554826
-
Bile acids induce calcium signals in mouse pancreatic acinar cells: Implications for bile-induced pancreatic pathology
-
Voronina,S., Longbottom,R., Sutton,R., Petersen,O.H. and Tepikin,A. (2002) Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology. J. Physiol., 540, 49-55.
-
(2002)
J. Physiol.
, vol.540
, pp. 49-55
-
-
Voronina, S.1
Longbottom, R.2
Sutton, R.3
Petersen, O.H.4
Tepikin, A.5
-
164
-
-
0027227827
-
Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium
-
Spivey,J.R., Bronk,S.F. and Gores,G.J. (1993) Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium. J. Clin. Invest., 92, 17-24.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 17-24
-
-
Spivey, J.R.1
Bronk, S.F.2
Gores, G.J.3
-
165
-
-
18344388462
-
Coupling endoplasmic reticulum stress to the cell death program: Role of the ER chaperone GRP78
-
Rao,R.V., Peel,A., Logvinova,A., del Rio,G., Hermel,E., Yokota,T., Goldsmith,P.C., Ellerby,L.M., Ellerby,H.M. and Bredesen,D.E. (2002) Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78. FEBS Lett., 514, 122-128.
-
(2002)
FEBS Lett.
, vol.514
, pp. 122-128
-
-
Rao, R.V.1
Peel, A.2
Logvinova, A.3
del Rio, G.4
Hermel, E.5
Yokota, T.6
Goldsmith, P.C.7
Ellerby, L.M.8
Ellerby, H.M.9
Bredesen, D.E.10
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