The Bile Acid Glycochenodeoxycholate Induces TRAIL-Receptor 2/DR5 Expression and Apoptosis

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 38610-38618

  Higuchi, Hajime ^a   Bronk, Steven F ^a   Takikawa, Yasuhiro ^a   Werneburg, Nathan ^a   Takimoto, Rishu ^b   El Deiry, Wafik ^b   Gores, Gregory J ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; ENZYME INHIBITION; POLYPEPTIDES; TUMORS;

TRANSFECTED;

ENZYMES;

BILE ACID; CASPASE 8; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GLYCOCHENODEOXYCHOLIC ACID; POLYPEPTIDE; PROTEIN; SODIUM; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 9; ENZYME INHIBITOR; LIGAND; LUCIFERASE; MEMBRANE PROTEIN; MESSENGER RNA; TNFRSF10B PROTEIN, HUMAN; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL CULTURE; CELL FRACTIONATION; DOMINANT GENE; DOSE RESPONSE; DRUG ANTAGONISM; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; MITOCHONDRION; PHYSIOLOGY; PLASMID; REPORTER GENE; SERODIAGNOSIS; TIME; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENES, DOMINANT; GENES, REPORTER; GLYCOCHENODEOXYCHOLIC ACID; HEPATOCYTES; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIGANDS; LUCIFERASES; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; MODELS, GENETIC; PLASMIDS; PRECIPITIN TESTS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBCELLULAR FRACTIONS; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0035914341     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105300200     Document Type: Article

References (48)

1. Greim, H., Trulzsch, D., Czygan, P., Rudick, J., Hutterer, F., Schaffner, F., and Popper, H. (1972) Gastroenterology 63, 846-850
2. Strautnieks, S. S., Bull, L. N., Knisely, A. S., Kocoshis, S. A., Dahl, N., Arnell, H., Sokal, E., Dahan, K., Childs, S., Ling, V., Tanner, M. S., Kagalwalla, A. F., Nemeth, A., Pawlowska, J., Baker, A., Mieli-Vergani, G., Freimer, N. B., Gardiner, R. M., and Thompson, R. J. (1998) Nat. Genet. 20, 233-238
3. Faubion, W. A., Guicciardi, M. E., Miyoshi, H., Bronk, S. F., Roberts, P. J., Svingen, P. A., Kaufmann, S. H., and Gores, G. J. (1999) J. Clin. Invest. 103, 137-145
4. Rodrigues, C. M., Fan, G., Wong, P. Y., Kren, B. T., and Steer, C. J. (1998) Mol. Med. 4, 165-178
5. Sodeman, T., Bronk, S. F., Roberts, P. J., Miyoshi, H., and Gores, G. J. (2000) Am. J. Physiol. Gastrointest. Liver Physiol. 278, G992-999
6. Miyoshi, H., Rust, C., Roberts, P. J., Burgart, L. J., and Gores, G. J. (1999) Gastroenterology 117, 669-677
7. Kuang, A. A., Diehl, G. E., Zhang, J., and Winoto, A. (2000) J. Biol. Chem. 275, 25065-25068
8. Schulze-Osthoff, K., Ferrari, D., Los, M., Wesselborg, S., and Peter, M. E. (1998) Eur. J. Biochem. 254, 439-459
9. Sprick, M. R., Weigand, M. A., Rieser, E., Rauch, C. T., Juo, P., Blenis, J., Krammer, P. H., and Walczak, H. (2000) Immunity 12, 599-609
10. Strasser, A., and Newton, K. (1999) Int. J. Biochem. Cell Biol. 31, 533-537
11. Wajant, H., Johannes, F. J., Haas, E., Siemienski, K., Schwenzer, R., Schubert, G., Weiss, T., Grell, M., and Scheurich, P. (1998) Curr. Biol. 8, 113-116
12. Scaffidi, C., Fulda, S., Srinivasan, A., Friesen, C., Li, F., Tomaselli, K. J., Debatin, K. M., Krammer, P. H., and Peter, M. E. (1998) EMBO J. 17, 1675-1687
13. Green, D. R., and Reed, J. C. (1998) Science 281, 1309-1312
14. Rodrigues, C. M., Ma, X., Linehan-Stieers, C., Fan, G., Kren, B. T., and Steer, C. J. (1999) Cell Death Differ. 6, 842-854
15. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
16. Kwo, P., Patel, T., Bronk, S. F., and Gores, G. J. (1995) Am. J. Physiol. 268, G613-621
17. Jones, B., Roberts, P. J., Faubion, W. A., Kominami, E., and Gores, G. J. (1998) Am. J. Physiol. 275, G723-730
18. Takimoto, R., and El-Deiry, W. S. (2000) Oncogene 19, 1735-1743
19. Roberts, L. R., Kurosawa, H., Bronk, S. F., Fesmier, P. J., Agellon, L. B., Leung, W. Y., Mao, F., and Gores, G. J. (1997) Gastroenterology 113, 1714-1726
20. Leist, M., Volbracht, C., Fava, E., and Nicotera, P. (1998) Mol. Pharmacol. 54, 789-801
21. Screaton, G. R., Mongkolsapaya, J., Xu, X. N., Cowper, A. E., McMichael, A. J., and Bell, J. I. (1997) Curr. Biol. 7, 693-696
22. Rust, C., Karnitz, L. M., Paya, C. V., Moscat, J., Simari, R. D., and Gores, G. J. (2000) J. Biol. Chem. 275, 20210-20216
23. Rodrigues, C. M., Fan, G., Ma, X., Kren, B. T., and Steer, C. J. (1998) J. Clin. Invest. 101, 2790-2799
24. Shima, Y., Nakao, K., Nakashima, T., Kawakami, A., Nakata, K., Hamasaki, K., Kato, Y., Eguchi, K., and Ishii, N. (1999) Hepatology 30, 1215-1222
25. Walczak, H., Degli-Esposti, M. A., Johnson, R. S., Smolak, P. J., Waugh, J. Y., Boiani, N., Timour, M. S., Gerhart, M. J., Schooley, K. A., Smith, C. A., Goodwin, R. G., and Rauch, C. T. (1997) EMBO J. 16, 5386-5397
26. Griffith, T. S., Chin, W. A., Jackson, G. C., Lynch, D. H., and Kubin, M. Z. (1998) J. Immunol. 161, 2833-2840
27. Leverkus, M., Neumann, M., Mengling, T., Rauch, C. T., Brocker, E. B., Krammer, P. H., and Walczak, H. (2000) Cancer Res. 60, 553-559
28. Kim, K., Takimoto, R., Dicker, D. T., Chen, Y., Gazitt, Y., and El-Deiry, W. S. (2001) Int. J. Oncol. 18, 241-247
29. Hao, C., Beguinot, F., Condorelli, G., Trencia, A., Van Meir, E. G., Yong, V. W., Parney, I. F., Roa, W. H., and Petruk, K. C. (2001) Cancer Res. 61, 1162-1170
30. Hymowitz, S. G., Christinger, H. W., Fuh, G., Ultsch, M., O'Connell, M., Kelley, R. F., Ashkenazi, A., and de Vos, A. M. (1999) Mol. Cell 4, 563-571
31. Hymowitz, S. G., O'Connell, M. P., Ultsch, M. H., Hurst, A., Totpal, K., Ashkenazi, A., de Vos, A. M., and Kelley, R. F. (2000) Biochemistry 39, 633-640
32. Aragane, Y., Kulms, D., Metze, D., Wilkes, G., Poppelmann, B., Luger, T. A., and Schwarz, T. (1998) J. Cell Biol. 140, 171-182
33. Rehemtulla, A., Hamilton, C. A., Chinnaiyan, A. M., and Dixit, V. M. (1997) J. Biol. Chem. 272, 25783-25786
34. Meier, P. J., Eckhardt, U., Schroeder, A., Hagenbuch, B., and Stieger, B. (1997) Hepatology 26, 1667-1677
35. Patel, T., Bronk, S. F., and Gores, G. J. (1994) J. Clin. Invest. 94, 2183-2192
36. Yerushalmi, B., Dahl, R., Devereaux, M. W., Gumpricht, E., and Sokol, R. J. (2001) Hepatology 33, 616-626
37. Jiang, Y., Woronicz, J. D., Liu, W., and Goeddel, D. V. (1999) Science 283, 543-546
38. Suzuki, A., Obata, S., Hayashida, M., Kawano, H., Nakano, T., and Shiraki, K. (2001) Nat. Med. 7, 88-93
39. Simons, K., and Ikonen, E. (1997) Nature 387, 569-572
40. Lawrence, D., Shahrokh, Z., Marsters, S., Achilles, K., Shih, D., Mounho, B., Hillan, K., Totpal, K., DeForge, L., Schow, P., Hooley, J., Sherwood, S., Pai, R., Leung, S., Khan, L., Gliniak, B., Bussiere, J., Smith, C. A., Strom, S. S., Kelley, S., Fox, J. A., Thomas, D., and Ashkenazi, A. (2001) Nat. Med. 7, 383-385
41. Meng, R. D., and El-Deiry, W. S. (2001) Exp. Cell Res. 262, 154-169
42. Sheikh, M. S., Burns, T. F., Huang, Y., Wu, G. S., Amundson, S., Brooks, K. S., Fornace, A. J., and el-Deiry, W. S. (1998) Cancer Res. 58, 1593-1598
43. Hsu, I. C., Tokiwa, T., Bennett, W., Metcalf, R. A., Welsh, J. A., Sun, T., and Harris, C. C. (1993) Carcinogenesis 14, 987-992
44. Parks, D. J., Blanchard, S. G., Bledsoe, R. K., Chandra, G., Consler, T. G., Kliewer, S. A., Stimmel, J. B., Willson, T. M., Zavacki, A. M., Moore, D. D., and Lehmann, J. M. (1999) Science 284, 1365-1368
45. Wang, H., Chen, J., Hollister, K., Sowers, L. C., and Forman, B. M. (1999) Mol. Cell 3, 543-553
46. Makishima, M., Okamoto, A. Y., Repa, J. J., Tu, H., Learned, R. M., Luk, A., Hull, M. V., Lustig, K. D., Mangelsdorf, D. J., and Shan, B. (1999) Science 284, 1362-1365
47. Gupta, S., Stravitz, R. T., Dent, P., and Hyelmon, P. B. (2001) J. Biol. Chem. 276, 15816-15822
48. Goodwin, B., Jones, S. A., Price, R. R., Watson, M. A., McKee, D. D., Moore, L. B., Galardi, C., Wilson, J. G., Lewis, M. C., Roth, M. E., Maloney, P. R., Willson, T. M., and Kliewer, S. A. (2000) Mol. Cell 6, 517-526