Targeted disruption of the ζPKC gene results in the impairment of the NF-κB pathway

Molecular Cell

Volumn 8, Issue 4, 2001, Pages 771-780

  Leitges, Michael ^a   Sanz, Laura ^c   Martin, Pilar ^c   Duran, Angeles ^c   Braun, Uschi ^a   García, Juan F ^b   Camacho, Fanny ^b   Diaz Meco, María T ^c   Rennert, Paul D ^d   Moscat, Jorge ^c  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b Centro Nacional de Investigaciones Oncológicas   (Spain)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^d BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DIMER; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LYMPHOTOXIN; PROTEIN KINASE C; SYNAPTOTAGMIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; ACETYLCYSTEINE; CHUK PROTEIN, MOUSE; CYCLOHEXIMIDE; CYSTEINE PROTEINASE INHIBITOR; DNA BINDING PROTEIN; DRUG DERIVATIVE; I KAPPA B; I KAPPA B KINASE; IKBKB PROTEIN, MOUSE; IKBKE PROTEIN, MOUSE; LACTACYSTIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PROTEIN KINASE C ZETA; PROTEIN SERINE THREONINE KINASE; PROTEIN SYNTHESIS INHIBITOR; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INACTIVATION; FEMALE; FIBROBLAST; GENE DISRUPTION; LUNG; LYMPHOID ORGAN; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; APOPTOSIS; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE TARGETING; GENETIC TRANSCRIPTION; GENETICS; LYMPHOCYTE SUBPOPULATION; METABOLISM; MOUSE MUTANT; PEYER PATCH; PHOSPHORYLATION; PHYSIOLOGY; REPORTER GENE; SPLEEN;

ANIMALIA;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CYCLOHEXIMIDE; CYSTEINE PROTEINASE INHIBITORS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; GENE TARGETING; GENES, REPORTER; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INTERLEUKIN-1; LUNG; LYMPHOCYTE SUBSETS; MALE; MICE; MICE, KNOCKOUT; NF-KAPPA B; PEYER'S PATCHES; PHENOTYPE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SPLEEN; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 13944253118     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00361-6     Document Type: Article

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