Zinc is a potent inhibitor of the apoptotic protease, caspase-3: A novel target for zinc in the inhibition of apoptosis

Journal of Biological Chemistry

Volumn 272, Issue 30, 1997, Pages 18530-18533

  Perry, David K ^a   Smyth, Miriam J ^a,b   Stennicke, Henning R ^c   Salvesen, Guy S ^c   Duriez, Patrick ^d   Poirier, Guy G ^d   Hannun, Yusuf A ^a,e  

^a DUKE UNIVERSITY   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

^c BURNHAM INSTITUTE   (United States)

^d UNIVERSITÉ LAVAL   (Canada)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; ETOPOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEINASE; ZINC; ZINC FINGER PROTEIN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CELL FREE SYSTEM; CRYSTAL STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; REGULATORY MECHANISM;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASES; CATALYSIS; CATTLE; CELL-FREE SYSTEM; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENZYME PRECURSORS; ETOPOSIDE; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; TUMOR CELLS, CULTURED; ZINC;

BOVINAE;

EID: 0030855488     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.30.18530     Document Type: Article

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